NO20010046L - Dolastatin-15-derivater - Google Patents

Dolastatin-15-derivater

Info

Publication number
NO20010046L
NO20010046L NO20010046A NO20010046A NO20010046L NO 20010046 L NO20010046 L NO 20010046L NO 20010046 A NO20010046 A NO 20010046A NO 20010046 A NO20010046 A NO 20010046A NO 20010046 L NO20010046 L NO 20010046L
Authority
NO
Norway
Prior art keywords
dolastatin
derivatives
Prior art date
Application number
NO20010046A
Other languages
English (en)
Other versions
NO20010046D0 (no
Inventor
Kurt Ritter
Bernd Janssen
Andreas Haupt
Andreas Kling
Teresa Barlozzari
Wilhelm Amberg
Original Assignee
Basf Biores Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Basf Biores Corp filed Critical Basf Biores Corp
Publication of NO20010046D0 publication Critical patent/NO20010046D0/no
Publication of NO20010046L publication Critical patent/NO20010046L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/02—Linear peptides containing at least one abnormal peptide link
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10—Tetrapeptides
    • C07K5/1002—Tetrapeptides with the first amino acid being neutral
    • C07K5/1005—Tetrapeptides with the first amino acid being neutral and aliphatic
    • C07K5/101—Tetrapeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms, e.g. Val, Ile, Leu
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10—Tetrapeptides
    • C07K5/1024—Tetrapeptides with the first amino acid being heterocyclic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
NO20010046A 1998-07-08 2001-01-04 Dolastatin-15-derivater NO20010046L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/112,249 US5985837A (en) 1998-07-08 1998-07-08 Dolastatin 15 derivatives
PCT/US1999/014099 WO2000002906A1 (en) 1998-07-08 1999-06-23 Dolastatin 15 derivatives

Publications (2)

Publication Number Publication Date
NO20010046D0 NO20010046D0 (no) 2001-01-04
NO20010046L true NO20010046L (no) 2001-03-02

Family

ID=22342878

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20010046A NO20010046L (no) 1998-07-08 2001-01-04 Dolastatin-15-derivater

Country Status (14)

Country Link
US (2) US5985837A (no)
EP (1) EP1093460A1 (no)
JP (1) JP2002520335A (no)
KR (1) KR20010053428A (no)
CN (1) CN1312817A (no)
AU (1) AU4708199A (no)
BR (1) BR9911932A (no)
CA (1) CA2332641A1 (no)
HK (1) HK1041007A1 (no)
HU (1) HUP0103560A3 (no)
IL (1) IL140578A0 (no)
NO (1) NO20010046L (no)
WO (1) WO2000002906A1 (no)
ZA (1) ZA200100169B (no)

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WO2012145112A2 (en) 2011-04-18 2012-10-26 Immunogen, Inc. Novel maytansinoid derivatives with sulfoxide linker
MY168297A (en) 2011-11-17 2018-10-23 Pfizer Cytotoxic Peptides and Antibody Drug Conjugates Thereof
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WO2017058808A1 (en) * 2015-10-02 2017-04-06 Sirenas Llc Anti-cancer compounds and conjugates thereof
US10918627B2 (en) 2016-05-11 2021-02-16 Massachusetts Institute Of Technology Convergent and enantioselective total synthesis of Communesin analogs
WO2018209239A1 (en) 2017-05-11 2018-11-15 Massachusetts Institute Of Technology Potent agelastatin derivatives as modulators for cancer invasion and metastasis
US10640508B2 (en) 2017-10-13 2020-05-05 Massachusetts Institute Of Technology Diazene directed modular synthesis of compounds with quaternary carbon centers
US11535634B2 (en) 2019-06-05 2022-12-27 Massachusetts Institute Of Technology Compounds, conjugates, and compositions of epipolythiodiketopiperazines and polythiodiketopiperazines and uses thereof
WO2022182415A1 (en) 2021-02-24 2022-09-01 Massachusetts Institute Of Technology Himastatin derivatives, and processes of preparation thereof, and uses thereof
JP7717832B2 (ja) 2021-04-10 2025-08-04 ジェンマブ エー／エス Ｆｏｌｒ１結合剤、そのコンジュゲートおよびこれを使用する方法
WO2022226317A1 (en) 2021-04-23 2022-10-27 Profoundbio Us Co. Anti-cd70 antibodies, conjugates thereof and methods of using the same
TW202320857A (zh) 2021-07-06 2023-06-01 美商普方生物製藥美國公司 連接子、藥物連接子及其結合物及其使用方法
MX2024002571A (es) 2021-09-03 2024-03-20 Toray Industries Composicion farmaceutica para tratamiento y/o prevencion de cancer.
AU2024353316A1 (en) 2023-09-26 2026-03-26 Genmab A/S Ptk7 binding agents, conjugates thereof and methods of using the same
WO2025149661A1 (en) 2024-01-10 2025-07-17 Genmab A/S Slitrk6 binding agents, conjugates thereof and methods of using the same
WO2025181219A1 (en) 2024-02-29 2025-09-04 Genmab A/S Egfr and c-met bispecific binding agents, conjugates thereof and methods of using the same

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Also Published As

Publication number Publication date
JP2002520335A (ja) 2002-07-09
HUP0103560A3 (en) 2002-05-28
ZA200100169B (en) 2002-01-08
HK1041007A1 (zh) 2002-06-28
NO20010046D0 (no) 2001-01-04
EP1093460A1 (en) 2001-04-25
WO2000002906A1 (en) 2000-01-20
BR9911932A (pt) 2001-10-16
CA2332641A1 (en) 2000-01-20
KR20010053428A (ko) 2001-06-25
AU4708199A (en) 2000-02-01
CN1312817A (zh) 2001-09-12
US20010018422A1 (en) 2001-08-30
HUP0103560A2 (hu) 2002-02-28
IL140578A0 (en) 2002-02-10
US5985837A (en) 1999-11-16

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Legal Events

Date Code Title Description
FC2A Withdrawal, rejection or dismissal of laid open patent application
FC2A Withdrawal, rejection or dismissal of laid open patent application