|
US6541498B2
(en)
|
1993-05-20 |
2003-04-01 |
Texas Biotechnology |
Benzenesulfonamides and the use thereof to modulate the activity of endothelin
|
|
WO2000001389A1
(en)
*
|
1998-07-06 |
2000-01-13 |
Bristol-Myers Squibb Co. |
Biphenyl sulfonamides as dual angiotensin endothelin receptor antagonists
|
|
MY125533A
(en)
|
1999-12-06 |
2006-08-30 |
Bristol Myers Squibb Co |
Heterocyclic dihydropyrimidine compounds
|
|
DE60030764T2
(de)
*
|
1999-12-15 |
2007-09-13 |
Bristol-Myers Squibb Co. |
Biphenyl - sulfonamide als duale angiotensin - endothelin - rezeptor - antagonisten
|
|
AU2456701A
(en)
*
|
1999-12-31 |
2001-07-16 |
Texas Biotechnology Corporation |
Pharmaceutical and veterinary uses of endothelin antagonists
|
|
US6271228B1
(en)
*
|
2000-04-28 |
2001-08-07 |
Pfizer Inc. |
Blood pressure stabilization during hemodialysis
|
|
US7622503B2
(en)
|
2000-08-24 |
2009-11-24 |
University Of Tennessee Research Foundation |
Selective androgen receptor modulators and methods of use thereof
|
|
US20040087484A1
(en)
*
|
2000-12-01 |
2004-05-06 |
Sahota Pritam Singh |
Combination of organic compounds
|
|
CA2461202C
(en)
|
2001-09-21 |
2011-07-12 |
Donald Pinto |
Lactam-containing compounds and derivatives thereof as factor xa inhibitors
|
|
CA2463908A1
(en)
|
2001-10-18 |
2003-04-24 |
Bristol-Myers Squibb Company |
Human glucagon-like-peptide-1 mimics and their use in the treatment of diabetes and related conditions
|
|
US7238671B2
(en)
|
2001-10-18 |
2007-07-03 |
Bristol-Myers Squibb Company |
Human glucagon-like-peptide-1 mimics and their use in the treatment of diabetes and related conditions
|
|
US8853266B2
(en)
|
2001-12-06 |
2014-10-07 |
University Of Tennessee Research Foundation |
Selective androgen receptor modulators for treating diabetes
|
|
US6831102B2
(en)
|
2001-12-07 |
2004-12-14 |
Bristol-Myers Squibb Company |
Phenyl naphthol ligands for thyroid hormone receptor
|
|
TWI328007B
(en)
|
2002-01-16 |
2010-08-01 |
Astrazeneca Ab |
Novel compounds
|
|
TW200307539A
(en)
|
2002-02-01 |
2003-12-16 |
Bristol Myers Squibb Co |
Cycloalkyl inhibitors of potassium channel function
|
|
US7435824B2
(en)
|
2002-04-19 |
2008-10-14 |
Bristol-Myers Squibb Company |
Prodrugs of potassium channel inhibitors
|
|
TW200403058A
(en)
|
2002-04-19 |
2004-03-01 |
Bristol Myers Squibb Co |
Heterocyclo inhibitors of potassium channel function
|
|
US7405234B2
(en)
|
2002-05-17 |
2008-07-29 |
Bristol-Myers Squibb Company |
Bicyclic modulators of androgen receptor function
|
|
US7057046B2
(en)
|
2002-05-20 |
2006-06-06 |
Bristol-Myers Squibb Company |
Lactam glycogen phosphorylase inhibitors and method of use
|
|
MY139563A
(en)
|
2002-09-04 |
2009-10-30 |
Bristol Myers Squibb Co |
Heterocyclic aromatic compounds useful as growth hormone secretagogues
|
|
DE60332856D1
(de)
|
2002-10-23 |
2010-07-15 |
Bristol Myers Squibb Co |
Auf glycinnitril basierende hemmer der dipeptidylpeptidase iv
|
|
US7098235B2
(en)
|
2002-11-14 |
2006-08-29 |
Bristol-Myers Squibb Co. |
Triglyceride and triglyceride-like prodrugs of glycogen phosphorylase inhibiting compounds
|
|
US7632858B2
(en)
|
2002-11-15 |
2009-12-15 |
Bristol-Myers Squibb Company |
Open chain prolyl urea-related modulators of androgen receptor function
|
|
TW200504021A
(en)
|
2003-01-24 |
2005-02-01 |
Bristol Myers Squibb Co |
Substituted anilide ligands for the thyroid receptor
|
|
US6846836B2
(en)
|
2003-04-18 |
2005-01-25 |
Bristol-Myers Squibb Company |
N-substituted phenylurea inhibitors of mitochondrial F1F0 ATP hydrolase
|
|
US7557143B2
(en)
|
2003-04-18 |
2009-07-07 |
Bristol-Myers Squibb Company |
Thyroid receptor ligands
|
|
US6995183B2
(en)
|
2003-08-01 |
2006-02-07 |
Bristol Myers Squibb Company |
Adamantylglycine-based inhibitors of dipeptidyl peptidase IV and methods
|
|
US7820702B2
(en)
|
2004-02-04 |
2010-10-26 |
Bristol-Myers Squibb Company |
Sulfonylpyrrolidine modulators of androgen receptor function and method
|
|
US7378426B2
(en)
|
2004-03-01 |
2008-05-27 |
Bristol-Myers Squibb Company |
Fused heterotricyclic compounds as inhibitors of 17β-hydroxysteroid dehydrogenase 3
|
|
US7696241B2
(en)
|
2004-03-04 |
2010-04-13 |
Bristol-Myers Squibb Company |
Bicyclic compounds as modulators of androgen receptor function and method
|
|
US7625923B2
(en)
|
2004-03-04 |
2009-12-01 |
Bristol-Myers Squibb Company |
Bicyclic modulators of androgen receptor function
|
|
US7772232B2
(en)
|
2004-04-15 |
2010-08-10 |
Bristol-Myers Squibb Company |
Quinazolinyl compounds as inhibitors of potassium channel function
|
|
US7550499B2
(en)
|
2004-05-12 |
2009-06-23 |
Bristol-Myers Squibb Company |
Urea antagonists of P2Y1 receptor useful in the treatment of thrombotic conditions
|
|
US9889110B2
(en)
|
2004-06-07 |
2018-02-13 |
University Of Tennessee Research Foundation |
Selective androgen receptor modulator for treating hormone-related conditions
|
|
US9884038B2
(en)
|
2004-06-07 |
2018-02-06 |
University Of Tennessee Research Foundation |
Selective androgen receptor modulator and methods of use thereof
|
|
US7145040B2
(en)
|
2004-07-02 |
2006-12-05 |
Bristol-Myers Squibb Co. |
Process for the preparation of amino acids useful in the preparation of peptide receptor modulators
|
|
US7534763B2
(en)
|
2004-07-02 |
2009-05-19 |
Bristol-Myers Squibb Company |
Sustained release GLP-1 receptor modulators
|
|
TW200611704A
(en)
|
2004-07-02 |
2006-04-16 |
Bristol Myers Squibb Co |
Human glucagon-like-peptide-1 modulators and their use in the treatment of diabetes and related conditions
|
|
US7572805B2
(en)
|
2004-07-14 |
2009-08-11 |
Bristol-Myers Squibb Company |
Pyrrolo(oxo)isoquinolines as 5HT ligands
|
|
US7754755B2
(en)
|
2004-09-23 |
2010-07-13 |
Bristol-Myers Squibb Company |
Inhibitors of 15-lipoxygenase
|
|
AR051446A1
(es)
|
2004-09-23 |
2007-01-17 |
Bristol Myers Squibb Co |
Glucosidos de c-arilo como inhibidores selectivos de transportadores de glucosa (sglt2)
|
|
US7429611B2
(en)
|
2004-09-23 |
2008-09-30 |
Bristol-Myers Squibb Company |
Indole inhibitors of 15-lipoxygenase
|
|
US7517991B2
(en)
|
2004-10-12 |
2009-04-14 |
Bristol-Myers Squibb Company |
N-sulfonylpiperidine cannabinoid receptor 1 antagonists
|
|
US8143425B2
(en)
|
2004-10-12 |
2012-03-27 |
Bristol-Myers Squibb Company |
Heterocyclic aromatic compounds useful as growth hormone secretagogues
|
|
US7446210B2
(en)
|
2004-10-26 |
2008-11-04 |
Janssen Pharmaceutica N.V. |
Factor Xa compounds
|
|
US7635699B2
(en)
|
2004-12-29 |
2009-12-22 |
Bristol-Myers Squibb Company |
Azolopyrimidine-based inhibitors of dipeptidyl peptidase IV and methods
|
|
US7589088B2
(en)
|
2004-12-29 |
2009-09-15 |
Bristol-Myers Squibb Company |
Pyrimidine-based inhibitors of dipeptidyl peptidase IV and methods
|
|
WO2006076598A2
(en)
|
2005-01-12 |
2006-07-20 |
Bristol-Myers Squibb Company |
Bicyclic heterocycles as cannabinoid receptor modulators
|
|
US7368458B2
(en)
|
2005-01-12 |
2008-05-06 |
Bristol-Myers Squibb Company |
Bicyclic heterocycles as cannabinoid receptor modulators
|
|
WO2006076568A2
(en)
|
2005-01-12 |
2006-07-20 |
Bristol-Myers Squibb Company |
Thiazolopyridines as cannabinoid receptor modulators
|
|
WO2006076575A2
(en)
|
2005-01-13 |
2006-07-20 |
Bristol-Myers Squibb Company |
Substituted biaryl compounds as factor xia inhibitors
|
|
WO2006078697A1
(en)
|
2005-01-18 |
2006-07-27 |
Bristol-Myers Squibb Company |
Bicyclic heterocycles as cannabinoid receptor modulators
|
|
EP1954696B1
(en)
|
2005-01-19 |
2011-02-23 |
Bristol-Myers Squibb Company |
2-phenoxy-n-(1,3,4-thiadizol-2-yl)pyridin-3-amine derivatives and related compounds as p2y1 receptor inhibitors for the treatment of thromboembolic disorders
|
|
WO2006086464A2
(en)
|
2005-02-10 |
2006-08-17 |
Bristol-Myers Squibb Company |
Dihydroquinazolinones as 5ht modulators
|
|
EP2527337A1
(en)
|
2005-04-14 |
2012-11-28 |
Bristol-Myers Squibb Company |
Inhibitors of 11-beta hydroxysteroid dehydrogenase type I
|
|
US7521557B2
(en)
|
2005-05-20 |
2009-04-21 |
Bristol-Myers Squibb Company |
Pyrrolopyridine-based inhibitors of dipeptidyl peptidase IV and methods
|
|
TW200726765A
(en)
|
2005-06-17 |
2007-07-16 |
Bristol Myers Squibb Co |
Triazolopyridine cannabinoid receptor 1 antagonists
|
|
US7317012B2
(en)
|
2005-06-17 |
2008-01-08 |
Bristol-Myers Squibb Company |
Bicyclic heterocycles as cannabinoind-1 receptor modulators
|
|
US7629342B2
(en)
|
2005-06-17 |
2009-12-08 |
Bristol-Myers Squibb Company |
Azabicyclic heterocycles as cannabinoid receptor modulators
|
|
US7452892B2
(en)
|
2005-06-17 |
2008-11-18 |
Bristol-Myers Squibb Company |
Triazolopyrimidine cannabinoid receptor 1 antagonists
|
|
US7632837B2
(en)
|
2005-06-17 |
2009-12-15 |
Bristol-Myers Squibb Company |
Bicyclic heterocycles as cannabinoid-1 receptor modulators
|
|
DE602006020871D1
(de)
|
2005-06-27 |
2011-05-05 |
Bristol Myers Squibb Co |
Lineare harnstoffmimetika-antagonisten des p2y1-rezeptors zur behandlung von thromboseleiden
|
|
WO2007002634A1
(en)
|
2005-06-27 |
2007-01-04 |
Bristol-Myers Squibb Company |
Carbocycle and heterocycle antagonists of p2y1 receptor useful in the treatment of thrombotic conditions
|
|
AR056867A1
(es)
|
2005-06-27 |
2007-10-31 |
Bristol Myers Squibb Co |
Antagonistas heterociclicos n- enlazados del receptor de p2y1 utiles en el tratamiento de condiciones tromboticas. composiciones farmaceuticas.
|
|
EP1899299B1
(en)
|
2005-06-27 |
2010-10-20 |
Bristol-Myers Squibb Company |
C-linked cyclic antagonists of p2y1 receptor useful in the treatment of thrombotic conditions
|
|
WO2007005967A2
(en)
*
|
2005-07-05 |
2007-01-11 |
Teva Pharmaceutical Industries Ltd. |
Process for preparing valsartan
|
|
EP1757290A1
(en)
|
2005-08-16 |
2007-02-28 |
Zentaris GmbH |
Novel triazole derivatives as ghrelin analogue ligands of growth hormone secretagogue receptors
|
|
US7795436B2
(en)
|
2005-08-24 |
2010-09-14 |
Bristol-Myers Squibb Company |
Substituted tricyclic heterocycles as serotonin receptor agonists and antagonists
|
|
US7534804B2
(en)
|
2005-08-24 |
2009-05-19 |
Bristol-Myers Squibb Company |
Benzoxazole inhibitors of 15-lipoxygenase
|
|
JP2009506119A
(ja)
|
2005-08-31 |
2009-02-12 |
ユニバーシティ オブ テネシー リサーチ ファウンデーション |
選択的アンドロゲン受容体モジュレーターを用いる腎疾患、熱傷、創傷および脊髄損傷の処置
|
|
US8618115B2
(en)
|
2005-10-26 |
2013-12-31 |
Bristol-Myers Squibb Company |
Substituted thieno[3,2-d]pyrimidinones as MCHR1 antagonists and methods for using them
|
|
EP1943215A2
(en)
|
2005-10-31 |
2008-07-16 |
Brystol-Myers Squibb Company |
Pyrrolidinyl beta-amino amide-based inhibitors of dipeptidyl peptidase iv and methods
|
|
US7553836B2
(en)
|
2006-02-06 |
2009-06-30 |
Bristol-Myers Squibb Company |
Melanin concentrating hormone receptor-1 antagonists
|
|
MX2008011227A
(es)
*
|
2006-03-03 |
2009-02-10 |
Torrent Pharmaceuticals Ltd |
Receptores antagonistas de accion nueva y doble en los receptores at1 y eta.
|
|
WO2007109456A2
(en)
*
|
2006-03-16 |
2007-09-27 |
Pharmacopeia, Inc. |
Substituted biphenyl isoxazole sulfonamides as dual angiotensin endothelin receptor antagonists
|
|
US20100022457A1
(en)
|
2006-05-26 |
2010-01-28 |
Bristol-Myers Squibb Company |
Sustained release glp-1 receptor modulators
|
|
US7919598B2
(en)
|
2006-06-28 |
2011-04-05 |
Bristol-Myers Squibb Company |
Crystal structures of SGLT2 inhibitors and processes for preparing same
|
|
PT2038252T
(pt)
|
2006-07-12 |
2016-12-16 |
Univ Tennessee Res Found |
Acilanilidos substituidos e métodos de utilização dos mesmos
|
|
US7727978B2
(en)
|
2006-08-24 |
2010-06-01 |
Bristol-Myers Squibb Company |
Cyclic 11-beta hydroxysteroid dehydrogenase type I inhibitors
|
|
CN101522676A
(zh)
|
2006-10-05 |
2009-09-02 |
Cv医药有限公司 |
用作硬脂酰-CoA脱氢酶抑制剂的双环含氮杂环化合物
|
|
US7960569B2
(en)
|
2006-10-17 |
2011-06-14 |
Bristol-Myers Squibb Company |
Indole antagonists of P2Y1 receptor useful in the treatment of thrombotic conditions
|
|
US9623021B2
(en)
|
2007-01-22 |
2017-04-18 |
Gtx, Inc. |
Nuclear receptor binding agents
|
|
ES2475193T3
(es)
|
2007-01-22 |
2014-07-10 |
Gtx, Inc. |
Agentes de unión al receptor nuclear
|
|
US9604931B2
(en)
|
2007-01-22 |
2017-03-28 |
Gtx, Inc. |
Nuclear receptor binding agents
|
|
TW200838501A
(en)
*
|
2007-02-02 |
2008-10-01 |
Theravance Inc |
Dual-acting antihypertensive agents
|
|
AR065809A1
(es)
|
2007-03-22 |
2009-07-01 |
Bristol Myers Squibb Co |
Formulaciones farmaceuticas que contienen un inhibidor sglt2
|
|
US20080255161A1
(en)
*
|
2007-04-11 |
2008-10-16 |
Dmitry Koltun |
3-HYDROQUINAZOLIN-4-ONE DERIVATIVES FOR USE AS STEAROYL CoA DESATURASE INHIBITORS
|
|
US8546394B2
(en)
|
2007-04-17 |
2013-10-01 |
Bristol-Myers Squibb Company |
Substituted [1,2,4]triazolo[4,3-A]pyrazine 11-beta-hydroxysteroid dehydrogenase inhibitors
|
|
PE20090696A1
(es)
|
2007-04-20 |
2009-06-20 |
Bristol Myers Squibb Co |
Formas cristalinas de saxagliptina y procesos para preparar las mismas
|
|
KR20100015886A
(ko)
|
2007-04-23 |
2010-02-12 |
사노피-아벤티스 |
P2y12 길항제로서의 퀴놀린-카복스아미드 유도체
|
|
TWI448284B
(zh)
|
2007-04-24 |
2014-08-11 |
Theravance Inc |
雙效抗高血壓劑
|
|
CN101668756A
(zh)
|
2007-05-04 |
2010-03-10 |
百时美施贵宝公司 |
[6,6]和[6,7]-双环gpr119 g蛋白偶合受体激动剂
|
|
WO2008137436A1
(en)
|
2007-05-04 |
2008-11-13 |
Bristol-Myers Squibb Company |
[6,5]-bicyclic gpr119 g protein-coupled receptor agonists
|
|
TWI406850B
(zh)
|
2007-06-05 |
2013-09-01 |
Theravance Inc |
雙效苯并咪唑抗高血壓劑
|
|
US20090011994A1
(en)
|
2007-07-06 |
2009-01-08 |
Bristol-Myers Squibb Company |
Non-basic melanin concentrating hormone receptor-1 antagonists and methods
|
|
SI2170864T1
(sl)
|
2007-07-17 |
2012-04-30 |
Bristol Myers Squibb Co |
Piridon gpr119g proteinsko povezani receptorski antagonisti
|
|
CN101808995A
(zh)
|
2007-07-27 |
2010-08-18 |
百时美施贵宝公司 |
新颖的葡糖激酶激活剂及其使用方法
|
|
JP2010538071A
(ja)
|
2007-09-07 |
2010-12-09 |
セラヴァンス, インコーポレーテッド |
二重作用性降圧剤
|
|
US7968603B2
(en)
|
2007-09-11 |
2011-06-28 |
University Of Tennessee Research Foundation |
Solid forms of selective androgen receptor modulators
|
|
RU2443699C2
(ru)
|
2007-09-20 |
2012-02-27 |
Айрм Ллк |
Соединения и композиции в качестве модуляторов активности gpr119
|
|
JP2011506459A
(ja)
|
2007-12-11 |
2011-03-03 |
セラヴァンス, インコーポレーテッド |
抗高血圧剤としての二重作用性ベンゾイミダゾール誘導体およびその使用
|
|
EP2238128B1
(en)
|
2007-12-26 |
2012-08-22 |
Sanofi |
Heterocyclic pyrazole-carboxamides as p2y12 antagonists
|
|
EP2103602A1
(en)
|
2008-03-17 |
2009-09-23 |
AEterna Zentaris GmbH |
Novel 1,2,4-triazole derivatives and process of manufacturing thereof
|
|
EP2297113A1
(en)
|
2008-04-29 |
2011-03-23 |
Theravance, Inc. |
Dual-acting antihypertensive agents
|
|
EP2805939B1
(en)
|
2008-05-19 |
2018-06-27 |
Merck Sharp & Dohme Corp. |
Heterocyclic compounds as factor IXA inhibitors.
|
|
PE20091928A1
(es)
|
2008-05-29 |
2009-12-31 |
Bristol Myers Squibb Co |
Tienopirimidinas hidroxisustituidas como antagonistas de receptor-1 de hormona concentradora de melanina no basicos
|
|
WO2009155448A1
(en)
*
|
2008-06-20 |
2009-12-23 |
Ligand Pharmaceuticals Inc. |
Biphenyl sulfonamides as dual angiotensin endothelin receptor antagonists
|
|
TW201006821A
(en)
|
2008-07-16 |
2010-02-16 |
Bristol Myers Squibb Co |
Pyridone and pyridazone analogues as GPR119 modulators
|
|
WO2010011821A2
(en)
|
2008-07-24 |
2010-01-28 |
Theravance, Inc. |
Dual-acting antihypertensive agents
|
|
US8557983B2
(en)
|
2008-12-04 |
2013-10-15 |
Abbvie Inc. |
Apoptosis-inducing agents for the treatment of cancer and immune and autoimmune diseases
|
|
US20100160322A1
(en)
|
2008-12-04 |
2010-06-24 |
Abbott Laboratories |
Apoptosis-inducing agents for the treatment of cancer and immune and autoimmune diseases
|
|
US8563735B2
(en)
|
2008-12-05 |
2013-10-22 |
Abbvie Inc. |
Bcl-2-selective apoptosis-inducing agents for the treatment of cancer and immune diseases
|
|
US8586754B2
(en)
|
2008-12-05 |
2013-11-19 |
Abbvie Inc. |
BCL-2-selective apoptosis-inducing agents for the treatment of cancer and immune diseases
|
|
WO2010106988A1
(ja)
*
|
2009-03-17 |
2010-09-23 |
第一三共株式会社 |
アミド誘導体
|
|
SG174504A1
(en)
|
2009-03-27 |
2011-10-28 |
Bristol Myers Squibb Co |
Methods for preventing major adverse cardiovascular events with dpp-iv inhibitors
|
|
EP3708163A1
(en)
|
2009-03-31 |
2020-09-16 |
Ligand Pharmaceuticals, Inc. |
Use of sparsentan for the treatment of chronic inflammatory diseases
|
|
US9034875B2
(en)
|
2009-05-26 |
2015-05-19 |
Abbvie Inc. |
Apoptosis-inducing agents for the treatment of cancer and immune and autoimmune diseases
|
|
NZ595708A
(en)
*
|
2009-05-26 |
2014-03-28 |
Abbvie Bahamas Ltd |
Apoptosis-inducing agents for the treatment of cancer and immune and autoimmune diseases
|
|
US8546399B2
(en)
|
2009-05-26 |
2013-10-01 |
Abbvie Inc. |
Apoptosis inducing agents for the treatment of cancer and immune and autoimmune diseases
|
|
US20220315555A1
(en)
|
2009-05-26 |
2022-10-06 |
Abbvie Inc. |
Apoptosis inducing agents for the treatment of cancer and immune and autoimmune diseases
|
|
SMT202000093T1
(it)
|
2009-06-16 |
2020-03-13 |
Pfizer |
Forme di dosaggio di apixaban
|
|
EP2451782B1
(en)
|
2009-07-07 |
2016-11-09 |
Theravance Biopharma R&D IP, LLC |
Dual-acting pyrazole antihypertensive agents
|
|
JP2012533626A
(ja)
|
2009-07-22 |
2012-12-27 |
セラヴァンス, インコーポレーテッド |
二重作用オキサゾール降圧剤
|
|
WO2011014520A2
(en)
|
2009-07-29 |
2011-02-03 |
Irm Llc |
Compounds and compositions as modulators of gpr119 activity
|
|
WO2011017296A1
(en)
|
2009-08-04 |
2011-02-10 |
Schering Corporation |
4, 5, 6-trisubstituted pyrimidine derivatives as factor ixa inhibitors
|
|
CN102686579A
(zh)
|
2009-10-09 |
2012-09-19 |
Irm责任有限公司 |
作为gpr119活性调节剂的化合物和组合物
|
|
JP5784623B2
(ja)
|
2009-11-13 |
2015-09-24 |
アストラゼネカ・アクチエボラーグAstrazeneca Aktiebolag |
速放性錠剤製剤
|
|
EP3315124B1
(en)
|
2009-11-13 |
2021-01-06 |
Astrazeneca AB |
Bilayer tablet formulations
|
|
CN102711738A
(zh)
|
2009-11-13 |
2012-10-03 |
百时美施贵宝公司 |
质量得以减小的二甲双胍制剂
|
|
CN101891735B
(zh)
*
|
2009-11-25 |
2012-07-18 |
北京理工大学 |
联苯磺胺异噁唑类化合物、合成方法及用途
|
|
CN101921265B
(zh)
*
|
2009-11-25 |
2012-07-04 |
北京理工大学 |
联苯酰胺四唑类化合物、合成方法及用途
|
|
US8394858B2
(en)
|
2009-12-03 |
2013-03-12 |
Novartis Ag |
Cyclohexane derivatives and uses thereof
|
|
WO2011090929A1
(en)
|
2010-01-19 |
2011-07-28 |
Theravance, Inc. |
Dual-acting thiophene, pyrrole, thiazole and furan antihypertensive agents
|
|
TWI562775B
(en)
|
2010-03-02 |
2016-12-21 |
Lexicon Pharmaceuticals Inc |
Methods of using inhibitors of sodium-glucose cotransporters 1 and 2
|
|
MX2012011460A
(es)
|
2010-04-08 |
2012-11-23 |
Squibb Bristol Myers Co |
Analogos de pirimidinilpiperidiniloxipiridinona como moduladores de gpr119.
|
|
US8592396B2
(en)
|
2010-04-14 |
2013-11-26 |
Bristol-Myers Squibb Company |
Glucokinase activators and methods of using same
|
|
CA2798610A1
(en)
|
2010-05-06 |
2011-11-10 |
Bristol-Myers Squibb Company |
Bicyclic heteroaryl compounds as gpr119 modulators
|
|
WO2011140161A1
(en)
|
2010-05-06 |
2011-11-10 |
Bristol-Myers Squibb Company |
Benzofuranyl analogues as gpr119 modulators
|
|
US8697739B2
(en)
|
2010-07-29 |
2014-04-15 |
Novartis Ag |
Bicyclic acetyl-CoA carboxylase inhibitors and uses thereof
|
|
EP2431035A1
(en)
|
2010-09-16 |
2012-03-21 |
Æterna Zentaris GmbH |
Novel Triazole Derivatives with Improved Receptor Activity and Bioavailability Properties as Ghrelin Antagonists of Growth Hormone Secretagogue Receptors
|
|
UA113500C2
(xx)
|
2010-10-29 |
2017-02-10 |
|
Одержані екструзією розплаву тверді дисперсії, що містять індукуючий апоптоз засіб
|
|
CA3152557A1
(en)
|
2010-10-29 |
2012-05-03 |
Abbvie Inc. |
Solid dispersions containing an apoptosis-inducing agent
|
|
TWI620736B
(zh)
|
2010-11-23 |
2018-04-11 |
艾伯維巴哈馬有限公司 |
使用選擇性bcl-2抑制劑之治療方法
|
|
PT2643322T
(pt)
|
2010-11-23 |
2017-11-13 |
Abbvie Inc |
Sais e formas cristalinas de um agente indutor de apoptose
|
|
PH12013501345A1
(en)
|
2010-12-23 |
2022-10-24 |
Purdue Pharma Lp |
Tamper resistant solid oral dosage forms
|
|
TWI631963B
(zh)
|
2011-01-05 |
2018-08-11 |
雷西肯製藥股份有限公司 |
包含鈉-葡萄糖共同輸送體1與2之抑制劑的組合物與應用方法
|
|
MD20140044A2
(ro)
|
2011-11-11 |
2014-08-31 |
Pfizer Inc. |
2-Tiopirimidinone şi utilizarea lor pentru tratamentul afecţiunilor cardiovasculare
|
|
JP2015515472A
(ja)
|
2012-04-06 |
2015-05-28 |
ファイザー・インク |
ジアシルグリセロールアシルトランスフェラーゼ2阻害薬
|
|
US9174965B2
(en)
|
2012-05-16 |
2015-11-03 |
Bristol-Myers Squibb Company |
Pyrimidinylpiperidinyloxypyridone analogues as GPR119 modulators
|
|
SMT201800369T1
(it)
|
2012-06-11 |
2018-09-13 |
Bristol Myers Squibb Co |
Profarmaci di acido fosforamidico di 5-[5-fenil-4-piridin-2-il-metilammino)chinazolin-2-il}piridina-3-solfonammide
|
|
US10258596B2
(en)
|
2012-07-13 |
2019-04-16 |
Gtx, Inc. |
Method of treating HER2-positive breast cancers with selective androgen receptor modulators (SARMS)
|
|
US9744149B2
(en)
|
2012-07-13 |
2017-08-29 |
Gtx, Inc. |
Method of treating androgen receptor (AR)-positive breast cancers with selective androgen receptor modulator (SARMs)
|
|
US9622992B2
(en)
|
2012-07-13 |
2017-04-18 |
Gtx, Inc. |
Method of treating androgen receptor (AR)-positive breast cancers with selective androgen receptor modulator (SARMs)
|
|
US10987334B2
(en)
|
2012-07-13 |
2021-04-27 |
University Of Tennessee Research Foundation |
Method of treating ER mutant expressing breast cancers with selective androgen receptor modulators (SARMs)
|
|
PT2872482T
(pt)
|
2012-07-13 |
2020-09-22 |
Oncternal Therapeutics Inc |
Método de tratamento de cancro de mama com modulador seletivo do recetor de andrógeno (sarm)
|
|
US10314807B2
(en)
|
2012-07-13 |
2019-06-11 |
Gtx, Inc. |
Method of treating HER2-positive breast cancers with selective androgen receptor modulators (SARMS)
|
|
US9969683B2
(en)
|
2012-07-13 |
2018-05-15 |
Gtx, Inc. |
Method of treating estrogen receptor (ER)-positive breast cancers with selective androgen receptor modulator (SARMS)
|
|
LT6043B
(lt)
|
2012-08-27 |
2014-06-25 |
Uab "Mibarsas" |
Organinės trąšos sapropelio pagrindu ir jų gamybos būdas
|
|
EP2892896B1
(en)
|
2012-09-05 |
2016-06-29 |
Bristol-Myers Squibb Company |
Pyrrolone or pyrrolidinone melanin concentrating hormore receptor-1 antagonists
|
|
EP2892897A1
(en)
|
2012-09-05 |
2015-07-15 |
Bristol-Myers Squibb Company |
Pyrrolone or pyrrolidinone melanin concentrating hormone receptor-1 antagonists
|
|
WO2014052619A1
(en)
|
2012-09-27 |
2014-04-03 |
Irm Llc |
Piperidine derivatives and compositions as modulators of gpr119 activity
|
|
PL3489226T3
(pl)
|
2012-11-20 |
2021-08-02 |
Lexicon Pharmaceuticals, Inc. |
Inhibitory kotransportera glukozowo-sodowego 1
|
|
JP6386527B2
(ja)
|
2013-03-11 |
2018-09-05 |
ブリストル−マイヤーズ スクイブ カンパニーBristol−Myers Squibb Company |
カリウムイオンチャネル阻害剤としてのピロロピリダジン
|
|
US9050345B2
(en)
|
2013-03-11 |
2015-06-09 |
Bristol-Myers Squibb Company |
Pyrrolotriazines as potassium ion channel inhibitors
|
|
US9242966B2
(en)
|
2013-03-11 |
2016-01-26 |
Bristol-Myers Squibb Company |
Phthalazines as potassium ion channel inhibitors
|
|
EP2970294B1
(en)
|
2013-03-11 |
2016-12-28 |
Bristol-Myers Squibb Company |
Pyrrolotriazines as potassium ion channel inhibitors
|
|
EP2970199A1
(en)
|
2013-03-11 |
2016-01-20 |
Bristol-Myers Squibb Company |
Isoquinolines as potassium ion channel inhibitors
|
|
US20140275082A1
(en)
|
2013-03-14 |
2014-09-18 |
Abbvie Inc. |
Apoptosis-inducing agents for the treatment of cancer and immune and autoimmune diseases
|
|
KR102230461B1
(ko)
|
2013-03-15 |
2021-03-22 |
유니버시티 오브 써던 캘리포니아 |
엔지오텐신-관련 질환들의 치료를 위한 방법들, 화합물들 및 조성물들
|
|
ES2665153T3
(es)
|
2013-10-09 |
2018-04-24 |
Pfizer Inc. |
Antagonistas del receptor EP3 de prostaglandina
|
|
US9580422B2
(en)
|
2013-10-22 |
2017-02-28 |
Bristol-Myers Squibb Company |
Isotopically labeled triazolopyridine 11-beta hydroxysteroid dehydrogenase type I inhibitors
|
|
LT3119757T
(lt)
|
2014-03-17 |
2018-07-10 |
Pfizer Inc. |
Diacilglicerolio aciltransferazės 2 inhibitoriai, skirti panaudoti metabolinių ir susijusių ligų gydyme
|
|
MA39838B1
(fr)
|
2014-04-04 |
2019-05-31 |
Pfizer |
Composés bicycliques hétéroaryle ou aryle fusionnés et leur utilisation en tant qu'inhibiteurs irak4
|
|
WO2015160636A1
(en)
|
2014-04-16 |
2015-10-22 |
Merck Sharp & Dohme Corp. |
Factor ixa inhibitors
|
|
SG11201609050UA
(en)
|
2014-05-30 |
2016-12-29 |
Pfizer |
Carbonitrile derivatives as selective androgen receptor modulators
|
|
WO2016103097A1
(en)
|
2014-12-22 |
2016-06-30 |
Pfizer Inc. |
Antagonists of prostaglandin ep3 receptor
|
|
CN104761548B
(zh)
*
|
2015-04-27 |
2017-09-12 |
梯尔希(南京)药物研发有限公司 |
一种稳定同位素标记的二苯基磺酰胺类药物的制备方法
|
|
AU2016257179A1
(en)
|
2015-05-05 |
2017-11-02 |
Pfizer Inc. |
2-thiopyrimidinones
|
|
WO2016193844A1
(en)
|
2015-05-29 |
2016-12-08 |
Pfizer Inc. |
Novel heterocyclic compounds as inhibitors of vanin-1 enzyme
|
|
EP3766885B1
(en)
|
2015-06-17 |
2022-05-25 |
Pfizer Inc. |
Tricyclic compounds and their use as phosphodiesterase inhibitors
|
|
WO2016203335A1
(en)
|
2015-06-18 |
2016-12-22 |
Pfizer Inc. |
Novel pyrido[2,3-b]pyrazinones as bet-family bromodomain inhibitors
|
|
CA2995153A1
(en)
|
2015-08-13 |
2017-02-16 |
Pfizer Inc. |
Bicyclic-fused heteroaryl or aryl compounds
|
|
ES2865199T3
(es)
|
2015-08-27 |
2021-10-15 |
Pfizer |
Compuestos de heteroarilo o arilo condensados bicíclicos como moduladores de IRAK4
|
|
WO2017037567A1
(en)
|
2015-09-03 |
2017-03-09 |
Pfizer Inc. |
Regulators of frataxin
|
|
CN105481844A
(zh)
*
|
2015-12-08 |
2016-04-13 |
梁彦云 |
一种治疗高血压的药物组合物
|
|
SI3397631T1
(sl)
|
2015-12-29 |
2022-01-31 |
Pfizer Inc. |
Substituirani 3-azabiciklo(3.1.0)heksani kot zaviralci ketoheksokinaze
|
|
CN106188115A
(zh)
*
|
2016-07-13 |
2016-12-07 |
北京理工大学 |
廉价高效合成2‑二羟硼基‑n‑二甲异噁唑基‑n‑甲氧乙氧甲基苯磺酰胺的新方法
|
|
EP3484876A1
(en)
|
2016-07-14 |
2019-05-22 |
Pfizer Inc |
Novel pyrimidine carboxamides as inhibitors of vanin-1 enzyme
|
|
EP3487862A1
(en)
|
2016-07-22 |
2019-05-29 |
Bristol-Myers Squibb Company |
Glucokinase activators and methods of using same
|
|
AR109179A1
(es)
|
2016-08-19 |
2018-11-07 |
Pfizer |
Inhibidores de diacilglicerol aciltransferasa 2
|
|
JP2019530713A
(ja)
|
2016-10-13 |
2019-10-24 |
レトロフィン, インコーポレイテッド |
腎臓疾患または障害を処置するためのビフェニルスルホンアミド化合物
|
|
US10703723B2
(en)
|
2017-03-09 |
2020-07-07 |
Truly Translational Sweden Ab |
Prodrugs of sulfasalazine, pharmaceutical compositions thereof and their use in the treatment of autoimmune disease
|
|
EP3630188B1
(en)
|
2017-05-31 |
2021-08-25 |
Amplio Pharma AB |
A pharmaceutical composition comprising a combination of methotrexate and novobiocin, and the use of said composition in therapy
|
|
EP3488868B1
(en)
|
2017-11-23 |
2023-09-13 |
medac Gesellschaft für klinische Spezialpräparate mbH |
Pharmaceutical composition for oral administration containing sulfasalazine and / or a sulfasalazine organic salt, production process and use
|
|
EP3489222A1
(en)
|
2017-11-23 |
2019-05-29 |
medac Gesellschaft für klinische Spezialpräparate mbH |
Sulfasalazine salts, production processes and uses
|
|
CN109929806B
(zh)
|
2017-12-19 |
2020-05-08 |
北京吉源生物科技有限公司 |
一种表达glp1和fgf21的干细胞及其用途
|
|
WO2019133445A1
(en)
|
2017-12-28 |
2019-07-04 |
Inception Ibd, Inc. |
Aminothiazoles as inhibitors of vanin-1
|
|
BR112021000139A2
(pt)
|
2018-07-19 |
2021-04-06 |
Astrazeneca Ab |
Métodos de tratamento da hfpef empregando dapagliflozina e composições compreendendo a mesma
|
|
CR20210110A
(es)
|
2018-08-31 |
2021-05-13 |
Pfizer |
Combinaciones para tratamiento de ehna/ehgna y enfermedades relacionadas
|
|
US10968192B2
(en)
|
2018-09-26 |
2021-04-06 |
Lexicon Pharmaceuticals, Inc. |
Crystalline solid forms of N-(1-((2-(dimethylamino)ethyl)amino)-2-methyl-1-oxopropan-2-yl)-4-(4-(2-methyl-5-((2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(methylthio)tetrahydro-2H-pyran-2-yl)benzyl)phenyl)butanamide and methods of their synthesis
|
|
KR102902972B1
(ko)
|
2018-10-04 |
2025-12-22 |
트래버르 테라퓨틱스, 인코포레이티드 |
Iv형 콜라겐 질환의 치료를 위한 비페닐 설폰아미드 화합물
|
|
WO2020102575A1
(en)
|
2018-11-16 |
2020-05-22 |
Inception Ibd, Inc. |
Heterocyclic aminothiazoles and uses thereof
|
|
WO2020234726A1
(en)
|
2019-05-20 |
2020-11-26 |
Pfizer Inc. |
Combinations comprising benzodioxol as glp-1r agonists for use in the treatment of nash/nafld and related diseases
|
|
WO2020261144A1
(en)
|
2019-06-28 |
2020-12-30 |
Pfizer Inc. |
5-(thiophen-2-yl)-1h-tetrazole derivatives as bckdk inhibitors useful for treating various diseases
|
|
TW202115086A
(zh)
|
2019-06-28 |
2021-04-16 |
美商輝瑞大藥廠 |
Bckdk抑制劑
|
|
TWI771766B
(zh)
|
2019-10-04 |
2022-07-21 |
美商輝瑞股份有限公司 |
二醯基甘油醯基轉移酶2 抑制劑
|
|
CN119841865A
(zh)
|
2020-02-07 |
2025-04-18 |
加舒布鲁姆生物公司 |
杂环glp-1激动剂
|
|
JP2022058085A
(ja)
|
2020-02-24 |
2022-04-11 |
ファイザー・インク |
ジアシルグリセロールアシルトランスフェラーゼ2阻害剤とアセチル-CoAカルボキシラーゼ阻害剤との組合せ
|
|
FI4143183T3
(fi)
|
2020-04-29 |
2026-01-07 |
Gasherbrum Bio Inc |
Heterosyklisiä glp-1-agonisteja
|
|
MX2022015706A
(es)
|
2020-06-09 |
2023-01-24 |
Pfizer |
Antagonistas del receptor de melanocortina 4 y usos de estos.
|
|
AU2021202643B2
(en)
|
2020-07-27 |
2023-02-02 |
Astrazeneca Ab |
Methods of treating chronic kidney disease with dapagliflozin
|
|
TW202220672A
(zh)
|
2020-07-27 |
2022-06-01 |
瑞典商阿斯特捷利康公司 |
用達格列淨治療慢性腎臟病之方法
|
|
WO2022266370A1
(en)
|
2021-06-17 |
2022-12-22 |
Aria Pharmaceuticals, Inc. |
Sparsentan for treating idiopathic pulmonary fibrosis
|
|
WO2023275715A1
(en)
|
2021-06-30 |
2023-01-05 |
Pfizer Inc. |
Metabolites of selective androgen receptor modulators
|
|
MX2024000518A
(es)
*
|
2021-07-09 |
2024-01-31 |
Vicore Pharma Ab |
Nuevos compuestos selectivos de angiotensina ii.
|
|
US20250066337A1
(en)
|
2021-08-26 |
2025-02-27 |
Pfizer Inc. |
Amorphous Form of (S)-2-(5-((3-Ethoxypyridin-2-YL)Oxy)Pyridin-3-YL)-N-(Tetrahydrofuran-3-YL)Pyrimidine-5-Carboxamide
|
|
CN117836294A
(zh)
*
|
2021-08-26 |
2024-04-05 |
上海翰森生物医药科技有限公司 |
含芳环类生物拮抗剂、其制备方法和应用
|
|
CN118119617A
(zh)
*
|
2021-10-21 |
2024-05-31 |
年衍药业(上海)有限公司 |
一种双重拮抗剂及其用途
|
|
CR20240183A
(es)
|
2021-12-01 |
2024-06-07 |
Pfizer |
Inhibidores y/o degradadores de bckdk
|
|
ES3039638T3
(en)
|
2021-12-06 |
2025-10-23 |
Pfizer |
Melanocortin 4 receptor antagonists and uses thereof
|
|
US20250108065A1
(en)
|
2022-01-26 |
2025-04-03 |
Astrazeneca Ab |
Methods of treating prediabetes or reducing the risk of developing type 2 diabetes with dapagliflozin
|
|
CN119137124A
(zh)
|
2022-03-09 |
2024-12-13 |
加舒布鲁姆生物公司 |
杂环glp-1激动剂
|
|
WO2023198140A1
(en)
|
2022-04-14 |
2023-10-19 |
Gasherbrum Bio, Inc. |
Heterocyclic glp-1 agonists
|
|
WO2023224963A1
(en)
*
|
2022-05-16 |
2023-11-23 |
Aria Pharmaceuticals, Inc. |
Dual-acting angiotensin and endothelin receptor antagonists
|
|
IL319486A
(en)
|
2022-10-07 |
2025-05-01 |
Pfizer |
HSD17B13 Inhibitors and/or Retarders
|
|
US20240182468A1
(en)
|
2022-10-18 |
2024-06-06 |
Pfizer Inc. |
Compounds for the activation of ampk
|
|
AU2023364628A1
(en)
|
2022-10-18 |
2025-04-03 |
Pfizer Inc. |
Patatin-like phospholipase domain-containing protein 3 (pnpla3) modifiers
|
|
CN115745983A
(zh)
*
|
2022-11-23 |
2023-03-07 |
深圳信立泰药业股份有限公司 |
一种血管紧张肽和内皮肽受体拮抗剂及其应用
|
|
JP2026501171A
(ja)
|
2022-12-15 |
2026-01-14 |
ガシャーブラム・バイオ・インコーポレイテッド |
Glp-1アゴニスト活性を有する化合物の塩および固体形態
|
|
KR20250117453A
(ko)
|
2022-12-16 |
2025-08-04 |
화이자 인코포레이티드 |
3-플루오로-4-하이드록시벤즈아미드-함유 억제제 및/또는 분해제 및 이의 용도
|
|
CN120752231A
(zh)
*
|
2023-02-24 |
2025-10-03 |
江苏豪森药业集团有限公司 |
含芳环类衍生物拮抗剂的盐、其制备方法和应用
|
|
EP4695226A1
(en)
|
2023-04-14 |
2026-02-18 |
Pfizer Inc. |
Glucose-dependent insulinotropic polypeptide receptor antagonists and uses thereof
|
|
CN116731004B
(zh)
*
|
2023-06-08 |
2025-11-25 |
李能刚 |
作为血管紧张素和内皮素受体双重拮抗剂的联苯磺酰胺
|
|
WO2025099566A1
(en)
|
2023-11-08 |
2025-05-15 |
Pfizer Inc. |
A crystalline form of 6-fluoro-3-(2,4,5-trifluoro-3-methoxyphenyl)-1-benzothiophene-2-carboxylic acid
|
|
IT202400000246A1
(it)
|
2024-01-09 |
2025-07-09 |
Procos Spa |
Processo per la preparazione di sparsentan
|
|
LT7101B
(lt)
|
2024-01-16 |
2024-10-25 |
Steponavičius Petras |
Organinės trąšos sapropelio pagrindu ir jų gamybos būdas, panaudojant susmulkintus šiaudus, aukštapelkines durpes ir hidrogelį
|
|
TW202539633A
(zh)
|
2024-02-01 |
2025-10-16 |
美商輝瑞股份有限公司 |
葡萄糖依賴性促胰島素多肽受體拮抗劑及其用途
|
|
US20250326741A1
(en)
|
2024-04-22 |
2025-10-23 |
Pfizer Inc. |
Glucose-dependent insulinotropic polypeptide receptor antagonists and uses thereof
|
|
WO2026013531A1
(en)
|
2024-07-10 |
2026-01-15 |
Pfizer Inc. |
Spiro[2.5]octane compounds
|
|
WO2026033382A1
(en)
|
2024-08-07 |
2026-02-12 |
Pfizer Inc. |
Heterocyclic glp-1r modulators
|
|
WO2026042018A1
(en)
|
2024-08-21 |
2026-02-26 |
Pfizer Inc. |
4-{4-[(1-{[4-(propan-2-yl)phenyl]carbamoyl)-d-prolyl)amino]cyclohexyl}benzoic acid derivatives as gipr antagonists for the treatment of diabetes
|
|
WO2026078617A1
(en)
|
2024-10-11 |
2026-04-16 |
Pfizer Inc. |
Glucose-dependent insulinotropic polypeptide receptor antagonists and uses thereof
|
|
WO2026078671A1
(en)
|
2024-10-13 |
2026-04-16 |
Pfizer Inc. |
Heterocyclic compounds as glucose-dependent insulinotropic polypeptide receptor antagonists
|
|
WO2026078670A1
(en)
|
2024-10-13 |
2026-04-16 |
Pfizer Inc. |
Heterocyclic derivatives as glucose-dependent insulinotropic polypeptide receptor antagonists
|
|
WO2026078674A1
(en)
|
2024-10-13 |
2026-04-16 |
Pfizer Inc. |
Heterocyclic derivatives as glucose-dependent insulinotropic polypeptide receptor antagonists and uses thereof
|
|
WO2026078673A1
(en)
|
2024-10-13 |
2026-04-16 |
Pfizer Inc. |
Glucose-dependent insulinotropic polypeptide receptor antagonists and uses thereof
|
|
WO2026078672A1
(en)
|
2024-10-13 |
2026-04-16 |
Pfizer Inc. |
Glucose-dependent insulinotropic polypeptide receptor antagonists and uses thereof
|