NO20011270L - Tricykliske <delta>3-piperidiner som <alfa>2-antagonister - Google Patents

Tricykliske <delta>3-piperidiner som <alfa>2-antagonister

Info

Publication number: NO20011270L
Authority: NO; Norway
Prior art keywords: parta; piperidines; alfa; tricyclic; antagonists
Prior art date: 1998-10-06

Application number

NO20011270A

Other languages

English (en)

Other versions

NO20011270D0 (no

Inventor

Ludo Edmond Josephine Kennis

Frans Maria Alfons Van Keybus

Josephus Carolus Mertens

Original Assignee

Janssen Pharmaceutica Nv

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1998-10-06

Filing date

2001-03-13

Publication date

2001-03-13

2001-03-13 Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv

2001-03-13 Publication of NO20011270L publication Critical patent/NO20011270L/no

2001-03-13 Publication of NO20011270D0 publication Critical patent/NO20011270D0/no

Links

239000005557 antagonist Substances 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Medicinal Chemistry (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Diabetes (AREA)
Endocrinology (AREA)
Reproductive Health (AREA)
Hematology (AREA)
Psychiatry (AREA)
Obesity (AREA)
Pain & Pain Management (AREA)
Hospice & Palliative Care (AREA)
Psychology (AREA)
Ophthalmology & Optometry (AREA)
Emergency Medicine (AREA)
Gynecology & Obstetrics (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Hydrogenated Pyridines (AREA)

NO20011270A 1998-10-06 2001-03-13 Tricykliske <delta>3-piperidiner som <alfa>2-antagonister NO20011270D0 (no)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
EP98203370		1998-10-06
PCT/EP1999/007419 WO2000020421A2 (en)	1998-10-06	1999-10-01	TRICYCLIC Δ3-PIPERIDINES AS α2-ANTAGONISTS

Publications (2)

Publication Number	Publication Date
NO20011270L true NO20011270L (no)	2001-03-13
NO20011270D0 NO20011270D0 (no)	2001-03-13

Family

ID=8234191

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO20011270A NO20011270D0 (no)	1998-10-06	2001-03-13	Tricykliske <delta>3-piperidiner som <alfa>2-antagonister

Country Status (30)

Country	Link
US (1)	US6495555B1 (no)
EP (1)	EP1119571B1 (no)
JP (1)	JP4590101B2 (no)
KR (1)	KR20010071843A (no)
CN (1)	CN1131230C (no)
AR (1)	AR024216A1 (no)
AT (1)	ATE232869T1 (no)
AU (1)	AU760502B2 (no)
BG (1)	BG64872B1 (no)
BR (1)	BR9913507A (no)
CA (1)	CA2345622C (no)
CZ (1)	CZ20011104A3 (no)
DE (1)	DE69905478T2 (no)
DK (1)	DK1119571T3 (no)
EE (1)	EE04770B1 (no)
ES (1)	ES2193751T3 (no)
HU (1)	HUP0104002A3 (no)
ID (1)	ID28032A (no)
IL (1)	IL142443A0 (no)
NO (1)	NO20011270D0 (no)
NZ (1)	NZ510115A (no)
PL (1)	PL347894A1 (no)
PT (1)	PT1119571E (no)
RU (1)	RU2230744C2 (no)
SI (1)	SI1119571T1 (no)
SK (1)	SK285585B6 (no)
TR (1)	TR200100952T2 (no)
TW (1)	TWI248441B (no)
UA (1)	UA69420C2 (no)
WO (1)	WO2000020421A2 (no)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JP4590102B2 (ja) *	1998-10-06	2010-12-01	ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ	医薬としての三環性δ３−ピペリジン類
AU2003219199A1 (en) *	2002-04-03	2003-10-13	Orion Corporation	Use of an alfa2-adrenoreceptor antagonist for cns-related diseases
AU2005233456A1 (en)	2004-04-12	2005-10-27	Taisho Pharmaceutical Co., Ltd.	Cyclic amine compound
US20060035939A1 (en) *	2004-07-14	2006-02-16	Japan Tobacco Inc.	3-Aminobenzamide compounds and inhibitors of vanilloid receptor subtype 1 (VR1) activity
WO2006006741A1 (ja) *	2004-07-15	2006-01-19	Japan Tobacco Inc.	縮合ベンズアミド化合物及びバニロイド受容体１型(ｖｒ１)活性阻害剤
US7906508B2 (en) *	2005-12-28	2011-03-15	Japan Tobacco Inc.	3,4-dihydrobenzoxazine compounds and inhibitors of vanilloid receptor subtype 1 (VRI) activity
NZ596137A (en)	2009-05-14	2013-08-30	Janssen Pharmaceutica Nv	Compounds with two fused bicyclic heteroaryl moieties as modulators of leukotriene a4 hydrolase
WO2015091414A2 (de)	2013-12-19	2015-06-25	Bayer Pharma Aktiengesellschaft	Substituierte piperidinyl-tetrahydrochinoline
EP3083610A1 (de)	2013-12-19	2016-10-26	Bayer Pharma Aktiengesellschaft	Substituierte bipiperidinyl-derivate als adrenrezeptor alpha 2c antagonisten
KR20160098424A (ko) *	2013-12-19	2016-08-18	바이엘 파마 악티엔게젤샤프트	치환된 피페리디닐-테트라히드로퀴놀린
CN114276359B (zh) *	2022-01-05	2023-05-05	浙江大学	一种1,2,3,4-四氢苯并[4,5]呋喃[2,3-c]吡啶衍生物的制备方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
SU926914A1 (ru) *	1980-05-26	1992-04-23	Научно-исследовательский институт фармакологии АМН СССР	Производные 1,2,3,4-тетрагидробензофуро[3,2-с]-пиридина или хлоргидрат, обладающие р дом свойств анальгетиков и антагонистов морфина
DE3522959A1 (de) *	1985-06-27	1987-01-08	Merck Patent Gmbh	Indolderivate
US4673680A (en) *	1985-09-18	1987-06-16	Pendleton Robert G	α2 -adrenergic receptor antagonists as modifiers of gastrointestinal motility
EP0339959A3 (en) *	1988-04-27	1991-03-20	Glaxo Group Limited	Lactam derivatives
US4971974A (en)	1988-06-16	1990-11-20	Neurex Corporation	Benzothiophenes as appetite suppressants
US5100891A (en) *	1991-01-18	1992-03-31	Hoechst-Roussel Pharmaceuticals Inc.	Substituted 1,2,3,4-tetrahydrocyclopent[b]indoles, 1,2,3,3a,4,8a-hexahydrocyclopent[B]indoles and related compounds
ES2168682T3 (es) *	1996-12-06	2002-06-16	Abbott Lab	Compuestos alfa-1 adrenergicos a base de benzopiranopirrol y de benzopiranopiridina.
ES2238778T3 (es)	1997-12-25	2005-09-01	Meiji Seika Kaisha, Ltd.	Derivados de tetrahidrobenzoindol.
JP4590102B2 (ja) *	1998-10-06	2010-12-01	ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ	医薬としての三環性δ３−ピペリジン類

1999
- 1999-01-10 UA UA2001031999A patent/UA69420C2/uk unknown
- 1999-10-01 CZ CZ20011104A patent/CZ20011104A3/cs unknown
- 1999-10-01 CN CN99811682A patent/CN1131230C/zh not_active Expired - Fee Related
- 1999-10-01 SI SI9930264T patent/SI1119571T1/xx unknown
- 1999-10-01 CA CA002345622A patent/CA2345622C/en not_active Expired - Fee Related
- 1999-10-01 IL IL14244399A patent/IL142443A0/xx not_active IP Right Cessation
- 1999-10-01 RU RU2001111812/04A patent/RU2230744C2/ru not_active IP Right Cessation
- 1999-10-01 AU AU63341/99A patent/AU760502B2/en not_active Ceased
- 1999-10-01 ID IDW20010780A patent/ID28032A/id unknown
- 1999-10-01 NZ NZ510115A patent/NZ510115A/xx unknown
- 1999-10-01 PT PT99950627T patent/PT1119571E/pt unknown
- 1999-10-01 EE EEP200100209A patent/EE04770B1/xx not_active IP Right Cessation
- 1999-10-01 DE DE69905478T patent/DE69905478T2/de not_active Expired - Lifetime
- 1999-10-01 TR TR2001/00952T patent/TR200100952T2/xx unknown
- 1999-10-01 AT AT99950627T patent/ATE232869T1/de not_active IP Right Cessation
- 1999-10-01 DK DK99950627T patent/DK1119571T3/da active
- 1999-10-01 US US09/806,547 patent/US6495555B1/en not_active Expired - Lifetime
- 1999-10-01 PL PL99347894A patent/PL347894A1/xx not_active Application Discontinuation
- 1999-10-01 BR BR9913507-8A patent/BR9913507A/pt not_active IP Right Cessation
- 1999-10-01 EP EP99950627A patent/EP1119571B1/en not_active Expired - Lifetime
- 1999-10-01 HU HU0104002A patent/HUP0104002A3/hu unknown
- 1999-10-01 TW TW088116898A patent/TWI248441B/zh not_active IP Right Cessation
- 1999-10-01 SK SK432-2001A patent/SK285585B6/sk unknown
- 1999-10-01 ES ES99950627T patent/ES2193751T3/es not_active Expired - Lifetime
- 1999-10-01 JP JP2000574533A patent/JP4590101B2/ja not_active Expired - Fee Related
- 1999-10-01 KR KR1020017000442A patent/KR20010071843A/ko not_active Ceased
- 1999-10-01 WO PCT/EP1999/007419 patent/WO2000020421A2/en not_active Ceased
- 1999-10-05 AR ARP990105038A patent/AR024216A1/es not_active Application Discontinuation
2001
- 2001-03-12 BG BG105332A patent/BG64872B1/bg unknown
- 2001-03-13 NO NO20011270A patent/NO20011270D0/no not_active Application Discontinuation

Also Published As

Publication number	Publication date
ES2193751T3 (es)	2003-11-01
EE04770B1 (et)	2007-02-15
JP2002526545A (ja)	2002-08-20
EE200100209A (et)	2002-06-17
AU760502B2 (en)	2003-05-15
CZ20011104A3 (cs)	2001-12-12
BG105332A (en)	2001-11-30
SK285585B6 (sk)	2007-04-05
AR024216A1 (es)	2002-09-25
NO20011270D0 (no)	2001-03-13
WO2000020421A2 (en)	2000-04-13
CA2345622C (en)	2007-12-04
PL347894A1 (en)	2002-04-22
RU2230744C2 (ru)	2004-06-20
CN1332744A (zh)	2002-01-23
DE69905478T2 (de)	2004-03-18
DE69905478D1 (de)	2003-03-27
PT1119571E (pt)	2003-06-30
TR200100952T2 (tr)	2001-10-22
SI1119571T1 (en)	2003-08-31
TWI248441B (en)	2006-02-01
KR20010071843A (ko)	2001-07-31
CN1131230C (zh)	2003-12-17
ID28032A (id)	2001-05-03
EP1119571A2 (en)	2001-08-01
NZ510115A (en)	2002-11-26
ATE232869T1 (de)	2003-03-15
IL142443A0 (en)	2002-03-10
HUP0104002A2 (hu)	2002-03-28
BG64872B1 (bg)	2006-07-31
AU6334199A (en)	2000-04-26
CA2345622A1 (en)	2000-04-13
US6495555B1 (en)	2002-12-17
HK1038010A1 (en)	2002-03-01
EP1119571B1 (en)	2003-02-19
WO2000020421A3 (en)	2000-08-03
HUP0104002A3 (en)	2003-12-29
DK1119571T3 (da)	2003-05-26
JP4590101B2 (ja)	2010-12-01
BR9913507A (pt)	2001-06-05
UA69420C2 (uk)	2004-09-15
SK4322001A3 (en)	2002-01-07

Legal Events

Date	Code	Title	Description
2008-05-26	FC2A	Withdrawal, rejection or dismissal of laid open patent application

Publication	Publication Date	Title
DE19983812T1 (de)	2002-01-10	Verriegelungsspannfutter
NO20003706L (no)	2000-09-14	Ny tricyklisk forbindelse
LTPA2009006I1 (lt)	2022-03-10	Trombopoetino junginiai
ATE229954T1 (de)	2003-01-15	Betacarbolinverbindungen
ID28266A (id)	2001-05-10	Senyawa-senyawa amidin
FI4209U1 (fi)	1999-11-10	Uusia yhdisteitä
NO991821D0 (no)	1999-04-16	Substituerte tricykliske forbindelser
DE69908845D1 (de)	2003-07-24	Fotoresistzusammensetzung
ID27004A (id)	2001-02-22	Senyawa-senyawa kalsilitik
DE69919255D1 (de)	2004-09-16	Graviervorrichtung
NO20011270D0 (no)	2001-03-13	Tricykliske <delta>3-piperidiner som <alfa>2-antagonister
NO991823L (no)	1999-10-18	Substituerte tricykliske forbindelser
NO20011402D0 (no)	2001-03-20	Tricykliske <delta>3-piperidiner som farmasøytiske midler
NO20011309D0 (no)	2001-03-15	Benzotieno [3,2-c]pyridiner som<alfa>2-antagonister
DE69908923D1 (de)	2003-07-24	1,3,4-thiadiazolylazofarbstoffe-enthaltende tintenzusammensetzungen
FI3438U1 (fi)	1998-06-26	Liukuestemekanismi
FI3524U1 (fi)	1998-08-13	Yhdistelmäkoura
SE9800509D0 (sv)	1998-02-20	New Compounds
SE9800977D0 (sv)	1998-03-24	New compounds
SE9803747D0 (sv)	1998-11-03	New compounds
SE9800834D0 (sv)	1998-03-13	New Compounds
SE9801099D0 (sv)	1998-03-30	New compounds
SE9800510D0 (sv)	1998-02-20	New Compounds
SE9803746D0 (sv)	1998-11-03	New compounds
SE9800508D0 (sv)	1998-02-20	New Compounds