ID28032A - TRISIKLIK PIPERIDIN-Δ3-SEBAGAI ANTAGONIS-α2 - Google Patents

TRISIKLIK PIPERIDIN-Δ3-SEBAGAI ANTAGONIS-α2

Info

Publication number: ID28032A
Authority: ID; Indonesia
Prior art keywords: triciclic; antagonis; piperidin
Prior art date: 1998-10-06

Application number

IDW20010780A

Other languages

English (en)

Inventor

Ludo E J Kennis

Frans M A Van Den Keybus

Josephus C Mertens

Original Assignee

Janssen Pharmaceutica Nv

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1998-10-06

Filing date

1999-10-01

Publication date

2001-05-03

1999-10-01 Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv

2001-05-03 Publication of ID28032A publication Critical patent/ID28032A/id

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
General Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Diabetes (AREA)
Endocrinology (AREA)
Reproductive Health (AREA)
Psychiatry (AREA)
Hematology (AREA)
Obesity (AREA)
Emergency Medicine (AREA)
Gynecology & Obstetrics (AREA)
Ophthalmology & Optometry (AREA)
Hospice & Palliative Care (AREA)
Psychology (AREA)
Pain & Pain Management (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Hydrogenated Pyridines (AREA)

IDW20010780A 1998-10-06 1999-10-01 TRISIKLIK PIPERIDIN-Δ3-SEBAGAI ANTAGONIS-α2 ID28032A (id)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
EP98203370		1998-10-06

Publications (1)

Publication Number	Publication Date
ID28032A true ID28032A (id)	2001-05-03

Family

ID=8234191

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IDW20010780A ID28032A (id)	1998-10-06	1999-10-01	TRISIKLIK PIPERIDIN-Δ3-SEBAGAI ANTAGONIS-α2

Country Status (30)

Country	Link
US (1)	US6495555B1 (id)
EP (1)	EP1119571B1 (id)
JP (1)	JP4590101B2 (id)
KR (1)	KR20010071843A (id)
CN (1)	CN1131230C (id)
AR (1)	AR024216A1 (id)
AT (1)	ATE232869T1 (id)
AU (1)	AU760502B2 (id)
BG (1)	BG64872B1 (id)
BR (1)	BR9913507A (id)
CA (1)	CA2345622C (id)
CZ (1)	CZ20011104A3 (id)
DE (1)	DE69905478T2 (id)
DK (1)	DK1119571T3 (id)
EE (1)	EE04770B1 (id)
ES (1)	ES2193751T3 (id)
HU (1)	HUP0104002A3 (id)
ID (1)	ID28032A (id)
IL (1)	IL142443A0 (id)
NO (1)	NO20011270D0 (id)
NZ (1)	NZ510115A (id)
PL (1)	PL347894A1 (id)
PT (1)	PT1119571E (id)
RU (1)	RU2230744C2 (id)
SI (1)	SI1119571T1 (id)
SK (1)	SK285585B6 (id)
TR (1)	TR200100952T2 (id)
TW (1)	TWI248441B (id)
UA (1)	UA69420C2 (id)
WO (1)	WO2000020421A2 (id)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ATE269337T1 (de) *	1998-10-06	2004-07-15	Janssen Pharmaceutica Nv	Trizyclische delta3-pyridine als arzneimittel
US20050203100A1 (en) *	2002-04-03	2005-09-15	Jukka Sallinen	Use of an alfa2-adrenoreceptor antagonist for cns-related diseases
JP4816453B2 (ja)	2004-04-12	2011-11-16	大正製薬株式会社	環状アミン化合物
WO2006006740A1 (ja) *	2004-07-14	2006-01-19	Japan Tobacco Inc.	３−アミノベンズアミド化合物及びバニロイド受容体１型(ｖｒ１)活性阻害剤
KR101042490B1 (ko) *	2004-07-15	2011-06-16	니뽄 다바코 산교 가부시키가이샤	축합 벤즈아미드 화합물 및 바닐로이드 수용체 1형(ｖｒ1)활성 저해제
US7906508B2 (en) *	2005-12-28	2011-03-15	Japan Tobacco Inc.	3,4-dihydrobenzoxazine compounds and inhibitors of vanilloid receptor subtype 1 (VRI) activity
MX2011012190A (es)	2009-05-14	2011-12-08	Janssen Pharmaceutica Nv	Compuestos con dos porciones de heteroarilo biciclico fusionado como moduladores de la leucotrieno a4 hidrolasa.
CA2934134A1 (en)	2013-12-19	2015-06-25	Bayer Pharma Aktiengesellschaft	Substituted bipiperidinyl derivatives as adrenoreceptor alpha 2c antagonists
JP2017501164A (ja) *	2013-12-19	2017-01-12	バイエルファーマアクチエンゲゼルシャフト	置換されたピペリジニルテトラヒドロキノリン類
SG11201604978QA (en)	2013-12-19	2016-07-28	Bayer Pharma AG	Substituted piperidinyl-tetrahydroquinolines and their use as alpha-2c adrenoreceptor antagonists
CN114276359B (zh) *	2022-01-05	2023-05-05	浙江大学	一种1,2,3,4-四氢苯并[4,5]呋喃[2,3-c]吡啶衍生物的制备方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
SU926914A1 (ru) *	1980-05-26	1992-04-23	Научно-исследовательский институт фармакологии АМН СССР	Производные 1,2,3,4-тетрагидробензофуро[3,2-с]-пиридина или хлоргидрат, обладающие р дом свойств анальгетиков и антагонистов морфина
DE3522959A1 (de) *	1985-06-27	1987-01-08	Merck Patent Gmbh	Indolderivate
US4673680A (en) *	1985-09-18	1987-06-16	Pendleton Robert G	α2 -adrenergic receptor antagonists as modifiers of gastrointestinal motility
EP0339959A3 (en) *	1988-04-27	1991-03-20	Glaxo Group Limited	Lactam derivatives
US4971974A (en) *	1988-06-16	1990-11-20	Neurex Corporation	Benzothiophenes as appetite suppressants
US5100891A (en) *	1991-01-18	1992-03-31	Hoechst-Roussel Pharmaceuticals Inc.	Substituted 1,2,3,4-tetrahydrocyclopent[b]indoles, 1,2,3,3a,4,8a-hexahydrocyclopent[B]indoles and related compounds
WO1998024791A1 (en) *	1996-12-06	1998-06-11	Abbott Laboratories	Benzopyranopyrrole and benzopyranopyridine alpha-1 adrenergic compounds
WO1999033804A1 (en) *	1997-12-25	1999-07-08	Meiji Seika Kaisha, Ltd.	Tetrahydrobenzindole derivatives
ATE269337T1 (de) *	1998-10-06	2004-07-15	Janssen Pharmaceutica Nv	Trizyclische delta3-pyridine als arzneimittel

1999
- 1999-01-10 UA UA2001031999A patent/UA69420C2/uk unknown
- 1999-10-01 HU HU0104002A patent/HUP0104002A3/hu unknown
- 1999-10-01 SI SI9930264T patent/SI1119571T1/xx unknown
- 1999-10-01 NZ NZ510115A patent/NZ510115A/xx unknown
- 1999-10-01 ES ES99950627T patent/ES2193751T3/es not_active Expired - Lifetime
- 1999-10-01 BR BR9913507-8A patent/BR9913507A/pt not_active IP Right Cessation
- 1999-10-01 EE EEP200100209A patent/EE04770B1/xx not_active IP Right Cessation
- 1999-10-01 DK DK99950627T patent/DK1119571T3/da active
- 1999-10-01 AT AT99950627T patent/ATE232869T1/de not_active IP Right Cessation
- 1999-10-01 PL PL99347894A patent/PL347894A1/xx not_active Application Discontinuation
- 1999-10-01 CZ CZ20011104A patent/CZ20011104A3/cs unknown
- 1999-10-01 CA CA002345622A patent/CA2345622C/en not_active Expired - Fee Related
- 1999-10-01 AU AU63341/99A patent/AU760502B2/en not_active Ceased
- 1999-10-01 US US09/806,547 patent/US6495555B1/en not_active Expired - Lifetime
- 1999-10-01 DE DE69905478T patent/DE69905478T2/de not_active Expired - Lifetime
- 1999-10-01 ID IDW20010780A patent/ID28032A/id unknown
- 1999-10-01 SK SK432-2001A patent/SK285585B6/sk unknown
- 1999-10-01 PT PT99950627T patent/PT1119571E/pt unknown
- 1999-10-01 TR TR2001/00952T patent/TR200100952T2/xx unknown
- 1999-10-01 IL IL14244399A patent/IL142443A0/xx not_active IP Right Cessation
- 1999-10-01 KR KR1020017000442A patent/KR20010071843A/ko not_active Ceased
- 1999-10-01 JP JP2000574533A patent/JP4590101B2/ja not_active Expired - Fee Related
- 1999-10-01 TW TW088116898A patent/TWI248441B/zh not_active IP Right Cessation
- 1999-10-01 WO PCT/EP1999/007419 patent/WO2000020421A2/en not_active Ceased
- 1999-10-01 RU RU2001111812/04A patent/RU2230744C2/ru not_active IP Right Cessation
- 1999-10-01 EP EP99950627A patent/EP1119571B1/en not_active Expired - Lifetime
- 1999-10-01 CN CN99811682A patent/CN1131230C/zh not_active Expired - Fee Related
- 1999-10-05 AR ARP990105038A patent/AR024216A1/es not_active Application Discontinuation
2001
- 2001-03-12 BG BG105332A patent/BG64872B1/bg unknown
- 2001-03-13 NO NO20011270A patent/NO20011270D0/no not_active Application Discontinuation

Also Published As

Publication number	Publication date
ES2193751T3 (es)	2003-11-01
EE200100209A (et)	2002-06-17
SK285585B6 (sk)	2007-04-05
NO20011270L (no)	2001-03-13
DK1119571T3 (da)	2003-05-26
CA2345622A1 (en)	2000-04-13
AU6334199A (en)	2000-04-26
RU2230744C2 (ru)	2004-06-20
HUP0104002A3 (en)	2003-12-29
CZ20011104A3 (cs)	2001-12-12
JP2002526545A (ja)	2002-08-20
NZ510115A (en)	2002-11-26
PL347894A1 (en)	2002-04-22
EP1119571B1 (en)	2003-02-19
SI1119571T1 (en)	2003-08-31
AR024216A1 (es)	2002-09-25
IL142443A0 (en)	2002-03-10
JP4590101B2 (ja)	2010-12-01
ATE232869T1 (de)	2003-03-15
HK1038010A1 (en)	2002-03-01
WO2000020421A3 (en)	2000-08-03
SK4322001A3 (en)	2002-01-07
PT1119571E (pt)	2003-06-30
TR200100952T2 (tr)	2001-10-22
TWI248441B (en)	2006-02-01
CA2345622C (en)	2007-12-04
KR20010071843A (ko)	2001-07-31
US6495555B1 (en)	2002-12-17
WO2000020421A2 (en)	2000-04-13
NO20011270D0 (no)	2001-03-13
BG105332A (en)	2001-11-30
DE69905478D1 (de)	2003-03-27
DE69905478T2 (de)	2004-03-18
EP1119571A2 (en)	2001-08-01
CN1131230C (zh)	2003-12-17
EE04770B1 (et)	2007-02-15
CN1332744A (zh)	2002-01-23
UA69420C2 (uk)	2004-09-15
BR9913507A (pt)	2001-06-05
BG64872B1 (bg)	2006-07-31
AU760502B2 (en)	2003-05-15
HUP0104002A2 (hu)	2002-03-28

Publication	Publication Date	Title
ID27092A (id)	2001-03-01	Pembuatan ftalat anhidrida
CY2012029I2 (el)	2015-08-05	Nεα μορφη της 5-ομεπραζολης
IS2325B (is)	2007-12-15	Örgerðar samsetningar epleróns
DE59914158D1 (de)	2007-03-08	Metallocenmonohalogenide
ATE341990T1 (de)	2006-11-15	Sigmidoskop
DE59912371D1 (de)	2005-09-08	Gleitschalungsfertiger
DE69808145D1 (de)	2002-10-24	Tintenbehälternachfüllsystem
DE59902874D1 (de)	2002-10-31	Buchsenkontakt
DE59901560D1 (de)	2002-07-04	Retrograder tibianagel
DE59907306D1 (de)	2003-11-13	Fadenchangierung
DE59906931D1 (de)	2003-10-16	Exzenterzahnradgetriebe
DE59911683D1 (de)	2005-04-07	Fahrzeugschliessanlage
DE69811890D1 (de)	2003-04-10	Einzellenkalorimeter
ATE262513T1 (de)	2004-04-15	Benzoylpyridazine
DE59903966D1 (de)	2003-02-13	Exzenterzahnradgetriebe
DE59913393D1 (de)	2006-06-08	Fadenchangierung
DE59908769D1 (de)	2004-04-08	N-arylsulfonyl-aminosäure-omega-amide
DE59903106D1 (de)	2002-11-21	Tripode-gleichlaufdrehgelenk
DE59908057D1 (de)	2004-01-29	Underdruckhandhabungseinrichung
DE69809804D1 (de)	2003-01-09	Notlaufgeländereifen
DE59901046D1 (de)	2002-05-02	Methylcyclotetradec-5-en-1-one
DE59808995D1 (de)	2003-08-14	Endomikroskopsystem
DE59807217D1 (de)	2003-03-20	Nadellager
DE19842103B4 (de)	2005-03-10	Stanznietzuführung
DE69938967D1 (de)	2008-08-07	En