NO20014758L - C(7)-heterosubstituerte acetattaxaner som antitumormidler - Google Patents
C(7)-heterosubstituerte acetattaxaner som antitumormidlerInfo
- Publication number
- NO20014758L NO20014758L NO20014758A NO20014758A NO20014758L NO 20014758 L NO20014758 L NO 20014758L NO 20014758 A NO20014758 A NO 20014758A NO 20014758 A NO20014758 A NO 20014758A NO 20014758 L NO20014758 L NO 20014758L
- Authority
- NO
- Norway
- Prior art keywords
- antitumor agents
- heterosubstituted acetate
- taxanes
- heterosubstituted
- acetate taxanes
- Prior art date
Links
- 229940123237 Taxane Drugs 0.000 title 1
- 150000001242 acetic acid derivatives Chemical class 0.000 title 1
- 239000002246 antineoplastic agent Substances 0.000 title 1
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical group CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 125000001424 substituent group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
- C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
- C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
- C07D407/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
- C07D407/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Epoxy Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US17967200P | 2000-02-02 | 2000-02-02 | |
| PCT/US2001/003600 WO2001057029A1 (fr) | 2000-02-02 | 2001-02-02 | Taxanes d'acetate c7-heterosubstituees utilisees en tant qu'agents antitumoraux |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| NO20014758D0 NO20014758D0 (no) | 2001-10-01 |
| NO20014758L true NO20014758L (no) | 2001-11-29 |
Family
ID=22657505
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20014758A NO20014758L (no) | 2000-02-02 | 2001-10-01 | C(7)-heterosubstituerte acetattaxaner som antitumormidler |
Country Status (20)
| Country | Link |
|---|---|
| US (3) | US6673833B2 (fr) |
| EP (1) | EP1200424B1 (fr) |
| JP (1) | JP2003522169A (fr) |
| KR (1) | KR20010112393A (fr) |
| CN (1) | CN1362957A (fr) |
| AT (1) | ATE413397T1 (fr) |
| AU (1) | AU776765B2 (fr) |
| BR (1) | BR0104353A (fr) |
| CA (1) | CA2368534A1 (fr) |
| CZ (1) | CZ20013519A3 (fr) |
| DE (1) | DE60136430D1 (fr) |
| HK (1) | HK1047935A1 (fr) |
| HU (1) | HUP0200651A3 (fr) |
| IL (1) | IL145642A0 (fr) |
| MX (1) | MXPA01009922A (fr) |
| NO (1) | NO20014758L (fr) |
| NZ (1) | NZ514411A (fr) |
| PL (1) | PL350328A1 (fr) |
| WO (1) | WO2001057029A1 (fr) |
| ZA (1) | ZA200108063B (fr) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2001057029A1 (fr) * | 2000-02-02 | 2001-08-09 | Florida State University Research Foundation, Inc. | Taxanes d'acetate c7-heterosubstituees utilisees en tant qu'agents antitumoraux |
| US20040210289A1 (en) * | 2002-03-04 | 2004-10-21 | Xingwu Wang | Novel nanomagnetic particles |
| US7390898B2 (en) | 2002-08-02 | 2008-06-24 | Immunogen Inc. | Cytotoxic agents containing novel potent taxanes and their therapeutic use |
| BR0313197A (pt) | 2002-08-02 | 2005-08-09 | Immunogen Inc | Agentes citotóxicos contendo potentes taxanos e seu uso terapêutico |
| US20070149496A1 (en) * | 2003-10-31 | 2007-06-28 | Jack Tuszynski | Water-soluble compound |
| EP1737444A4 (fr) * | 2004-03-05 | 2008-05-21 | Univ Florida State Res Found | Taxanes a substitution de c7 lactyloxy- |
| US20050249667A1 (en) * | 2004-03-24 | 2005-11-10 | Tuszynski Jack A | Process for treating a biological organism |
| CN1712399B (zh) * | 2004-06-24 | 2010-08-11 | 中国医学科学院药物研究所 | 紫杉醇和免疫增强剂胞壁酰二肽共轭物的制备及用途 |
| US20080081067A1 (en) * | 2006-10-03 | 2008-04-03 | Gupta Manishkumar | Sustained release pharmaceutical compositions of venlafaxine and process for preparation thereof |
| EP3239139B1 (fr) | 2010-05-27 | 2020-10-28 | Ningbo Combireg Pharmaceutical Technology Co. Ltd | Synthèse chimique et effets antitumoraux et antimétastatiques d'un conjugué à double fonction |
Family Cites Families (39)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4879929A (en) * | 1988-06-06 | 1989-11-14 | Roth Alfred C | Tapper/threader assembly |
| US4950790A (en) * | 1988-11-14 | 1990-08-21 | Air Products And Chemicals, Inc. | Volatile fluorinated β-ketoimines and associated metal complexes |
| US4960790A (en) | 1989-03-09 | 1990-10-02 | University Of Kansas | Derivatives of taxol, pharmaceutical compositions thereof and methods for the preparation thereof |
| US5175315A (en) | 1989-05-31 | 1992-12-29 | Florida State University | Method for preparation of taxol using β-lactam |
| US5243253A (en) * | 1991-07-30 | 1993-09-07 | Thomson Consumer Electronics, Inc. | Color picture tube having shadow mask with improved tie bar grading |
| US5430160A (en) | 1991-09-23 | 1995-07-04 | Florida State University | Preparation of substituted isoserine esters using β-lactams and metal or ammonium alkoxides |
| US5250683A (en) | 1991-09-23 | 1993-10-05 | Florida State University | Certain substituted taxanes and pharmaceutical compositions containing them |
| US5283253A (en) | 1991-09-23 | 1994-02-01 | Florida State University | Furyl or thienyl carbonyl substituted taxanes and pharmaceutical compositions containing them |
| US5350866A (en) | 1991-09-23 | 1994-09-27 | Bristol-Myers Squibb Company | 10-desacetoxytaxol derivatives |
| US5227400A (en) | 1991-09-23 | 1993-07-13 | Florida State University | Furyl and thienyl substituted taxanes and pharmaceutical compositions containing them |
| US5714513A (en) | 1991-09-23 | 1998-02-03 | Florida State University | C10 taxane derivatives and pharmaceutical compositions |
| US5243045A (en) | 1991-09-23 | 1993-09-07 | Florida State University | Certain alkoxy substituted taxanes and pharmaceutical compositions containing them |
| US5721268A (en) | 1991-09-23 | 1998-02-24 | Florida State University | C7 taxane derivatives and pharmaceutical compositions containing them |
| DK0552041T3 (da) | 1992-01-15 | 2000-10-09 | Squibb & Sons Inc | Enzymatiske fremgangsmåder til spaltning af enantiomerblandinger af forbindelser, der er nyttige som mellemprodukter ved fr |
| DE4302686C2 (de) * | 1992-02-05 | 1994-12-15 | Bierther Hans Dietmar | Hochleistungsventil |
| FR2687150B1 (fr) | 1992-02-07 | 1995-04-28 | Rhone Poulenc Rorer Sa | Procede de preparation de derives du taxane. |
| US5272171A (en) | 1992-02-13 | 1993-12-21 | Bristol-Myers Squibb Company | Phosphonooxy and carbonate derivatives of taxol |
| US5939561A (en) | 1992-03-10 | 1999-08-17 | Rhone-Poulence Rorer S.A. | Process for the preparation of β-phenylisoserine and β-lactam and their analogues |
| US5200534A (en) | 1992-03-13 | 1993-04-06 | University Of Florida | Process for the preparation of taxol and 10-deacetyltaxol |
| IL108443A0 (en) * | 1993-01-29 | 1994-04-12 | Univ Florida State | C7 taxane derivatives and pharmaceutical compositions containing them |
| US5703247A (en) | 1993-03-11 | 1997-12-30 | Virginia Tech Intellectual Properties, Inc. | 2-Debenzoyl-2-acyl taxol derivatives and methods for making same |
| DK0690867T3 (da) * | 1993-03-22 | 2003-06-10 | Univ Florida State | Taxaner med furyl- eller thienylsubstitueret sidekæde |
| US5350253A (en) * | 1993-03-24 | 1994-09-27 | John Cunningham | Method for supporting distribution means |
| IL109926A (en) | 1993-06-15 | 2000-02-29 | Bristol Myers Squibb Co | Methods for the preparation of taxanes and microorganisms and enzymes utilized therein |
| TW397866B (en) | 1993-07-14 | 2000-07-11 | Bristol Myers Squibb Co | Enzymatic processes for the resolution of enantiomeric mixtures of compounds useful as intermediates in the preparation of taxanes |
| EP0788493A1 (fr) * | 1994-10-28 | 1997-08-13 | The Research Foundation Of State University Of New York | Derives taxoides, leur preparation et leur utilisation en tant qu'agents antitumoraux |
| US5780653A (en) | 1995-06-07 | 1998-07-14 | Vivorx Pharmaceuticals, Inc. | Nitrophenyl, 10-deacetylated substituted taxol derivatives as dual functional cytotoxic/radiosensitizers |
| WO1997009979A1 (fr) | 1995-09-13 | 1997-03-20 | Florida State University | Taxanes a effet radiosensibilisant et leurs preparations pharmaceutiques |
| US5767297A (en) | 1997-02-05 | 1998-06-16 | Ensuiko Sugar Refining Co., Ltd. | Taxoid derivative and method of producing thereof |
| JP3786462B2 (ja) | 1996-03-07 | 2006-06-14 | 塩水港精糖株式会社 | タキソイドの配糖化誘導体およびその製造方法 |
| AU724499B2 (en) | 1996-05-06 | 2000-09-21 | Florida State University | 1-deoxy baccatin III, 1-deoxy taxol and 1-deoxy taxol analogs and method for the preparation thereof |
| US5780683A (en) * | 1996-09-11 | 1998-07-14 | Abb Lummus Global Inc. | Cyclohexane oxidation |
| US5811452A (en) | 1997-01-08 | 1998-09-22 | The Research Foundation Of State University Of New York | Taxoid reversal agents for drug-resistance in cancer chemotherapy and pharmaceutical compositions thereof |
| US5912264A (en) | 1997-03-03 | 1999-06-15 | Bristol-Myers Squibb Company | 6-halo-or nitrate-substituted paclitaxels |
| CA2206739C (fr) | 1997-06-03 | 2006-10-10 | Ensuiko Sugar Refining Co., Ltd. | Derive de taxoide et methode de production correspondante |
| US7288665B1 (en) | 1997-08-18 | 2007-10-30 | Florida State University | Process for selective derivatization of taxanes |
| US6136988A (en) | 1998-04-10 | 2000-10-24 | Hauser, Inc. | 7-hexanoyltaxol and methods for preparing the same |
| KR20010111580A (ko) | 2000-02-02 | 2001-12-19 | 플로리다 스테이트 유니버시티 리서치 파운데이션, 인크 | 개선된 용해도를 갖는 탁산 제형물 |
| WO2001057029A1 (fr) * | 2000-02-02 | 2001-08-09 | Florida State University Research Foundation, Inc. | Taxanes d'acetate c7-heterosubstituees utilisees en tant qu'agents antitumoraux |
-
2001
- 2001-02-02 WO PCT/US2001/003600 patent/WO2001057029A1/fr not_active Ceased
- 2001-02-02 AU AU34804/01A patent/AU776765B2/en not_active Ceased
- 2001-02-02 IL IL14564201A patent/IL145642A0/xx unknown
- 2001-02-02 JP JP2001557861A patent/JP2003522169A/ja not_active Withdrawn
- 2001-02-02 MX MXPA01009922A patent/MXPA01009922A/es active IP Right Grant
- 2001-02-02 AT AT01906965T patent/ATE413397T1/de not_active IP Right Cessation
- 2001-02-02 HK HK03100169.2A patent/HK1047935A1/zh unknown
- 2001-02-02 EP EP01906965A patent/EP1200424B1/fr not_active Expired - Lifetime
- 2001-02-02 DE DE60136430T patent/DE60136430D1/de not_active Expired - Fee Related
- 2001-02-02 CN CN01800318A patent/CN1362957A/zh active Pending
- 2001-02-02 US US09/776,393 patent/US6673833B2/en not_active Expired - Fee Related
- 2001-02-02 NZ NZ514411A patent/NZ514411A/en unknown
- 2001-02-02 CA CA002368534A patent/CA2368534A1/fr not_active Withdrawn
- 2001-02-02 HU HU0200651A patent/HUP0200651A3/hu unknown
- 2001-02-02 CZ CZ20013519A patent/CZ20013519A3/cs unknown
- 2001-02-02 KR KR1020017012589A patent/KR20010112393A/ko not_active Abandoned
- 2001-02-02 BR BR0104353-6A patent/BR0104353A/pt not_active IP Right Cessation
- 2001-02-02 PL PL01350328A patent/PL350328A1/xx not_active Application Discontinuation
- 2001-10-01 ZA ZA200108063A patent/ZA200108063B/en unknown
- 2001-10-01 NO NO20014758A patent/NO20014758L/no not_active Application Discontinuation
-
2003
- 2003-11-24 US US10/720,826 patent/US6861446B2/en not_active Expired - Fee Related
-
2005
- 2005-02-23 US US11/063,626 patent/US7183312B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| AU776765B2 (en) | 2004-09-23 |
| EP1200424A1 (fr) | 2002-05-02 |
| EP1200424B1 (fr) | 2008-11-05 |
| CN1362957A (zh) | 2002-08-07 |
| MXPA01009922A (es) | 2003-07-14 |
| US7183312B2 (en) | 2007-02-27 |
| HUP0200651A3 (en) | 2002-10-28 |
| WO2001057029A1 (fr) | 2001-08-09 |
| CZ20013519A3 (cs) | 2002-04-17 |
| US6673833B2 (en) | 2004-01-06 |
| CA2368534A1 (fr) | 2001-08-09 |
| DE60136430D1 (de) | 2008-12-18 |
| PL350328A1 (en) | 2002-12-02 |
| AU3480401A (en) | 2001-08-14 |
| ZA200108063B (en) | 2003-12-01 |
| US20020065305A1 (en) | 2002-05-30 |
| US20050143446A1 (en) | 2005-06-30 |
| US20040087547A1 (en) | 2004-05-06 |
| HUP0200651A2 (hu) | 2002-07-29 |
| KR20010112393A (ko) | 2001-12-20 |
| ATE413397T1 (de) | 2008-11-15 |
| IL145642A0 (en) | 2002-06-30 |
| JP2003522169A (ja) | 2003-07-22 |
| BR0104353A (pt) | 2002-04-16 |
| NZ514411A (en) | 2005-02-25 |
| NO20014758D0 (no) | 2001-10-01 |
| HK1047935A1 (zh) | 2003-03-14 |
| US6861446B2 (en) | 2005-03-01 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC2A | Withdrawal, rejection or dismissal of laid open patent application |