NO20020176D0 - Sykliske peptidderivater som inhibitorer for intergrin <alfa>v<beta>6 - Google Patents

Sykliske peptidderivater som inhibitorer for intergrin <alfa>v<beta>6

Info

Publication number
NO20020176D0
NO20020176D0 NO20020176A NO20020176A NO20020176D0 NO 20020176 D0 NO20020176 D0 NO 20020176D0 NO 20020176 A NO20020176 A NO 20020176A NO 20020176 A NO20020176 A NO 20020176A NO 20020176 D0 NO20020176 D0 NO 20020176D0
Authority
NO
Norway
Prior art keywords
intergrin
alfa
inhibitors
beta
cyclic peptide
Prior art date
Application number
NO20020176A
Other languages
English (en)
Norwegian (no)
Other versions
NO20020176L (no
Inventor
Alfred Jonczyk
Beate Diefenbach
Simon Goodman
Ulrich Groth
Gunther Zischinsky
Original Assignee
Merck Patent Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent Gmbh filed Critical Merck Patent Gmbh
Publication of NO20020176L publication Critical patent/NO20020176L/no
Publication of NO20020176D0 publication Critical patent/NO20020176D0/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/64Cyclic peptides containing only normal peptide links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/02Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/06Antipsoriatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Rheumatology (AREA)
  • Molecular Biology (AREA)
  • Dermatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Pain & Pain Management (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
NO20020176A 1999-07-15 2002-01-14 Sykliske peptidderivater som inhibitorer for intergrin <alfa>v<beta>6 NO20020176D0 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19933173A DE19933173A1 (de) 1999-07-15 1999-07-15 Cyclische Peptidderivate als Inhibitoren des Integrins alpha¶v¶beta¶6¶
PCT/EP2000/006188 WO2001005810A2 (fr) 1999-07-15 2000-07-03 DERIVES PEPTIDIQUES CYCLIQUES SERVANT D'INHIBITEURS DE L'INTEGRINE αVβ¿6?

Publications (2)

Publication Number Publication Date
NO20020176L NO20020176L (no) 2002-01-14
NO20020176D0 true NO20020176D0 (no) 2002-01-14

Family

ID=7914891

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20020176A NO20020176D0 (no) 1999-07-15 2002-01-14 Sykliske peptidderivater som inhibitorer for intergrin <alfa>v<beta>6

Country Status (23)

Country Link
EP (2) EP1196433B1 (fr)
JP (1) JP2003505395A (fr)
KR (1) KR20020010928A (fr)
CN (1) CN1361792A (fr)
AR (1) AR024742A1 (fr)
AT (1) ATE340803T1 (fr)
AU (1) AU772782C (fr)
BR (1) BR0012418A (fr)
CA (1) CA2379022A1 (fr)
CZ (1) CZ200226A3 (fr)
DE (2) DE19933173A1 (fr)
DK (1) DK1196433T3 (fr)
ES (1) ES2273703T3 (fr)
HK (1) HK1048641A1 (fr)
HU (1) HUP0201925A3 (fr)
MX (1) MXPA02000465A (fr)
NO (1) NO20020176D0 (fr)
PL (1) PL354363A1 (fr)
PT (1) PT1196433E (fr)
SK (1) SK262002A3 (fr)
TW (1) TWI226890B (fr)
WO (1) WO2001005810A2 (fr)
ZA (1) ZA200201275B (fr)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2002232176B2 (en) * 2001-02-19 2006-06-15 Takara Bio Inc. Cyclic peptide
DE10118550A1 (de) * 2001-04-14 2002-10-17 Merck Patent Gmbh Liganden des Integrins alpha¶nu¶beta¶6¶
US7538084B2 (en) 2003-03-17 2009-05-26 Amr Technology, Inc. Cyclosporins
ATE399542T1 (de) * 2003-10-01 2008-07-15 Merck Patent Gmbh Alfavbeta3 und alfavbeta6 integrin antagonisten als antifibrotische mittel
ES2436170T3 (es) * 2003-12-03 2013-12-27 The Scripps Research Institute Anticuerpos y péptidos específicos de la integrina alfa II beta3
JP2008514701A (ja) 2004-09-29 2008-05-08 エーエムアール テクノロジー インコーポレイテッド シクロスポリンアルキン類似体およびそれらの薬学的使用
JP2008514702A (ja) 2004-09-29 2008-05-08 エーエムアール テクノロジー インコーポレイテッド 新規シクロスポリン類似体およびそれらの薬学的使用
JP2008515886A (ja) 2004-10-06 2008-05-15 エーエムアール テクノロジー インコーポレイテッド シクロスポリンアルキンおよびそれらの医用薬剤としての有用性
GB0520068D0 (en) 2005-10-03 2005-11-09 Cancer Res Technology av peptide ligand
US7696165B2 (en) 2006-03-28 2010-04-13 Albany Molecular Research, Inc. Use of cyclosporin alkyne analogues for preventing or treating viral-induced disorders
US7696166B2 (en) 2006-03-28 2010-04-13 Albany Molecular Research, Inc. Use of cyclosporin alkyne/alkene analogues for preventing or treating viral-induced disorders
EP2064244B1 (fr) 2006-08-03 2019-06-05 MedImmune Limited ANTICORPS DIRIGÉS CONTRE alphaVbeta6 ET LEURS UTILISATIONS
EP2784511A1 (fr) 2013-03-27 2014-10-01 Universität Zürich Intégrine alpha-v-beta6 pour le diagnostic/pronostic du carcinome colorectal
SI3350222T1 (sl) 2015-09-18 2022-01-31 Technische Universitaet Muenchen Ligandi za integrin avbeta6, sinteza in uporaba le-teh
MA52117A (fr) 2017-02-28 2022-04-06 Morphic Therapeutic Inc Inhibiteurs de l'intégrine (alpha-v) (bêta-6)
MX394210B (es) 2017-02-28 2025-03-04 Morphic Therapeutic Inc INHIBIDORES DE INTEGRINA AVß6.
US11332498B2 (en) 2017-03-17 2022-05-17 Technische Universitat Munchen Ligands for integrin αVβ8, synthesis and uses thereof
GB201706472D0 (en) * 2017-04-24 2017-06-07 Cancer Res Tech Ltd Tumour-targeting peptide variants
WO2020047208A1 (fr) 2018-08-29 2020-03-05 Morphic Therapeutic, Inc. Inhibiteurs de l'intégrine (alpha-v)(bêta-6)
WO2020047239A1 (fr) 2018-08-29 2020-03-05 Morphic Therapeutic, Inc. INHIBITION DE L'INTÉGRINE ανβ6
SI3844162T1 (sl) 2018-08-29 2025-06-30 Morphic Therapeutic, Inc. Zaviralci integrina alfa v beta6
WO2021180969A1 (fr) * 2020-03-12 2021-09-16 Technische Universität München Peptides cycliques et leurs conjugués pour l'adressage d'une intégrine alpha-v-bêta-6 in vivo

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4472305A (en) 1983-05-17 1984-09-18 Sterling Drug Inc. Hexapeptide amides
DE4310643A1 (de) 1993-04-01 1994-10-06 Merck Patent Gmbh Cyclische Adhäsionsinhibitoren
DE19538741A1 (de) 1995-10-18 1997-04-24 Merck Patent Gmbh Cyclopeptidderivate
CZ20012212A3 (cs) * 1998-12-19 2001-09-12 Merck Patent Gmbh Peptidická sloučenina, její použití a farmaceutický prostředek, který ji obsahuje

Also Published As

Publication number Publication date
CZ200226A3 (cs) 2002-04-17
JP2003505395A (ja) 2003-02-12
KR20020010928A (ko) 2002-02-06
MXPA02000465A (es) 2002-07-30
DK1196433T3 (da) 2007-02-12
HK1048641A1 (zh) 2003-04-11
CA2379022A1 (fr) 2001-01-25
PL354363A1 (en) 2004-01-12
TWI226890B (en) 2005-01-21
ES2273703T3 (es) 2007-05-16
EP1196433B1 (fr) 2006-09-27
NO20020176L (no) 2002-01-14
AU772782C (en) 2005-01-27
AU5823600A (en) 2001-02-05
AU772782B2 (en) 2004-05-06
PT1196433E (pt) 2007-01-31
DE19933173A1 (de) 2001-01-18
CN1361792A (zh) 2002-07-31
ZA200201275B (en) 2003-08-22
BR0012418A (pt) 2002-03-26
HUP0201925A2 (en) 2002-10-28
HUP0201925A3 (en) 2002-11-28
EP1754714A1 (fr) 2007-02-21
ATE340803T1 (de) 2006-10-15
AR024742A1 (es) 2002-10-23
WO2001005810A2 (fr) 2001-01-25
DE50013525D1 (de) 2006-11-09
WO2001005810A3 (fr) 2001-05-17
SK262002A3 (en) 2002-07-02
EP1196433A2 (fr) 2002-04-17

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