NO20022476D0 - MASP-3, et komplementfikserende enzym og anvendelse derav - Google Patents

MASP-3, et komplementfikserende enzym og anvendelse derav

Info

Publication number
NO20022476D0
NO20022476D0 NO20022476A NO20022476A NO20022476D0 NO 20022476 D0 NO20022476 D0 NO 20022476D0 NO 20022476 A NO20022476 A NO 20022476A NO 20022476 A NO20022476 A NO 20022476A NO 20022476 D0 NO20022476 D0 NO 20022476D0
Authority
NO
Norway
Prior art keywords
masp
complement
fixing enzyme
enzyme
fixing
Prior art date
Application number
NO20022476A
Other languages
English (en)
Other versions
NO20022476L (no
Inventor
Jens Christian Jensenius
Steffen Thiel
Original Assignee
Steffen Thiel
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Steffen Thiel filed Critical Steffen Thiel
Publication of NO20022476L publication Critical patent/NO20022476L/no
Publication of NO20022476D0 publication Critical patent/NO20022476D0/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Urology & Nephrology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Immunology (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
NO20022476A 1999-12-02 2002-05-24 MASP-3, et komplementfikserende enzym og anvendelse derav NO20022476D0 (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DKPA199901721 1999-12-02
DKPA200001126 2000-07-21
PCT/DK2000/000659 WO2001040451A2 (en) 1999-12-02 2000-11-30 Masp-3, a complement-fixing enzyme, and uses for it

Publications (2)

Publication Number Publication Date
NO20022476L NO20022476L (no) 2002-05-24
NO20022476D0 true NO20022476D0 (no) 2002-05-24

Family

ID=26066060

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20022476A NO20022476D0 (no) 1999-12-02 2002-05-24 MASP-3, et komplementfikserende enzym og anvendelse derav

Country Status (9)

Country Link
US (1) US20030186419A1 (no)
EP (1) EP1238066A2 (no)
JP (1) JP2003515338A (no)
CN (1) CN1433466A (no)
AU (1) AU785149B2 (no)
CA (1) CA2391402A1 (no)
NO (1) NO20022476D0 (no)
RU (1) RU2002113381A (no)
WO (1) WO2001040451A2 (no)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7083786B2 (en) 1997-04-03 2006-08-01 Jensenius Jens Chr MASP-2, a complement-fixing enzyme, and uses for it
US7034132B2 (en) 2001-06-04 2006-04-25 Anderson David W Therapeutic polypeptides, nucleic acids encoding same, and methods of use
AU1624501A (en) * 1999-11-23 2001-06-04 Zymogenetics Inc. Human serine protease
WO2001071004A2 (en) * 2000-03-17 2001-09-27 Incyte Genomics, Inc. Proteases
NZ523900A (en) * 2000-07-13 2004-02-27 Jens Christian Jensenius Isolation and characterisation of a mannan-binding lectin (MBL) associated serine protease (MASP-2) and uses thereof to treat infections
WO2002010404A2 (en) * 2000-07-27 2002-02-07 Bayer Aktiengesellschaft Regulation of human masp-like serine protease
US7666627B2 (en) * 2002-08-08 2010-02-23 Targetex Kft. Folded recombinant catalytic fragments of multidomain serine proteases, preparation and uses thereof
DE60310736T2 (de) * 2002-09-10 2007-10-11 Natlmmune A/S Collectin-komplement aktivierende proteinchimären
AU2004216176B2 (en) * 2003-02-21 2008-04-03 Genentech, Inc. Methods for preventing and treating tissue damage associated with ischemia-reperfusion injury
EP1625166B1 (en) 2003-05-12 2015-04-08 Helion Biotech ApS Antibodies to masp-2
US8840893B2 (en) 2004-06-10 2014-09-23 Omeros Corporation Methods for treating conditions associated with MASP-2 dependent complement activation
US7919094B2 (en) * 2004-06-10 2011-04-05 Omeros Corporation Methods for treating conditions associated with MASP-2 dependent complement activation
CN1304568C (zh) * 2004-07-05 2007-03-14 中国人民解放军第二军医大学 新型人补体C1r样丝氨酸蛋白酶类似物,其编码序列及用途
US20120282285A1 (en) * 2009-07-17 2012-11-08 Rigshospitalet Masp isoforms as inhibitors of complement activation
CN102781471B (zh) * 2009-10-16 2016-10-12 奥默罗斯公司 通过抑制masp-2依赖性补体活化治疗弥散性血管内凝血的方法
KR101870915B1 (ko) 2011-04-08 2018-06-25 유니버시티 오브 레스터 Ｍａｓｐ-2 의존적 보체 활성화와 관련된 질병을 치료하는 방법
US9644035B2 (en) 2011-04-08 2017-05-09 Omeros Corporation Methods for treating conditions associated with MASP-2 dependent complement activation
WO2013180834A2 (en) * 2012-04-06 2013-12-05 Omeros Corporation Compositions and methods of inhibting masp-1 and/or masp-3 for the treatment of paroxysmal nocturnal hemoglobinuria
KR102339315B1 (ko) * 2012-06-18 2021-12-15 오메로스 코포레이션 다양한 질환 및 장애의 치료를 위해 masp-1 및/또는 masp-2 및/또는 masp-3를 억제하는 조성물 및 방법
JOP20170154B1 (ar) * 2016-08-01 2023-03-28 Omeros Corp تركيبات وطرق لتثبيط masp-3 لعلاج أمراض واضطرابات مختلفة
WO2021099545A1 (en) * 2019-11-21 2021-05-27 Aarhus Universitet Nanoparticle tracking analysis as a biomarker tool in autoimmune diseases
IL311914A (en) * 2021-10-07 2024-06-01 Omeros Corp Complement-activator-targeted catalytic molecules and methods of using them

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5270199A (en) * 1987-08-20 1993-12-14 The Children's Medical Center Corporation Human mannose-binding protein
AU1624501A (en) * 1999-11-23 2001-06-04 Zymogenetics Inc. Human serine protease
US20020151029A1 (en) * 1999-11-23 2002-10-17 Holloway James L. Human serine protease

Also Published As

Publication number Publication date
WO2001040451A2 (en) 2001-06-07
CN1433466A (zh) 2003-07-30
NO20022476L (no) 2002-05-24
US20030186419A1 (en) 2003-10-02
JP2003515338A (ja) 2003-05-07
WO2001040451A3 (en) 2001-11-29
EP1238066A2 (en) 2002-09-11
AU785149B2 (en) 2006-10-05
AU1693801A (en) 2001-06-12
RU2002113381A (ru) 2004-01-27
CA2391402A1 (en) 2001-06-07

Similar Documents

Publication Publication Date Title
NO20022476L (no) MASP-3, et komplementfikserende enzym og anvendelse derav
DE69505409D1 (de) Verbesserter, proteolytisches enzym enthaltender reiniger
NO20021449D0 (no) Substituerte 2-tio-3,5-dicyano-4-aryl-6-aminopyridiner og anvendelse derav
DK1066374T3 (da) Amylolytiske enzymvarianter
NO20013883D0 (no) Frysetorket middel inneholdende paramylon, samt fremgangsmate og anvendelse derav
EP1158739A4 (en) CLOCK WINNERS AND THESE DEMODULATOR CONTAINING
TR199900531A3 (tr) Pirazolopirimidinler ve pirazolotriazinler.
DK1818396T3 (da) Alpha-amylase varianter
FR2799598B1 (fr) Radiotelephone-bracelet
NO20011216D0 (no) Azetidinderivater, fremstilling og medisiner inneholdende disse
DE60137510D1 (de) Zellwandabbauende enzymvarianten
MA25391A1 (fr) Inhibiteurs d'alcenyl et alcynyl metalloproteases.
DE60013409D1 (de) Alpha-glykosilierte aminosäure freisetzendes enzym
EP1210084A4 (en) PYRIDOMORPHINANS, THIENOMORPHINANS AND THEIR USE
DK1068238T3 (da) Integrinheterodimer og subunit deraf
NO20013853D0 (no) Heteroarylamidiner, metylamidiner og guanidiner som proteaseinhibitorer
EP1263767A4 (en) BETA NETRIN AND ITS USE
NO20003268D0 (no) Hyperhydrert kitikolin, fremgangsmÕte og anvendelse
DE60033943D1 (de) Schwefelfreie enzyme
ID28352A (id) Kompleks enzim oksidase sitokrom c
IT1310418B1 (it) Bracciale biorigenerante.
DE69921018D1 (de) Aufzeichnungsträger, - gerät und -verfahren
DE60005282D1 (de) Golfschlägerkopf, golfschläger und golfschlägerset
NO20021498D0 (no) PRV-1-genet og anvendelsen av dette
EP1172439A4 (en) THERMOSTABLE ENZYME WITH AMINOTRANSFERASE ACTIVITY AND FOR THIS ENCODING GENE

Legal Events

Date Code Title Description
FC2A Withdrawal, rejection or dismissal of laid open patent application