NO20022476L - MASP-3, et komplementfikserende enzym og anvendelse derav - Google Patents

MASP-3, et komplementfikserende enzym og anvendelse derav

Info

Publication number
NO20022476L
NO20022476L NO20022476A NO20022476A NO20022476L NO 20022476 L NO20022476 L NO 20022476L NO 20022476 A NO20022476 A NO 20022476A NO 20022476 A NO20022476 A NO 20022476A NO 20022476 L NO20022476 L NO 20022476L
Authority
NO
Norway
Prior art keywords
masp
complement
fixing enzyme
enzyme
fixing
Prior art date
Application number
NO20022476A
Other languages
English (en)
Other versions
NO20022476D0 (no
Inventor
Jens Christian Jensenius
Steffen Thiel
Original Assignee
Steffen Thiel
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Steffen Thiel filed Critical Steffen Thiel
Publication of NO20022476L publication Critical patent/NO20022476L/no
Publication of NO20022476D0 publication Critical patent/NO20022476D0/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Vascular Medicine (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Urology & Nephrology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
NO20022476A 1999-12-02 2002-05-24 MASP-3, et komplementfikserende enzym og anvendelse derav NO20022476D0 (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DKPA199901721 1999-12-02
DKPA200001126 2000-07-21
PCT/DK2000/000659 WO2001040451A2 (en) 1999-12-02 2000-11-30 Masp-3, a complement-fixing enzyme, and uses for it

Publications (2)

Publication Number Publication Date
NO20022476L true NO20022476L (no) 2002-05-24
NO20022476D0 NO20022476D0 (no) 2002-05-24

Family

ID=26066060

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20022476A NO20022476D0 (no) 1999-12-02 2002-05-24 MASP-3, et komplementfikserende enzym og anvendelse derav

Country Status (9)

Country Link
US (1) US20030186419A1 (no)
EP (1) EP1238066A2 (no)
JP (1) JP2003515338A (no)
CN (1) CN1433466A (no)
AU (1) AU785149B2 (no)
CA (1) CA2391402A1 (no)
NO (1) NO20022476D0 (no)
RU (1) RU2002113381A (no)
WO (1) WO2001040451A2 (no)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6969601B2 (en) 1997-04-03 2005-11-29 Jensenius Jens Chr MASP-2, a complement-fixing enzyme, and uses for it
US7034132B2 (en) 2001-06-04 2006-04-25 Anderson David W Therapeutic polypeptides, nucleic acids encoding same, and methods of use
WO2001038501A2 (en) * 1999-11-23 2001-05-31 Zymogenetics, Inc. Human serine protease
JP2004501612A (ja) * 2000-03-17 2004-01-22 インサイト・ゲノミックス・インコーポレイテッド プロテアーゼ
JP5226169B2 (ja) 2000-07-13 2013-07-03 ヘリオン バイオテック アンパーツゼルスカブ Ｍａｓｐ−２、すなわち補体固定酵素及びその使用
WO2002010404A2 (en) * 2000-07-27 2002-02-07 Bayer Aktiengesellschaft Regulation of human masp-like serine protease
US7666627B2 (en) * 2002-08-08 2010-02-23 Targetex Kft. Folded recombinant catalytic fragments of multidomain serine proteases, preparation and uses thereof
ES2279981T3 (es) * 2002-09-10 2007-09-01 Natlmmune A/S Proteinas quimericas activantes de colectina-complemento.
AU2004216176B2 (en) 2003-02-21 2008-04-03 Genentech, Inc. Methods for preventing and treating tissue damage associated with ischemia-reperfusion injury
HUE034760T2 (en) 2003-05-12 2018-02-28 Helion Biotech Aps Masp-2-T binding antibodies
US7919094B2 (en) * 2004-06-10 2011-04-05 Omeros Corporation Methods for treating conditions associated with MASP-2 dependent complement activation
US8840893B2 (en) 2004-06-10 2014-09-23 Omeros Corporation Methods for treating conditions associated with MASP-2 dependent complement activation
CN1304568C (zh) * 2004-07-05 2007-03-14 中国人民解放军第二军医大学 新型人补体C1r样丝氨酸蛋白酶类似物,其编码序列及用途
CA2767755C (en) 2009-07-17 2021-10-12 Rigshospitalet Inhibitors of complement activation
EP3150635A3 (en) * 2009-10-16 2017-06-21 Omeros Corporation Methods for treating disseminated intravascular coagulation by inhibiting masp-2 dependent complement activation
DK2694108T3 (en) 2011-04-08 2018-08-20 Univ Leicester METHODS OF TREATING DISEASES ASSOCIATED WITH MASP-2 DEPENDENT COMPLEMENT ACTIVATION
US9644035B2 (en) 2011-04-08 2017-05-09 Omeros Corporation Methods for treating conditions associated with MASP-2 dependent complement activation
NZ629675A (en) * 2012-04-06 2017-02-24 Omeros Corp Compositions and methods of inhibiting masp-1, masp-2 and/or masp-3 for treatment of paroxysmal nocturnal hemoglobinuria
PT2861246T (pt) * 2012-06-18 2021-04-05 Univ Leicester Composições e métodos para inibir masp-1 e/ou masp-2 e/ou masp-3 para o tratamento de várias doenças e perturbações
JOP20170154B1 (ar) * 2016-08-01 2023-03-28 Omeros Corp تركيبات وطرق لتثبيط masp-3 لعلاج أمراض واضطرابات مختلفة
WO2021099545A1 (en) * 2019-11-21 2021-05-27 Aarhus Universitet Nanoparticle tracking analysis as a biomarker tool in autoimmune diseases
AU2022361048B2 (en) * 2021-10-07 2026-04-02 Omeros Corporation Targeted catalytic complement-activating molecules and methods of use thereof

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5270199A (en) * 1987-08-20 1993-12-14 The Children's Medical Center Corporation Human mannose-binding protein
US20020151029A1 (en) * 1999-11-23 2002-10-17 Holloway James L. Human serine protease
WO2001038501A2 (en) * 1999-11-23 2001-05-31 Zymogenetics, Inc. Human serine protease

Also Published As

Publication number Publication date
CN1433466A (zh) 2003-07-30
CA2391402A1 (en) 2001-06-07
AU785149B2 (en) 2006-10-05
EP1238066A2 (en) 2002-09-11
WO2001040451A3 (en) 2001-11-29
NO20022476D0 (no) 2002-05-24
JP2003515338A (ja) 2003-05-07
RU2002113381A (ru) 2004-01-27
US20030186419A1 (en) 2003-10-02
AU1693801A (en) 2001-06-12
WO2001040451A2 (en) 2001-06-07

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