NO20022869L - Kvart¶rn¶re salter av N-substituerte cykliske eller acykliske aminer som farmasöytiske midler - Google Patents

Kvart¶rn¶re salter av N-substituerte cykliske eller acykliske aminer som farmasöytiske midler

Info

Publication number
NO20022869L
NO20022869L NO20022869A NO20022869A NO20022869L NO 20022869 L NO20022869 L NO 20022869L NO 20022869 A NO20022869 A NO 20022869A NO 20022869 A NO20022869 A NO 20022869A NO 20022869 L NO20022869 L NO 20022869L
Authority
NO
Norway
Prior art keywords
pharmaceutical agents
substituted cyclic
quaternary salts
acyclic amines
acyclic
Prior art date
Application number
NO20022869A
Other languages
English (en)
Norwegian (no)
Other versions
NO20022869D0 (no
Inventor
Lewis Siu Leung Choi
Gregory N Beatch
Clive P Page
Original Assignee
Ucb Farchim Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ucb Farchim Sa filed Critical Ucb Farchim Sa
Publication of NO20022869D0 publication Critical patent/NO20022869D0/no
Publication of NO20022869L publication Critical patent/NO20022869L/no

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/14—Antitussive agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/52—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton
    • C07C229/54—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton with amino and carboxyl groups bound to carbon atoms of the same non-condensed six-membered aromatic ring
    • C07C229/60—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton with amino and carboxyl groups bound to carbon atoms of the same non-condensed six-membered aromatic ring with amino and carboxyl groups bound in meta- or para- positions
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/52—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton
    • C07C229/54—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton with amino and carboxyl groups bound to carbon atoms of the same non-condensed six-membered aromatic ring
    • C07C229/64—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton with amino and carboxyl groups bound to carbon atoms of the same non-condensed six-membered aromatic ring the carbon skeleton being further substituted by singly-bound oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/28—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton
    • C07C237/34—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton having the nitrogen atom of the carboxamide group bound to an acyclic carbon atom of a hydrocarbon radical substituted by nitrogen atoms not being part of nitro or nitroso groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
    • C07D295/125—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/13—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pulmonology (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Hydrogenated Pyridines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
NO20022869A 1999-12-15 2002-06-14 Kvart¶rn¶re salter av N-substituerte cykliske eller acykliske aminer som farmasöytiske midler NO20022869L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CA2292350 1999-12-15
PCT/CA2000/001507 WO2001044218A1 (en) 1999-12-15 2000-12-15 Quaternary salts of n-substituted cyclic or acyclic amines as pharmaceuticals

Publications (2)

Publication Number Publication Date
NO20022869D0 NO20022869D0 (no) 2002-06-14
NO20022869L true NO20022869L (no) 2002-08-14

Family

ID=4164886

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20022869A NO20022869L (no) 1999-12-15 2002-06-14 Kvart¶rn¶re salter av N-substituerte cykliske eller acykliske aminer som farmasöytiske midler

Country Status (21)

Country Link
US (1) US20040214867A1 (is)
EP (1) EP1278736A1 (is)
JP (1) JP2003516982A (is)
KR (1) KR20020075871A (is)
CN (1) CN1423641A (is)
AU (1) AU2334601A (is)
BG (1) BG106814A (is)
BR (1) BR0016430A (is)
CZ (1) CZ20022096A3 (is)
EE (1) EE200200316A (is)
HU (1) HUP0204014A3 (is)
IL (1) IL150180A0 (is)
IS (1) IS6415A (is)
MX (1) MXPA02006050A (is)
NO (1) NO20022869L (is)
NZ (1) NZ519746A (is)
PL (1) PL355904A1 (is)
RU (1) RU2002116211A (is)
WO (1) WO2001044218A1 (is)
YU (1) YU44202A (is)
ZA (1) ZA200205568B (is)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8148057B2 (en) * 2005-06-21 2012-04-03 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services, Centers For Disease Control And Prevention Methods, immunoassays and devices for detection of anti-lipoidal antibodies
BRPI0611866B8 (pt) * 2005-06-21 2021-07-27 The Government Of The Us Secretary Of The Department Of Health And Human Services Centers For Diseas dispositivo de fluxo lateral de imunoensaio, dispositivo de fluxo direto de imunoensaio, método para detectar anticorpos antilipoidais em um sujeito, método para para diagnosticar sífilis em um sujeito e métodos para imobilizar cardiolipina imunorreativa sobre um substrato microporoso
EP2101819B1 (en) 2006-11-20 2013-01-09 President and Fellows of Harvard College Methods, compositions, and kits for treating pain and pruritis
EP2995303A1 (en) 2009-07-10 2016-03-16 President and Fellows of Harvard College Permanently charged sodium and calcium channel blockers as anti-inflammatory agents
ES2596215T3 (es) 2011-10-24 2017-01-05 Asana Biosciences, Llc Ciclohexilaminas
WO2017024037A1 (en) * 2015-08-03 2017-02-09 President And Fellows Of Harvard College Charged ion channel blockers and methods for use
EP3937945A4 (en) 2019-03-11 2023-01-04 Nocion Therapeutics, Inc. Charged ion channel blockers and methods for use
US10786485B1 (en) 2019-03-11 2020-09-29 Nocion Therapeutics, Inc. Charged ion channel blockers and methods for use
MA55307A (fr) 2019-03-11 2022-01-19 Nocion Therapeutics Inc Bloqueurs de canaux ioniques chargés et procédés d'utilisation
US10780083B1 (en) 2019-03-11 2020-09-22 Nocion Therapeutics, Inc. Charged ion channel blockers and methods for use
BR112021017809A2 (pt) 2019-03-11 2021-11-23 Nocion Therapeutics Inc Bloqueadores de canais iônicos substituídos por éster e métodos para uso
WO2021091585A1 (en) 2019-11-06 2021-05-14 Nocion Therapeutics, Inc. Charged ion channel blockers and methods for use
US10933055B1 (en) 2019-11-06 2021-03-02 Nocion Therapeutics, Inc. Charged ion channel blockers and methods for use
US12162851B2 (en) 2020-03-11 2024-12-10 Nocion Therapeutics, Inc. Charged ion channel blockers and methods for use
JP7708777B2 (ja) 2020-03-11 2025-07-15 ノシオン セラピューティクス，インコーポレイテッド 荷電したイオンチャンネル遮断薬および使用方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4060637A (en) * 1971-06-21 1977-11-29 Pierre Fabre Sa Medicaments having psychotropic properties
US4048335A (en) * 1974-06-17 1977-09-13 The Regents Of The University Of Michigan Method of inhibiting myocardial ischemia in mammals using quaternary salts
US5110977A (en) * 1990-02-14 1992-05-05 Eastman Kodak Company Ester-containing quaternary ammonium salts as adhesion improving toner charge agents
CA2095495C (en) * 1992-06-01 2002-06-04 Stephen Carl Hasselberg Assay for serum cholinesterase
US5451394A (en) * 1993-08-25 1995-09-19 Isp Van Dyk Inc. Quaternary salts of para-dialkylamino benzamide derivatives
FR2717174B1 (fr) * 1994-03-14 1996-05-31 Sanofi Sa Utilisation de pipéridinoéthyl esters de l'acide 4-amino-5-chloro-2-méthoxybenzoïque comme 5-HT4 agonistes.

Also Published As

Publication number Publication date
IL150180A0 (en) 2002-12-01
NZ519746A (en) 2004-05-28
BG106814A (en) 2003-04-30
CN1423641A (zh) 2003-06-11
CZ20022096A3 (cs) 2003-02-12
JP2003516982A (ja) 2003-05-20
ZA200205568B (en) 2003-10-13
NO20022869D0 (no) 2002-06-14
MXPA02006050A (es) 2004-08-23
BR0016430A (pt) 2002-08-20
HUP0204014A3 (en) 2005-04-28
YU44202A (sh) 2005-11-28
RU2002116211A (ru) 2004-02-10
KR20020075871A (ko) 2002-10-07
PL355904A1 (en) 2004-05-31
WO2001044218A1 (en) 2001-06-21
HUP0204014A2 (hu) 2003-03-28
US20040214867A1 (en) 2004-10-28
EP1278736A1 (en) 2003-01-29
IS6415A (is) 2002-06-12
AU2334601A (en) 2001-06-25
EE200200316A (et) 2003-08-15

Similar Documents

Publication Publication Date Title
NO20022869D0 (no) Kvart¶rn¶re salter av N-substituerte cykliske eller acykliske aminer som farmasöytiske midler
NO20021450D0 (no) Cykliske aminforbindelser som CCR5 antagonister
NO20002486L (no) Sykliske aminderivater og deres anvendelse som legemidler
NO20041609L (no) Kvaternaere ammoniumsalter av omega-aminoalkylamider av R-2-aryl-propionsyrer og farmasoytiske sammensetninger som inneholder disse
FR15C0096I2 (fr) Derives carbamoyloxyalkyl-azolium n-substitues
NO20014409L (no) Dimere forbindelser og deres anvendelse som inhibitorer av neuraminidase
NO20035739D0 (no) N-aroyl syklisk aminderivater som orexin reseptorantagonister
NO20016283D0 (no) Tidsbestemte doseringsformer med dobbeltfrigivelse som omfatter et kortvirkende hypnotikum eller et salt derav
NO20020383D0 (no) Mutilinderivater og deres anvendelse som anti-bakterielle midler
NO20014483L (no) Aminderivater som proteaseinhibitorer
NO20015365D0 (no) Piperidinderivater som er anvendbare som CCR5-antagonister
NO980817D0 (no) Meta-guanidin-, urea-, tiourea- eller azacykliske aminobenzosyrederivater som integrin-antagonister
NO20035729L (no) Piperidinderivater som er nyttige som modulatorer av kemokin-reseptor-aktivitet
NO20021329L (no) Kinaseinhibitorer som terapeutiske midler
NO20003118L (no) Acylguanidinderivater som inhibitorer av benresorpsjon og som vitronektinreseptorantagonister
NO20043702L (no) 8-azaprostaglandinderivatforbindelser og legemidler inneholdende forbindelsene som den aktive bestanddel
NO20013600D0 (no) Acylderivater som behandler VLA-4 relaterte forstyrrelser
DK1498411T3 (da) Diketohydrazinderivatforbindelser og medikamenter indeholdende forbindelserne som den aktive bestanddel
NO20021253D0 (no) Quinolyl propyl piperidinderivater og deres bruk som antibakterielle midler
NO20015064L (no) Karbaminsyre-derivater og deres anvendelse som metabotrope glutamat-reseptor-ligander
NO20004261L (no) 2-aryletyl-(piperidin-4-ylmetyl)aminderivater som muscarin- reseptor antagonister
NO20025640L (no) Substituerte 1-aminoalkyl-laktamer og deres anvendelse som muscarin-reseptorantagonister
NO20015897D0 (no) Indolylpiperidinderivater som antihistaminiske og antiallergiske midler
EE200100383A (et) L-fenüülefriinvesinikkloriidi valmistamise meetod
EE200200314A (et) Tsüklilised kvaternaarsed ammooniumiühendid

Legal Events

Date Code Title Description
FC2A Withdrawal, rejection or dismissal of laid open patent application