|
JP4274583B2
(ja)
|
1996-11-18 |
2009-06-10 |
ゲゼルシャフト・フュア・ビオテクノロギッシェ・フォルシュンク・ミット・ベシュレンクテル・ハフツング(ゲー・ベー・エフ) |
エポチロンc,d,e及びf、製造と薬剤
|
|
US20050043376A1
(en)
*
|
1996-12-03 |
2005-02-24 |
Danishefsky Samuel J. |
Synthesis of epothilones, intermediates thereto, analogues and uses thereof
|
|
US6204388B1
(en)
|
1996-12-03 |
2001-03-20 |
Sloan-Kettering Institute For Cancer Research |
Synthesis of epothilones, intermediates thereto and analogues thereof
|
|
US6242469B1
(en)
|
1996-12-03 |
2001-06-05 |
Sloan-Kettering Institute For Cancer Research |
Synthesis of epothilones, intermediates thereto, analogues and uses thereof
|
|
US6867305B2
(en)
*
|
1996-12-03 |
2005-03-15 |
Sloan-Kettering Institute For Cancer Research |
Synthesis of epothilones, intermediates thereto and analogues thereof
|
|
US20020058286A1
(en)
*
|
1999-02-24 |
2002-05-16 |
Danishefsky Samuel J. |
Synthesis of epothilones, intermediates thereto and analogues thereof
|
|
US20020077301A1
(en)
*
|
2000-10-05 |
2002-06-20 |
Whitehead Institute For Biomedical Research |
Effects of combined administration of farnesyl transferase inhibitors and signal transduction inhibitors
|
|
CZ20031262A3
(en)
*
|
2000-10-16 |
2004-03-17 |
Neopharm, Inc. |
Liposomal formulation of mitoxantrone
|
|
US20050209310A1
(en)
*
|
2000-12-22 |
2005-09-22 |
Chaplin David J |
Methods for modulating tumor growth and metastasis
|
|
US7037906B1
(en)
*
|
2000-12-22 |
2006-05-02 |
Oxigene, Inc. |
Methods for modulating tumor growth and metastasis
|
|
CA2440555A1
(en)
*
|
2001-03-14 |
2002-09-19 |
Bristol-Myers Squibb Company |
Combination of epothilone analogs and chemotherapeutic agents for the treatment of proliferative diseases
|
|
BR0209647A
(pt)
*
|
2001-05-16 |
2004-07-27 |
Novartis Ag |
Combinação que compreende n-{5-[4-(4-metil-piperazino-metil)-benzoilamido]-2-metil fenil}-4-(3-piridil)-2-pirimidina-amina e um agente quimioterapêutico
|
|
DE60224299T2
(de)
*
|
2001-10-25 |
2008-12-11 |
Novartis Ag |
Kombinationsmedikationen mit einem selektiven cyclooxygenase-2-inhibitor
|
|
GB0126879D0
(en)
*
|
2001-11-08 |
2002-01-02 |
Astrazeneca Ab |
Combination therapy
|
|
US7074921B2
(en)
*
|
2001-11-13 |
2006-07-11 |
Bristol Myers Squibb Company |
Process for the preparation of 3,7-disubstituted-2,3,4,5-tetrahydro-1H-1,4-benzodiazepine compounds
|
|
TW200408407A
(en)
*
|
2001-11-30 |
2004-06-01 |
Dana Farber Cancer Inst Inc |
Methods and compositions for modulating the immune system and uses thereof
|
|
EP1465618A2
(en)
*
|
2001-12-20 |
2004-10-13 |
Bristol-Myers Squibb Company |
Pharmaceutical compositions of orally active taxane derivatives having enhanced bioavailability
|
|
US6998391B2
(en)
*
|
2002-02-07 |
2006-02-14 |
Supergen.Inc. |
Method for treating diseases associated with abnormal kinase activity
|
|
US20030147813A1
(en)
*
|
2002-02-07 |
2003-08-07 |
John Lyons |
Method for treating chronic myelogenous leukemia
|
|
RS96304A
(sr)
*
|
2002-05-17 |
2006-10-27 |
Aventis Pharma S.A. |
Primena docetaksel/doksorubicin/ ciklofosfamida u adjuvantnoj terapiji raka dojke i jajnika
|
|
NZ536475A
(en)
*
|
2002-05-24 |
2008-06-30 |
Schering Corp |
Neutralizing human anti-igfr antibody
|
|
US6627614B1
(en)
*
|
2002-06-05 |
2003-09-30 |
Super Gen, Inc. |
Sequential therapy comprising a 20(S)-camptothecin and an anthracycline
|
|
RU2379032C9
(ru)
*
|
2002-06-10 |
2010-03-27 |
Новартис Аг |
Комбинации, включающие эпотилоны, и их фармацевтическое применение
|
|
BR0311714A
(pt)
*
|
2002-06-10 |
2005-03-01 |
Novartis Ag |
Combinações que compreendem epotilonas e seus usos farmacêuticos
|
|
US6921769B2
(en)
|
2002-08-23 |
2005-07-26 |
Sloan-Kettering Institute For Cancer Research |
Synthesis of epothilones, intermediates thereto and analogues thereof
|
|
US7649006B2
(en)
|
2002-08-23 |
2010-01-19 |
Sloan-Kettering Institute For Cancer Research |
Synthesis of epothilones, intermediates thereto and analogues thereof
|
|
WO2004018478A2
(en)
*
|
2002-08-23 |
2004-03-04 |
Sloan-Kettering Institute For Cancer Research |
Synthesis of epothilones, intermediates thereto, analogues and uses thereof
|
|
US20040209930A1
(en)
*
|
2002-10-02 |
2004-10-21 |
Carboni Joan M. |
Synergistic methods and compositions for treating cancer
|
|
GB0223380D0
(en)
*
|
2002-10-09 |
2002-11-13 |
Astrazeneca Ab |
Combination therapy
|
|
US8613922B2
(en)
|
2003-04-24 |
2013-12-24 |
The University Of North Carolina At Chapel Hill |
Methods for inhibiting diabetic retinopathy with an antibody against integrin associated protein (IAP)
|
|
US20050043233A1
(en)
*
|
2003-04-29 |
2005-02-24 |
Boehringer Ingelheim International Gmbh |
Combinations for the treatment of diseases involving cell proliferation, migration or apoptosis of myeloma cells or angiogenesis
|
|
WO2005000230A2
(en)
*
|
2003-06-05 |
2005-01-06 |
Charles Achkar |
Methods of treating hyperproliferative cell disorders
|
|
EP1493445A1
(en)
*
|
2003-07-04 |
2005-01-05 |
Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. |
Inhibition of stress-induced ligand-dependent EGFR activation
|
|
NZ592039A
(en)
*
|
2003-08-27 |
2013-03-28 |
Ophthotech Corp |
Combination therapy for the treatment of ocular neovascular disorders
|
|
ATE514783T1
(de)
|
2003-11-12 |
2011-07-15 |
Schering Corp |
Plasmidsystem zur expression mehrerer gene
|
|
WO2005046665A1
(en)
*
|
2003-11-13 |
2005-05-26 |
Warner-Lambert Company Llc |
Combination chemotherapy comprising a mek inhibitor and a erbb1/2 receptor inhibitor
|
|
PE20050928A1
(es)
*
|
2003-11-21 |
2005-11-08 |
Schering Corp |
Combinaciones terapeuticas de anticuerpo anti-igfr1
|
|
US7612071B2
(en)
*
|
2004-03-12 |
2009-11-03 |
Syntrix Biosystems, Inc. |
Compositions and methods employing aminopterin
|
|
US20070293539A1
(en)
*
|
2004-03-18 |
2007-12-20 |
Lansbury Peter T |
Methods for the treatment of synucleinopathies
|
|
WO2005089518A2
(en)
*
|
2004-03-18 |
2005-09-29 |
The Brigham And Women's Hospital, Inc. |
Uch-l1 expression and cancer therapy
|
|
JP2007529555A
(ja)
*
|
2004-03-18 |
2007-10-25 |
ザ ブライハム アンド ウイメンズ ホスピタル, インコーポレイテッド |
シヌクレイノパチーを治療する方法
|
|
WO2005089515A2
(en)
*
|
2004-03-18 |
2005-09-29 |
The Brigham And Women's Hospital, Inc. |
Methods for the treatment of synucleinopathies
|
|
EP1744751A4
(en)
*
|
2004-03-18 |
2010-03-10 |
Brigham & Womens Hospital |
METHOD FOR THE TREATMENT OF SYNUCLEINOPATHIES
|
|
US20060106060A1
(en)
*
|
2004-03-18 |
2006-05-18 |
The Brigham And Women's Hospital, Inc. |
Methods for the treatment of synucleinopathies (Lansbury)
|
|
US20080113039A1
(en)
*
|
2004-03-23 |
2008-05-15 |
Stephen Robert Wedge |
Combination Therapy
|
|
GB0406446D0
(en)
*
|
2004-03-23 |
2004-04-28 |
Astrazeneca Ab |
Combination therapy
|
|
EP1735350B1
(en)
|
2004-04-15 |
2010-08-25 |
Genencor International, Inc. |
Anti-cea scfv - beta-lactamase constructs (cab molecules) in adept
|
|
US7449196B2
(en)
*
|
2004-07-09 |
2008-11-11 |
Robert Sabin |
Anti tumor compositions and methods of use
|
|
RU2342159C2
(ru)
*
|
2004-07-16 |
2008-12-27 |
Пфайзер Продактс Инк. |
Комбинированная терапия негематологических злокачественных опухолей с использованием анти-igf-1r-антитела
|
|
GB0419071D0
(en)
|
2004-08-26 |
2004-09-29 |
Mgx Internat Ltd |
Display device
|
|
GB0424339D0
(en)
*
|
2004-11-03 |
2004-12-08 |
Astrazeneca Ab |
Combination therapy
|
|
TW200628156A
(en)
*
|
2004-11-04 |
2006-08-16 |
Bristol Myers Squibb Co |
Combination of a SRC kinase inhibitor and a BCR-ABL inhibitor for the treatment of proliferative diseases
|
|
DE602005025685D1
(de)
*
|
2004-12-03 |
2011-02-10 |
Schering Corp |
Biologische marker zur vorauswahl von patienten für die anti-igf1r-therapie
|
|
EP1839662B1
(en)
*
|
2005-01-19 |
2010-03-24 |
Zeria Pharmaceutical Co., Ltd. |
Antitumor agent
|
|
CN108421044A
(zh)
|
2005-02-03 |
2018-08-21 |
综合医院公司 |
治疗吉非替尼耐药性癌症的方法
|
|
JP2008536479A
(ja)
|
2005-02-11 |
2008-09-11 |
ユニバーシティ オブ サザン カリフォルニア |
ジスルフィド架橋を有するタンパク質の発現法
|
|
US20060194821A1
(en)
*
|
2005-02-18 |
2006-08-31 |
The Brigham And Women's Hospital, Inc. |
Compounds inhibiting the aggregation of superoxide dismutase-1
|
|
RU2276613C1
(ru)
*
|
2005-03-17 |
2006-05-20 |
Российская медицинская академия последипломного образования Министерства здравоохранения Российской Федерации (РМАПО МЗ РФ) |
Способ лечения злокачественных опухолей головки поджелудочной железы
|
|
US20060235006A1
(en)
*
|
2005-04-13 |
2006-10-19 |
Lee Francis Y |
Combinations, methods and compositions for treating cancer
|
|
US20060233810A1
(en)
*
|
2005-04-15 |
2006-10-19 |
Yaolin Wang |
Methods and compositions for treating or preventing cancer
|
|
WO2006116076A2
(en)
|
2005-04-28 |
2006-11-02 |
Genencor International, Inc. |
Tab molecules
|
|
AR053272A1
(es)
|
2005-05-11 |
2007-04-25 |
Hoffmann La Roche |
Determinacion de responsivos a la quimioterapia
|
|
AU2006259536A1
(en)
*
|
2005-06-15 |
2006-12-28 |
Schering Corporation |
Anti-IGF1R antibody formulations
|
|
FR2887454B1
(fr)
*
|
2005-06-28 |
2009-06-05 |
Sanofi Aventis Sa |
Combinaisons antitumorales contenant des derives du taxane et des sigma ligands
|
|
BRPI0618042A2
(pt)
|
2005-11-04 |
2011-08-16 |
Wyeth Corp |
usos de uma rapamicina e de uma herceptina, produto, pacote farmacêutico, e, composição farmacêutica
|
|
US8546404B2
(en)
|
2005-12-13 |
2013-10-01 |
Merck Sharp & Dohme |
Compounds that are ERK inhibitors
|
|
EP1984331B1
(en)
|
2006-02-16 |
2010-10-20 |
Schering Corporation |
Pyrrolidine derivatives as erk inhibitors
|
|
US8044033B2
(en)
*
|
2006-03-02 |
2011-10-25 |
The Board Of Regents Of The University Of Texas System |
Fluorocytidine derivatives and COX-2 inhibitors for the treatment of cancer
|
|
US8008256B2
(en)
*
|
2006-05-01 |
2011-08-30 |
University Of Southern California |
Combination therapy for treatment of cancer
|
|
RU2325914C2
(ru)
*
|
2006-06-15 |
2008-06-10 |
Государственное учреждение научно-исследовательский институт онкологии Томского Научного центра Сибирского отделения Российской академии медицинских наук (ГУ НИИ онкологии ТНЦ СО РАМН) |
Способ лечения операбельного рака молочной железы
|
|
US20080081051A1
(en)
*
|
2006-09-28 |
2008-04-03 |
Robert Sabin |
Method of manufacturing anti-tumor and anti-viral compositions
|
|
US20080085881A1
(en)
*
|
2006-10-06 |
2008-04-10 |
Aimery De Gramont |
Stop-and-go oxaliplatin treatment regimens
|
|
WO2008065409A2
(en)
*
|
2006-12-01 |
2008-06-05 |
Betagenon Ab |
Combination for use in the treatment of cancer, comprising tamoxifen or an aromatase inhibitor
|
|
AU2008222592B2
(en)
*
|
2007-03-02 |
2013-09-26 |
Detsamma Investments Pty Ltd |
Compositions and methods for delivery of anti-cancer agents
|
|
US20100111874A1
(en)
*
|
2007-03-19 |
2010-05-06 |
University Of Medicine And Dentistry Of New Jresey |
Method of cancer detection and treatment
|
|
JP5474792B2
(ja)
*
|
2007-09-10 |
2014-04-16 |
キュリス,インコーポレイテッド |
亜鉛結合部分を含むキナゾリンベースegfrインヒビターの酒石酸塩またはその複合体
|
|
WO2009033204A1
(en)
*
|
2007-09-12 |
2009-03-19 |
University Of Wollongong |
Multi-component compositions and methods for delivery of anti-cancer agents
|
|
US8022216B2
(en)
|
2007-10-17 |
2011-09-20 |
Wyeth Llc |
Maleate salts of (E)-N-{4-[3-chloro-4-(2-pyridinylmethoxy)anilino]-3-cyano-7-ethoxy-6-quinolinyl}-4-(dimethylamino)-2-butenamide and crystalline forms thereof
|
|
EP2082745B1
(en)
|
2007-12-28 |
2012-12-19 |
Deutsches Krebsforschungszentrum, Stiftung des öffentlichen Rechts |
Cancer therapy with a parvovirus combined with chemotherapy
|
|
EP2236145B1
(en)
*
|
2008-01-28 |
2014-05-14 |
NanoCarrier Co., Ltd. |
Pharmaceutical composition and combined agent
|
|
RU2525389C2
(ru)
|
2008-02-21 |
2014-08-10 |
Мерк Шарп И Доум Корп. |
Соединения, которые являются ингибиторами erk
|
|
US8232402B2
(en)
*
|
2008-03-12 |
2012-07-31 |
Link Medicine Corporation |
Quinolinone farnesyl transferase inhibitors for the treatment of synucleinopathies and other indications
|
|
US20110182888A1
(en)
*
|
2008-04-08 |
2011-07-28 |
Peter Ordentlich |
Administration of an Inhibitor of HDAC, an Inhibitor of HER-2, and a Selective Estrogen Receptor Modulator
|
|
RU2365370C1
(ru)
*
|
2008-04-29 |
2009-08-27 |
Государственное учреждение Российский онкологический научный центр им. Н.Н. Блохина РАМН |
Способ лечения рака легкого
|
|
CN102641270A
(zh)
|
2008-06-17 |
2012-08-22 |
惠氏有限责任公司 |
含有hki-272和长春瑞滨的抗肿瘤组合
|
|
US20110060005A1
(en)
*
|
2008-11-13 |
2011-03-10 |
Link Medicine Corporation |
Treatment of mitochondrial disorders using a farnesyl transferase inhibitor
|
|
MX2011005096A
(es)
*
|
2008-11-13 |
2011-11-18 |
Link Medicine Corp |
Derivados de azaquinolinona y usos de los mismos.
|
|
US20100331363A1
(en)
*
|
2008-11-13 |
2010-12-30 |
Link Medicine Corporation |
Treatment of mitochondrial disorders using a farnesyl transferase inhibitor
|
|
US8802394B2
(en)
|
2008-11-13 |
2014-08-12 |
Radu O. Minea |
Method of expressing proteins with disulfide bridges with enhanced yields and activity
|
|
ES2573295T3
(es)
*
|
2008-11-28 |
2016-06-07 |
Novartis Ag |
Combinaciones farmacéuticas que comprenden un inhibidor de Hsp90 derivado de isoxazol y el inhibidor de HER2 trastuzumab
|
|
WO2010099139A2
(en)
|
2009-02-25 |
2010-09-02 |
Osi Pharmaceuticals, Inc. |
Combination anti-cancer therapy
|
|
US8642834B2
(en)
|
2009-02-27 |
2014-02-04 |
OSI Pharmaceuticals, LLC |
Methods for the identification of agents that inhibit mesenchymal-like tumor cells or their formation
|
|
US8465912B2
(en)
|
2009-02-27 |
2013-06-18 |
OSI Pharmaceuticals, LLC |
Methods for the identification of agents that inhibit mesenchymal-like tumor cells or their formation
|
|
WO2010099138A2
(en)
|
2009-02-27 |
2010-09-02 |
Osi Pharmaceuticals, Inc. |
Methods for the identification of agents that inhibit mesenchymal-like tumor cells or their formation
|
|
CN103037903A
(zh)
|
2010-05-18 |
2013-04-10 |
天蓝制药公司 |
用于治疗自身免疫性疾病或其它疾病的组合物和方法
|
|
SI2500036T1
(sl)
*
|
2011-03-18 |
2014-09-30 |
Metheresis Translational Research Sa |
Met inhibitorji za izboljĺ anje uäśinkovitosti obsevanja
|
|
JP2014519813A
(ja)
|
2011-04-25 |
2014-08-21 |
オーエスアイ・ファーマシューティカルズ,エルエルシー |
癌薬剤発見、診断、および治療におけるemt遺伝子シグネチャーの使用
|
|
WO2013152252A1
(en)
|
2012-04-06 |
2013-10-10 |
OSI Pharmaceuticals, LLC |
Combination anti-cancer therapy
|
|
CN103374000B
(zh)
*
|
2012-04-13 |
2015-11-11 |
中国科学院广州生物医药与健康研究院 |
嘧啶并二氮杂卓类化合物及其药用组合物和应用
|
|
KR102948178B1
(ko)
|
2013-07-12 |
2026-04-10 |
아스텔라스 유에스 엘엘씨 |
안과적 질환을 치료하거나 예방하기 위한 방법
|
|
CN107043456B
(zh)
*
|
2017-04-19 |
2019-05-17 |
川北医学院 |
对氧环己酮与l-苯丙氨酸氮芥共聚物及其应用
|
|
CA3068256A1
(en)
|
2017-06-21 |
2018-12-27 |
The University Of North Carolina At Chapel Hill |
Methods and compositions for chimeric antigen receptor targeting cancer cells
|
|
US12428490B2
(en)
|
2018-06-13 |
2025-09-30 |
The University Of North Carolina At Chapel Hill |
Methods and compositions for chimeric antigen receptor targeting cancer cells
|
|
US11068254B1
(en)
|
2020-06-10 |
2021-07-20 |
Cigna Intellectual Property, Inc. |
Systems and methods for generating and managing domain-based technology architecture
|
|
CA3222225A1
(en)
*
|
2021-06-03 |
2022-12-08 |
University Of Cincinnati |
Bzd-1 as a chemosensitizer of cancer
|
|
CN113244388A
(zh)
*
|
2021-07-01 |
2021-08-13 |
江苏先声药业有限公司 |
抗人vegf抗体与化药联用在制备治疗卵巢癌的药物中的应用
|
|
US11879010B2
(en)
|
2021-09-30 |
2024-01-23 |
The Charlotte Mecklenburg Hospital Authority |
Methods and compositions for pretargeted immunotherapy
|
|
CN114712377B
(zh)
*
|
2022-04-26 |
2023-08-15 |
江苏师范大学 |
断血流皂苷a在制造药物中的用途
|