NO20026094L - Kondenserte azepinderivater og deres anvendelse som antidiuretiske midler - Google Patents
Kondenserte azepinderivater og deres anvendelse som antidiuretiske midlerInfo
- Publication number
- NO20026094L NO20026094L NO20026094A NO20026094A NO20026094L NO 20026094 L NO20026094 L NO 20026094L NO 20026094 A NO20026094 A NO 20026094A NO 20026094 A NO20026094 A NO 20026094A NO 20026094 L NO20026094 L NO 20026094L
- Authority
- NO
- Norway
- Prior art keywords
- sup
- antidiuretic agents
- azepine derivatives
- condensed
- condensed azepine
- Prior art date
Links
- 229940124538 antidiuretic agent Drugs 0.000 title abstract 2
- 239000003160 antidiuretic agent Substances 0.000 title abstract 2
- 150000001538 azepines Chemical class 0.000 title abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 3
- GXBMIBRIOWHPDT-UHFFFAOYSA-N Vasopressin Natural products N1C(=O)C(CC=2C=C(O)C=CC=2)NC(=O)C(N)CSSCC(C(=O)N2C(CCC2)C(=O)NC(CCCN=C(N)N)C(=O)NCC(N)=O)NC(=O)C(CC(N)=O)NC(=O)C(CCC(N)=O)NC(=O)C1CC1=CC=CC=C1 GXBMIBRIOWHPDT-UHFFFAOYSA-N 0.000 abstract 1
- 102000002852 Vasopressins Human genes 0.000 abstract 1
- 108010004977 Vasopressins Proteins 0.000 abstract 1
- KBZOIRJILGZLEJ-LGYYRGKSSA-N argipressin Chemical compound C([C@H]1C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CSSC[C@@H](C(N[C@@H](CC=2C=CC(O)=CC=2)C(=O)N1)=O)N)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](CCCN=C(N)N)C(=O)NCC(N)=O)C1=CC=CC=C1 KBZOIRJILGZLEJ-LGYYRGKSSA-N 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 239000000018 receptor agonist Substances 0.000 abstract 1
- 229940044601 receptor agonist Drugs 0.000 abstract 1
- 229960003726 vasopressin Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
- C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D223/16—Benzazepines; Hydrogenated benzazepines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/12—Antidiuretics, e.g. drugs for diabetes insipidus
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
- C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
- C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
- C07D243/12—1,5-Benzodiazepines; Hydrogenated 1,5-benzodiazepines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D267/00—Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one oxygen atom as the only ring hetero atoms
- C07D267/02—Seven-membered rings
- C07D267/08—Seven-membered rings having the hetero atoms in positions 1 and 4
- C07D267/12—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
- C07D267/14—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems condensed with one six-membered ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D281/00—Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one sulfur atom as the only ring hetero atoms
- C07D281/02—Seven-membered rings
- C07D281/04—Seven-membered rings having the hetero atoms in positions 1 and 4
- C07D281/08—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
- C07D281/10—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems condensed with one six-membered ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0015601.8A GB0015601D0 (en) | 2000-06-26 | 2000-06-26 | Novel antidiuretic agents |
| PCT/GB2001/002737 WO2002000626A1 (en) | 2000-06-26 | 2001-06-21 | Fused azepine derivatives and their use as antidiuretic agents |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| NO20026094D0 NO20026094D0 (no) | 2002-12-18 |
| NO20026094L true NO20026094L (no) | 2003-02-24 |
| NO324217B1 NO324217B1 (no) | 2007-09-10 |
Family
ID=9894399
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20026094A NO324217B1 (no) | 2000-06-26 | 2002-12-18 | Kondenserte azepinderivater og deres anvendelse som antidiuretiske midler |
Country Status (21)
| Country | Link |
|---|---|
| US (1) | US7176195B2 (no) |
| EP (1) | EP1294698B1 (no) |
| JP (2) | JP3935071B2 (no) |
| KR (1) | KR100805808B1 (no) |
| CN (1) | CN1308313C (no) |
| AT (1) | ATE368650T1 (no) |
| AU (2) | AU2001274290B9 (no) |
| CA (1) | CA2412555A1 (no) |
| CZ (1) | CZ304037B6 (no) |
| DE (1) | DE60129697T2 (no) |
| GB (1) | GB0015601D0 (no) |
| HU (1) | HU229315B1 (no) |
| IL (1) | IL153358A0 (no) |
| MX (1) | MXPA02012779A (no) |
| NO (1) | NO324217B1 (no) |
| NZ (1) | NZ523066A (no) |
| PL (1) | PL359187A1 (no) |
| RU (1) | RU2269517C2 (no) |
| UA (1) | UA73177C2 (no) |
| WO (1) | WO2002000626A1 (no) |
| ZA (1) | ZA200300403B (no) |
Families Citing this family (35)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7138393B2 (en) | 1998-07-24 | 2006-11-21 | Wyeth | Biologically active vasopressin agonist metabolites |
| GB0000079D0 (en) * | 2000-01-05 | 2000-02-23 | Ferring Bv | Novel antidiuretic agents |
| GB0115515D0 (en) * | 2001-06-25 | 2001-08-15 | Ferring Bv | Oxytocin agonisys |
| GB0210397D0 (en) | 2002-05-07 | 2002-06-12 | Ferring Bv | Pharmaceutical formulations |
| EP2426122A1 (en) * | 2002-10-24 | 2012-03-07 | Merck Patent GmbH | Methylene urea derivative as RAF kinasse inhibitors |
| CA2511970C (en) | 2003-01-14 | 2012-06-26 | Cytokinetics, Inc. | Urea derivatives useful in the treatment of heart failure |
| US7700583B2 (en) | 2003-04-11 | 2010-04-20 | High Point Pharmaceuticals, Llc | 11β-hydroxysteroid dehydrogenase type 1 active compounds |
| ATE482747T1 (de) * | 2003-04-11 | 2010-10-15 | High Point Pharmaceuticals Llc | Neue amide derivate und deren pharmazeutische verwendungen |
| AU2004237778B2 (en) * | 2003-05-02 | 2008-08-14 | Worcester Polytechnic Institute | Composite gas separation modules having high tamman temperature intermediate layers |
| EP1512687A1 (en) * | 2003-09-05 | 2005-03-09 | Ferring B.V. | Piperazines as oxytocin agonists |
| ES2260563T3 (es) * | 2003-11-13 | 2006-11-01 | Ferring B.V. | Paquete de blister y forma farmaceutica solida para ello. |
| BRPI0512193B8 (pt) | 2004-06-17 | 2021-05-25 | Cytokinetics Inc | composto ou sal farmaceuticamente aceitável, composição farmacêutica, e, uso do composto ou sal |
| US7176222B2 (en) | 2004-07-27 | 2007-02-13 | Cytokinetics, Inc. | Syntheses of ureas |
| EP1627876A1 (en) * | 2004-08-20 | 2006-02-22 | Ferring B.V. | Heterocyclic condensed compounds useful as antidiuretic agents |
| EP1632494A1 (en) * | 2004-08-24 | 2006-03-08 | Ferring B.V. | Vasopressin v1a antagonists |
| JP4943858B2 (ja) * | 2004-11-17 | 2012-05-30 | キッセイ薬品工業株式会社 | 芳香族アミド誘導体、それを含有する医薬組成物およびそれらの医薬用途 |
| US7538223B2 (en) | 2005-08-04 | 2009-05-26 | Cytokinetics, Inc. | Compounds, compositions and methods |
| ES2419007T3 (es) | 2005-12-15 | 2013-08-19 | Cytokinetics, Inc. | Ciertas entidades químicas, composiciones y procedimientos |
| US7825120B2 (en) * | 2005-12-15 | 2010-11-02 | Cytokinetics, Inc. | Certain substituted ((piperazin-1-ylmethyl)benzyl)ureas |
| US7718657B2 (en) | 2005-12-16 | 2010-05-18 | Cytokinetics, Inc. | Certain indanyl urea modulators of the cardiac sarcomere |
| EP1962852B1 (en) * | 2005-12-19 | 2017-01-25 | Cytokinetics, Inc. | Compounds, compositions and methods |
| SE528446C2 (sv) * | 2006-03-02 | 2006-11-14 | Ferring Int Ct Sa | Farmaceutisk sammansättning innefattande desmopressin, kiseldioxid och stärkelse |
| CA2685860A1 (en) * | 2007-05-10 | 2008-11-20 | Amr Technology, Inc. | Aryl- and heteroaryl-substituted tetrahydrobenzo-1,4-diazepines and use thereof to block reuptake of norepinephrine, dopamine, and serotonin |
| KR20140143461A (ko) | 2007-08-06 | 2014-12-16 | 알레간 인코포레이티드 | 데스모프레신 약물 전달을 위한 방법 및 장치 |
| US11963995B2 (en) | 2008-05-21 | 2024-04-23 | Ferring B.V. | Methods comprising desmopressin |
| US20100286045A1 (en) | 2008-05-21 | 2010-11-11 | Bjarke Mirner Klein | Methods comprising desmopressin |
| SI2712622T1 (sl) * | 2008-05-21 | 2016-10-28 | Ferring B.V. | Orodisperzibilni dezmopresin za povečanje začetnega obdobja spanja nemotenega z nokturijo |
| GB201005623D0 (en) | 2010-04-01 | 2010-05-19 | Vantia Ltd | New polymorph |
| EP2681196B1 (en) * | 2011-03-04 | 2015-09-09 | Life Technologies Corporation | Compounds and methods for conjugation of biomolecules |
| GB201105537D0 (en) * | 2011-03-31 | 2011-05-18 | Vantia Ltd | New process |
| CN103159641A (zh) * | 2011-12-14 | 2013-06-19 | 天津泰普药品科技发展有限公司 | 托伐普坦中间体2-甲酸-5-(2-甲基苯甲酰氨基)甲苯的制备方法 |
| RU2480468C1 (ru) * | 2012-02-16 | 2013-04-27 | Открытое Акционерное Общество "Международная Научно-Технологическая Корпорация" | КРИСТАЛЛИЧЕСКАЯ МОДИФИКАЦИЯ ПАРА-МЕТОКСИАНИЛИДА 6-ГИДРОКСИ-4-ОКСО-2,4-ДИГИДРО-1Н-ПИРРОЛО[3,2,1-ij]ХИНОЛИН-5-КАРБОНОВОЙ КИСЛОТЫ |
| CN103373960B (zh) * | 2012-04-24 | 2017-03-01 | 江苏康缘药业股份有限公司 | 一种托伐普坦中间体及其制备方法 |
| WO2020154581A1 (en) * | 2019-01-24 | 2020-07-30 | Assia Chemical Industries Ltd | Solid state forms of fedovapagon-salicyclic acid co-crystal |
| WO2025003974A1 (en) | 2023-06-30 | 2025-01-02 | Chong Kun Dang Pharmaceutical Corp. | New preparation method of compound and new crystalline form |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL104853A (en) * | 1992-02-27 | 1997-11-20 | Yamanouchi Pharma Co Ltd | Benzodiazepine derivatives, their preparation and pharmaceutical compositions containing them |
| US5512563A (en) * | 1993-07-29 | 1996-04-30 | American Cyanamid Company | Tricyclic benzazepine vasopressin antagonists |
| US5516774A (en) | 1993-07-29 | 1996-05-14 | American Cyanamid Company | Tricyclic diazepine vasopressin antagonists and oxytocin antagonists |
| CA2192928C (en) | 1994-06-15 | 2010-10-26 | Hidenori Ogawa | Benzoheterocyclic derivatives |
| CN1183134C (zh) * | 1997-07-30 | 2005-01-05 | 惠氏公司 | 三环后叶加压素激动剂 |
| JP2001512120A (ja) * | 1997-07-30 | 2001-08-21 | アメリカン・ホーム・プロダクツ・コーポレイション | 三環系バソプレシンアゴニスト |
| GB2355454A (en) * | 1999-10-20 | 2001-04-25 | Ferring Bv | Antidiuretic agents |
| GB0000079D0 (en) * | 2000-01-05 | 2000-02-23 | Ferring Bv | Novel antidiuretic agents |
-
2000
- 2000-06-26 GB GBGB0015601.8A patent/GB0015601D0/en not_active Ceased
-
2001
- 2001-06-21 AU AU2001274290A patent/AU2001274290B9/en not_active Ceased
- 2001-06-21 MX MXPA02012779A patent/MXPA02012779A/es active IP Right Grant
- 2001-06-21 US US10/311,301 patent/US7176195B2/en not_active Expired - Fee Related
- 2001-06-21 HU HU0301339A patent/HU229315B1/hu not_active IP Right Cessation
- 2001-06-21 PL PL01359187A patent/PL359187A1/xx not_active IP Right Cessation
- 2001-06-21 RU RU2003101970/04A patent/RU2269517C2/ru not_active IP Right Cessation
- 2001-06-21 NZ NZ523066A patent/NZ523066A/en not_active IP Right Cessation
- 2001-06-21 CN CNB018118135A patent/CN1308313C/zh not_active Expired - Fee Related
- 2001-06-21 DE DE60129697T patent/DE60129697T2/de not_active Expired - Lifetime
- 2001-06-21 CA CA002412555A patent/CA2412555A1/en not_active Abandoned
- 2001-06-21 KR KR1020027017214A patent/KR100805808B1/ko not_active Expired - Fee Related
- 2001-06-21 AU AU7429001A patent/AU7429001A/xx active Pending
- 2001-06-21 IL IL15335801A patent/IL153358A0/xx unknown
- 2001-06-21 WO PCT/GB2001/002737 patent/WO2002000626A1/en not_active Ceased
- 2001-06-21 CZ CZ20024157A patent/CZ304037B6/cs not_active IP Right Cessation
- 2001-06-21 UA UA20021210560A patent/UA73177C2/uk unknown
- 2001-06-21 JP JP2002505374A patent/JP3935071B2/ja not_active Expired - Fee Related
- 2001-06-21 EP EP01940792A patent/EP1294698B1/en not_active Expired - Lifetime
- 2001-06-21 AT AT01940792T patent/ATE368650T1/de not_active IP Right Cessation
-
2002
- 2002-12-18 NO NO20026094A patent/NO324217B1/no not_active IP Right Cessation
-
2003
- 2003-01-15 ZA ZA200300403A patent/ZA200300403B/xx unknown
-
2005
- 2005-01-19 JP JP2005011930A patent/JP2005104990A/ja not_active Withdrawn
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| NO324217B1 (no) | Kondenserte azepinderivater og deres anvendelse som antidiuretiske midler | |
| IL151172A0 (en) | Amine derivatives, their preparation and use as bax modulators | |
| MXPA03004549A (es) | Derivados de 3-arilindola y su uso como agonistas del receptor cb2. | |
| DK1337518T3 (da) | Piperazinylpyrazinforbindelser som antagonister for serotonin-5-HT2-receptoren | |
| UY26754A1 (es) | Derivados de la 1, 3, 8, -triaza-spiro (4,5) decan-4-ona | |
| BR9803179A (pt) | Antagonistas receptores de ccr-3. | |
| SE0302760D0 (sv) | New compounds | |
| MXPA02012033A (es) | Derivados de 2-aminocarbonil-9h-purina. | |
| KR20050085991A (en) | Compounds exhibiting thrombopoietin receptor agonism | |
| AR029216A1 (es) | Compuestos inhibidores no peptidicos de la union celular dependiente de vla-4 utiles en el tratamiento de enfermedades inflamatorias, autoinmunes y respiratorias; composicion farmaceutica y procedimiento de tratamiento | |
| DK0889876T3 (da) | Meta-substituerede phenylensulfonamidderivater | |
| BRPI0111639B8 (pt) | uso de uma molécula de ácido oligodeoxinucléico imunoestimulatório e composição farmacêutica. | |
| CY1106076T1 (el) | Παραγωγα γλυκοπυρανοσυλοξυβενζυλο βενζολιου και ιατρικες συνθεσεις που πepιεχουν τα ιδια | |
| SE0201544D0 (sv) | Novel compounds and thier use | |
| PT1007523E (pt) | Derivados indole e 2,3-di-ridroindole, sua preparacao e utilizacao | |
| NO20025641D0 (no) | Substituerte 1-aminoalkyl-laktamer og deres anvendelse som muscarin-reseptor-antagonister | |
| BR0206595A (pt) | Composto, composição farmacêutica, e uso de um composto | |
| PA8495101A1 (es) | Derivados de 13-metileritromicina | |
| ATE291021T1 (de) | Oxytocin agonisten | |
| DK1778677T3 (da) | Heterocykliske kondenserede forbindelser der er egnede som antidiuretiske midler | |
| SE9901077D0 (sv) | Novel use | |
| BR0212353A (pt) | Composto, composição farmacêutica, e, uso de um composto | |
| ATE318810T1 (de) | 3-oxadiazol-5-yl-1-aminoalkyl-1h-indolderivate | |
| YU44301A (sh) | 5ht1 antagonisti za antidepresantnu terapiju | |
| MXPA04006113A (es) | Derivados de triazoloquinolina utiles como ligandos receptores de adenosina. |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MM1K | Lapsed by not paying the annual fees |