NO20026164L - Benzoksazepinoner og deres anvendelse som squalen syntase inhibitorer - Google Patents

Benzoksazepinoner og deres anvendelse som squalen syntase inhibitorer

Info

Publication number
NO20026164L
NO20026164L NO20026164A NO20026164A NO20026164L NO 20026164 L NO20026164 L NO 20026164L NO 20026164 A NO20026164 A NO 20026164A NO 20026164 A NO20026164 A NO 20026164A NO 20026164 L NO20026164 L NO 20026164L
Authority
NO
Norway
Prior art keywords
benzoxazepinones
synthase inhibitors
squalene synthase
squalene
inhibitors
Prior art date
Application number
NO20026164A
Other languages
English (en)
Other versions
NO20026164D0 (no
Inventor
Masakuni Kori
Takashi Miki
Tomoyuki Nishimoto
Ryuichi Tozawa
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Publication of NO20026164D0 publication Critical patent/NO20026164D0/no
Publication of NO20026164L publication Critical patent/NO20026164L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D267/00—Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D267/02—Seven-membered rings
    • C07D267/08—Seven-membered rings having the hetero atoms in positions 1 and 4
    • C07D267/12—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D267/14—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
NO20026164A 2000-06-23 2002-12-20 Benzoksazepinoner og deres anvendelse som squalen syntase inhibitorer NO20026164L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2000190253 2000-06-23
PCT/JP2001/005347 WO2001098282A1 (en) 2000-06-23 2001-06-22 Benzoxazepinones and their use as squalene synthase inhibitors

Publications (2)

Publication Number Publication Date
NO20026164D0 NO20026164D0 (no) 2002-12-20
NO20026164L true NO20026164L (no) 2002-12-20

Family

ID=18689751

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20026164A NO20026164L (no) 2000-06-23 2002-12-20 Benzoksazepinoner og deres anvendelse som squalen syntase inhibitorer

Country Status (16)

Country Link
US (1) US20030078251A1 (no)
EP (1) EP1292585A1 (no)
KR (1) KR20030011362A (no)
CN (1) CN1437587A (no)
AR (1) AR028974A1 (no)
AU (1) AU2001274588A1 (no)
BR (1) BR0111835A (no)
CA (1) CA2413429A1 (no)
CZ (1) CZ20024151A3 (no)
HU (1) HUP0301301A2 (no)
MX (1) MXPA02012481A (no)
NO (1) NO20026164L (no)
PL (1) PL360243A1 (no)
SK (1) SK17602002A3 (no)
WO (1) WO2001098282A1 (no)
ZA (1) ZA200209055B (no)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002038180A1 (en) * 2000-11-09 2002-05-16 Takeda Chemical Industries, Ltd. High-density lipoprotein-cholesterol level elevating agent
JP2004525109A (ja) 2001-02-15 2004-08-19 キング・ファーマシューティカルズ・インコーポレイティッド 安定化された甲状腺ホルモン医薬組成物、及びその製法
US20040204500A1 (en) * 2001-06-28 2004-10-14 Yasuo Sugiyama Preventives/remedies for organ functional disorders and organ dysfunction
US7101569B2 (en) 2001-08-14 2006-09-05 Franz G Andrew Methods of administering levothyroxine pharmaceutical compositions
EP1600166A4 (en) * 2003-01-17 2008-02-27 Takeda Pharmaceutical SKELETAL MUSCLE PROTECTIVE AGENT
EP1623710A1 (en) * 2003-04-18 2006-02-08 Takeda Pharmaceutical Company Limited Receptor antagonist
US7060698B2 (en) 2003-05-19 2006-06-13 Hoffmann-La Roche Inc. Benzoxazepinone derivatives
DE102004006325A1 (de) * 2004-02-10 2005-08-25 Bayer Healthcare Ag Tetrahydrobenzo[d]azepin-2-on-Derivate und ihre Verwendung
US20090118255A1 (en) * 2004-08-09 2009-05-07 Takeda Pharmaceutical Company Limited Crp Lowering Agent
AR054368A1 (es) * 2005-06-01 2007-06-20 Takeda Pharmaceutical Metodo para tratar hiperlipidemia
MX2011002793A (es) 2008-09-25 2011-04-05 Hoffmann La Roche Derivados de 3-amino-indazol o de 3-amino-4,5,6,7-tetrahidro-indaz ol.
US8921576B2 (en) 2011-10-19 2014-12-30 Kowa Company, Ltd. Spiroindoline compound, and medicinal agent comprising same
CN112274500A (zh) * 2020-10-30 2021-01-29 河南省儿童医院郑州儿童医院 单孢菌酸在制备抗凝血药物中的应用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SG82630A1 (en) * 1992-04-20 2001-08-21 Takeda Chemical Industries Ltd 4,1-benzoxazepin derivatives and their use
CN1072649C (zh) * 1995-09-13 2001-10-10 武田药品工业株式会社 苯并氧杂吖庚因化合物,其生产方法和用途

Also Published As

Publication number Publication date
SK17602002A3 (sk) 2003-06-03
CN1437587A (zh) 2003-08-20
BR0111835A (pt) 2003-04-29
WO2001098282A1 (en) 2001-12-27
MXPA02012481A (es) 2003-06-06
NO20026164D0 (no) 2002-12-20
AU2001274588A1 (en) 2002-01-02
KR20030011362A (ko) 2003-02-07
CZ20024151A3 (cs) 2003-05-14
US20030078251A1 (en) 2003-04-24
HUP0301301A2 (hu) 2003-08-28
AR028974A1 (es) 2003-05-28
EP1292585A1 (en) 2003-03-19
ZA200209055B (en) 2003-11-07
CA2413429A1 (en) 2001-12-27
PL360243A1 (en) 2004-09-06

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Legal Events

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FC2A Withdrawal, rejection or dismissal of laid open patent application