NO20030021L - Heterosykliske forbindelser som er inhibitorer for enzymet DPP-IV - Google Patents

Heterosykliske forbindelser som er inhibitorer for enzymet DPP-IV

Info

Publication number: NO20030021L
Authority: NO; Norway
Prior art keywords: dpp; inhibitors; heterocyclic compounds; enzyme dpp; compounds
Prior art date: 2000-07-04

Application number

NO20030021A

Other languages

English (en)

Norwegian (no)

Other versions

NO20030021D0 (no

Inventor

Anders Bendtz Kanstrup

Lise Brown Christiansen

Jane Marie Lundbeck

Christian K Sams

Marit Kristiansen

Original Assignee

Novo Nordisk As

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2000-07-04

Filing date

2003-01-03

Publication date

2003-03-03

2001-07-04 Priority claimed from PCT/DK2001/000467 external-priority patent/WO2002002560A2/en

2003-01-03 Application filed by Novo Nordisk As filed Critical Novo Nordisk As

2003-01-03 Publication of NO20030021D0 publication Critical patent/NO20030021D0/no

2003-03-03 Publication of NO20030021L publication Critical patent/NO20030021L/no

Links

108010067722 Dipeptidyl Peptidase 4 Proteins 0.000 title abstract 4
150000002391 heterocyclic compounds Chemical class 0.000 title 1
239000003112 inhibitor Substances 0.000 title 1
102100025012 Dipeptidyl peptidase 4 Human genes 0.000 abstract 2
208000008589 Obesity Diseases 0.000 abstract 2
150000001875 compounds Chemical class 0.000 abstract 2
201000010099 disease Diseases 0.000 abstract 2
208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 2
230000002779 inactivation Effects 0.000 abstract 2
235000020824 obesity Nutrition 0.000 abstract 2
102000004169 proteins and genes Human genes 0.000 abstract 2
108090000623 proteins and genes Proteins 0.000 abstract 2
208000001072 type 2 diabetes mellitus Diseases 0.000 abstract 2
229940124639 Selective inhibitor Drugs 0.000 abstract 1
239000003814 drug Substances 0.000 abstract 1
238000004519 manufacturing process Methods 0.000 abstract 1
238000000034 method Methods 0.000 abstract 1
239000008194 pharmaceutical composition Substances 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
- C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
- C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
- C07D473/06—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
- C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
- C07D473/06—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3
- C07D473/08—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3 with methyl radicals in positions 1 and 3, e.g. theophylline

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Diabetes (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Hematology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Obesity (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Emergency Medicine (AREA)
Endocrinology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

NO20030021A 2000-07-04 2003-01-03 Heterosykliske forbindelser som er inhibitorer for enzymet DPP-IV NO20030021L (no)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
DKPA200001040		2000-07-04
PCT/DK2001/000467 WO2002002560A2 (en)	2000-07-04	2001-07-04	Purine-2,6-diones which are inhibitors of the enzyme dipeptidyl peptidase iv (dpp-iv)

Publications (2)

Publication Number	Publication Date
NO20030021D0 NO20030021D0 (no)	2003-01-03
NO20030021L true NO20030021L (no)	2003-03-03

Family

ID=8159598

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO20030021A NO20030021L (no)	2000-07-04	2003-01-03	Heterosykliske forbindelser som er inhibitorer for enzymet DPP-IV

Country Status (13)

Country	Link
EP (1)	EP1561752A1 (cs)
KR (1)	KR20030014394A (cs)
CN (1)	CN1440288A (cs)
AT (1)	ATE299024T1 (cs)
BR (1)	BR0112123A (cs)
CA (1)	CA2411864A1 (cs)
CZ (1)	CZ200319A3 (cs)
DE (1)	DE60111849T2 (cs)
ES (1)	ES2244634T3 (cs)
IL (1)	IL153182A0 (cs)
NO (1)	NO20030021L (cs)
RU (1)	RU2003103103A (cs)
ZA (1)	ZA200209714B (cs)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CN102127057A (zh) *	2004-03-15	2011-07-20	武田药品工业株式会社	二肽基肽酶抑制剂
ATE553077T1 (de) *	2004-07-23	2012-04-15	Nuada Llc	Peptidaseinhibitoren
CN102276627B (zh) *	2010-04-29	2013-07-31	山东轩竹医药科技有限公司	吡啶并杂环衍生物
WO2012170702A1 (en)	2011-06-08	2012-12-13	Arena Pharmaceuticals, Inc.	Modulators of the gpr119 receptor and the treatment of disorders related thereto
CN103509023B (zh) *	2012-06-20	2014-08-27	成都苑东药业有限公司	黄嘌呤衍生物
CA2899646C (en)	2013-03-15	2021-08-31	Hydra Biosciences, Inc.	Substituted xanthines and methods of use thereof

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE2205815A1 (de) *	1972-02-08	1973-08-16	Hoechst Ag	Piperazinderivate und verfahren zu ihrer herstellung
GB9020959D0 (en) *	1990-09-26	1990-11-07	Beecham Group Plc	Novel compounds

2001
- 2001-07-04 CA CA002411864A patent/CA2411864A1/en not_active Abandoned
- 2001-07-04 CN CN01812097A patent/CN1440288A/zh active Pending
- 2001-07-04 CZ CZ200319A patent/CZ200319A3/cs unknown
- 2001-07-04 DE DE60111849T patent/DE60111849T2/de not_active Expired - Fee Related
- 2001-07-04 EP EP05008243A patent/EP1561752A1/en not_active Withdrawn
- 2001-07-04 RU RU2003103103/04A patent/RU2003103103A/ru not_active Application Discontinuation
- 2001-07-04 KR KR1020027017726A patent/KR20030014394A/ko not_active Withdrawn
- 2001-07-04 ES ES01947211T patent/ES2244634T3/es not_active Expired - Lifetime
- 2001-07-04 IL IL15318201A patent/IL153182A0/xx unknown
- 2001-07-04 AT AT01947211T patent/ATE299024T1/de not_active IP Right Cessation
- 2001-07-04 BR BR0112123-5A patent/BR0112123A/pt not_active IP Right Cessation
2002
- 2002-11-29 ZA ZA200209714A patent/ZA200209714B/xx unknown
2003
- 2003-01-03 NO NO20030021A patent/NO20030021L/no unknown

Also Published As

Publication number	Publication date
DE60111849D1 (de)	2005-08-11
NO20030021D0 (no)	2003-01-03
BR0112123A (pt)	2003-05-06
DE60111849T2 (de)	2006-06-08
EP1561752A1 (en)	2005-08-10
CZ200319A3 (cs)	2003-05-14
RU2003103103A (ru)	2004-08-20
CA2411864A1 (en)	2002-01-10
ES2244634T3 (es)	2005-12-16
IL153182A0 (en)	2003-06-24
CN1440288A (zh)	2003-09-03
ZA200209714B (en)	2003-08-19
ATE299024T1 (de)	2005-07-15
KR20030014394A (ko)	2003-02-17

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