NO20030471L - Karboksamidforbindelser og deres anvendelse som antagonister for en 11CBY-reseptor - Google Patents

Karboksamidforbindelser og deres anvendelse som antagonister for en 11CBY-reseptor

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Publication number
NO20030471L
NO20030471L NO20030471A NO20030471A NO20030471L NO 20030471 L NO20030471 L NO 20030471L NO 20030471 A NO20030471 A NO 20030471A NO 20030471 A NO20030471 A NO 20030471A NO 20030471 L NO20030471 L NO 20030471L
Authority
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Norway
Prior art keywords
optionally substituted
antagonists
heterocyclic ring
carboxamide compounds
hydroxyl
Prior art date
Application number
NO20030471A
Other languages
English (en)
Norwegian (no)
Other versions
NO20030471D0 (no
Inventor
Christopher Norbert Johnson
Martin Jones
Catherine Anne O'toole
Geoffrey Stemp
Kevin Michael Thewlis
David Witty
Original Assignee
Smithkline Beecham Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB0018758.3A external-priority patent/GB0018758D0/en
Priority claimed from GB0112544A external-priority patent/GB0112544D0/en
Application filed by Smithkline Beecham Plc filed Critical Smithkline Beecham Plc
Publication of NO20030471D0 publication Critical patent/NO20030471D0/no
Publication of NO20030471L publication Critical patent/NO20030471L/no

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    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/08—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms
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    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
    • C07D295/135—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
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    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/14—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D295/155—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
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    • C07D317/48—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
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    • C07D317/60—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
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NO20030471A 2000-07-31 2003-01-30 Karboksamidforbindelser og deres anvendelse som antagonister for en 11CBY-reseptor NO20030471L (no)

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GBGB0018758.3A GB0018758D0 (en) 2000-07-31 2000-07-31 Novel use and compunds
GB0112544A GB0112544D0 (en) 2001-05-23 2001-05-23 Novel use and compounds
PCT/EP2001/008637 WO2002010146A1 (fr) 2000-07-31 2001-07-26 Composes du carboxamide et leur utilisation comme antagonistes d'un recepteur 11cby humain

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GB0625523D0 (en) * 2006-12-21 2007-01-31 Ge Healthcare Ltd In vivo imaging agents
TWI417100B (zh) 2007-06-07 2013-12-01 Astrazeneca Ab 二唑衍生物及其作為代謝型麩胺酸受體增效劑-８４２之用途
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PE20091928A1 (es) 2008-05-29 2009-12-31 Bristol Myers Squibb Co Tienopirimidinas hidroxisustituidas como antagonistas de receptor-1 de hormona concentradora de melanina no basicos
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HUP0302966A2 (hu) 2003-12-29
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BG107510A (bg) 2003-09-30
EA200300064A1 (ru) 2003-06-26
AP2003002720A0 (en) 2003-06-30
OA12346A (en) 2004-04-13
SK1142003A3 (en) 2003-06-03
CZ2003297A3 (cs) 2003-05-14
MXPA03000923A (es) 2003-06-09
CA2417638A1 (fr) 2002-02-07
CN1444573A (zh) 2003-09-24
JP2004505070A (ja) 2004-02-19
KR20030059084A (ko) 2003-07-07
AU2001278508A1 (en) 2002-02-13
EP1305304A1 (fr) 2003-05-02

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