NO20032101D0 - Apoliprotein analoger - Google Patents
Apoliprotein analogerInfo
- Publication number
- NO20032101D0 NO20032101D0 NO20032101A NO20032101A NO20032101D0 NO 20032101 D0 NO20032101 D0 NO 20032101D0 NO 20032101 A NO20032101 A NO 20032101A NO 20032101 A NO20032101 A NO 20032101A NO 20032101 D0 NO20032101 D0 NO 20032101D0
- Authority
- NO
- Norway
- Prior art keywords
- apoliprotein
- analogues
- apoliprotein analogues
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/775—Apolipopeptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/47—Hydrolases (3) acting on glycosyl compounds (3.2), e.g. cellulases, lactases
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/02—Antidotes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/62—DNA sequences coding for fusion proteins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
- C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/20—Fusion polypeptide containing a tag with affinity for a non-protein ligand
- C07K2319/21—Fusion polypeptide containing a tag with affinity for a non-protein ligand containing a His-tag
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/31—Fusion polypeptide fusions, other than Fc, for prolonged plasma life, e.g. albumin
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/50—Fusion polypeptide containing protease site
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
- C07K2319/73—Fusion polypeptide containing domain for protein-protein interaction containing coiled-coiled motif (leucine zippers)
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Zoology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Gastroenterology & Hepatology (AREA)
- Wood Science & Technology (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Toxicology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Plant Pathology (AREA)
- Immunology (AREA)
- Physics & Mathematics (AREA)
- Epidemiology (AREA)
- Microbiology (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Diabetes (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DKPA200001682 | 2000-11-10 | ||
| DKPA200100057 | 2001-01-15 | ||
| US26402201P | 2001-01-26 | 2001-01-26 | |
| PCT/DK2001/000739 WO2002038609A2 (en) | 2000-11-10 | 2001-11-09 | Apolipoprotein conjugates |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| NO20032101D0 true NO20032101D0 (no) | 2003-05-09 |
| NO20032101L NO20032101L (no) | 2003-07-08 |
| NO331274B1 NO331274B1 (no) | 2011-11-14 |
Family
ID=27222453
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20032101A NO331274B1 (no) | 2000-11-10 | 2003-05-09 | Apolipoproteinanaloger |
Country Status (10)
| Country | Link |
|---|---|
| US (4) | US6897039B2 (no) |
| EP (2) | EP2343317A1 (no) |
| JP (2) | JP4344136B2 (no) |
| CN (1) | CN1268641C (no) |
| AU (2) | AU2002213843B2 (no) |
| BR (1) | BR0115257A (no) |
| CA (1) | CA2428114C (no) |
| CY (1) | CY1111118T1 (no) |
| NO (1) | NO331274B1 (no) |
| WO (1) | WO2002038609A2 (no) |
Families Citing this family (83)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR100330355B1 (ko) * | 1999-06-04 | 2002-04-01 | 장인순 | 회전유동발생 날개를 가진 덕트형 핵연료 집합체 지지격자 |
| AU2002232642B2 (en) * | 2000-12-12 | 2007-02-01 | Lexicon Pharmaceuticals, Inc. | Novel human kinases and uses thereof |
| AU2002249893B2 (en) | 2001-01-02 | 2007-05-24 | The Cleveland Clinic Foundation | Myeloperoxidase, a risk indicator for cardiovascular disease |
| AU2002362612B2 (en) * | 2001-09-28 | 2007-11-15 | Cedars-Sinai Medical Center | Prevention and treatment of restenosis by local administration of drug |
| WO2004069795A2 (en) * | 2003-02-03 | 2004-08-19 | Pfizer Products Inc. | Diagnosis and treatment of chronic tissue damage |
| EP2314285B2 (en) | 2003-02-14 | 2019-09-18 | Children's Hospital & Research Center at Oakland | Lipophilic drug delivery vehicle and methods of use thereof |
| KR20050120663A (ko) * | 2003-03-24 | 2005-12-22 | 세쿠오이아 파마큐티컬스 인코오퍼레이티드 | 장기간 작용하는 생물학적 활동 컨쥬게이트들 |
| KR20050114283A (ko) * | 2003-04-22 | 2005-12-05 | 아바니르 파마슈티컬스 | 고콜레스테롤혈증을 치료하기 위한 역 콜레스테롤 수송의매개제 |
| EP1618135B1 (en) | 2003-04-23 | 2013-06-26 | F.Hoffmann-La Roche Ag | Cleavage of fusion proteins using granzyme b protease |
| US7459286B1 (en) * | 2003-10-22 | 2008-12-02 | The Cleveland Clinic Foundation | Assessing the risk of a major adverse cardiac event in patients with chest pain |
| EP2306192B1 (en) | 2003-12-05 | 2015-10-14 | The Cleveland Clinic Foundation | Risk Markers For Cardiovascular Disease |
| US20050176623A1 (en) * | 2004-02-11 | 2005-08-11 | Neil Wagle | Non-invasive treatment of disease using amphipathic compounds |
| US20100028995A1 (en) * | 2004-02-23 | 2010-02-04 | Anaphore, Inc. | Tetranectin Trimerizing Polypeptides |
| JP2007531537A (ja) * | 2004-04-06 | 2007-11-08 | セダーズ−シナイ メディカル センター | アポリポタンパク質a−iおよびアポリポタンパク質a−imilanoをコードする組換えアデノ随伴ウイルスベクターによる血管疾患の予防および処置 |
| KR100560102B1 (ko) * | 2004-06-25 | 2006-03-13 | 한국생명공학연구원 | 프로아포리포단백질 a-ⅰ 변이체와, 이를 포함하는고지혈증 또는 동맥경화증 예방 및 치료제 |
| US7378396B2 (en) * | 2004-08-11 | 2008-05-27 | The Cleveland Clinic Foundation | Therapeutic agents and methods for cardiovascular disease |
| AU2006282722A1 (en) * | 2005-08-26 | 2007-03-01 | Cerenis Therapeutics Holdings S.A. | Compositions and methods for producing apolipoprotein gene products in lactic acid bacteria |
| US20080248565A1 (en) * | 2007-03-01 | 2008-10-09 | Invitrogen Corporation | Isolated phospholipid-protein particles |
| US20070117179A1 (en) * | 2005-09-27 | 2007-05-24 | Invitrogen Corporation | In vitro protein synthesis systems for membrane proteins that include adolipoproteins and phospholipid-adolipoprotein particles |
| US20140113860A1 (en) | 2006-02-03 | 2014-04-24 | Prolor Biotech Ltd. | Long-acting polypeptides and methods of producing and administering same |
| US10221228B2 (en) | 2006-02-03 | 2019-03-05 | Opko Biologics Ltd. | Long-acting polypeptides and methods of producing and administering same |
| US9249407B2 (en) | 2006-02-03 | 2016-02-02 | Opko Biologics Ltd. | Long-acting coagulation factors and methods of producing same |
| US9458444B2 (en) | 2006-02-03 | 2016-10-04 | Opko Biologics Ltd. | Long-acting coagulation factors and methods of producing same |
| US8946155B2 (en) | 2006-02-03 | 2015-02-03 | Opko Biologics Ltd. | Long-acting polypeptides and methods of producing and administering same |
| US8048849B2 (en) | 2006-02-03 | 2011-11-01 | Modigene, Inc. | Long-acting polypeptides and methods of producing same |
| US20150038413A1 (en) | 2006-02-03 | 2015-02-05 | Opko Biologics Ltd. | Long-acting polypeptides and methods of producing and administering same |
| US10351615B2 (en) | 2006-02-03 | 2019-07-16 | Opko Biologics Ltd. | Methods of treatment with long-acting growth hormone |
| US7534595B2 (en) * | 2006-06-12 | 2009-05-19 | Biomarin Pharmaceutical Inc. | Compositions of prokaryotic phenylalanine ammonia-lyase and methods of using compositions thereof |
| US20110201548A1 (en) * | 2007-04-23 | 2011-08-18 | Nihon Pharmaceutical Co., Ltd. | Therapeutic agent for acute hepatitis or prophylactic/therapeutic agent for fulminant hepatitis |
| WO2009048961A1 (en) * | 2007-10-08 | 2009-04-16 | Anaphore, Inc. | Trimeric il-1ra |
| WO2009097587A2 (en) * | 2008-01-30 | 2009-08-06 | The Rockefeller University | Nanoscale bound bilayers, methods of use and production |
| WO2009158678A1 (en) | 2008-06-27 | 2009-12-30 | Children's Hospital & Research Center At Oakland | Lipophilic nucleic acid delivery vehicle and methods of use therefor |
| US8734853B2 (en) * | 2008-11-17 | 2014-05-27 | University Of North Texas Health Science Center At Fort Worth | HDL particles for delivery of nucleic acids |
| US20120157380A1 (en) * | 2009-06-05 | 2012-06-21 | Nan Wang | Pegylated human apoa-1 and process for production thereof |
| US12203113B2 (en) | 2009-07-09 | 2025-01-21 | Opko Biologics Ltd. | Long-acting coagulation factors and methods of producing same |
| US9663778B2 (en) | 2009-07-09 | 2017-05-30 | OPKO Biologies Ltd. | Long-acting coagulation factors and methods of producing same |
| US12419839B2 (en) | 2009-10-09 | 2025-09-23 | Signablok, Inc. | Methods and compositions for targeted delivery of protein fragments |
| US10894098B2 (en) | 2012-04-09 | 2021-01-19 | Signablok, Inc. | Methods and compositions for targeted imaging |
| US10525152B2 (en) | 2009-10-09 | 2020-01-07 | Signablok, Inc. | Methods and compositions for targeted imaging |
| AU2010329805B2 (en) * | 2009-12-11 | 2016-07-14 | Proyecto De Biomedicina Cima S.L. | New conjugates and compositions for immunotherapy and anti-tumoral treatment |
| JP2013531990A (ja) * | 2010-06-15 | 2013-08-15 | シー. ローヤー,マシュー | アテローム性動脈硬化症治療のための組成物および方法 |
| CN101923093B (zh) * | 2010-07-13 | 2013-12-18 | 昆明理工大学 | 树鼩IgG的三抗体夹心ELISA检测方法 |
| EP2611419A2 (en) * | 2010-08-30 | 2013-07-10 | F.Hoffmann-La Roche Ag | Method for producing a tetranectin-apolipoprotein a-1 lipid particle, the lipid particle itself and its use |
| BR112013004396A2 (pt) * | 2010-08-30 | 2016-05-17 | Hoffmann La Roche | alimentação alcalina |
| CN103068369A (zh) * | 2010-08-30 | 2013-04-24 | 霍夫曼-拉罗奇有限公司 | 产生四连蛋白-载脂蛋白a-i颗粒的方法,由此获得的脂质颗粒及其应用 |
| EP2611921A2 (en) * | 2010-08-30 | 2013-07-10 | F.Hoffmann-La Roche Ag | Prokaryotic expression construct |
| US20120190609A1 (en) * | 2010-08-30 | 2012-07-26 | Martin Bader | Method for producing a lipid particle, the lipid particle itself and its use |
| MX2013002145A (es) | 2010-08-30 | 2013-04-03 | Hoffmann La Roche | Tetranectina-apolipoproteina a-i, particulas lipidicas que la contienen y utilizacion de la misma. |
| EP2673296B1 (en) * | 2011-02-07 | 2018-10-24 | Cerenis Therapeutics Holding SA | Lipoprotein complexes and manufacturing and uses thereof |
| BR112013033562A2 (pt) | 2011-08-25 | 2017-02-14 | Hoffmann La Roche | proteína de fusão de tetranectina-apolipoproteína a-i encurtada, uma partícula de lipídio que a contém e uso das mesmas |
| CN103703015B (zh) * | 2011-08-25 | 2019-07-05 | 霍夫曼-拉罗奇有限公司 | 阳离子和阴离子交换层析法 |
| PL2793913T3 (pl) * | 2011-12-21 | 2023-11-06 | Csl Limited | Schemat dawkowania dla formulacji apolipoproteiny |
| WO2013125769A1 (ko) * | 2012-02-24 | 2013-08-29 | 성균관대학교 산학협력단 | 아포리포단백질을 포함하는 항체-약물 결합체 |
| KR101536037B1 (ko) * | 2012-02-24 | 2015-07-13 | 성균관대학교산학협력단 | 아포리포단백질을 포함하는 항체-약물 결합체 |
| BR112014025951A2 (pt) | 2012-04-19 | 2017-07-11 | Opko Biologics Ltd | variantes de oxintomodulina de longa ação e métodos de produção do mesmo |
| WO2014023315A1 (en) * | 2012-08-10 | 2014-02-13 | Aarhus Universitet | Multimerization through beta-strand swapping in ccp domains |
| EA033788B1 (ru) | 2012-11-20 | 2019-11-26 | Opko Biologics Ltd | Способ увеличения гидродинамического объема полипептида путем присоединения карбоксиконцевого пептида гонадотропина |
| EP3004160B1 (en) * | 2013-06-05 | 2022-12-28 | CSL Limited | Process for preparing apolipoprotein a-i (apo a-i) |
| EP2853259A1 (en) | 2013-09-30 | 2015-04-01 | Université Pierre et Marie Curie (Paris 6) | Reconstituted high density lipoproteins composition and uses thereof |
| US20150158926A1 (en) | 2013-10-21 | 2015-06-11 | Opko Biologics, Ltd. | Long-acting polypeptides and methods of producing and administering same |
| WO2015173633A2 (en) | 2014-05-02 | 2015-11-19 | Cerenis Therapeutics Holding Sa | Hdl therapy markers |
| US10961286B2 (en) | 2014-08-15 | 2021-03-30 | Cornell University | Nucleic acids, vectors, host cells, and methods for recombinantly producing water-soluble membrane proteins |
| HRP20230405T8 (hr) | 2014-12-10 | 2023-09-29 | Opko Biologics Ltd. | Metode proizvodnje dugo djelujućih ctp-modificiranih polipeptida hormona rasta |
| ES2893616T3 (es) | 2015-06-19 | 2022-02-09 | Opko Biologics Ltd | Factores de coagulación de acción prolongada y métodos para la producción de los mismos |
| WO2017044424A1 (en) | 2015-09-08 | 2017-03-16 | Theripion, Inc. | Apoa-1 fusion polypeptides and related compositions and methods |
| MY206271A (en) | 2016-07-11 | 2024-12-06 | Opko Biologics Ltd | Long-acting coagulation factor vii and methods of producing same |
| WO2018136163A2 (en) * | 2016-12-09 | 2018-07-26 | Theripion, Inc. | Tandem apoa-1 fusion polypeptides |
| WO2019030574A1 (en) | 2017-08-10 | 2019-02-14 | Cerenis Therapeutics Holding | Cargomers |
| ES2984286T3 (es) | 2017-08-10 | 2024-10-29 | Abionyx Pharma Sa | Apómeros |
| CA3074593A1 (en) * | 2017-09-08 | 2019-03-14 | The University Of Bristol | Protein delivery to membranes |
| KR20230004605A (ko) | 2020-04-16 | 2023-01-06 | 아비오닉스 파마 에스에이 | 지질 결합 단백질-기반 복합체를 사용하여 급성 상태를 치료하는 방법 |
| MX2023003877A (es) | 2020-10-01 | 2023-04-18 | Abionyx Pharma Sa | Composiciones que comprenden complejos basados en proteina de union a lipidos para usarse en el tratamiento de enfermedades oculares. |
| KR20240018430A (ko) | 2021-04-15 | 2024-02-13 | 아비오닉스 파마 에스에이 | 기관 보존 용액에서의 지질 결합 단백질-기반 복합체의 사용 |
| CN114940711B (zh) * | 2021-10-25 | 2023-05-12 | 中山大学 | 载脂蛋白a-i模拟肽及其应用 |
| AU2023250345A1 (en) | 2022-04-06 | 2024-11-14 | Abionyx Pharma Sa | Methods for treating eye diseases using lipid binding protein-based complexes |
| CA3247588A1 (en) | 2022-04-06 | 2023-10-12 | Abionyx Pharma Sa | METHODS FOR TREATING LEUKOCYTOSIS, ENDOTHELIAL DYSFUNCTION AND CARDITIS USING LIPID-BINDING PROTEIN COMPLEXES |
| WO2023237927A2 (en) | 2022-06-10 | 2023-12-14 | Abionyx Pharma Sa | Methods for treating hyperinflammatory conditions using lipid binding protein -based complexes |
| JP2025519606A (ja) | 2022-06-10 | 2025-06-26 | アビオニクス ファーマ エスエー | 脂質結合タンパク質に基づく複合体を使用して急性状態を処置するための方法 |
| CN115290776A (zh) * | 2022-07-26 | 2022-11-04 | 云南大学 | 瘤牛锥虫病抗性蛋白的应用 |
| WO2024150064A1 (en) | 2023-01-13 | 2024-07-18 | Abionyx Pharma Sa | Lipid binding protein molecule therapy |
| WO2025093929A1 (en) | 2023-10-31 | 2025-05-08 | Abionyx Pharma Sa | Lipid binding protein molecule therapy |
| WO2025175130A1 (en) * | 2024-02-16 | 2025-08-21 | The Children's Medical Center Corporation | Apom fusion constructs and methods of use in treating inflammatory diseases |
| CN119823289B (zh) * | 2025-03-20 | 2025-06-10 | 内蒙古和讯生物科技有限公司 | 一种蛋白基生物材料及其制备方法与应用 |
Family Cites Families (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4970144A (en) * | 1984-12-31 | 1990-11-13 | International Genetic Engineering | Peptide fragments of human apolipoprotein, type-specific antibodies and methods of use |
| US5068045A (en) * | 1985-08-27 | 1991-11-26 | Mobil Oil Corporation | Grease composition containing alkoxylated amide borates |
| GB8625435D0 (en) * | 1986-10-23 | 1986-11-26 | Erba Farmitalia | Human apolipoprotein ai |
| US5128318A (en) * | 1987-05-20 | 1992-07-07 | The Rogosin Institute | Reconstituted HDL particles and uses thereof |
| US5534617A (en) * | 1988-10-28 | 1996-07-09 | Genentech, Inc. | Human growth hormone variants having greater affinity for human growth hormone receptor at site 1 |
| IT1229996B (it) | 1989-04-20 | 1991-09-20 | Cesare Sirtori | Espressione di apolipoproteina ai e apolipoproteina ai-milano in lievito e composizioni farmaceutiche che contengono dette apolipoproteine. |
| US5182364A (en) * | 1990-02-26 | 1993-01-26 | The Scripps Research Institute | Polypeptide analogs of apolipoprotein E |
| US5177189A (en) * | 1989-08-18 | 1993-01-05 | The Scripps Research Institute | Polypeptide analogs of Apolipoprotein E |
| US5473039A (en) * | 1989-08-18 | 1995-12-05 | The Scripps Research Institute | Polypeptide analogs of apolipoprotein E, diagnostic systems and methods using the analogs |
| AU9088891A (en) * | 1990-11-29 | 1992-06-25 | John E. Carbaugh | Diagnostic and therapeutic compositions and methods for lipoprotein(a) |
| WO1993000077A1 (en) | 1991-06-21 | 1993-01-07 | University Of Cincinnati | Orally administrable therapeutic proteins and method of making |
| WO1993000443A1 (en) * | 1991-06-26 | 1993-01-07 | Bio-Technology General Corp. | Purification of recombinant apolipoprotein e from bacteria |
| US5408038A (en) * | 1991-10-09 | 1995-04-18 | The Scripps Research Institute | Nonnatural apolipoprotein B-100 peptides and apolipoprotein B-100-apolipoprotein A-I fusion peptides |
| US5716805A (en) * | 1991-10-25 | 1998-02-10 | Immunex Corporation | Methods of preparing soluble, oligomeric proteins |
| SE9103701D0 (sv) | 1991-12-13 | 1991-12-13 | Kabi Pharmacia Ab | Apolipoprotein |
| WO1994004563A1 (fr) * | 1992-08-14 | 1994-03-03 | Shino-Test Corporation | PEPTIDES CONTENANT DES SEQUENCES D'ACIDES AMINES RESPECTIVES SELECTIONNEES PARMI CELLES DE LA LIPOPROTEINE(a) ET DE L'APOLIPOPROTEINE(a), ANTICORPS RECONNAISSANT CES SEQUENCES D'ACIDES AMINES ET PROCEDE D'ANALYSE UTILISANT CES ANTICORPS |
| SE9203753D0 (sv) | 1992-12-11 | 1992-12-11 | Kabi Pharmacia Ab | Expression system for producing apolipoprotein ai-m |
| ATE143803T1 (de) | 1992-12-22 | 1996-10-15 | Univ Cincinnati | Orale verabreichung von immunologischen aktiven biomolekülen und anderen therapeutischen proteinen |
| CA2155335C (en) | 1993-02-04 | 2001-06-05 | HANS CHRISTIAN THõGERSEN | Improved method for the refolding of proteins |
| SE9300937L (sv) | 1993-03-19 | 1994-09-20 | Anne Fjellestad Paulsen | Komposition för oral administrering av peptider |
| FR2704556B1 (fr) * | 1993-04-30 | 1995-07-13 | Rhone Poulenc Rorer Sa | Virus recombinants et leur utilisation en thérapie génique. |
| US5643757A (en) | 1994-03-21 | 1997-07-01 | American Cyanamid Company | High yield production of human apolipoprotein A1 in E. coli. |
| GB9409768D0 (en) | 1994-05-16 | 1994-07-06 | Medical Res Council | Trimerising polypeptides |
| SE9500778D0 (sv) | 1995-03-03 | 1995-03-03 | Pharmacia Ab | Process for producing a protein |
| FR2734568B1 (fr) | 1995-05-22 | 1997-06-20 | Rhone Poulenc Rorer Sa | Nouveaux variants de l'apolipoproteine |
| CA2230492C (en) * | 1995-09-21 | 2009-05-26 | Genentech, Inc. | Human growth hormone variants |
| US5922680A (en) | 1996-10-23 | 1999-07-13 | Ferring, B.V. | Stabilized composition for oral administration of peptides |
| AU736707B2 (en) | 1997-06-11 | 2001-08-02 | Anaphore, Inc. | Trimerising module |
| US6004925A (en) * | 1997-09-29 | 1999-12-21 | J. L. Dasseux | Apolipoprotein A-I agonists and their use to treat dyslipidemic disorders |
| JP4394279B2 (ja) | 1998-03-09 | 2010-01-06 | ジーランド ファーマ アクティーゼルスカブ | 酵素加水分解に対する傾向が減少した薬理学的に活性なペプチド複合体 |
-
2001
- 2001-11-09 EP EP10177657A patent/EP2343317A1/en not_active Withdrawn
- 2001-11-09 CA CA2428114A patent/CA2428114C/en not_active Expired - Fee Related
- 2001-11-09 CN CNB018218504A patent/CN1268641C/zh not_active Expired - Fee Related
- 2001-11-09 BR BR0115257-2A patent/BR0115257A/pt active Search and Examination
- 2001-11-09 EP EP01982197A patent/EP1335938B1/en not_active Expired - Lifetime
- 2001-11-09 AU AU2002213843A patent/AU2002213843B2/en not_active Ceased
- 2001-11-09 JP JP2002541940A patent/JP4344136B2/ja not_active Expired - Fee Related
- 2001-11-09 WO PCT/DK2001/000739 patent/WO2002038609A2/en not_active Ceased
- 2001-11-09 AU AU1384302A patent/AU1384302A/xx active Pending
- 2001-11-13 US US09/987,107 patent/US6897039B2/en not_active Expired - Fee Related
-
2003
- 2003-05-09 NO NO20032101A patent/NO331274B1/no not_active IP Right Cessation
-
2004
- 2004-12-21 US US11/017,037 patent/US20050096277A1/en not_active Abandoned
- 2004-12-21 US US11/017,059 patent/US20050142639A1/en not_active Abandoned
-
2008
- 2008-12-01 US US12/325,384 patent/US20090136467A1/en not_active Abandoned
- 2008-12-25 JP JP2008330674A patent/JP2009118849A/ja active Pending
-
2010
- 2010-11-29 CY CY20101101089T patent/CY1111118T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP1335938B1 (en) | 2010-09-22 |
| CY1111118T1 (el) | 2015-06-11 |
| JP2009118849A (ja) | 2009-06-04 |
| CA2428114C (en) | 2013-07-23 |
| JP2004522424A (ja) | 2004-07-29 |
| CA2428114A1 (en) | 2002-05-16 |
| US20090136467A1 (en) | 2009-05-28 |
| US20020156007A1 (en) | 2002-10-24 |
| EP2343317A1 (en) | 2011-07-13 |
| CN1268641C (zh) | 2006-08-09 |
| BR0115257A (pt) | 2003-08-12 |
| WO2002038609A2 (en) | 2002-05-16 |
| AU1384302A (en) | 2002-05-21 |
| WO2002038609A3 (en) | 2002-09-26 |
| AU2002213843A2 (en) | 2002-05-21 |
| NO20032101L (no) | 2003-07-08 |
| JP4344136B2 (ja) | 2009-10-14 |
| CN1486327A (zh) | 2004-03-31 |
| EP1335938A2 (en) | 2003-08-20 |
| US6897039B2 (en) | 2005-05-24 |
| NO331274B1 (no) | 2011-11-14 |
| US20050142639A1 (en) | 2005-06-30 |
| AU2002213843B2 (en) | 2008-02-07 |
| US20050096277A1 (en) | 2005-05-05 |
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