NO20032904D0 - Natriumkanal-modulatorer utledet fra 2-piperidylimidazoler - Google Patents

Natriumkanal-modulatorer utledet fra 2-piperidylimidazoler

Info

Publication number
NO20032904D0
NO20032904D0 NO20032904A NO20032904A NO20032904D0 NO 20032904 D0 NO20032904 D0 NO 20032904D0 NO 20032904 A NO20032904 A NO 20032904A NO 20032904 A NO20032904 A NO 20032904A NO 20032904 D0 NO20032904 D0 NO 20032904D0
Authority
NO
Norway
Prior art keywords
piperidylimidazoles
sodium channel
channel modulators
modulators derived
derived
Prior art date
Application number
NO20032904A
Other languages
English (en)
Norwegian (no)
Other versions
NO20032904L (no
Inventor
Dennis Bigg
Jacques Pommier
Anne-Marie Liberatore
Original Assignee
Sod Conseils Rech Applic
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sod Conseils Rech Applic filed Critical Sod Conseils Rech Applic
Publication of NO20032904L publication Critical patent/NO20032904L/no
Publication of NO20032904D0 publication Critical patent/NO20032904D0/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • A61K31/4523Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/454Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4151,2-Diazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/06Antimigraine agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/08Antiepileptics; Anticonvulsants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/06Antiarrhythmics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Epidemiology (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Rheumatology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
NO20032904A 2000-12-28 2003-06-24 Natriumkanal-modulatorer utledet fra 2-piperidylimidazoler NO20032904D0 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0017149A FR2818978B1 (fr) 2000-12-28 2000-12-28 Modulateurs de canaux sodiques derives de 2-piperidylimidazoles
PCT/FR2001/004209 WO2002053559A1 (fr) 2000-12-28 2001-12-27 Modulateurs de canaux sodiques derives de 2-piperidylimidazoles

Publications (2)

Publication Number Publication Date
NO20032904L NO20032904L (no) 2003-06-24
NO20032904D0 true NO20032904D0 (no) 2003-06-24

Family

ID=8858291

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20032904A NO20032904D0 (no) 2000-12-28 2003-06-24 Natriumkanal-modulatorer utledet fra 2-piperidylimidazoler

Country Status (24)

Country Link
US (1) US20040077640A1 (de)
EP (1) EP1349850B1 (de)
JP (1) JP2004517121A (de)
KR (1) KR100892656B1 (de)
CN (1) CN1214025C (de)
AR (1) AR035613A1 (de)
AT (1) ATE304005T1 (de)
AU (1) AU2002228128B8 (de)
BR (1) BR0116581A (de)
CA (1) CA2432959A1 (de)
CZ (1) CZ20032053A3 (de)
DE (1) DE60113297T2 (de)
DK (1) DK1349850T3 (de)
ES (1) ES2249488T3 (de)
FR (1) FR2818978B1 (de)
HU (1) HUP0600032A2 (de)
IL (1) IL156352A0 (de)
MX (1) MXPA03005914A (de)
NO (1) NO20032904D0 (de)
NZ (1) NZ526394A (de)
PL (1) PL363640A1 (de)
RU (1) RU2275369C2 (de)
WO (1) WO2002053559A1 (de)
ZA (1) ZA200305005B (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2008001596A (ja) * 2004-09-03 2008-01-10 Astellas Pharma Inc ナトリウムチャネル阻害剤
EP1963280B1 (de) * 2005-12-22 2015-10-28 Newron Pharmaceuticals S.p.A. 2-phenylethylaminoderivate als calcium- und/oder natrium-kanalmodulatoren
JPWO2007111323A1 (ja) 2006-03-27 2009-08-13 東レ株式会社 ウレイド誘導体およびその医薬用途
DE102007047243A1 (de) 2007-09-25 2009-04-02 Karl Storz Gmbh & Co. Kg Bipolares medizinisches Instrument
JP5529044B2 (ja) * 2008-01-25 2014-06-25 イー・アイ・デュポン・ドウ・ヌムール・アンド・カンパニー 殺菌性複素環化合物
WO2025122832A1 (en) * 2023-12-07 2025-06-12 Genep Inc. Imidazole compounds and their use as sodium channel inhibitors

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SK118794A3 (en) * 1992-04-01 1995-06-07 Univ Toledo 4(4'-piperidinyl or 3'- pyrrolidinyl) substitutes imidazoles as h3-receptor
US5296609A (en) * 1993-04-09 1994-03-22 Syntex Pharmaceuticals, Ltd. Process for the preparation of 1,2,4-substituted imidazoles and related aminoalkylimidazole derivatives
CN1088062C (zh) * 1994-11-23 2002-07-24 纽罗根公司 某些4-氨基甲基-2-取代的咪唑衍生物2-氨基甲基-4-取代的咪唑衍生物新的一族多巴胺受体亚型特异性配体
DE69637948D1 (de) * 1995-10-06 2009-07-23 Merck & Co Inc Substituierte imidazole mit krebsremmender und cytokininhibierender wirkung
EP0906307B1 (de) * 1996-06-10 2005-04-27 Merck & Co., Inc. Substituierte imidazole mit cytokinin-inhibirender wirkung
ES2188184T3 (es) * 1998-06-12 2003-06-16 Sod Conseils Rech Applic Compuestos de beta-carbolinas.
ES2345921T3 (es) * 1999-03-26 2010-10-06 Euro-Celtique S.A. Pirazoles, imidazoles, oxazoles, tiazoles y pirroles sustituidos con arilo y su uso.
US6297256B1 (en) * 1999-06-15 2001-10-02 Neurogen Corporation Aryl and heteroaryl substituted pyridino derivatives GABA brain receptor ligands
TWI283577B (en) * 1999-10-11 2007-07-11 Sod Conseils Rech Applic Pharmaceutical composition of imidazole derivatives acting as modulators of sodium channels and the use thereof
IL149872A0 (en) * 1999-12-16 2002-11-10 Schering Corp Substituted imidazole neuropeptide y y5 receptor antagonists

Also Published As

Publication number Publication date
DE60113297T2 (de) 2006-07-13
EP1349850B1 (de) 2005-09-07
RU2275369C2 (ru) 2006-04-27
FR2818978B1 (fr) 2003-02-28
RU2003123119A (ru) 2005-01-10
CN1214025C (zh) 2005-08-10
HK1059784A1 (en) 2004-07-16
CA2432959A1 (fr) 2002-07-11
PL363640A1 (en) 2004-11-29
AU2002228128B2 (en) 2006-08-03
NZ526394A (en) 2004-12-24
ES2249488T3 (es) 2006-04-01
IL156352A0 (en) 2004-01-04
AR035613A1 (es) 2004-06-16
ZA200305005B (en) 2004-06-28
AU2002228128B8 (en) 2007-01-04
US20040077640A1 (en) 2004-04-22
NO20032904L (no) 2003-06-24
KR100892656B1 (ko) 2009-04-15
WO2002053559A1 (fr) 2002-07-11
MXPA03005914A (es) 2003-09-10
FR2818978A1 (fr) 2002-07-05
DK1349850T3 (da) 2006-01-23
DE60113297D1 (de) 2005-10-13
CZ20032053A3 (en) 2004-04-14
CN1483029A (zh) 2004-03-17
KR20030070592A (ko) 2003-08-30
BR0116581A (pt) 2004-01-06
ATE304005T1 (de) 2005-09-15
EP1349850A1 (de) 2003-10-08
JP2004517121A (ja) 2004-06-10
HUP0600032A2 (en) 2006-06-28
AU2002228128A1 (en) 2002-07-16

Similar Documents

Publication Publication Date Title
DE50107622D1 (de) Wellendichtring
ATA6032000A (de) Dichtring-kombination
DE60114391D1 (de) Kanaltrennungsabschirmung
DE60125769D1 (de) Verbessertes elektroentionisierungssystem
DE50105294D1 (de) Dichtungsprofil
FI20001068L (fi) Telekommunikaatiojärjestelmä
DE50108256D1 (de) Dichtungsanordnung
NO20010884D0 (no) Tetningssammenstillinger
DE60142878D1 (de) Gleitringdichtung
DE60118495D1 (de) Doppeldichtung
DE60122247D1 (de) Optischer Multiplexer/Demultiplexer
DE60113246D1 (de) Dichtring
DE50110228D1 (de) Gleitringdichtung
NO20032075D0 (no) Rammer for riggtang
DE10196859T1 (de) Verbesserte Dichtung
IT250181Y1 (it) Custodia perfezionata per rivoltella
DE50110340D1 (de) Splittergefechtskopf zur bekämpfung technischer ziele
DE50010600D1 (de) Dichtungsanordnung
NO20023661D0 (no) Kvadruppelkabel
NO20032904L (no) Natriumkanal-modulatorer utledet fra 2-piperidylimidazoler
DE50107252D1 (de) Flachdichtung
IT1316081B1 (it) Trappola per muridi
DK1134424T3 (da) Tætningshus
EP1501790A4 (de) Neue natriumkanalblocker
DE50107702D1 (de) Zylinderdeckeldichtung

Legal Events

Date Code Title Description
FC2A Withdrawal, rejection or dismissal of laid open patent application