NO20033883L - Heterosykliske derivater for behandling av kreft og andre proliferative sykdommer - Google Patents
Heterosykliske derivater for behandling av kreft og andre proliferative sykdommerInfo
- Publication number
- NO20033883L NO20033883L NO20033883A NO20033883A NO20033883L NO 20033883 L NO20033883 L NO 20033883L NO 20033883 A NO20033883 A NO 20033883A NO 20033883 A NO20033883 A NO 20033883A NO 20033883 L NO20033883 L NO 20033883L
- Authority
- NO
- Norway
- Prior art keywords
- cancer
- treatment
- proliferative diseases
- heterocyclic derivatives
- heterocyclic
- Prior art date
Links
- 206010028980 Neoplasm Diseases 0.000 title 1
- 201000011510 cancer Diseases 0.000 title 1
- 201000010099 disease Diseases 0.000 title 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title 1
- 125000000623 heterocyclic group Chemical group 0.000 title 1
- 230000002062 proliferating effect Effects 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/34—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Hematology (AREA)
- Oncology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US27475101P | 2001-03-07 | 2001-03-07 | |
| PCT/US2002/007001 WO2002072009A2 (fr) | 2001-03-07 | 2002-03-07 | Derives heterocycliques pour le traitement du cancer et d'autres maladies proliferatives |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| NO20033883D0 NO20033883D0 (no) | 2003-09-02 |
| NO20033883L true NO20033883L (no) | 2003-11-05 |
Family
ID=23049469
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20033883A NO20033883L (no) | 2001-03-07 | 2003-09-02 | Heterosykliske derivater for behandling av kreft og andre proliferative sykdommer |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US7153875B2 (fr) |
| EP (1) | EP1385465A4 (fr) |
| JP (1) | JP2005506290A (fr) |
| AU (1) | AU2002252227A1 (fr) |
| BR (1) | BR0207846A (fr) |
| CA (1) | CA2440184A1 (fr) |
| EA (1) | EA200300982A1 (fr) |
| IL (1) | IL157740A0 (fr) |
| MX (1) | MXPA03008117A (fr) |
| NO (1) | NO20033883L (fr) |
| PL (1) | PL373912A1 (fr) |
| WO (1) | WO2002072009A2 (fr) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BR0013671A (pt) | 1999-08-31 | 2003-06-10 | Maxia Pharmaceuticals Inc | Derivados heterocìclicos para o tratamento do diabetes e outras doenças |
| WO2002072009A2 (fr) | 2001-03-07 | 2002-09-19 | Maxia Pharmaceuticals, Inc. | Derives heterocycliques pour le traitement du cancer et d'autres maladies proliferatives |
| JP2004523571A (ja) | 2001-03-08 | 2004-08-05 | マキシア・ファーマシューティカルズ・インコーポレイテッド | Rxr活性化分子 |
| JP2005500379A (ja) * | 2001-08-17 | 2005-01-06 | インサイト サンディエゴ インコーポレーテッド | 異脂肪血症および高コレステロール血症を治療するオキシム誘導体 |
| EP1456187A4 (fr) * | 2001-11-15 | 2005-02-09 | Incyte San Diego Inc | Heterocycles n-substitues pour le traitement de l'hypercholesterolemie, de la dyslipidemie et autres troubles du metabolisme, du cancer et de pathologies diverses |
| CN100348569C (zh) | 2001-11-30 | 2007-11-14 | 伯哈姆学院 | 癌细胞中编程性细胞死亡的诱导 |
| US7102000B2 (en) * | 2002-03-08 | 2006-09-05 | Incyte San Diego Inc. | Heterocyclic amide derivatives for the treatment of diabetes and other diseases |
| US7196108B2 (en) * | 2002-03-08 | 2007-03-27 | Incyte San Diego Inc. | Bicyclic heterocycles for the treatment of diabetes and other diseases |
| CA2520172C (fr) * | 2003-03-27 | 2012-10-02 | Lankenau Institute For Medical Research | Nouvelles methodes pour le traitement du cancer avec un inhibiteur de l'indoleamine-2,3-dioxygenase |
| FR2856401B1 (fr) * | 2003-06-20 | 2010-02-12 | Galderma Res & Dev | Nouveaux composes modulateurs des recepteurs de type ppargamma et leur utilisation dans des compositions cosmetiques ou pharmaceutiques |
| DE10351744A1 (de) * | 2003-10-31 | 2005-06-16 | Schering Ag | Thiazolidinone, deren Herstellung und Verwendung als Arzneimittel |
| US7122700B2 (en) | 2004-07-30 | 2006-10-17 | Xerox Corporation | Arylamine processes |
| FR2884248B1 (fr) * | 2005-04-08 | 2007-05-18 | Galderma Res & Dev | Nouveau procede de preparation de l'acide 6-[3-(1-adamantyl)-4-methoxyphenyl]-2-naphtoique |
| KR101280779B1 (ko) * | 2005-04-08 | 2013-07-05 | 갈데르마 리써어치 앤드 디벨로프먼트 | 6-(3-(1-아다만틸)-4-메톡시페닐)-2-나프토산의 신규 제조방법 |
| KR100814109B1 (ko) | 2006-01-09 | 2008-03-14 | 한국생명공학연구원 | 로다닌 유도체, 이의 제조방법 및 이를 유효성분으로함유하는 약학적 조성물 |
| TW200815429A (en) * | 2006-04-11 | 2008-04-01 | Smithkline Beecham Corp | Thiazolidinedione derivatives as PI3 kinase inhibitors |
| US20080255115A1 (en) * | 2007-04-11 | 2008-10-16 | Michael Gerard Darcy | Thiazolidinedione derivatives as pi3 kinase inhibitors |
| PE20090288A1 (es) * | 2007-05-10 | 2009-04-03 | Smithkline Beecham Corp | Derivados de quinoxalina como inhibidores de la pi3 quinasa |
| PE20090717A1 (es) * | 2007-05-18 | 2009-07-18 | Smithkline Beecham Corp | Derivados de quinolina como inhibidores de la pi3 quinasa |
| EP2674417A3 (fr) | 2007-11-21 | 2014-04-09 | Decode Genetics EHF | Inhibiteurs de pde4 biaryle pour le traitement de l'inflammation |
| AU2008326381B2 (en) * | 2007-11-21 | 2014-10-23 | Decode Genetics Ehf | Biaryl PDE4 inhibitors for treating inflammation |
| CN102558088A (zh) * | 2010-12-31 | 2012-07-11 | 中国科学院上海药物研究所 | 联苯亚甲基-2-硫代-4-噻唑酮类化合物及其制备方法和用途 |
| KR102922092B1 (ko) * | 2021-12-21 | 2026-02-03 | 주식회사 메디픽바이오 | 치환된 티아졸리딘디온 유도체 화합물 및 이를 포함하는 암의 예방 또는 치료용 약학적 조성물 |
| US20250066347A1 (en) * | 2021-12-21 | 2025-02-27 | Medific, Inc. | Substituted thiazolidinedione derivative compound, and pharmaceutical composition for preventing or treating cancer, comprising same |
| US12115148B1 (en) | 2024-05-10 | 2024-10-15 | Imam Mohammad Ibn Saud Islamic University | 3-(2-(1,3-dioxoisoindolin-2-yl)ethyl)-5-(2-hydroxy-5-nitrobenzylidene)thiazolidine-2,4-dione as a potential antitumor and apoptotic inducer |
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|---|---|---|---|---|
| US4051842A (en) | 1975-09-15 | 1977-10-04 | International Medical Corporation | Electrode and interfacing pad for electrical physiological systems |
| DE2626348C3 (de) | 1976-06-11 | 1980-01-31 | Siemens Ag, 1000 Berlin Und 8000 Muenchen | Implantierbare Dosiereinrichtung |
| JPS5538359A (en) | 1978-09-12 | 1980-03-17 | Hamari Yakuhin Kogyo Kk | Preparation of 2-(3-benzoylphenyl)-propionic acid |
| US4383529A (en) | 1980-11-03 | 1983-05-17 | Wescor, Inc. | Iontophoretic electrode device, method and gel insert |
| IL72684A (en) | 1984-08-14 | 1989-02-28 | Israel State | Pharmaceutical compositions for controlled transdermal delivery of cholinergic or anticholinergic basic drugs |
| US4713244A (en) | 1985-08-16 | 1987-12-15 | Bausch & Lomb Incorporated | Sustained-release formulation containing an amino acid polymer with a lower alkyl (C1 -C4) polar solvent |
| US4931279A (en) | 1985-08-16 | 1990-06-05 | Bausch & Lomb Incorporated | Sustained release formulation containing an ion-exchange resin |
| US4668506A (en) | 1985-08-16 | 1987-05-26 | Bausch & Lomb Incorporated | Sustained-release formulation containing and amino acid polymer |
| CA1325222C (fr) | 1985-08-23 | 1993-12-14 | Lederle (Japan), Ltd. | Procede pour la production d'acide 4-biphenylylacetique |
| US4971996A (en) | 1987-03-11 | 1990-11-20 | Kanegafuchi Kagaku Kogyo Kabushiki Kaisha | Hydroxystyrene compounds which are useful as tyrosine kinase inhibitors |
| FI91869C (fi) * | 1987-03-18 | 1994-08-25 | Tanabe Seiyaku Co | Menetelmä antidiabeettisena aineena käytettävien bensoksatsolijohdannaisten valmistamiseksi |
| US5223522A (en) | 1988-03-08 | 1993-06-29 | Pfizer Inc. | Thiazolidinedione hypoglycemic agents |
| US5330998A (en) | 1988-03-08 | 1994-07-19 | Pfizer Inc. | Thiazolidinedione derivatives as hypoglycemic agents |
| IE940525L (en) | 1988-05-25 | 1989-11-25 | Warner Lambert Co | Known and selected novel arylmethylenyl derivatives of¹thiazolidinones, imidazolidinones and oxazolidinones useful¹as antiallergy agents and antiinflammatory agents |
| ES2123562T3 (es) | 1991-07-22 | 1999-01-16 | Pfizer | Procedimiento para la preparacion de (s)-4-(3-(5-metil-2-fenil-4-oxazolil)-1-hidroxipropil)bromobenceno. |
| BR9306284A (pt) | 1992-04-22 | 1998-01-13 | Ligand Pharm Inc | Compostos tendo seletividade pra receptores de retinóides x |
| US5780676A (en) | 1992-04-22 | 1998-07-14 | Ligand Pharmaceuticals Incorporated | Compounds having selective activity for Retinoid X Receptors, and means for modulation of processes mediated by Retinoid X Receptors |
| CZ181493A3 (en) | 1992-09-10 | 1994-03-16 | Lilly Co Eli | The use of rhodanine derivative for the preparation of a pharmaceutical composition reducing level of sugar in blood and for treating alzheimer's disease |
| AU700706B2 (en) | 1992-11-25 | 1999-01-14 | Ligand Pharmaceuticals, Inc. | RXR homodimer formation and bridged bicyclic aromatic compounds and their use in modulating gene expression |
| US5691376A (en) | 1994-02-17 | 1997-11-25 | American Home Products Corporation | Substituted biphenyl derivatives |
| JPH09510191A (ja) | 1994-02-17 | 1997-10-14 | アメリカン・ホーム・プロダクツ・コーポレイション | ホスホジエステラーゼ阻害薬としての置換ビフェニル誘導体 |
| JPH09136877A (ja) | 1995-06-16 | 1997-05-27 | Takeda Chem Ind Ltd | 複素環化合物、その製造法及び用途 |
| CA2223489A1 (fr) | 1995-07-17 | 1997-02-06 | Joseph A. Fontana | Procedes de traitement de cancers a l'aide de 6-¬3-¬1-adamantyl|-4-hydroxyphenyl| |
| CN1196730A (zh) | 1996-06-19 | 1998-10-21 | 雷迪博士研究基金会 | 具有增强的抗糖尿病活性的穴糖酮的新的多晶型形式及其制备方法 |
| RU2209626C2 (ru) | 1996-07-08 | 2003-08-10 | Галдерма Ресерч энд Девелопмент, С.Н.С. | Производные адамантила, вызывающие апоптоз, и их использование в качестве противораковых агентов |
| EP1007038A2 (fr) | 1997-08-21 | 2000-06-14 | Takeda Chemical Industries, Ltd. | Agent antiinflammatoire |
| US5972986A (en) * | 1997-10-14 | 1999-10-26 | G.D. Searle & Co. | Method of using cyclooxygenase-2 inhibitors in the treatment and prevention of neoplasia |
| JP4398585B2 (ja) | 1997-11-12 | 2010-01-13 | 有限会社ケムフィズ | レチノイドレセプター作用剤 |
| US6262044B1 (en) | 1998-03-12 | 2001-07-17 | Novo Nordisk A/S | Modulators of protein tyrosine phosphatases (PTPASES) |
| US6331633B1 (en) | 1998-05-08 | 2001-12-18 | Calyx Therapeutics Inc. | Heterocyclic analogs of diphenylethylene compounds |
| ID27787A (id) | 1998-08-21 | 2001-04-26 | Viro Pharma Inc | Senyawa, komposisi dan metode untuk pengobatan atau pencegahan infeksi yang disebabkan oleh virus dan penyakit-penyakit yang berkaitan |
| WO2000018748A1 (fr) | 1998-09-30 | 2000-04-06 | Roche Diagnostics Gmbh | Derives de rhodanine utiles pour le traitement et la prevention de troubles metaboliques des os |
| WO2000032598A1 (fr) | 1998-12-04 | 2000-06-08 | Structural Bioinformatics Inc. | Methodes et compositions destines au traitement de maladiesnflammatoires a base d'inhibiteurs de l'activite du facteur de necrose tumorale |
| WO2000063196A1 (fr) | 1999-04-20 | 2000-10-26 | Novo Nordisk A/S | Nouveaux composes, leur preparation et leur utilisation |
| US6462032B1 (en) | 1999-05-04 | 2002-10-08 | Wyeth | Cyclic regimens utilizing indoline derivatives |
| BR0013671A (pt) | 1999-08-31 | 2003-06-10 | Maxia Pharmaceuticals Inc | Derivados heterocìclicos para o tratamento do diabetes e outras doenças |
| KR100608416B1 (ko) | 1999-11-12 | 2006-08-02 | 후지모토 쿄다이 가부시키가이샤 | 2-(n-시아노이미노)티아졸리딘-4-온 유도체 |
| FR2812876B1 (fr) | 2000-08-08 | 2002-09-27 | Galderma Res & Dev | Nouveaux composes bi-aromatiques activateurs des recepteurs de type ppar-gamma et leur utilisation dans des compositions cosmetiques ou pharmaceutiques |
| WO2002072009A2 (fr) | 2001-03-07 | 2002-09-19 | Maxia Pharmaceuticals, Inc. | Derives heterocycliques pour le traitement du cancer et d'autres maladies proliferatives |
| JP2004523571A (ja) | 2001-03-08 | 2004-08-05 | マキシア・ファーマシューティカルズ・インコーポレイテッド | Rxr活性化分子 |
| CA2438586A1 (fr) | 2001-03-14 | 2002-09-19 | Eli Lilly And Company | Modulateurs des recepteurs x de retinoides |
| CA2443325C (fr) | 2001-04-04 | 2011-06-14 | Ortho-Mcneil Pharmaceutical, Inc. | Polytherapie comprenant des inhibiteurs de reabsorption du glucose et des modulateurs du recepteur x du retinoide |
| JP2005500379A (ja) | 2001-08-17 | 2005-01-06 | インサイト サンディエゴ インコーポレーテッド | 異脂肪血症および高コレステロール血症を治療するオキシム誘導体 |
| EP1456187A4 (fr) | 2001-11-15 | 2005-02-09 | Incyte San Diego Inc | Heterocycles n-substitues pour le traitement de l'hypercholesterolemie, de la dyslipidemie et autres troubles du metabolisme, du cancer et de pathologies diverses |
| AR037714A1 (es) | 2001-12-06 | 2004-12-01 | Maxia Pharmaceuticals Inc | Derivados de tiazolidinona y oxazolidinona 2-sustituidos para la inhibicion de fosfatasas y el tratamiento de cancer |
| US7102000B2 (en) | 2002-03-08 | 2006-09-05 | Incyte San Diego Inc. | Heterocyclic amide derivatives for the treatment of diabetes and other diseases |
| US7196108B2 (en) | 2002-03-08 | 2007-03-27 | Incyte San Diego Inc. | Bicyclic heterocycles for the treatment of diabetes and other diseases |
| JP4638423B2 (ja) * | 2003-06-20 | 2011-02-23 | ガルデルマ・リサーチ・アンド・デヴェロップメント | PPARγタイプ受容体を調節する新規化合物および化粧品組成物または医薬品組成物へのその使用 |
-
2002
- 2002-03-07 WO PCT/US2002/007001 patent/WO2002072009A2/fr not_active Ceased
- 2002-03-07 BR BR0207846-5A patent/BR0207846A/pt not_active Application Discontinuation
- 2002-03-07 EP EP02721289A patent/EP1385465A4/fr not_active Withdrawn
- 2002-03-07 PL PL02373912A patent/PL373912A1/xx not_active Application Discontinuation
- 2002-03-07 IL IL15774002A patent/IL157740A0/xx unknown
- 2002-03-07 JP JP2002570969A patent/JP2005506290A/ja active Pending
- 2002-03-07 MX MXPA03008117A patent/MXPA03008117A/es unknown
- 2002-03-07 CA CA002440184A patent/CA2440184A1/fr not_active Abandoned
- 2002-03-07 EA EA200300982A patent/EA200300982A1/ru unknown
- 2002-03-07 US US10/094,142 patent/US7153875B2/en not_active Expired - Fee Related
- 2002-03-07 AU AU2002252227A patent/AU2002252227A1/en not_active Abandoned
-
2003
- 2003-09-02 NO NO20033883A patent/NO20033883L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| EP1385465A2 (fr) | 2004-02-04 |
| CA2440184A1 (fr) | 2002-09-19 |
| MXPA03008117A (es) | 2004-11-12 |
| EP1385465A4 (fr) | 2005-09-07 |
| PL373912A1 (en) | 2005-09-19 |
| BR0207846A (pt) | 2005-09-13 |
| WO2002072009A3 (fr) | 2003-10-16 |
| US7153875B2 (en) | 2006-12-26 |
| US20020143182A1 (en) | 2002-10-03 |
| JP2005506290A (ja) | 2005-03-03 |
| IL157740A0 (en) | 2004-03-28 |
| NO20033883D0 (no) | 2003-09-02 |
| AU2002252227A1 (en) | 2002-09-24 |
| EA200300982A1 (ru) | 2004-12-30 |
| WO2002072009A2 (fr) | 2002-09-19 |
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