NO20034029L - Substituerte dimetyl-[1-(1-fenyl-cykloheksyl)-piperidin-3-yl metyl]-aminerog anvendelse derav som analgetika - Google Patents

Substituerte dimetyl-[1-(1-fenyl-cykloheksyl)-piperidin-3-yl metyl]-aminerog anvendelse derav som analgetika

Info

Publication number
NO20034029L
NO20034029L NO20034029A NO20034029A NO20034029L NO 20034029 L NO20034029 L NO 20034029L NO 20034029 A NO20034029 A NO 20034029A NO 20034029 A NO20034029 A NO 20034029A NO 20034029 L NO20034029 L NO 20034029L
Authority
NO
Norway
Prior art keywords
piperidin
ylmethyl
phenylcyclohexyl
analgesics
amine
Prior art date
Application number
NO20034029A
Other languages
English (en)
Norwegian (no)
Other versions
NO20034029D0 (no
Inventor
Michael Sattlegger
Elke Reissmueller
Original Assignee
Gruenenthal Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gruenenthal Gmbh filed Critical Gruenenthal Gmbh
Publication of NO20034029D0 publication Critical patent/NO20034029D0/no
Publication of NO20034029L publication Critical patent/NO20034029L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/40—Oxygen atoms
    • C07D211/44—Oxygen atoms attached in position 4
    • C07D211/48—Oxygen atoms attached in position 4 having an acyclic carbon atom attached in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/40—Oxygen atoms
    • C07D211/44—Oxygen atoms attached in position 4
    • C07D211/46—Oxygen atoms attached in position 4 having a hydrogen atom as the second substituent in position 4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A61P29/02—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] without antiinflammatory effect
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D211/26—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D211/70—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pain & Pain Management (AREA)
  • Public Health (AREA)
  • Rheumatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
NO20034029A 2001-03-14 2003-09-11 Substituerte dimetyl-[1-(1-fenyl-cykloheksyl)-piperidin-3-yl metyl]-aminerog anvendelse derav som analgetika NO20034029L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10112198A DE10112198A1 (de) 2001-03-14 2001-03-14 Substituierte Dimethyl-[1-(1-phenyl-cyclohexyl)-piperidin-3-ylmethyl]-amine
PCT/EP2002/002723 WO2002072550A1 (de) 2001-03-14 2002-03-13 Substituierte dimethyl`1-(1-phenyl-cyclohexyl)-piperidin-3-ylmethyl!-amine und verwendung als analgetika

Publications (2)

Publication Number Publication Date
NO20034029D0 NO20034029D0 (no) 2003-09-11
NO20034029L true NO20034029L (no) 2003-11-13

Family

ID=7677392

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20034029A NO20034029L (no) 2001-03-14 2003-09-11 Substituerte dimetyl-[1-(1-fenyl-cykloheksyl)-piperidin-3-yl metyl]-aminerog anvendelse derav som analgetika

Country Status (23)

Country Link
US (1) US7049327B2 (cs)
EP (1) EP1370529B1 (cs)
JP (1) JP2004526726A (cs)
KR (1) KR20040012733A (cs)
CN (1) CN1496352A (cs)
AT (1) ATE315551T1 (cs)
BR (1) BR0208243A (cs)
CA (1) CA2440758A1 (cs)
CZ (1) CZ20032455A3 (cs)
DE (2) DE10112198A1 (cs)
DK (1) DK1370529T3 (cs)
EC (1) ECSP034768A (cs)
ES (1) ES2256499T3 (cs)
HU (1) HUP0302800A2 (cs)
IL (1) IL157893A0 (cs)
MX (1) MXPA03007967A (cs)
NO (1) NO20034029L (cs)
PE (1) PE20020926A1 (cs)
PL (1) PL364415A1 (cs)
RU (1) RU2003129061A (cs)
SK (1) SK11122003A3 (cs)
WO (1) WO2002072550A1 (cs)
ZA (1) ZA200307964B (cs)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105646332B (zh) * 2014-11-09 2018-05-25 复旦大学 氨基甲基哌啶类衍生物及其制备方法和药物用途
KR102603671B1 (ko) * 2017-01-17 2023-11-17 메비아스 디스커버리 인코포레이티드 치환된 3-디알킬아미노메틸-피페리딘-4-일-벤즈아미드 및 이를 제조 및 사용하는 방법

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL40064A0 (en) * 1972-08-07 1972-10-29 Univ Tel Aviv Phencyclidine and its derivatives as short-time acting midriatics
WO1998055478A1 (fr) * 1997-06-03 1998-12-10 Societe De Conseils De Recherches Et D'applications Scientifiques (S.C.R.A.S.) Nouveaux derives de phencyclidines, des procedes pour leur preparation et des compositions pharmaceutiques les contenant
US4598153A (en) * 1984-12-19 1986-07-01 The United States Of America As Represented By The Department Of Health And Human Services Metaphit, a specific acylating agent for the [3 H] phencyclidine
US5155212A (en) * 1986-05-21 1992-10-13 Abbott Laboratories Phencyclidine and phencyclidine metabolites assay, tracers, immunogens, antibodies and reagent kit
HUT77318A (hu) * 1994-09-30 1998-03-30 Novartis Ag. 1-Acil-4-/(alifás amino)-piperidin/-származékok, e vegyületeket tartalmazó gyógyszerkészítmények, eljárás előállításukra és alkalmazásuk
ID29137A (id) * 1998-07-27 2001-08-02 Schering Corp Ligan-ligan afinitas tinggi untuk reseptor nosiseptin orl-1
DE10000312A1 (de) * 2000-01-05 2001-07-12 Gruenenthal Gmbh Substituierte Aminomethyl-Phenyl-Cyclohexanderivate

Also Published As

Publication number Publication date
SK11122003A3 (sk) 2004-01-08
ATE315551T1 (de) 2006-02-15
NO20034029D0 (no) 2003-09-11
CZ20032455A3 (cs) 2003-12-17
KR20040012733A (ko) 2004-02-11
PE20020926A1 (es) 2002-10-26
ES2256499T3 (es) 2006-07-16
MXPA03007967A (es) 2004-10-15
RU2003129061A (ru) 2005-04-10
JP2004526726A (ja) 2004-09-02
PL364415A1 (en) 2004-12-13
US20040127516A1 (en) 2004-07-01
DE50205593D1 (de) 2006-04-06
DE10112198A1 (de) 2002-09-19
CN1496352A (zh) 2004-05-12
HUP0302800A2 (hu) 2003-11-28
EP1370529B1 (de) 2006-01-11
IL157893A0 (en) 2004-03-28
ZA200307964B (en) 2004-09-14
DK1370529T3 (da) 2006-05-22
EP1370529A1 (de) 2003-12-17
US7049327B2 (en) 2006-05-23
CA2440758A1 (en) 2002-09-19
ECSP034768A (es) 2003-10-28
BR0208243A (pt) 2004-03-09
WO2002072550A1 (de) 2002-09-19

Similar Documents

Publication Publication Date Title
HRP20070374T3 (en) Formulations comprising ecteinascidin and a disaccharide
WO2004082623A3 (en) Substituted piperidine compounds
NO20072839L (no) 4-hydroksybenzomorfaner
PL375344A1 (en) Novel carboxamide compounds having an mch-antagonistic effect, medicaments containing said compounds, and methods for the production thereof
AU2003273179A1 (en) 1,1-disubstituted cycloalkyl derivatives as factor xa inhibitors
NO20021450D0 (no) Cykliske aminforbindelser som CCR5 antagonister
AU2003289440A1 (en) Nitrogen-containing heterocycic derivatives, medicinal compositions containing the same and medicinal use thereof
PL376373A1 (en) Selected cgrp antagonists, method for production and use thereof as medicament
PL376450A1 (en) Selected cgrp antagonists, method for production and use thereof as medicament
AU2003237958A8 (en) Composition containing at least one silicone-polyamide structured oil and a gelling agent, and methods of the use thereof
ATE509010T1 (de) 2, 4, 6-phenylsubstituierte cyclische ketoenole
ZA200410408B (en) N-substituted piperidine derivatives as serotonin receptor agents.
IL162669A0 (en) Antichlinergic agents, method for producing the same and use thereof as medicaments
ATE319684T1 (de) Sulfonamidderivate, deren herstellung und deren verwendung als medikamente
ATE397933T1 (de) Kristallinform gamma-d von ivabradine- hydrochlorid, verfahren zu dessen herstellung und diesen enthaltende pharmazeutische zusammensetzung
HUP0300002A3 (en) Substituted piperidines, medicaments containing these compounds, and methods for the production thereof
DK1581518T3 (da) Substituerede 1-piperidin-4-yl-4-pyrrolidin-3-yl-piperazin-derivater og deres anvendelse som neurokinin antagonister
EP2394992A3 (en) Substituted piperidine compounds and methods of their use
HUP0500137A2 (en) Pyrrolidine-2-ones as factor xa inhibitors, process for producing them and pharmaceutical compositions containing the same
NO20054787L (no) Indenderivater som farmasotiske midler
EP1566446A4 (en) BETA-1,4-MANNOBIOSE-CONTAINING COMPOSITION
GEP20074075B (en) Indazolamides with analgesic activity
NO20034029D0 (no) Substituerte dimetyl-[1-(1-fenyl-cykloheksyl)-piperidin-3-yl metyl]-aminerog anvendelse derav som analgetika
DE50107490D1 (de) Stoffgemisch enthaltend bisphenol a
EA200501818A1 (ru) Индазолы, обладающие анальгетической активностью

Legal Events

Date Code Title Description
FC2A Withdrawal, rejection or dismissal of laid open patent application