NO20034148L - Triazaspiro[5.5]undekanderivater og legemidler inneholdende disse som den aktive bestanddel - Google Patents

Triazaspiro[5.5]undekanderivater og legemidler inneholdende disse som den aktive bestanddel

Info

Publication number: NO20034148L
Authority: NO; Norway
Prior art keywords: formula; triazaspiro; alkyl; active ingredient; drugs containing
Prior art date: 2001-03-19

Application number

NO20034148A

Other languages

English (en)

Norwegian (no)

Other versions

NO20034148D0 (no

Inventor

Hiromu Habashita

Shin-Ichi Hamano

Shiro Shibayama

Yoshikazu Takaoka

Original Assignee

Ono Pharmaceutical Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2001-03-19

Filing date

2003-09-17

Publication date

2003-11-14

2003-09-17 Application filed by Ono Pharmaceutical Co filed Critical Ono Pharmaceutical Co

2003-09-17 Publication of NO20034148D0 publication Critical patent/NO20034148D0/no

2003-11-14 Publication of NO20034148L publication Critical patent/NO20034148L/no

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/10—Spiro-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/02—Nasal agents, e.g. decongestants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/04—Antipruritics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/06—Antigout agents, e.g. antihyperuricemic or uricosuric agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/14—Decongestants or antiallergics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Immunology (AREA)
Pulmonology (AREA)
Oncology (AREA)
Diabetes (AREA)
Dermatology (AREA)
Communicable Diseases (AREA)
Rheumatology (AREA)
Pain & Pain Management (AREA)
Physical Education & Sports Medicine (AREA)
Virology (AREA)
Hematology (AREA)
Urology & Nephrology (AREA)
Ophthalmology & Optometry (AREA)
Emergency Medicine (AREA)
Gastroenterology & Hepatology (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
Transplantation (AREA)
Endocrinology (AREA)
Obesity (AREA)
AIDS & HIV (AREA)
Tropical Medicine & Parasitology (AREA)
Molecular Biology (AREA)
Heart & Thoracic Surgery (AREA)
Neurosurgery (AREA)

NO20034148A 2001-03-19 2003-09-17 Triazaspiro[5.5]undekanderivater og legemidler inneholdende disse som den aktive bestanddel NO20034148L (no)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
JP2001079610		2001-03-19
JP2001160251		2001-05-29
PCT/JP2002/002554 WO2002074770A1 (en)	2001-03-19	2002-03-18	Triazaspiro[5.5]undecane derivatives and drugs containing the same as the active ingredient

Publications (2)

Publication Number	Publication Date
NO20034148D0 NO20034148D0 (no)	2003-09-17
NO20034148L true NO20034148L (no)	2003-11-14

Family

ID=26611613

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO20034148A NO20034148L (no)	2001-03-19	2003-09-17	Triazaspiro[5.5]undekanderivater og legemidler inneholdende disse som den aktive bestanddel

Country Status (23)

Country	Link
US (2)	US7053090B2 (cs)
EP (2)	EP1378510B1 (cs)
JP (1)	JP3558079B2 (cs)
KR (1)	KR100714154B1 (cs)
CN (1)	CN1291988C (cs)
AT (1)	ATE328884T1 (cs)
AU (1)	AU2002238947B2 (cs)
BR (1)	BR0208167A (cs)
CA (1)	CA2440264A1 (cs)
CZ (1)	CZ20032531A3 (cs)
DE (1)	DE60212110T2 (cs)
DK (1)	DK1378510T3 (cs)
ES (1)	ES2266452T3 (cs)
HU (1)	HUP0400229A2 (cs)
IL (1)	IL157819A0 (cs)
MX (1)	MXPA03008529A (cs)
NO (1)	NO20034148L (cs)
NZ (1)	NZ528249A (cs)
PL (1)	PL364427A1 (cs)
PT (1)	PT1378510E (cs)
RU (1)	RU2269528C2 (cs)
TW (1)	TWI254047B (cs)
WO (1)	WO2002074770A1 (cs)

Families Citing this family (36)

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EP1378509A4 (en) *	2001-03-19	2009-03-25	Ono Pharmaceutical Co	DRUGS WITH TRIAZASPIRO ç5.5] UNDECANDERIVATES AS ACTIVE SUBSTANCE
US7361758B2 (en)	2002-09-18	2008-04-22	Ono Pharmaceutical Co., Ltd.	Crystals of triazaspiro[5.5]undecane derivative
CA2497903A1 (en) *	2002-09-18	2004-04-01	Ono Pharmaceutical Co., Ltd.	Triazaspiro[5.5]undecane derivatives and drugs comprising the same as the active ingredient
WO2004054581A2 (en) *	2002-12-13	2004-07-01	Smithkline Beecham Corporation	Cyclohexyl compounds as ccr5 antagonists
EP1570860A4 (en) *	2002-12-13	2009-06-03	Ono Pharmaceutical Co	ANTAGONIST AND AGONIST BINDING TO A STRONG BINDING SITE OF THE CHEMOKINE RECEPTOR
WO2004055016A1 (en) *	2002-12-13	2004-07-01	Smithkline Beecham Corporation	Pyrrolidine and azetidine compounds as ccr5 antagonists
RU2366655C2 (ru)	2003-03-14	2009-09-10	Оно Фармасьютикал Ко., Лтд.	Азотсодержащие гетероциклические производные и лекарственные средства, содержащие их в качестве активного ингредиента
WO2004092169A1 (ja) *	2003-04-18	2004-10-28	Ono Pharmaceutical Co., Ltd.	スピロピペリジン化合物およびその医薬用途
EP1621540A4 (en) *	2003-04-21	2008-07-23	Ono Pharmaceutical Co	HETEROCYCLIC COMPOUNDS CONTAINING NITROGEN AND USE THEREOF
WO2004098638A1 (ja) *	2003-05-06	2004-11-18	Ono Pharmaceutical Co., Ltd.	エフェクター細胞機能阻害剤
EP1790639B1 (en)	2004-08-27	2014-03-26	Ono Pharmaceutical Co., Ltd.	Spirocyclic compounds and their use as cxcr4-antagonists
US8143404B2 (en)	2004-09-13	2012-03-27	Ono Pharmaceutical Co., Ltd	Nitrogenous heterocylic derivative and medicine containing the same as an active ingredient
WO2006090853A1 (ja)	2005-02-25	2006-08-31	Ono Pharmaceutical Co., Ltd.	含窒素複素環化合物およびその医薬用途
CN101163690A (zh)	2005-04-20	2008-04-16	默克公司	苯并噻吩异羟肟酸衍生物
CA2605110A1 (en)	2005-04-20	2006-11-02	Merck & Co., Inc.	Benzothiophene derivatives
EP1874294A4 (en)	2005-04-20	2010-12-01	Merck Sharp & Dohme	BENZOTHIOPHENO HYDROXAMIDIC DERIVATIVES WITH CARBAMATE, UREA, AMID AND SULPHONAMIDE SUBSTITUTIONS
EP1889622A4 (en) *	2005-05-31	2009-12-23	Ono Pharmaceutical Co	SPIROPIPERIDINE COMPOUND AND MEDICINAL USE THEREOF
CA2612420A1 (en)	2005-06-24	2007-01-04	Merck & Co., Inc.	Modified malonate derivatives
WO2007058322A1 (ja)	2005-11-18	2007-05-24	Ono Pharmaceutical Co., Ltd.	塩基性基を含有する化合物およびその用途
AR057579A1 (es)	2005-11-23	2007-12-05	Merck & Co Inc	Compuestos espirociclicos como inhibidores de histona de acetilasa (hdac)
WO2007100657A2 (en)	2006-02-28	2007-09-07	Merck & Co., Inc.	Inhibitors of histone deacetylase
CA2644368A1 (en) *	2006-03-10	2007-09-20	Ono Pharmaceutical Co., Ltd.	Nitrogenated heterocyclic derivative, and pharmaceutical agent comprising the derivative as active ingredient
CA2649861A1 (en)	2006-04-26	2007-11-08	Merck & Co., Inc.	Disubstituted aniline compounds
WO2007132846A1 (ja)	2006-05-16	2007-11-22	Ono Pharmaceutical Co., Ltd.	保護されていてもよい酸性基を含有する化合物およびその用途
EP2023924B1 (en)	2006-05-18	2016-08-03	Merck Sharp & Dohme Corp.	Aryl-fused spirocyclic compounds
EP2049124A4 (en)	2006-07-20	2010-02-10	Merck & Co Inc	PHOSPHOR DERIVATIVES AS HISTONDEACETYLASE HEMMER
RU2320660C1 (ru) *	2007-01-31	2008-03-27	Государственное образовательное учреждение высшего профессионального образования "Пермский государственный университет"	1-АРОИЛОКСИ-4-ГИДРОКСИ-3-ОКСО-1,2,3,4,4а,5,6,7,8,8а-ДЕКАГИДРОХИНОКСАЛИН-2-СПИРО(1-о-ГИДРОКСИФЕНИЛ-4,5-ДИОКСО-2,3,4,5-ТЕТРАГИДРОПИРРОЛЫ) И СПОСОБ ИХ ПОЛУЧЕНИЯ
EP2170339B1 (en)	2007-06-27	2014-10-15	Merck Sharp & Dohme Corp.	Pyridyl and pyrimidinyl derivatives as histone deacetylase inhibitors
AU2008269154B2 (en)	2007-06-27	2014-06-12	Merck Sharp & Dohme Llc	4-carboxybenzylamino derivatives as histone deacetylase inhibitors
WO2010009196A1 (en) *	2008-07-15	2010-01-21	Temple University Of The Commonwealth System Of Higher Education	Synthesis of bis-peptides oligomers comprising at least one n-substituted diketopiperazine as structural moiety
RU2387651C1 (ru) *	2008-12-18	2010-04-27	Государственное образовательное учреждение высшего профессионального образования "Пермский государственный университет"	Этил 1'-бензил-3,3-диметил-1,2'-диоксо-5'-фенил-1',2,2',3,4,10-гексагидро-1н-спиро[акридин-9,3'-пиррол]-4'-карбоксилаты и способ их получения
RU2455284C1 (ru) *	2011-03-15	2012-07-10	Государственное образовательное учреждение высшего профессионального образования "Пермский государственный университет"	Способ получения 5-арил-2-метил-1,3-диоксо-2-азаспиро[5,5]ундекан-4-карбонитрилов и средство, проявляющее анальгетическую активность
KR102030127B1 (ko) *	2019-01-10	2019-10-08	주식회사 보타닉센스	운데칸 또는 운데칸알을 유효성분으로 포함하는 항알러지, 아토피 피부염 개선, 또는 피부 재생용 조성물
TW202110844A (zh) *	2019-06-04	2021-03-16	日商第一三共股份有限公司	具有二螺二酮哌構造之化合物
RU2752079C1 (ru) *	2020-12-01	2021-07-22	Федеральное государственное автономное образовательное учреждение высшего образования "Пермский государственный национальный исследовательский университет"	(Е)-(6-(2-гидроксифенил)-2-иминио-4,7,8-триоксо-1,3-дифенил-1,3,6-триазаспиро[4.4]нонан-9-илиден)(4-метоксифенил)метаноат, обладающий противомикробной активностью, и способ его получения
CN119139317B (zh) *	2024-11-19	2025-03-28	中国科学院杭州医学研究所	化合物在制备治疗过敏性鼻炎的药物中的应用

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WO1997011940A1 (en) *	1995-09-29	1997-04-03	Eli Lilly And Company	Spiro compounds as inhibitors of fibrinogen-dependent platelet aggregation
WO1998025605A1 (en) *	1996-12-13	1998-06-18	Merck & Co., Inc.	Spiro-substituted azacycles as modulators of chemokine receptor activity
CA2278309A1 (en) *	1997-01-21	1998-07-23	Merck & Co., Inc.	3,3-disubstituted piperidines as modulators of chemokine receptor activity
US6288083B1 (en) *	1998-09-04	2001-09-11	Millennium Pharmaceuticals, Inc.	Chemokine receptor antagonists and methods of use therefor
EP1236726B1 (en)	1999-12-03	2004-12-01	Ono Pharmaceutical Co., Ltd.	Triazaspiro 5.5]undecane derivatives and drugs containing the same as the active ingredient
RU2265021C2 (ru) *	1999-12-03	2005-11-27	Оно Фармасьютикал Ко., Лтд.	Производные триазаспиро[5,5]ундекана (варианты), фармацевтическая композиция и способ регулирования хемокина/рецептора хемокина
EP1378509A4 (en)	2001-03-19	2009-03-25	Ono Pharmaceutical Co	DRUGS WITH TRIAZASPIRO ç5.5] UNDECANDERIVATES AS ACTIVE SUBSTANCE

2002
- 2002-03-18 CZ CZ20032531A patent/CZ20032531A3/cs unknown
- 2002-03-18 DE DE60212110T patent/DE60212110T2/de not_active Expired - Fee Related
- 2002-03-18 AU AU2002238947A patent/AU2002238947B2/en not_active Ceased
- 2002-03-18 CN CNB028100824A patent/CN1291988C/zh not_active Expired - Fee Related
- 2002-03-18 NZ NZ528249A patent/NZ528249A/en unknown
- 2002-03-18 MX MXPA03008529A patent/MXPA03008529A/es active IP Right Grant
- 2002-03-18 IL IL15781902A patent/IL157819A0/xx unknown
- 2002-03-18 KR KR1020037012168A patent/KR100714154B1/ko not_active Expired - Fee Related
- 2002-03-18 ES ES02705301T patent/ES2266452T3/es not_active Expired - Lifetime
- 2002-03-18 HU HU0400229A patent/HUP0400229A2/hu unknown
- 2002-03-18 DK DK02705301T patent/DK1378510T3/da active
- 2002-03-18 PT PT02705301T patent/PT1378510E/pt unknown
- 2002-03-18 BR BR0208167-9A patent/BR0208167A/pt not_active IP Right Cessation
- 2002-03-18 RU RU2003128067/04A patent/RU2269528C2/ru not_active IP Right Cessation
- 2002-03-18 WO PCT/JP2002/002554 patent/WO2002074770A1/ja not_active Ceased
- 2002-03-18 JP JP2002573779A patent/JP3558079B2/ja not_active Expired - Fee Related
- 2002-03-18 AT AT02705301T patent/ATE328884T1/de not_active IP Right Cessation
- 2002-03-18 PL PL02364427A patent/PL364427A1/xx not_active Application Discontinuation
- 2002-03-18 CA CA002440264A patent/CA2440264A1/en not_active Abandoned
- 2002-03-18 EP EP02705301A patent/EP1378510B1/en not_active Expired - Lifetime
- 2002-03-18 US US10/472,555 patent/US7053090B2/en not_active Expired - Fee Related
- 2002-03-18 EP EP05105154A patent/EP1619194A3/en not_active Withdrawn
- 2002-03-19 TW TW091105129A patent/TWI254047B/zh not_active IP Right Cessation
2003
- 2003-09-17 NO NO20034148A patent/NO20034148L/no unknown
2005
- 2005-05-24 US US11/135,272 patent/US7262193B2/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
EP1378510A1 (en)	2004-01-07
RU2003128067A (ru)	2005-04-10
MXPA03008529A (es)	2004-06-30
EP1378510B1 (en)	2006-06-07
EP1619194A2 (en)	2006-01-25
US7262193B2 (en)	2007-08-28
CZ20032531A3 (cs)	2004-01-14
US20040082584A1 (en)	2004-04-29
JP3558079B2 (ja)	2004-08-25
KR20040008142A (ko)	2004-01-28
ES2266452T3 (es)	2007-03-01
EP1378510A4 (en)	2004-09-29
CN1291988C (zh)	2006-12-27
HUP0400229A2 (hu)	2004-08-30
DK1378510T3 (da)	2006-10-16
NO20034148D0 (no)	2003-09-17
ATE328884T1 (de)	2006-06-15
US7053090B2 (en)	2006-05-30
BR0208167A (pt)	2004-03-09
EP1619194A3 (en)	2006-06-07
DE60212110D1 (de)	2006-07-20
TWI254047B (en)	2006-05-01
CA2440264A1 (en)	2002-09-26
AU2002238947B2 (en)	2007-10-18
JPWO2002074770A1 (ja)	2004-07-08
IL157819A0 (en)	2004-03-28
KR100714154B1 (ko)	2007-05-07
US20050215557A1 (en)	2005-09-29
PT1378510E (pt)	2006-09-29
CN1518551A (zh)	2004-08-04
NZ528249A (en)	2005-03-24
RU2269528C2 (ru)	2006-02-10
WO2002074770A1 (en)	2002-09-26
PL364427A1 (en)	2004-12-13
DE60212110T2 (de)	2006-11-09

Publication	Publication Date	Title
NO20034148L (no)	2003-11-14	Triazaspiro[5.5]undekanderivater og legemidler inneholdende disse som den aktive bestanddel
NO20022609D0 (no)	2002-05-31	Triazaspiro[5,5]undekan-derivater og medikamenter inneholdende slike som den aktive bestanddel
MX9206258A (es)	1993-04-01	Derivados de 1,3-dihidro-2h-imidazo(4,5-b)quinolin-2-ona.
HRP20040317A2 (en)	2006-06-30	1,8-naphthyridine derivatives as antidiabetics
PT1608374E (pt)	2008-12-24	Derivados de 2-fenoxi- e 2-fenilsulfonamida com actividade antagonista do ccr3 para o tratamento da asma e de outras desordens inflamatórias e imunológicas
WO2005018557A3 (en)	2005-08-04	Substituted pyridinones
NO20050164L (no)	2005-04-04	Nye quinuklidin-amid-derivater
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NO20052493L (no)	2005-05-24	Selekterte CGRP antagonister, fremgangsmater for fremstilling derav og deres anvendelse som farmasoytiske sammensetninger.
ATE221064T1 (de)	2002-08-15	Cyclische amidderivate als neurokinin a antagonisten
DE60322359D1 (de)	2008-09-04	Imidazopyridinderivate als kinaseinhibitoren
NO20045486L (no)	2005-02-02	Nye forbindelser og deres anvendelse
NO20040589L (no)	2004-03-19	Arylsulfonylderivater med 5-HT6 reseptor affinitet.
AU8811401A (en)	2002-04-02	Spiro compounds and adhesion molecule inhibitors containing the same as the active ingredient
TH77892A (th)	2006-06-05	อนุพันธ์เบนซ์ออกซาซีพีน