NO20041681L - Substituerte 4-fenyl-4-[1H-imidazol-2-yl]-piperidinderivater for reduksjon av iskemisk skade - Google Patents

Substituerte 4-fenyl-4-[1H-imidazol-2-yl]-piperidinderivater for reduksjon av iskemisk skade

Info

Publication number: NO20041681L
Authority: NO; Norway
Prior art keywords: imidazol; phenyl; substituted; ischemic damage; agent
Prior art date: 2001-10-15

Application number

NO20041681A

Other languages

English (en)

Norwegian (no)

Inventor

Marcel Jan Maria Borgers

Frans Eduard Janssens

Joseph Elisabeth Leenaerts

Francisco Javi Fernandez-Gadea

Theo Frans Meerts

Antonio Gomez-Sanchez

Willem Flameng

Paul Joannes Ludovic Herijgers

Original Assignee

Janssen Pharmaceutica Nv

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2001-10-15

Filing date

2004-04-23

Publication date

2004-04-23

2004-04-23 Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv

2004-04-23 Publication of NO20041681L publication Critical patent/NO20041681L/no

Links

230000000302 ischemic effect Effects 0.000 title abstract 3
GBANLFWFVPIRMO-UHFFFAOYSA-N 4-(1h-imidazol-2-yl)-4-phenylpiperidine Chemical class C1CNCCC1(C=1C=CC=CC=1)C1=NC=CN1 GBANLFWFVPIRMO-UHFFFAOYSA-N 0.000 title abstract 2
210000004556 brain Anatomy 0.000 abstract 3
241000124008 Mammalia Species 0.000 abstract 2
210000000056 organ Anatomy 0.000 abstract 2
230000002265 prevention Effects 0.000 abstract 2
230000003293 cardioprotective effect Effects 0.000 abstract 1
208000029078 coronary artery disease Diseases 0.000 abstract 1
230000001939 inductive effect Effects 0.000 abstract 1
208000023589 ischemic disease Diseases 0.000 abstract 1
239000008194 pharmaceutical composition Substances 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/454—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Chemical & Material Sciences (AREA)
General Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Medicinal Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
Epidemiology (AREA)
Heart & Thoracic Surgery (AREA)
Cardiology (AREA)
Urology & Nephrology (AREA)
Vascular Medicine (AREA)
Pulmonology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)

NO20041681A 2001-10-15 2004-04-23 Substituerte 4-fenyl-4-[1H-imidazol-2-yl]-piperidinderivater for reduksjon av iskemisk skade NO20041681L (no)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
EP01203927		2001-10-15
PCT/EP2002/011371 WO2003039440A2 (en)	2001-10-15	2002-10-10	Substituted 4-phenyl-4-(1h-imidazol-2-yl)-piperidine derivatives for reducing ischaemic damage

Publications (1)

Publication Number	Publication Date
NO20041681L true NO20041681L (no)	2004-04-23

Family

ID=8181081

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO20041681A NO20041681L (no)	2001-10-15	2004-04-23	Substituerte 4-fenyl-4-[1H-imidazol-2-yl]-piperidinderivater for reduksjon av iskemisk skade

Country Status (26)

Country	Link
US (1)	US7390822B2 (de)
EP (1)	EP1438049B1 (de)
JP (1)	JP4418676B2 (de)
KR (1)	KR100967599B1 (de)
CN (1)	CN1283252C (de)
AR (1)	AR036800A1 (de)
AT (1)	ATE345799T1 (de)
AU (1)	AU2002363369B2 (de)
BR (1)	BR0213325A (de)
CA (1)	CA2462374C (de)
CY (1)	CY1106335T1 (de)
DE (1)	DE60216310T2 (de)
EA (1)	EA007657B1 (de)
ES (1)	ES2276980T3 (de)
HR (1)	HRP20040325A2 (de)
HU (1)	HUP0402332A3 (de)
IL (1)	IL161347A0 (de)
MX (1)	MXPA04003480A (de)
MY (1)	MY139586A (de)
NO (1)	NO20041681L (de)
NZ (1)	NZ531733A (de)
PL (1)	PL370371A1 (de)
PT (1)	PT1438049E (de)
UA (1)	UA75980C2 (de)
WO (1)	WO2003039440A2 (de)
ZA (1)	ZA200402816B (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
TW200403058A (en) *	2002-04-19	2004-03-01	Bristol Myers Squibb Co	Heterocyclo inhibitors of potassium channel function
AR044010A1 (es) *	2003-04-11	2005-08-24	Janssen Pharmaceutica Nv	Uso de derivados de 4-fenil-4- [1h-imidazol-2-il]- piperidina sustituidos como agonistas delta opioideos no peptidos selectivos, con actividad antidepresiva y ansiolitica
WO2005005478A2 (en) *	2003-07-02	2005-01-20	Bayer Healthcare Ag	Diagnostics and therapeutics for diseases associated with g protein-coupled opioid receptor; delta 1 (oprd1)
WO2005015242A1 (en) *	2003-08-06	2005-02-17	Bayer Healthcare Ag	Diagnostics and therapeutics for diseases associated with g protein-coupled opioid receptor kappa 1 (opkr1)
TW200633990A (en) *	2004-11-18	2006-10-01	Takeda Pharmaceuticals Co	Amide compound
KR20100114018A (ko) *	2007-11-30	2010-10-22	바이엘 쉐링 파마 악티엔게젤샤프트	헤테로아릴-치환된 피페리딘
DE102009014484A1 (de)	2009-03-23	2010-09-30	Bayer Schering Pharma Aktiengesellschaft	Substituierte Piperidine
DE102009022896A1 (de)	2009-05-27	2010-12-02	Bayer Schering Pharma Aktiengesellschaft	Substituierte Piperidine
DE102009022894A1 (de)	2009-05-27	2010-12-02	Bayer Schering Pharma Aktiengesellschaft	Substituierte Piperidine
DE102009056387B9 (de) *	2009-10-30	2020-05-07	Osram Opto Semiconductors Gmbh	Kantenemittierender Halbleiterlaser mit einem Phasenstrukturbereich zur Selektion lateraler Lasermoden
JP7450534B2 (ja)	2017-10-19	2024-03-15	帝人ファーマ株式会社	ベンズイミダゾール誘導体及びその用途
CN113209294B (zh) *	2020-02-05	2023-06-13	复旦大学	Dor激动剂在制备对抗肾脏纤维化药物中的应用

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CN1488353A (zh)	1995-03-06	2004-04-14	Ӣ��Ŧ¡��ҩ��޹�˾	用于治疗发生缺血患者的组合物
AU729880C (en)	1996-08-23	2001-11-08	Vegenics Limited	Recombinant vascular endothelial cell growth factor D (VEGF-D)
NZ500530A (en)	1997-04-25	2001-12-21	Collateral Therapeutics	Truncated VEGF-B, VEGF-C, VEGF-3, PlGF, VRF-2, poxvirus ORF-1 and ORF-2 proteins
US6103722A (en) *	1997-07-23	2000-08-15	The Medical College Of Wisconsin Research Foundation Inc.	Ischemic preconditioning
GB2332373A (en)	1997-12-19	1999-06-23	Merck & Co Inc	Treatment of coronary and/or peripheral ischemia using an antithrombotic agent and an angiogenesis promoter
SI1144411T1 (en)	1998-12-19	2005-10-31	Janssen Pharmaceutica N.V.	Antihistaminic spiro compounds
EP1038872A1 (de) *	1999-02-22	2000-09-27	Pfizer Products Inc.	4-Phenyl-4-heteroarylpiperdine Derivate als Opioid-Rezeptorligande
US6297256B1 (en) *	1999-06-15	2001-10-02	Neurogen Corporation	Aryl and heteroaryl substituted pyridino derivatives GABA brain receptor ligands
IL161348A0 (en) *	2001-10-15	2004-09-27	Janssen Pharmaceutica Nv	Novel substituted 4-phenyl-4-[1h-imidazol-2-yl]piperidine derivatives and their use as selective non-peptide delta opioid agonists
FR2831166B1 (fr)	2001-10-18	2004-02-27	Sanofi Synthelabo	Aralkyl-tetrahydro-pyridines, leur preparation et compositions pharmaceutiques les contenant

2002
- 2002-10-10 BR BR0213325-3A patent/BR0213325A/pt not_active Application Discontinuation
- 2002-10-10 DE DE60216310T patent/DE60216310T2/de not_active Expired - Lifetime
- 2002-10-10 HR HR20040325A patent/HRP20040325A2/hr not_active Application Discontinuation
- 2002-10-10 IL IL16134702A patent/IL161347A0/xx not_active IP Right Cessation
- 2002-10-10 CA CA2462374A patent/CA2462374C/en not_active Expired - Lifetime
- 2002-10-10 AU AU2002363369A patent/AU2002363369B2/en not_active Ceased
- 2002-10-10 JP JP2003541732A patent/JP4418676B2/ja not_active Expired - Fee Related
- 2002-10-10 US US10/492,778 patent/US7390822B2/en not_active Expired - Fee Related
- 2002-10-10 MX MXPA04003480A patent/MXPA04003480A/es active IP Right Grant
- 2002-10-10 HU HU0402332A patent/HUP0402332A3/hu unknown
- 2002-10-10 AT AT02799040T patent/ATE345799T1/de active
- 2002-10-10 KR KR1020047002380A patent/KR100967599B1/ko not_active Expired - Fee Related
- 2002-10-10 EP EP02799040A patent/EP1438049B1/de not_active Expired - Lifetime
- 2002-10-10 NZ NZ531733A patent/NZ531733A/en not_active IP Right Cessation
- 2002-10-10 PT PT02799040T patent/PT1438049E/pt unknown
- 2002-10-10 CN CNB028202961A patent/CN1283252C/zh not_active Expired - Fee Related
- 2002-10-10 WO PCT/EP2002/011371 patent/WO2003039440A2/en not_active Ceased
- 2002-10-10 EA EA200400547A patent/EA007657B1/ru not_active IP Right Cessation
- 2002-10-10 ES ES02799040T patent/ES2276980T3/es not_active Expired - Lifetime
- 2002-10-10 PL PL02370371A patent/PL370371A1/xx not_active Application Discontinuation
- 2002-10-10 UA UA20040503666A patent/UA75980C2/uk unknown
- 2002-10-11 AR ARP020103836A patent/AR036800A1/es unknown
- 2002-10-11 MY MYPI20023801A patent/MY139586A/en unknown
2004
- 2004-04-13 ZA ZA2004/02816A patent/ZA200402816B/en unknown
- 2004-04-23 NO NO20041681A patent/NO20041681L/no not_active Application Discontinuation
2007
- 2007-02-22 CY CY20071100249T patent/CY1106335T1/el unknown

Also Published As

Publication number	Publication date
WO2003039440A3 (en)	2003-12-18
KR100967599B1 (ko)	2010-07-05
HUP0402332A3 (en)	2009-07-28
HUP0402332A2 (hu)	2005-02-28
HRP20040325A2 (en)	2005-04-30
DE60216310D1 (de)	2007-01-04
EP1438049B1 (de)	2006-11-22
AU2002363369B2 (en)	2008-08-21
ZA200402816B (en)	2005-06-29
AR036800A1 (es)	2004-10-06
JP4418676B2 (ja)	2010-02-17
NZ531733A (en)	2006-04-28
JP2005507943A (ja)	2005-03-24
CN1568186A (zh)	2005-01-19
CN1283252C (zh)	2006-11-08
MXPA04003480A (es)	2004-07-30
PT1438049E (pt)	2007-02-28
UA75980C2 (en)	2006-06-15
KR20050035120A (ko)	2005-04-15
HK1072562A1 (en)	2005-09-02
DE60216310T2 (de)	2007-06-21
CY1106335T1 (el)	2011-10-12
US7390822B2 (en)	2008-06-24
MY139586A (en)	2009-10-30
BR0213325A (pt)	2004-10-13
WO2003039440A2 (en)	2003-05-15
EP1438049A2 (de)	2004-07-21
ES2276980T3 (es)	2007-07-01
US20050004170A1 (en)	2005-01-06
CA2462374C (en)	2011-01-18
ATE345799T1 (de)	2006-12-15
PL370371A1 (en)	2005-05-16
IL161347A0 (en)	2004-09-27
EA200400547A1 (ru)	2004-10-28
EA007657B1 (ru)	2006-12-29
CA2462374A1 (en)	2003-05-15

Legal Events

Date	Code	Title	Description
2013-05-27	FC2A	Withdrawal, rejection or dismissal of laid open patent application

Publication	Publication Date	Title
NO20041681L (no)	2004-04-23	Substituerte 4-fenyl-4-[1H-imidazol-2-yl]-piperidinderivater for reduksjon av iskemisk skade
EP1562897A4 (de)	2007-06-27	Phenylcarboxamide als beta-sekretase-hemmer zur behandlung von alzheimer
NO20045137L (no)	2004-11-25	Diketohydrazinderivatforbindelser og legemidler inneholdende forbindelser som aktiv ingrediens
WO2001015593A3 (en)	2001-09-13	Compositions for reducing vascular plaque formation and methods of using same
EP2266569A3 (de)	2011-03-09	Heterozyklische Derivate und ihre Verwendung als Stearoyl-Coa-Desaturase-Inhibitoren
TNSN04246A1 (fr)	2007-03-12	Derives d'heteroarylamides benzocondenses de thienopyridines utiles comme agents therapeutiques, compositions pharmaceutiques les contenant et methodes pour leur utilisation
IL173032A0 (en)	2006-06-11	Pyridazine derivatives and their use as therapeutic agents
TW200736252A (en)	2007-10-01	Novel heteroaryl substituted benzothiazoles
EP1014996A4 (de)	2000-10-11	Zubereitung enthaltende saccharide und methoden zur behandlung von alzheimerschen erkrankung und von weiteren amyloidosen
BRPI0515483A (pt)	2008-07-22	derivados heterocìclicos para o tratamento de doenças mediadas por enzimas estearoil-coa desaturase
ATE375341T1 (de)	2007-10-15	Thiadiazolylpiperazinderivate geeignet für die behandlung bzw. prävention von schmerzen
NO20053644L (no)	2002-10-22	(2S)-2-[(4S)-4-(2,2-difluorvinyl)-2-oksopyrrolidinyl ]butanamid og farmasoytisk preparat
MXPA05008172A (es)	2005-10-05	Derivados de malonamida como inhibidores gamma-secretasa.
MXPA04000328A (es)	2004-07-23	Derivados de alfa-hidroxiamida estatina para tratamiento de enfermedad de alzheimer.
ATE541854T1 (de)	2012-02-15	Pyrazolderivat, arzneimittelzusammensetzung, die dieses enthält, und zwischenprodukt für dessen herstellung
EP0444196A4 (en)	1991-11-27	Agent for treatment and prophylaxis of ischemic disease of heart or brain
DE60135108D1 (de)	2008-09-11	Dermale zusammenstellungen die als wirkstoff coenzym q enthalten
DK1392329T3 (da)	2006-11-27	Anvendelse af sulodexid til behandling af inflammatorisk tarmsygdom
AR034343A1 (es)	2004-02-18	Combinaciones farmaceuticas
DE602004007268D1 (de)	2007-08-09	CYCLOALKYLSULFANYL-SUBSTITUIERTE BENZOiBöTHIOPHENE ALS THERAPEUTISCHE MITTEL
MY147347A (en)	2012-11-30	Novel 2-heteroaryl substituted benzothiophenes and benzofuranes
ATE366107T1 (de)	2007-07-15	Verwendung von sulfodehydroabietinsäure zur behandlung entzündlicher darmerkrankungen
CY1110644T1 (el)	2015-04-29	5,6,7-τριυδροξυεπτανοϊκο οξυ και τα αναλογα για την θεραπεια οφθαλμικων ασθενειων που σχετιζονται με υπερεκφυτικες και αγγειογενεις αντιδρασεις
NO20050573L (no)	2005-02-02	4-'7-halo-2-quino (XA) linyloksy ! fenoksypropionsyrederivater som antineoplastiske midler
DE60137442D1 (de)	2009-03-05	5-amidino-2-hydroxybenzolsulfonamidderivate, pharmazeutischen zusammensetzungen, die diese verbindungen enthalten, und zwischenprodukte zu deren herstellung