NO20041681L - Substituerte 4-fenyl-4-[1H-imidazol-2-yl]-piperidinderivater for reduksjon av iskemisk skade - Google Patents
Substituerte 4-fenyl-4-[1H-imidazol-2-yl]-piperidinderivater for reduksjon av iskemisk skadeInfo
- Publication number
- NO20041681L NO20041681L NO20041681A NO20041681A NO20041681L NO 20041681 L NO20041681 L NO 20041681L NO 20041681 A NO20041681 A NO 20041681A NO 20041681 A NO20041681 A NO 20041681A NO 20041681 L NO20041681 L NO 20041681L
- Authority
- NO
- Norway
- Prior art keywords
- imidazol
- phenyl
- substituted
- ischemic damage
- agent
- Prior art date
Links
- 230000000302 ischemic effect Effects 0.000 title abstract 3
- GBANLFWFVPIRMO-UHFFFAOYSA-N 4-(1h-imidazol-2-yl)-4-phenylpiperidine Chemical class C1CNCCC1(C=1C=CC=CC=1)C1=NC=CN1 GBANLFWFVPIRMO-UHFFFAOYSA-N 0.000 title abstract 2
- 210000004556 brain Anatomy 0.000 abstract 3
- 241000124008 Mammalia Species 0.000 abstract 2
- 210000000056 organ Anatomy 0.000 abstract 2
- 230000002265 prevention Effects 0.000 abstract 2
- 230000003293 cardioprotective effect Effects 0.000 abstract 1
- 208000029078 coronary artery disease Diseases 0.000 abstract 1
- 230000001939 inductive effect Effects 0.000 abstract 1
- 208000023589 ischemic disease Diseases 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/454—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Pulmonology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP01203927 | 2001-10-15 | ||
| PCT/EP2002/011371 WO2003039440A2 (en) | 2001-10-15 | 2002-10-10 | Substituted 4-phenyl-4-(1h-imidazol-2-yl)-piperidine derivatives for reducing ischaemic damage |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NO20041681L true NO20041681L (no) | 2004-04-23 |
Family
ID=8181081
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20041681A NO20041681L (no) | 2001-10-15 | 2004-04-23 | Substituerte 4-fenyl-4-[1H-imidazol-2-yl]-piperidinderivater for reduksjon av iskemisk skade |
Country Status (26)
| Country | Link |
|---|---|
| US (1) | US7390822B2 (pl) |
| EP (1) | EP1438049B1 (pl) |
| JP (1) | JP4418676B2 (pl) |
| KR (1) | KR100967599B1 (pl) |
| CN (1) | CN1283252C (pl) |
| AR (1) | AR036800A1 (pl) |
| AT (1) | ATE345799T1 (pl) |
| AU (1) | AU2002363369B2 (pl) |
| BR (1) | BR0213325A (pl) |
| CA (1) | CA2462374C (pl) |
| CY (1) | CY1106335T1 (pl) |
| DE (1) | DE60216310T2 (pl) |
| EA (1) | EA007657B1 (pl) |
| ES (1) | ES2276980T3 (pl) |
| HR (1) | HRP20040325A2 (pl) |
| HU (1) | HUP0402332A3 (pl) |
| IL (1) | IL161347A0 (pl) |
| MX (1) | MXPA04003480A (pl) |
| MY (1) | MY139586A (pl) |
| NO (1) | NO20041681L (pl) |
| NZ (1) | NZ531733A (pl) |
| PL (1) | PL370371A1 (pl) |
| PT (1) | PT1438049E (pl) |
| UA (1) | UA75980C2 (pl) |
| WO (1) | WO2003039440A2 (pl) |
| ZA (1) | ZA200402816B (pl) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW200403058A (en) * | 2002-04-19 | 2004-03-01 | Bristol Myers Squibb Co | Heterocyclo inhibitors of potassium channel function |
| CL2004000754A1 (es) * | 2003-04-11 | 2005-02-25 | Janssen Pharmaceutica Nv | Uso de compuestos derivados de 4-fenil-4-(1h-imidazol-2-il)piperidina, como agonistas delta-opioides no peptidicos, para preparar un medicamento util en prevenir o tratar trastornos del sistema nervioso central. |
| WO2005005478A2 (en) * | 2003-07-02 | 2005-01-20 | Bayer Healthcare Ag | Diagnostics and therapeutics for diseases associated with g protein-coupled opioid receptor; delta 1 (oprd1) |
| WO2005015242A1 (en) * | 2003-08-06 | 2005-02-17 | Bayer Healthcare Ag | Diagnostics and therapeutics for diseases associated with g protein-coupled opioid receptor kappa 1 (opkr1) |
| TW200633990A (en) * | 2004-11-18 | 2006-10-01 | Takeda Pharmaceuticals Co | Amide compound |
| JP5450435B2 (ja) * | 2007-11-30 | 2014-03-26 | バイエル・インテレクチュアル・プロパティ・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング | ヘテロアリールで置換されたピペリジン類 |
| DE102009014484A1 (de) | 2009-03-23 | 2010-09-30 | Bayer Schering Pharma Aktiengesellschaft | Substituierte Piperidine |
| DE102009022896A1 (de) | 2009-05-27 | 2010-12-02 | Bayer Schering Pharma Aktiengesellschaft | Substituierte Piperidine |
| DE102009022894A1 (de) | 2009-05-27 | 2010-12-02 | Bayer Schering Pharma Aktiengesellschaft | Substituierte Piperidine |
| DE102009056387B9 (de) * | 2009-10-30 | 2020-05-07 | Osram Opto Semiconductors Gmbh | Kantenemittierender Halbleiterlaser mit einem Phasenstrukturbereich zur Selektion lateraler Lasermoden |
| CN111417394B (zh) | 2017-10-19 | 2023-11-07 | 帝人制药株式会社 | 苯并咪唑衍生物及其用途 |
| CN113209294B (zh) * | 2020-02-05 | 2023-06-13 | 复旦大学 | Dor激动剂在制备对抗肾脏纤维化药物中的应用 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2213000A1 (en) | 1995-03-06 | 1996-09-12 | Interneuron Pharmaceuticals, Inc. | Reduction of infarct volume using citicoline |
| EP0956339B1 (en) | 1996-08-23 | 2005-10-12 | Ludwig Institute For Cancer Research | Recombinant vascular endothelial cell growth factor d (vegf-d) |
| NZ500530A (en) | 1997-04-25 | 2001-12-21 | Collateral Therapeutics | Truncated VEGF-B, VEGF-C, VEGF-3, PlGF, VRF-2, poxvirus ORF-1 and ORF-2 proteins |
| US6103722A (en) | 1997-07-23 | 2000-08-15 | The Medical College Of Wisconsin Research Foundation Inc. | Ischemic preconditioning |
| GB2332373A (en) * | 1997-12-19 | 1999-06-23 | Merck & Co Inc | Treatment of coronary and/or peripheral ischemia using an antithrombotic agent and an angiogenesis promoter |
| BR9916371A (pt) * | 1998-12-19 | 2001-09-18 | Janssen Pharmaceutica Nv | Composto de espiro anti-histamìnico |
| EP1038872A1 (en) * | 1999-02-22 | 2000-09-27 | Pfizer Products Inc. | 4-Phenyl-4-heteroarylpiperdine derivatives as opioid receptor ligands |
| US6297256B1 (en) * | 1999-06-15 | 2001-10-02 | Neurogen Corporation | Aryl and heteroaryl substituted pyridino derivatives GABA brain receptor ligands |
| JP4417108B2 (ja) * | 2001-10-15 | 2010-02-17 | ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ | 新規な置換された４−フェニル−４−［１ｈ−イミダゾール−２−イル］−ピペリジン誘導体および選択的非ペプチドデルタオピオイドアゴニストとしてのそれらの使用 |
| FR2831166B1 (fr) | 2001-10-18 | 2004-02-27 | Sanofi Synthelabo | Aralkyl-tetrahydro-pyridines, leur preparation et compositions pharmaceutiques les contenant |
-
2002
- 2002-10-10 CA CA2462374A patent/CA2462374C/en not_active Expired - Lifetime
- 2002-10-10 NZ NZ531733A patent/NZ531733A/en not_active IP Right Cessation
- 2002-10-10 WO PCT/EP2002/011371 patent/WO2003039440A2/en not_active Ceased
- 2002-10-10 EA EA200400547A patent/EA007657B1/ru not_active IP Right Cessation
- 2002-10-10 MX MXPA04003480A patent/MXPA04003480A/es active IP Right Grant
- 2002-10-10 DE DE60216310T patent/DE60216310T2/de not_active Expired - Lifetime
- 2002-10-10 KR KR1020047002380A patent/KR100967599B1/ko not_active Expired - Fee Related
- 2002-10-10 US US10/492,778 patent/US7390822B2/en not_active Expired - Fee Related
- 2002-10-10 AT AT02799040T patent/ATE345799T1/de active
- 2002-10-10 PT PT02799040T patent/PT1438049E/pt unknown
- 2002-10-10 BR BR0213325-3A patent/BR0213325A/pt not_active Application Discontinuation
- 2002-10-10 JP JP2003541732A patent/JP4418676B2/ja not_active Expired - Fee Related
- 2002-10-10 AU AU2002363369A patent/AU2002363369B2/en not_active Ceased
- 2002-10-10 PL PL02370371A patent/PL370371A1/pl not_active Application Discontinuation
- 2002-10-10 IL IL16134702A patent/IL161347A0/xx not_active IP Right Cessation
- 2002-10-10 HR HR20040325A patent/HRP20040325A2/hr not_active Application Discontinuation
- 2002-10-10 UA UA20040503666A patent/UA75980C2/uk unknown
- 2002-10-10 HU HU0402332A patent/HUP0402332A3/hu unknown
- 2002-10-10 CN CNB028202961A patent/CN1283252C/zh not_active Expired - Fee Related
- 2002-10-10 EP EP02799040A patent/EP1438049B1/en not_active Expired - Lifetime
- 2002-10-10 ES ES02799040T patent/ES2276980T3/es not_active Expired - Lifetime
- 2002-10-11 MY MYPI20023801A patent/MY139586A/en unknown
- 2002-10-11 AR ARP020103836A patent/AR036800A1/es unknown
-
2004
- 2004-04-13 ZA ZA2004/02816A patent/ZA200402816B/en unknown
- 2004-04-23 NO NO20041681A patent/NO20041681L/no not_active Application Discontinuation
-
2007
- 2007-02-22 CY CY20071100249T patent/CY1106335T1/el unknown
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC2A | Withdrawal, rejection or dismissal of laid open patent application |