NO20043595L - Nye kortikosteroider - Google Patents

Nye kortikosteroider

Info

Publication number: NO20043595L
Authority: NO; Norway
Prior art keywords: corticosteroids; new; new corticosteroids
Prior art date: 2002-01-29

Application number

NO20043595A

Other languages

English (en)

Other versions

NO327364B1 (no

Inventor

Piero Del Soldato

Ennio Ongini

Original Assignee

Nicox Sa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2002-01-29

Filing date

2004-08-27

Publication date

2004-10-20

2004-08-27 Application filed by Nicox Sa filed Critical Nicox Sa

2004-10-20 Publication of NO20043595L publication Critical patent/NO20043595L/no

2009-06-15 Publication of NO327364B1 publication Critical patent/NO327364B1/no

Links

239000003246 corticosteroid Substances 0.000 title 1
229960001334 corticosteroids Drugs 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J43/00—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
- C07J43/003—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton not condensed
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
- A61P5/44—Glucocorticosteroids; Drugs increasing or potentiating the activity of glucocorticosteroids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
- C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
- C07J41/005—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 the 17-beta position being substituted by an uninterrupted chain of only two carbon atoms, e.g. pregnane derivatives

Landscapes

Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
General Health & Medical Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Immunology (AREA)
Pulmonology (AREA)
Endocrinology (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Diabetes (AREA)
Rheumatology (AREA)
Ophthalmology & Optometry (AREA)
Cardiology (AREA)
Psychiatry (AREA)
Pain & Pain Management (AREA)
Transplantation (AREA)
Heart & Thoracic Surgery (AREA)
Reproductive Health (AREA)
Hospice & Palliative Care (AREA)
Urology & Nephrology (AREA)
Dermatology (AREA)
Orthopedic Medicine & Surgery (AREA)
Physical Education & Sports Medicine (AREA)
Steroid Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)

NO20043595A 2002-01-29 2004-08-27 Nitrooksyderivater av steroidforbindelser, anvendelse derav, og farmasoytisk formulering omfattende slike NO327364B1 (no)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
IT2002MI000148A ITMI20020148A1 (it)	2002-01-29	2002-01-29	Nuovi corticosteroidi
PCT/EP2003/000394 WO2003064443A2 (en)	2002-01-29	2003-01-16	New corticosteroids

Publications (2)

Publication Number	Publication Date
NO20043595L true NO20043595L (no)	2004-10-20
NO327364B1 NO327364B1 (no)	2009-06-15

Family

ID=11449016

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO20043595A NO327364B1 (no)	2002-01-29	2004-08-27	Nitrooksyderivater av steroidforbindelser, anvendelse derav, og farmasoytisk formulering omfattende slike

Country Status (12)

Country	Link
US (2)	US20060052594A1 (no)
EP (1)	EP1470150A2 (no)
JP (1)	JP2005516070A (no)
AU (2)	AU2003210161B2 (no)
BR (1)	BR0307027A (no)
CA (1)	CA2473249A1 (no)
IT (1)	ITMI20020148A1 (no)
MX (1)	MXPA04007337A (no)
NO (1)	NO327364B1 (no)
NZ (1)	NZ534147A (no)
PL (1)	PL370457A1 (no)
WO (1)	WO2003064443A2 (no)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
RU2006119528A (ru) *	2003-12-02	2008-01-10	Никокс С.А. (Fr)	Нитрооксипроизводные карведилола и других бета-блокаторов в качестве антигипертензивных средств
EP1940863B1 (en) *	2005-09-02	2012-09-05	Nicox S.A.	Nitrooxy derivatives of glucocorticoids
US8802726B2 (en)	2006-02-03	2014-08-12	Nicox S.A.	Use of nitrooxyderivative of drug for the treatment of muscular dystrophies
BRPI0807078A2 (pt) *	2007-02-05	2014-04-08	Nicox Sa	Composto, e, formulação farmacêutica
EP1964550A1 (en) *	2007-03-01	2008-09-03	NicOx S.A.	Glucocorticoid-nitrooxyderivative compositions
US20090087425A1 (en) *	2007-08-10	2009-04-02	Topigen Pharmaceuticals Inc.	Combination of nitroderivatized steroid and bronchodilator for treating respiratory disease
US20090088411A1 (en) *	2007-08-31	2009-04-02	Topigen Pharmaceuticals Inc.	No-donating corticosteroid with improved pharmacokinetic, anti-inflammatory and vasodilatory properties
ES2324007A1 (es) *	2007-10-25	2009-07-28	Ferrer Internacional, S.A.	Una forma amorfa de un compuesto antiinflamatorio.
EP3415151A1 (en) *	2008-05-23	2018-12-19	The University of British Columbia	Modified drugs for use in liposomal nanoparticles
CN101624414B (zh) *	2008-07-07	2013-02-13	天津金耀集团有限公司	一种抑制血管新生的硝酸酯药物
ES2442720T3 (es) *	2008-07-31	2014-02-13	Nicox S.A.	Glucocorticoides unidos a ésteres de nitrato por medio de un enlazador aromático en posición 21 y su uso en oftalmología
CN102186873A (zh)	2008-08-05	2011-09-14	尼科克斯公司	用于治疗视网膜和黄斑疾病的新型释放no的甾类化合物
CN102040643B (zh) *	2009-10-16	2013-01-09	天津金耀集团有限公司	环索奈德硝酸酯衍生物
US8716268B2 (en) *	2010-06-07	2014-05-06	Chao Liu	Nitrate esters of corticoid compounds useful as diuretics
KR20250114431A (ko)	2016-11-08	2025-07-29	리제너론 파마슈티칼스 인코포레이티드	스테로이드 및 이의 단백질-접합체
KR20250008984A (ko)	2017-05-18	2025-01-16	리제너론 파마슈티칼스 인코포레이티드	사이클로덱스트린 단백질 약물 접합체
MX2020004691A (es)	2017-11-07	2020-08-20	Regeneron Pharma	Enlazadores hidrofilicos para conjugados anticuerpo-farmaco.
CN112004557B (zh)	2018-01-08	2024-07-30	里珍纳龙药品有限公司	类固醇类化合物及其抗体偶联物
CN108484714A (zh) *	2018-03-13	2018-09-04	岳阳环宇药业有限公司	地夫可特的制备工艺
CN112533951A (zh)	2018-05-09	2021-03-19	里珍纳龙药品有限公司	抗msr1抗体及其使用方法

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE1037451B (de) *	1957-04-04	1958-08-28	Schering Ag	Verfahren zur Herstellung der Aminoacetate von gesaettigten und ungesaettigten 21-Hydroxypregnan-verbindungen bzw. deren wasserloeslichen Saeureadditionsprodukten
US3183252A (en)	1963-09-05	1965-05-11	Syntex Corp	16-nitratoalkyl-pregnanes
US3494941A (en) *	1967-12-04	1970-02-10	American Home Prod	Nitrate esters of 17beta-(hydroxyalkoxy)steroid 3-ols,3-ones and 3-amidinohydrazones
HU164115B (no)	1971-05-07	1973-12-28
ATE8790T1 (de) *	1981-02-02	1984-08-15	Schering Corporation	Aromatische heterocyclische steroidester, verfahren zu ihrer herstellung und pharmazeutische zusammensetzungen, die sie enthalten.
GR1001529B (el) *	1990-09-07	1994-03-31	Elmuquimica Farm Sl	Μέ?οδος για την λήψη νέων 21-εστέρων της 16-17-ακετάλης της πρ να-1,4-διενο-3,20-διόνης.
US5824669A (en) *	1996-03-22	1998-10-20	Nitromed, Inc.	Nitrosated and nitrosylated compounds and compositions and their use for treating respiratory disorders
US5837698A (en) *	1996-05-02	1998-11-17	G. D. Searle & Co.	Steroid nitrite and nitrate ester derivatives useful as anti-inflammatory drugs
IT1285770B1 (it)	1996-10-04	1998-06-18	Nicox Sa	Composti corticoidei
US6248723B1 (en) *	1997-06-10	2001-06-19	National Jewish Medical And Research Center	Method for treatment of inflammatory disease
US6254853B1 (en) *	1998-05-08	2001-07-03	Vyrex Corporation	Water soluble pro-drugs of propofol
IT1311922B1 (it)	1999-04-13	2002-03-20	Nicox Sa	Composti farmaceutici.
IT1320176B1 (it) *	2000-12-22	2003-11-26	Nicox Sa	Dispersioni solide di principi attivi nitrati.
EP1336602A1 (en) *	2002-02-13	2003-08-20	Giovanni Scaramuzzino	Nitrate prodrugs able to release nitric oxide in a controlled and selective way and their use for prevention and treatment of inflammatory, ischemic and proliferative diseases

2002
- 2002-01-29 IT IT2002MI000148A patent/ITMI20020148A1/it unknown
2003
- 2003-01-16 JP JP2003564063A patent/JP2005516070A/ja active Pending
- 2003-01-16 EP EP03734674A patent/EP1470150A2/en not_active Ceased
- 2003-01-16 AU AU2003210161A patent/AU2003210161B2/en not_active Ceased
- 2003-01-16 CA CA002473249A patent/CA2473249A1/en not_active Abandoned
- 2003-01-16 MX MXPA04007337A patent/MXPA04007337A/es unknown
- 2003-01-16 US US10/501,335 patent/US20060052594A1/en not_active Abandoned
- 2003-01-16 WO PCT/EP2003/000394 patent/WO2003064443A2/en not_active Ceased
- 2003-01-16 NZ NZ534147A patent/NZ534147A/en not_active IP Right Cessation
- 2003-01-16 PL PL03370457A patent/PL370457A1/xx unknown
- 2003-01-16 BR BR0307027-1A patent/BR0307027A/pt not_active IP Right Cessation
2004
- 2004-08-27 NO NO20043595A patent/NO327364B1/no not_active IP Right Cessation
2008
- 2008-12-15 AU AU2008258133A patent/AU2008258133A1/en not_active Abandoned
2009
- 2009-05-12 US US12/464,562 patent/US20090221543A1/en not_active Abandoned

Also Published As

Publication number	Publication date
WO2003064443A3 (en)	2004-02-26
AU2003210161B2 (en)	2008-12-04
AU2008258133A1 (en)	2009-01-08
NZ534147A (en)	2006-09-29
US20090221543A1 (en)	2009-09-03
MXPA04007337A (es)	2004-11-26
CA2473249A1 (en)	2003-08-07
JP2005516070A (ja)	2005-06-02
BR0307027A (pt)	2004-11-03
ITMI20020148A1 (it)	2003-07-29
ITMI20020148A0 (it)	2002-01-29
EP1470150A2 (en)	2004-10-27
WO2003064443A2 (en)	2003-08-07
PL370457A1 (en)	2005-05-30
US20060052594A1 (en)	2006-03-09
NO327364B1 (no)	2009-06-15

Legal Events

Date	Code	Title	Description
2011-09-05	MM1K	Lapsed by not paying the annual fees

Publication	Publication Date	Title
NO20044588L (no)	2004-10-25	Nye forbindelser
NO20044432L (no)	2004-10-19	Nye forbindelser
NO20055219D0 (no)	2005-11-04	Nye forbindelser
NO20054224D0 (no)	2005-09-12	Nye 2-pyridinkarboksamidderivater
DK1523493T3 (da)	2013-12-02	Nye tubulysinanaloge
NO20035428D0 (no)	2003-12-05	Nye anti-ineffektiver
NO20034308D0 (no)	2003-09-26	Nye tyrokinase-inhibitorer
NO20034992D0 (no)	2003-11-10	Nye 4-aninlinokinolin-3-karboksamider
EP1494997A4 (en)	2007-04-11	SUBSTITUTED ARYLAMID
NO20054005D0 (no)	2005-08-29	Nye arylpiperazinylforbindelser
NO20043595L (no)	2004-10-20	Nye kortikosteroider
NO20044046L (no)	2004-11-15	Substituerte hydroksyetylaminer
DE60304683D1 (de)	2006-05-24	Auftrennwerkzeug
DK1704148T3 (da)	2011-06-14	Nye kondenserede pyrrolocarbazoler
DK1492934T3 (da)	2010-10-04	Dørenhed
NO20041185L (no)	2004-03-19	Nye sykloheksylsulfoner
ATE496887T1 (de)	2011-02-15	Substituierte 5-aminomethyl-1h-pyrrol-2-carbons ureamide
NO20026285D0 (no)	2002-12-30	Nye peptider
NO20044098L (no)	2004-10-04	Nye forbindelser
NO20025902D0 (no)	2002-12-09	Nye fenylpiperaziner
NO20054172D0 (no)	2005-09-07	Nye blandinger
ITMI20021327A1 (it)	2003-12-15	Nuove ossialchilpiperazine
ITMI20021329A1 (it)	2003-12-15	Nuove ossialchilammine sostituite
DE50306228D1 (de)	2007-02-15	Substituierte benzdioxepine
NO20050026L (no)	2005-02-21	Nye benzodioksoler