NO20043988L - Fremgangsmate for fremstilling av chirale 1,4-substituerte piperaziner - Google Patents
Fremgangsmate for fremstilling av chirale 1,4-substituerte piperazinerInfo
- Publication number
- NO20043988L NO20043988L NO20043988A NO20043988A NO20043988L NO 20043988 L NO20043988 L NO 20043988L NO 20043988 A NO20043988 A NO 20043988A NO 20043988 A NO20043988 A NO 20043988A NO 20043988 L NO20043988 L NO 20043988L
- Authority
- NO
- Norway
- Prior art keywords
- chiral
- preparation
- substituted piperazines
- piperazines
- substituted
- Prior art date
Links
- 150000004885 piperazines Chemical class 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/10—Spiro-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
- C07C229/06—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton
- C07C229/10—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton the nitrogen atom of the amino group being further bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings
- C07C229/12—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton the nitrogen atom of the amino group being further bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings to carbon atoms of acyclic carbon skeletons
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof
- C07C309/01—Sulfonic acids
- C07C309/02—Sulfonic acids having sulfo groups bound to acyclic carbon atoms
- C07C309/03—Sulfonic acids having sulfo groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
- C07C309/06—Sulfonic acids having sulfo groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton containing halogen atoms, or nitro or nitroso groups bound to the carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D319/10—1,4-Dioxanes; Hydrogenated 1,4-dioxanes
- C07D319/14—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems
- C07D319/16—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C07D319/18—Ethylenedioxybenzenes, not substituted on the hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/10—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/07—Optical isomers
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Neurology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
- Pyridine Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US36345802P | 2002-03-12 | 2002-03-12 | |
| PCT/US2003/007176 WO2003078420A2 (en) | 2002-03-12 | 2003-03-10 | Process for making chiral 1,4-disubstituted piperazines |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NO20043988L true NO20043988L (no) | 2004-09-23 |
Family
ID=28041772
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20043988A NO20043988L (no) | 2002-03-12 | 2004-09-23 | Fremgangsmate for fremstilling av chirale 1,4-substituerte piperaziner |
Country Status (20)
| Country | Link |
|---|---|
| US (3) | US7019137B2 (no) |
| EP (1) | EP1483256A2 (no) |
| JP (1) | JP2005527530A (no) |
| KR (1) | KR20040091119A (no) |
| CN (2) | CN101492383A (no) |
| AR (1) | AR038931A1 (no) |
| AU (1) | AU2003220110B2 (no) |
| BR (1) | BR0308347A (no) |
| CA (1) | CA2477906A1 (no) |
| CR (1) | CR7428A (no) |
| EC (1) | ECSP045292A (no) |
| IL (1) | IL163828A0 (no) |
| MX (1) | MXPA04008730A (no) |
| NO (1) | NO20043988L (no) |
| NZ (1) | NZ535169A (no) |
| RU (2) | RU2315044C2 (no) |
| TW (1) | TW200304825A (no) |
| UA (1) | UA79774C2 (no) |
| WO (1) | WO2003078420A2 (no) |
| ZA (1) | ZA200408205B (no) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2323451T7 (es) | 2001-07-20 | 2011-08-01 | Psychogenics Inc. | Tratamiento para el trastorno de hiperactividad con deficit de atencion. |
| US7361773B2 (en) * | 2002-03-12 | 2008-04-22 | Wyeth | Preparation of N1-(2'-pyridyl)-1,2-propanediamine sulfamic acid and its use in the synthesis of biologically active piperazines |
| BR0308347A (pt) * | 2002-03-12 | 2005-01-25 | Wyeth Corp | Processo para fabricação de piperazinas 1,4-dissubstituìdas quirais |
| US20050209245A1 (en) * | 2004-03-19 | 2005-09-22 | Wyeth | Process for preparing N-aryl-piperazine derivatives |
| US20050215561A1 (en) * | 2004-03-19 | 2005-09-29 | Krishnendu Ghosh | Pharmaceutical dosage forms and compositions |
| US20070099931A1 (en) * | 2004-03-19 | 2007-05-03 | Wyeth | Pharmaceutical dosage forms and compositions |
| WO2008117269A2 (en) | 2007-03-28 | 2008-10-02 | Atir Holding S.A. | Heterotri cyciii c compounds as serotonergic and/or dopaminergic agents and uses thereof |
| CN108627380B (zh) * | 2017-03-15 | 2020-10-20 | 中国人民解放军军事医学科学院毒物药物研究所 | 去除或减少有毒物质的方法以及检测有毒物质的方法 |
Family Cites Families (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE960203C (de) * | 1953-12-25 | 1957-03-21 | Yoshitomi Pharmaceutical | Verfahren zur Herstellung von N-substituierten Aminocarbonsaeureestern |
| AU577802B2 (en) * | 1983-10-17 | 1988-10-06 | Duphar International Research B.V. | Blood-pressure lowering piperazine derivatives |
| EP0189612B1 (en) | 1984-12-21 | 1992-11-04 | Duphar International Research B.V | New pharmaceutical compositions having a psychotropic activity |
| JPH01125357A (ja) | 1987-11-06 | 1989-05-17 | Dainippon Pharmaceut Co Ltd | トリペプチドの誘導体 |
| MX9201991A (es) | 1991-05-02 | 1992-11-01 | Jonh Wyeth & Brother Limited | Derivados de piperazina y procedimiento para su preparacion. |
| GB9125900D0 (en) * | 1991-12-05 | 1992-02-05 | Wyeth John & Brother Ltd | Piperazine derivatives |
| JP3367104B2 (ja) * | 1992-04-13 | 2003-01-14 | 藤沢薬品工業株式会社 | 抗菌剤としての置換された３−ピロリジニルチオ−カルバペネム化合物 |
| GB9208740D0 (en) * | 1992-04-23 | 1992-06-10 | Glaxo Group Ltd | Chemical compounds |
| WO1994024115A1 (fr) | 1993-04-16 | 1994-10-27 | Santen Pharmaceutical Co., Ltd. | Nouveau derive de piperazine |
| GB9411099D0 (en) | 1994-06-03 | 1994-07-27 | Wyeth John & Brother Ltd | Piperazine derivatives |
| JPH10504275A (ja) | 1994-06-03 | 1998-04-28 | ジョン・ワイス・アンド・ブラザー・リミテッド | ピペラジン誘導体を製造するための新規な方法および中間体 |
| GB9413772D0 (en) | 1994-07-08 | 1994-08-24 | Wyeth John & Brother Ltd | 5-HT1A ligands |
| NZ284851A (en) * | 1994-08-05 | 1998-07-28 | Pfizer | 1-[3-(piperazin-1-yl)-prop-1-yl] benzimidazole derivatives and their use in the treatment of cns disorders |
| US5681958A (en) * | 1995-06-07 | 1997-10-28 | Shaman Pharmaceuticals, Inc. | Cryptolepine analogs with hypoglycemic activity |
| US5889010A (en) * | 1995-05-18 | 1999-03-30 | Pfizer Inc. | Benzimidazole derivatives having dopaminergic activity |
| GB9514901D0 (en) | 1995-07-20 | 1995-09-20 | American Home Prod | Piperazine derivatives |
| JP2000508319A (ja) | 1996-04-10 | 2000-07-04 | メルク エンド カンパニー インコーポレーテッド | αｖβ３拮抗薬 |
| US6271234B1 (en) | 1997-08-01 | 2001-08-07 | Recordati S.A., Chemical And Pharmaceutical Company | 1,4-disubstituted piperazines |
| JPH11106381A (ja) * | 1997-09-30 | 1999-04-20 | Ss Pharmaceut Co Ltd | クロメン誘導体及びその塩並びにこれを含有する医薬 |
| US6469007B2 (en) | 2000-11-28 | 2002-10-22 | Wyeth | Serotonergic agents |
| IL161573A0 (en) * | 2001-11-30 | 2004-09-27 | Schering Corp | [1,2,4]-TRIAZOLE BICYCLIC ADENOSINE A2a RECEPTOR ANTAGONISTS |
| BR0308347A (pt) | 2002-03-12 | 2005-01-25 | Wyeth Corp | Processo para fabricação de piperazinas 1,4-dissubstituìdas quirais |
| US7091349B2 (en) * | 2002-03-12 | 2006-08-15 | Wyeth | Process for synthesizing N-aryl piperazines with chiral N′-1-[benzoyl(2-pyridyl)amino]-2-propane substitution |
| ES2329122T3 (es) * | 2002-03-12 | 2009-11-23 | Wyeth | Procedimiento para sintetizar n-aril piperazinas quirales. |
| JP4397693B2 (ja) | 2002-03-12 | 2010-01-13 | ワイス | Ｎ１−（２’−ピリジル）−１，２−アルカンジアミンスルファミン酸の合成および生物学的に活性なピペラジンの合成におけるその使用 |
| US7361773B2 (en) * | 2002-03-12 | 2008-04-22 | Wyeth | Preparation of N1-(2'-pyridyl)-1,2-propanediamine sulfamic acid and its use in the synthesis of biologically active piperazines |
-
2003
- 2003-03-10 BR BR0308347-0A patent/BR0308347A/pt not_active IP Right Cessation
- 2003-03-10 KR KR10-2004-7014163A patent/KR20040091119A/ko not_active Ceased
- 2003-03-10 WO PCT/US2003/007176 patent/WO2003078420A2/en not_active Ceased
- 2003-03-10 CN CNA2008101786904A patent/CN101492383A/zh not_active Withdrawn
- 2003-03-10 AU AU2003220110A patent/AU2003220110B2/en not_active Expired - Fee Related
- 2003-03-10 MX MXPA04008730A patent/MXPA04008730A/es active IP Right Grant
- 2003-03-10 IL IL16382803A patent/IL163828A0/xx unknown
- 2003-03-10 CN CNB038059169A patent/CN100451014C/zh not_active Expired - Fee Related
- 2003-03-10 JP JP2003576425A patent/JP2005527530A/ja active Pending
- 2003-03-10 RU RU2004130313/04A patent/RU2315044C2/ru not_active IP Right Cessation
- 2003-03-10 CA CA002477906A patent/CA2477906A1/en not_active Withdrawn
- 2003-03-10 EP EP03716403A patent/EP1483256A2/en not_active Withdrawn
- 2003-03-10 US US10/384,837 patent/US7019137B2/en not_active Expired - Fee Related
- 2003-03-10 NZ NZ535169A patent/NZ535169A/xx unknown
- 2003-03-10 TW TW092105096A patent/TW200304825A/zh unknown
- 2003-03-11 AR ARP030100832A patent/AR038931A1/es unknown
- 2003-10-03 UA UA20041008215A patent/UA79774C2/uk unknown
-
2004
- 2004-08-24 CR CR7428A patent/CR7428A/es not_active Application Discontinuation
- 2004-09-10 EC EC2004005292A patent/ECSP045292A/es unknown
- 2004-09-23 NO NO20043988A patent/NO20043988L/no not_active Application Discontinuation
- 2004-10-11 ZA ZA200408205A patent/ZA200408205B/en unknown
-
2005
- 2005-06-07 US US11/147,055 patent/US7256289B2/en not_active Expired - Fee Related
-
2007
- 2007-07-06 RU RU2007125687/04A patent/RU2007125687A/ru not_active Application Discontinuation
- 2007-08-08 US US11/891,062 patent/US20080058543A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| CR7428A (es) | 2008-09-23 |
| US7019137B2 (en) | 2006-03-28 |
| ZA200408205B (en) | 2007-03-28 |
| US20030208075A1 (en) | 2003-11-06 |
| US7256289B2 (en) | 2007-08-14 |
| RU2004130313A (ru) | 2005-04-10 |
| CA2477906A1 (en) | 2003-09-25 |
| CN101492383A (zh) | 2009-07-29 |
| AR038931A1 (es) | 2005-02-02 |
| CN1642937A (zh) | 2005-07-20 |
| MXPA04008730A (es) | 2004-12-06 |
| WO2003078420A3 (en) | 2004-03-11 |
| NZ535169A (en) | 2006-03-31 |
| RU2007125687A (ru) | 2009-01-20 |
| WO2003078420A2 (en) | 2003-09-25 |
| US20080058543A1 (en) | 2008-03-06 |
| CN100451014C (zh) | 2009-01-14 |
| ECSP045292A (es) | 2004-10-26 |
| IL163828A0 (en) | 2005-12-18 |
| KR20040091119A (ko) | 2004-10-27 |
| AU2003220110A1 (en) | 2003-09-29 |
| UA79774C2 (en) | 2007-07-25 |
| US20050228181A1 (en) | 2005-10-13 |
| AU2003220110B2 (en) | 2009-04-09 |
| JP2005527530A (ja) | 2005-09-15 |
| TW200304825A (en) | 2003-10-16 |
| EP1483256A2 (en) | 2004-12-08 |
| RU2315044C2 (ru) | 2008-01-20 |
| BR0308347A (pt) | 2005-01-25 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC2A | Withdrawal, rejection or dismissal of laid open patent application |