NO20044540L - Kimaer pankreas - Google Patents

Kimaer pankreas

Info

Publication number
NO20044540L
NO20044540L NO20044540A NO20044540A NO20044540L NO 20044540 L NO20044540 L NO 20044540L NO 20044540 A NO20044540 A NO 20044540A NO 20044540 A NO20044540 A NO 20044540A NO 20044540 L NO20044540 L NO 20044540L
Authority
NO
Norway
Prior art keywords
recipient
mammalian
pancreatic
tissue
pancreatic tissue
Prior art date
Application number
NO20044540A
Other languages
English (en)
Norwegian (no)
Inventor
Marc R Hammerman
Original Assignee
Univ Washington
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Washington filed Critical Univ Washington
Publication of NO20044540L publication Critical patent/NO20044540L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2839—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the integrin superfamily
    • C07K16/2845—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the integrin superfamily against integrin beta2-subunit-containing molecules, e.g. CD11, CD18
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/37—Digestive system
    • A61K35/39—Pancreas; Islets of Langerhans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2806—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against CD2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2875—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF/TNF superfamily, e.g. CD70, CD95L, CD153, CD154
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/289—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against CD45
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0676—Pancreatic cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Emergency Medicine (AREA)
  • Physiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Nutrition Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Developmental Biology & Embryology (AREA)
  • Virology (AREA)
  • Epidemiology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
NO20044540A 2002-03-25 2004-10-22 Kimaer pankreas NO20044540L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US36718102P 2002-03-25 2002-03-25
PCT/US2003/009091 WO2003083064A2 (fr) 2002-03-25 2003-03-24 Pancreas chimerique

Publications (1)

Publication Number Publication Date
NO20044540L true NO20044540L (no) 2004-10-22

Family

ID=28675331

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20044540A NO20044540L (no) 2002-03-25 2004-10-22 Kimaer pankreas

Country Status (16)

Country Link
US (2) US7384630B2 (fr)
EP (1) EP1487967B1 (fr)
JP (1) JP2005521497A (fr)
KR (1) KR20040099350A (fr)
CN (1) CN1643133A (fr)
AT (1) ATE484576T1 (fr)
AU (1) AU2003259298B2 (fr)
BR (1) BR0308718A (fr)
CA (1) CA2477538C (fr)
DE (1) DE60334534D1 (fr)
EA (1) EA200401244A1 (fr)
IL (1) IL164250A0 (fr)
MX (1) MXPA04009411A (fr)
NO (1) NO20044540L (fr)
WO (1) WO2003083064A2 (fr)
ZA (1) ZA200406983B (fr)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL165425A0 (en) * 2004-11-28 2006-01-15 Yeda Res & Dev Methods of treating disease by transplantation of developing allogeneic or xenogeneic organs or tissues
US20090155229A1 (en) * 2004-12-06 2009-06-18 Avner Yayon Chondrocyte-based implant for the delivery of therapeutic agents
EP2514315A3 (fr) * 2005-08-24 2012-11-07 Yeda Research and Development Co. Ltd. Cellules tolerogeniques derivees de donneurs universels et destinees a induire une tolerance a la transplantation non syngenique
CA2623106C (fr) 2005-09-19 2013-12-24 Histogenics Corporation Matrice support de cellules dont la densite des pores et la porosite sont definies specifiquement de maniere uniforme verticalement et organisees de maniere non aleatoire, et procede de preparation de celle-ci
US8685107B2 (en) 2007-07-03 2014-04-01 Histogenics Corporation Double-structured tissue implant and a method for preparation and use thereof
US20090054984A1 (en) 2007-08-20 2009-02-26 Histogenics Corporation Method For Use Of A Double-Structured Tissue Implant For Treatment Of Tissue Defects
US8709400B2 (en) * 2009-07-27 2014-04-29 Washington University Inducement of organogenetic tolerance for pancreatic xenotransplant
WO2011016423A1 (fr) * 2009-08-02 2011-02-10 学校法人 東京女子医科大学 Feuillet de cellules de langerhans, procédé de production associé, et application associée
US9420770B2 (en) 2009-12-01 2016-08-23 Indiana University Research & Technology Corporation Methods of modulating thrombocytopenia and modified transgenic pigs
US10077420B2 (en) 2014-12-02 2018-09-18 Histogenics Corporation Cell and tissue culture container

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5804178A (en) * 1986-11-20 1998-09-08 Massachusetts Institute Of Technology Implantation of cell-matrix structure adjacent mesentery, omentum or peritoneum tissue
JPH06503001A (ja) * 1991-08-02 1994-04-07 システミックス，インコーポレイティド 免疫不全宿主における原基移植物
EP0867426B1 (fr) * 1993-09-07 2002-06-26 Gerhard Dr. Gergely Cristaux modifiés d'un acide organique comestible solide
US5560911A (en) * 1993-10-12 1996-10-01 Oklahoma Medical Research Foundation Method of inhibiting acute complement mediated cytotoxicity with anti-idiotypic antibodies
US5629194A (en) * 1994-10-21 1997-05-13 Diacrin, Inc. Isolated porcine pancreatic cells for use in treatment of diseases characterized by insufficient insulin activity
JP2003523323A (ja) 1999-12-06 2003-08-05 ザ ジェネラル ホスピタル コーポレーション 膵臓幹細胞および移植におけるその使用
US20020168371A1 (en) * 2000-05-18 2002-11-14 Michel Awwad Process for reducing antibody response against xenografts
US20030031652A1 (en) * 2001-04-16 2003-02-13 Bernhard Hering Systems and methods for inducing mixed chimerism

Also Published As

Publication number Publication date
BR0308718A (pt) 2005-01-04
US20030198628A1 (en) 2003-10-23
EP1487967A4 (fr) 2005-05-11
JP2005521497A (ja) 2005-07-21
EA200401244A1 (ru) 2005-02-24
KR20040099350A (ko) 2004-11-26
WO2003083064A2 (fr) 2003-10-09
EP1487967B1 (fr) 2010-10-13
CA2477538A1 (fr) 2003-10-09
CA2477538C (fr) 2008-01-29
AU2003259298A1 (en) 2003-10-13
ATE484576T1 (de) 2010-10-15
ZA200406983B (en) 2005-09-22
AU2003259298B2 (en) 2006-08-31
IL164250A0 (en) 2005-12-18
CN1643133A (zh) 2005-07-20
US7384630B2 (en) 2008-06-10
EP1487967A2 (fr) 2004-12-22
DE60334534D1 (de) 2010-11-25
MXPA04009411A (es) 2005-01-25
US20080318202A1 (en) 2008-12-25
WO2003083064A3 (fr) 2004-03-25

Similar Documents

Publication Publication Date Title
MX2009014273A (es) Metodos y composiciones para expansion e implantacion optimizadas de celulas madre mesenquimales.
ATE382681T1 (de) Verbesserung der herzfunktion durch transplantation mesenchymaler stammzellen
WO2010022395A3 (fr) Procédés de reprogrammation de cellules
WO2006042238A3 (fr) Procedes de stockage de matrices tissulaires
TW200503794A (en) Treatment of tissue with undifferentiated mesenchymal cells
ATE484576T1 (de) Chimäre bauchspeicheldrüse
WO2005086860A3 (fr) Procedes d'obtention de cellules produisant de l'insuline
WO2009050742A8 (fr) Utilisation de microvésicules (mvs) pour préparer un médicament ayant une activité d'adjuvant sur la transplantation de cellules endothéliales, en particulier dans le traitement du diabète par une transplantation d'îlots pancréatiques, et procédé associé
EP1910519A4 (fr) Immunophénotype et immunogénicité de cellules dérivées de tissus adipeux humains
IL190693A (en) Substance damage suppressants are implanted after islet transplantation, containing and utilizing antibodies that detect il-6 receptor.
BRPI0519783A2 (pt) composições imunogênicas de pvc2 e métodos de produzir tais composições
DK1248640T3 (da) Xenotransplantation af svineöer og deres fremstilling
MX2021011709A (es) Celulas, tejidos y organos personalizados para trasplante de un donante humanizado, adaptado, designado libre de patogenos (no humano) y metodos y productos relacionados con estos.
WO2006073890A3 (fr) Utilisation de glp-1 et d'agonistes de ce compose pour prevenir l'apoptose de myocytes cardiaques
WO2006107850A3 (fr) Procede de prevention du rejet d'un tissu transplante
GB2397825B (en) Method of producing human beta cell lines
TW200833836A (en) An improved method of cultivating the Cordyceps Militaris by adding sugar cane fiber
JP2005521497A5 (fr)
Jang et al. Genome editing for engineering stem cell-derived pancreatic β cells: recent trends and future perspectives
MX2021009855A (es) Roedores que tienen canales de sodio modificados geneticamente y metodos de uso de los mismos.
SE0401807D0 (sv) Förfaranden och kompositioner för nytillväxt av kryopreserverade tallembryon
PL1664307T3 (pl) Nowy, specyficzny dla bielma promotor roślinny dla roślin uprawnych
WO2006079107A3 (fr) Compositions pour transplantation et procedes de traitement des diabetes
Kim et al. Susceptibility of porcine keratocytes to immune-mediated damage in xeno-related rejection
UA39614A (uk) Спосіб корекції функціонального стану міокарда у лабораторних тварин пізнього онтогенезу

Legal Events

Date Code Title Description
FC2A Withdrawal, rejection or dismissal of laid open patent application