NO20050649L - Nye tiofenylglykosidderivater, fremgangsmate for fremstilling derav, medikamenter omfattende disse forbindelser og anvendelse derav - Google Patents

Nye tiofenylglykosidderivater, fremgangsmate for fremstilling derav, medikamenter omfattende disse forbindelser og anvendelse derav

Info

Publication number: NO20050649L
Authority: NO; Norway
Prior art keywords: compounds; thiophenyl; new; medicaments; preparation
Prior art date: 2002-07-11

Application number

NO20050649A

Other languages

English (en)

Norwegian (no)

Inventor

Heiner Glombik

Hubert Heuer

Werner Kramer

Wendelin Frick

Harm Brummerhop

Oliver Plettenburg

Original Assignee

Aventis Pharma Gmbh

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2002-07-11

Filing date

2005-02-07

Publication date

2005-04-01

2005-02-07 Application filed by Aventis Pharma Gmbh filed Critical Aventis Pharma Gmbh

2005-04-01 Publication of NO20050649L publication Critical patent/NO20050649L/no

Links

150000001875 compounds Chemical class 0.000 title abstract 3
-1 Thiophenyl Glycoside Chemical class 0.000 title abstract 2
229930182470 glycoside Natural products 0.000 title abstract 2
239000003814 drug Substances 0.000 title 1
230000003178 anti-diabetic effect Effects 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Engineering & Computer Science (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Bioinformatics & Cheminformatics (AREA)
Molecular Biology (AREA)
Diabetes (AREA)
Neurology (AREA)
Epidemiology (AREA)
Neurosurgery (AREA)
Hematology (AREA)
Biomedical Technology (AREA)
Rheumatology (AREA)
Genetics & Genomics (AREA)
Biotechnology (AREA)
Biochemistry (AREA)
Physical Education & Sports Medicine (AREA)
Orthopedic Medicine & Surgery (AREA)
Pulmonology (AREA)
Virology (AREA)
Communicable Diseases (AREA)
Oncology (AREA)
Urology & Nephrology (AREA)
Cardiology (AREA)
Psychiatry (AREA)
Immunology (AREA)
Obesity (AREA)
Heart & Thoracic Surgery (AREA)
Tropical Medicine & Parasitology (AREA)
Hospice & Palliative Care (AREA)

NO20050649A 2002-07-11 2005-02-07 Nye tiofenylglykosidderivater, fremgangsmate for fremstilling derav, medikamenter omfattende disse forbindelser og anvendelse derav NO20050649L (no)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
DE10231370A DE10231370B4 (de)	2002-07-11	2002-07-11	Thiophenglycosidderivate, diese Verbindungen enthaltende Arzneimittel und Verfahren zur Herstellung dieser Arzneimittel
PCT/EP2003/006841 WO2004007517A1 (fr)	2002-07-11	2003-06-27	Nouveaux derives de thiophene-glycoside, procede permettant de les produire, medicaments contenant lesdits composes et leur utilisation

Publications (1)

Publication Number	Publication Date
NO20050649L true NO20050649L (no)	2005-04-01

Family

ID=30009905

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO20050649A NO20050649L (no)	2002-07-11	2005-02-07	Nye tiofenylglykosidderivater, fremgangsmate for fremstilling derav, medikamenter omfattende disse forbindelser og anvendelse derav

Country Status (39)

Country	Link
US (2)	US7101856B2 (fr)
EP (4)	EP1523488B1 (fr)
JP (1)	JP4511927B2 (fr)
KR (1)	KR20050021452A (fr)
CN (2)	CN101240000A (fr)
AR (1)	AR040474A1 (fr)
AT (4)	ATE414095T1 (fr)
AU (1)	AU2003246620B2 (fr)
BR (1)	BR0312513A (fr)
CA (1)	CA2493391C (fr)
CR (1)	CR7718A (fr)
CY (1)	CY1108754T1 (fr)
DE (5)	DE10231370B4 (fr)
DK (1)	DK1523488T3 (fr)
EC (1)	ECSP055531A (fr)
ES (1)	ES2316818T3 (fr)
HN (1)	HN2003000215A (fr)
HR (1)	HRP20050014A2 (fr)
IL (2)	IL166058A0 (fr)
JO (1)	JO2707B1 (fr)
MA (1)	MA27366A1 (fr)
ME (1)	MEP60708A (fr)
MX (1)	MXPA05000044A (fr)
MY (1)	MY137039A (fr)
NO (1)	NO20050649L (fr)
OA (1)	OA12880A (fr)
PA (1)	PA8577101A1 (fr)
PE (1)	PE20040655A1 (fr)
PL (1)	PL372931A1 (fr)
PT (1)	PT1523488E (fr)
RS (1)	RS51002B (fr)
RU (1)	RU2317300C2 (fr)
SI (1)	SI1523488T1 (fr)
TN (1)	TNSN05007A1 (fr)
TW (1)	TWI318981B (fr)
UA (1)	UA78823C2 (fr)
UY (1)	UY27891A1 (fr)
WO (1)	WO2004007517A1 (fr)
ZA (1)	ZA200409779B (fr)

Families Citing this family (121)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CN1020944C (zh)	1990-01-30	1993-05-26	阿图尔-费希尔股份公司费希尔厂	紧固件
DE10258008B4 (de) *	2002-12-12	2006-02-02	Sanofi-Aventis Deutschland Gmbh	Heterocyclische Fluorglycosidderivate, diese Verbindungen enthaltende Arzneimittel und Verfahren zur Herstellung dieser Arzneimittel
DE10308353A1 (de)	2003-02-27	2004-12-02	Aventis Pharma Deutschland Gmbh	Diarylcycloalkylderivate, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
US7439232B2 (en)	2003-04-01	2008-10-21	Taisho Pharmaceutical Co., Ltd.	Heteroaryl 5-thio-β-D-glucopyranoside derivatives and therapeutic agents for diabetes containing the same
MXPA06001274A (es)	2003-08-01	2006-04-11	Tanabe Seiyaku Co	Compuestos novedosos que poseen actividad inhibitoria contra transporador dependiente de sodio.
US8785403B2 (en)	2003-08-01	2014-07-22	Mitsubishi Tanabe Pharma Corporation	Glucopyranoside compound
TW200606129A (en)	2004-07-26	2006-02-16	Chugai Pharmaceutical Co Ltd	Novel cyclohexane derivative, its prodrug, its salt and diabetic therapeutic agent containing the same
WO2006010379A1 (fr)	2004-07-29	2006-02-02	Actelion Pharmaceuticals Ltd.	Nouveaux derives du thiophene utilises comme agents immunosupresseurs
DE102004063099B4 (de) *	2004-12-22	2009-02-12	Sanofi-Aventis Deutschland Gmbh	Verfahren zur Herstellung von Thiophenglycosidderivaten
TW200637869A (en)	2005-01-28	2006-11-01	Chugai Pharmaceutical Co Ltd	The spiroketal derivatives and the use as therapeutical agent for diabetes of the same
MY147375A (en)	2005-01-31	2012-11-30	Mitsubishi Tanabe Pharma Corp	Indole derivatives
AR053329A1 (es) *	2005-01-31	2007-05-02	Tanabe Seiyaku Co	Derivados de indol utiles como inhibidores de los transportadores de glucosa dependientes del sodio (sglt)
KR20080002850A (ko)	2005-03-23	2008-01-04	액테리온 파마슈티칼 리미티드	신규한 티오펜 유도체
US7772191B2 (en)	2005-05-10	2010-08-10	Boehringer Ingelheim International Gmbh	Processes for preparing of glucopyranosyl-substituted benzyl-benzene derivatives and intermediates therein
DE102005026762A1 (de)	2005-06-09	2006-12-21	Sanofi-Aventis Deutschland Gmbh	Azolopyridin-2-on-derivate als Inhibitoren von Lipasen und Phospholipasen
AU2006260573A1 (en) *	2005-06-24	2006-12-28	Actelion Pharmaceuticals Ltd.	Novel thiophene derivatives
KR20080092385A (ko)	2006-01-24	2008-10-15	액테리온 파마슈티칼 리미티드	신규한 피리딘 유도체
PE20080697A1 (es)	2006-05-03	2008-08-05	Boehringer Ingelheim Int	Derivados de benzonitrilo sustituidos con glucopiranosilo, composiciones farmaceuticas que contienen compuestos de este tipo, su uso y procedimiento para su fabricacion
TWI432446B (zh)	2006-07-27	2014-04-01	Chugai Pharmaceutical Co Ltd	稠環螺酮縮醇衍生物、及其做為糖尿病治療藥之使用
TWI403516B (zh)	2006-07-27	2013-08-01	Chugai Pharmaceutical Co Ltd	To replace spirocyclic alcohol derivatives, and its use as a therapeutic agent for diabetes
TWI418556B (zh)	2006-07-27	2013-12-11	Mitsubishi Tanabe Pharma Corp	吲哚衍生物
BRPI0715160A2 (pt)	2006-08-08	2013-06-11	Sanofi Aventis	imidazolidina-2,4-dionas substituÍdas por arilamimoaril-alquil-, processo para preparÁ-las, medicamentos compeendendo estes compostos, e seu uso
CN101522699A (zh)	2006-10-13	2009-09-02	中外制药株式会社	硫葡萄糖螺缩酮衍生物、及其作为糖尿病治疗药的应用
UY30730A1 (es)	2006-12-04	2008-07-03	Mitsubishi Tanabe Pharma Corp	Forma cristalina del hemihidrato de 1-(b (beta)-d-glucopiranosil) -4-metil-3-[5-(4-fluorofenil) -2-tienilmetil]benceno
JP5298025B2 (ja)	2006-12-04	2013-09-25	ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ	抗糖尿病薬としてのチエニル含有グリコピラノシル誘導体
EP2025674A1 (fr)	2007-08-15	2009-02-18	sanofi-aventis	Tetrahydronaphthaline substituée, son procédé de fabrication et son utilisation en tant que médicament
PE20090938A1 (es)	2007-08-16	2009-08-08	Boehringer Ingelheim Int	Composicion farmaceutica que comprende un derivado de benceno sustituido con glucopiranosilo
CN101801371B (zh)	2007-09-10	2012-11-28	詹森药业有限公司	可用作sglt抑制剂的化合物的制备方法
CL2008003653A1 (es)	2008-01-17	2010-03-05	Mitsubishi Tanabe Pharma Corp	Uso de un inhibidor de sglt derivado de glucopiranosilo y un inhibidor de dppiv seleccionado para tratar la diabetes; y composicion farmaceutica.
WO2009138195A2 (fr) *	2008-05-16	2009-11-19	Sanofi-Aventis Deutschland Gmbh	Utilisation de dérivés de thiophène-glycoside dans la production de médicaments destinés au traitement de l’hypertension
WO2010003624A2 (fr)	2008-07-09	2010-01-14	Sanofi-Aventis	Composés hétérocycliques, leurs procédés de préparation, médicaments comprenant lesdits composés et leur utilisation
MX2011002166A (es) *	2008-08-28	2011-04-07	Pfizer	Derivados de dioxa-biciclo[3.2.1]octano-2,3,1-triol.
US9056850B2 (en)	2008-10-17	2015-06-16	Janssen Pharmaceutica N.V.	Process for the preparation of compounds useful as inhibitors of SGLT
WO2010068601A1 (fr)	2008-12-08	2010-06-17	Sanofi-Aventis	Hydrate de fluoroglycoside hétéroaromatique cristallin, ses procédés de fabrication, ses procédés d'utilisation et compositions pharmaceutiques le contenant
PL2395983T3 (pl)	2009-02-13	2020-09-07	Boehringer Ingelheim International Gmbh	Kompozycja farmaceutyczna zawierająca inhibitor sglt2, inhibitor dpp-iv i ewentualnie dalszy środek przeciwcukrzycowy oraz jej zastosowania
MY161472A (en)	2009-02-13	2017-04-14	Boehringer Ingelheim Int	Sglt-2 inhibitor for treating type 1 diabetes mellitus, type 2 diabetes mellitus, impaired glucose tolerance or hyperglycemia
US20110009347A1 (en)	2009-07-08	2011-01-13	Yin Liang	Combination therapy for the treatment of diabetes
KR101532412B1 (ko)	2009-07-10	2015-06-29	얀센 파마슈티카 엔.브이.	1-(β-Ｄ-글루코피라노실)-4-메틸-3-(5-(4-플루오로페닐)-2-티에닐메틸) 벤젠의 결정화 방법
DK2470552T3 (en)	2009-08-26	2014-02-17	Sanofi Sa	NOVEL, CRYSTALLINE, heteroaromatic FLUORGLYCOSIDHYDRATER, MEDICINES COVERING THESE COMPOUNDS AND THEIR USE
BR112012007085B8 (pt)	2009-09-30	2021-05-25	Boehringer Ingelheim Int	processos para a preparação de derivados de benzil-benzeno substituídos com glicopiranosila
HUE029381T2 (en)	2009-09-30	2017-02-28	Boehringer Ingelheim Int	Method for the preparation of a crystalline form of 1-chloro-4-(beta-d-glucopyranos-1-yl)-2-(4-((s)-tetrahydrofuran-3-yloxy)benzyl)benzene
US10610489B2 (en)	2009-10-02	2020-04-07	Boehringer Ingelheim International Gmbh	Pharmaceutical composition, pharmaceutical dosage form, process for their preparation, methods for treating and uses thereof
SG10201500258WA (en)	2009-10-14	2015-03-30	Janssen Pharmaceutica Nv	Process for the preparation of compounds useful as inhibitors of sglt2
US8163704B2 (en)	2009-10-20	2012-04-24	Novartis Ag	Glycoside derivatives and uses thereof
KR20120087950A (ko)	2009-10-20	2012-08-07	노파르티스 아게	글리코시드 유도체 및 그의 용도
NZ599945A (en)	2009-11-02	2014-05-30	Pfizer	Dioxa-bicyclo[3.2.1]octane-2,3,4-triol derivatives
WO2011107494A1 (fr)	2010-03-03	2011-09-09	Sanofi	Nouveaux dérivés aromatiques de glycoside, médicaments contenants ces composés, et leur utilisation
US20140088027A1 (en) *	2010-03-30	2014-03-27	Boehringer Ingelheim International Gmbh	Pharmaceutical composition comprising an sglt2 inhibitor and a ppar- gamma agonist and uses thereof
MX2012011631A (es)	2010-04-06	2013-01-18	Arena Pharm Inc	Moduladores del receptor gpr119 y el tratamiento de trastornos relacionados con el mismo.
LT2568988T (lt)	2010-05-11	2016-09-12	Janssen Pharmaceutica, N.V.	Farmacinės kompozicijos, apimančios 1-(beta-d-gliukopiranozil)-2-tienilmetilbenzeno darinius kaip sglt inhibitorius
US8933024B2 (en)	2010-06-18	2015-01-13	Sanofi	Azolopyridin-3-one derivatives as inhibitors of lipases and phospholipases
US8530413B2 (en)	2010-06-21	2013-09-10	Sanofi	Heterocyclically substituted methoxyphenyl derivatives with an oxo group, processes for preparation thereof and use thereof as medicaments
TW201221505A (en)	2010-07-05	2012-06-01	Sanofi Sa	Aryloxyalkylene-substituted hydroxyphenylhexynoic acids, process for preparation thereof and use thereof as a medicament
TW201215387A (en)	2010-07-05	2012-04-16	Sanofi Aventis	Spirocyclically substituted 1,3-propane dioxide derivatives, processes for preparation thereof and use thereof as a medicament
TW201215388A (en)	2010-07-05	2012-04-16	Sanofi Sa	(2-aryloxyacetylamino)phenylpropionic acid derivatives, processes for preparation thereof and use thereof as medicaments
MX2013003184A (es)	2010-09-22	2013-06-07	Arena Pharm Inc	Moduladores del receptor gpr119 y el tratamiento de transtornos relacionados con el mismo.
US20120283169A1 (en)	2010-11-08	2012-11-08	Boehringer Ingelheim International Gmbh	Pharmaceutical composition, methods for treating and uses thereof
WO2012097052A2 (fr) *	2011-01-11	2012-07-19	Intertech Bio, Llc	Composés à base de monosaccharides pour le traitement de maladies dermatologiques prolifératives et inflammatoires
US20130035281A1 (en)	2011-02-09	2013-02-07	Boehringer Ingelheim International Gmbh	Pharmaceutical composition, methods for treating and uses thereof
UY33937A (es)	2011-03-07	2012-09-28	Boehringer Ingelheim Int	Composiciones farmacéuticas que contienen inhibidores de dpp-4 y/o sglt-2 y metformina
WO2012120058A1 (fr)	2011-03-08	2012-09-13	Sanofi	Dérivés d'oxathiazine substitués par des groupes benzyle ou hétérométhylène, leur procédé de production, leur utilisation comme médicament ainsi que produits pharmaceutiques les contenant et leur utilisation
US8710050B2 (en)	2011-03-08	2014-04-29	Sanofi	Di and tri- substituted oxathiazine derivatives, method for the production, method for the production thereof, use thereof as medicine and drug containing said derivatives and use thereof
EP2766349B1 (fr)	2011-03-08	2016-06-01	Sanofi	Dérivés d'oxathiazine substitués par des carbocycles ou des hétérocycles, leur procédé de préparation, médicaments contenant ces composés et leur utilisation
WO2012120056A1 (fr)	2011-03-08	2012-09-13	Sanofi	Dérivés oxathiazine tétra-substitués, procédé pour leur préparation, utilisation en tant que médicament, agent pharmaceutique contenant ces dérivés et utilisation
WO2012120050A1 (fr)	2011-03-08	2012-09-13	Sanofi	Nouveaux dérivés phényl-oxathiazine substitués, procédé pour leur préparation, médicaments contenant ces composés et leur utilisation
EP2683703B1 (fr)	2011-03-08	2015-05-27	Sanofi	Nouveaux dérivés phényl-oxathiazine substitués, procédé pour leur préparation, agent pharmaceutique contenant ces composés et leur utilisation
US8809325B2 (en)	2011-03-08	2014-08-19	Sanofi	Benzyl-oxathiazine derivatives substituted with adamantane and noradamantane, medicaments containing said compounds and use thereof
EP2683704B1 (fr)	2011-03-08	2014-12-17	Sanofi	Dérivés oxathiazine ramifiés, procédé pour leur préparation, utilisation en tant que médicament, agents pharmaceutiques contenant ces dérivés et leur utilisation
WO2012120054A1 (fr)	2011-03-08	2012-09-13	Sanofi	Dérivés oxathiazine di- et tri-substitués, procédé pour leur préparation, utilisation en tant que médicament, agent pharmaceutique contenant ces dérivés et utilisation
WO2012135570A1 (fr)	2011-04-01	2012-10-04	Arena Pharmaceuticals, Inc.	Modulateurs du récepteur gpr119 et traitement de troubles qui lui sont associés
AU2012241897C1 (en)	2011-04-13	2017-05-11	Janssen Pharmaceutica Nv	Process for the preparation of compounds useful as inhibitors of SGLT2
CN103619862A (zh)	2011-04-14	2014-03-05	诺瓦提斯公司	糖苷衍生物及其用途
US8614195B2 (en)	2011-04-14	2013-12-24	Novartis Ag	Glycoside derivatives and uses thereof
WO2012145361A1 (fr)	2011-04-19	2012-10-26	Arena Pharmaceuticals, Inc.	Modulateurs du récepteur gpr119 et traitement de troubles liés à celui-ci
US20140051714A1 (en)	2011-04-22	2014-02-20	Arena Pharmaceuticals, Inc.	Modulators Of The GPR119 Receptor And The Treatment Of Disorders Related Thereto
US20140038889A1 (en)	2011-04-22	2014-02-06	Arena Pharmaceuticals, Inc.	Modulators Of The GPR119 Receptor And The Treatment Of Disorders Related Thereto
TWI542596B (zh)	2011-05-09	2016-07-21	健生藥品公司	（２ｓ,３ｒ,４ｒ,５ｓ,６ｒ）－２－（３－（（５－（４－氟苯基）噻吩－２－基）甲基）－４－甲基苯基）－６－（羥甲基）四氫－２ｈ－哌喃－３,４,５－三醇之ｌ－脯胺酸及檸檬酸共晶體
EA201301354A1 (ru)	2011-06-03	2014-05-30	Бёрингер Ингельхайм Интернациональ Гмбх	Ингибиторы sglt-2, предназначенные для лечения метаболических нарушений у пациентов, леченных нейролептиками
WO2012170702A1 (fr)	2011-06-08	2012-12-13	Arena Pharmaceuticals, Inc.	Modulateurs du récepteur gpr119 et traitement de troubles associés à celui-ci
WO2013037390A1 (fr)	2011-09-12	2013-03-21	Sanofi	Dérivés amides d'acide 6-(4-hydroxyphényl)-3-styryl-1h-pyrazolo[3,4-b]pyridine-4-carboxylique en tant qu'inhibiteurs de kinase
WO2013045413A1 (fr)	2011-09-27	2013-04-04	Sanofi	Dérivés d'amide d'acide 6-(4-hydroxyphényl)-3-alkyl-1h-pyrazolo[3,4-b] pyridine-4-carboxylique utilisés comme inhibiteurs de kinase
WO2013055910A1 (fr)	2011-10-12	2013-04-18	Arena Pharmaceuticals, Inc.	Modulateurs du récepteur gpr119 et traitement de troubles associés
US9555001B2 (en)	2012-03-07	2017-01-31	Boehringer Ingelheim International Gmbh	Pharmaceutical composition and uses thereof
US9192617B2 (en)	2012-03-20	2015-11-24	Boehringer Ingelheim International Gmbh	Pharmaceutical composition, methods for treating and uses thereof
WO2014074668A1 (fr)	2012-11-08	2014-05-15	Arena Pharmaceuticals, Inc.	Modulateurs de gpr119 et traitement de troubles associés à ceux-ci
EP2774619B1 (fr)	2013-03-04	2016-05-18	BioActive Food GmbH	Composition pour le traitement de pathologies hyperglycémiques
PT3466431T (pt)	2013-03-14	2024-01-26	Msd Int Gmbh	Formas cristalinas e métodos para preparação de inibidores de sglt2
EP4245765A3 (fr)	2013-04-04	2024-03-20	Boehringer Ingelheim Vetmedica GmbH	Traitement de troubles metaboliques chez des animaux equins
US20140303097A1 (en)	2013-04-05	2014-10-09	Boehringer Ingelheim International Gmbh	Pharmaceutical composition, methods for treating and uses thereof
EP3939595A1 (fr)	2013-04-05	2022-01-19	Board of Regents, The University of Texas System	Esters de 2-désoxy-monosaccharides ayant une activité antiproliférative
HRP20190101T1 (hr)	2013-04-05	2019-03-08	Boehringer Ingelheim International Gmbh	Terapeutske uporabe empagliflozina
US11813275B2 (en)	2013-04-05	2023-11-14	Boehringer Ingelheim International Gmbh	Pharmaceutical composition, methods for treating and uses thereof
CA2812519A1 (fr)	2013-04-05	2014-10-05	Boehringer Ingelheim International Gmbh	Composition pharmaceutique, procedes pour le traitement et utilisations de celle-ci
KR102309654B1 (ko)	2013-04-18	2021-10-08	베링거 인겔하임 인터내셔날 게엠베하	약제학적 조성물, 치료 방법 및 이의 용도
ES2969764T3 (es)	2013-12-17	2024-05-22	Boehringer Ingelheim Vetmedica Gmbh	Un inhibidor de SGLT-2 para usar en el tratamiento de un trastorno metabólico en animales felinos
CN115282284A (zh)	2014-01-23	2022-11-04	勃林格殷格翰动物保健有限公司	犬科动物中代谢紊乱的治疗
ES2811261T3 (es)	2014-04-01	2021-03-11	Boehringer Ingelheim Vetmedica Gmbh	Tratamiento de trastornos metabólicos en animales equinos
EP2944311A1 (fr)	2014-05-16	2015-11-18	BioActive Food GmbH	Combinaison de substances biologiques actives destinée au traitement de pathologies hypoglycémiques
HUE068152T2 (hu)	2014-09-25	2024-12-28	Boehringer Ingelheim Vetmedica Gmbh	SGLT2-gátlók és dopamin agonisták kombinációs kezelése anyagcserezavarok megelõzésére lófélékben
CN104478968A (zh) *	2015-01-14	2015-04-01	佛山市赛维斯医药科技有限公司	含噻唑基的o-半乳糖苷衍生物、其制备方法和用途
CN104478966A (zh) *	2015-01-14	2015-04-01	佛山市赛维斯医药科技有限公司	含苯胺噻唑基的o-半乳糖苷衍生物、其制备方法和用途
US20170071970A1 (en)	2015-09-15	2017-03-16	Janssen Pharmaceutica Nv	Co-therapy comprising canagliflozin and phentermine for the treatment of obesity and obesity related disorders
EA201990951A1 (ru)	2016-10-19	2019-11-29		Комбинации, содержащие ssao/vap-1 ингибитор и sglt2-ингибитор, и их применение
CA3039745A1 (fr)	2016-11-10	2018-05-17	Boehringer Ingelheim International Gmbh	Composition pharmaceutique, methodes de traitement et leurs utilisations
CN111989103A (zh)	2018-04-17	2020-11-24	勃林格殷格翰国际有限公司	药物组合物、其治疗方法和用途
AU2019318209B2 (en)	2018-08-10	2025-09-25	Diapin Therapeutics, Llc	Tri-peptides and treatment of metabolic, cardiovascular and inflammatory disorders
WO2020039394A1 (fr)	2018-08-24	2020-02-27	Novartis Ag	Nouvelles combinaisons de médicaments
SG11202102440SA (en)	2018-10-29	2021-04-29	Boehringer Ingelheim Int	Pyridinyl sulfonamide derivatives, pharmaceutical compositions and uses thereof
WO2020089025A1 (fr)	2018-10-29	2020-05-07	Boehringer Ingelheim International Gmbh	Dérivés de pyridinyl sulfonamide, compositions pharmaceutiques et leurs utilisations
CN114727624A (zh)	2019-11-28	2022-07-08	勃林格殷格翰动物保健有限公司	Sglt-2抑制剂在非人哺乳动物的停奶中的用途
KR20220143732A (ko)	2020-02-17	2022-10-25	베링거잉겔하임베트메디카게엠베하	고양이과에서 심장 질환을 예방 및/또는 치료하기 위한 sglt-2 억제제의 사용
EP4376819A1 (fr)	2021-07-28	2024-06-05	Boehringer Ingelheim Vetmedica GmbH	Utilisation d'inhibiteurs de sglt-2 pour la prévention et/ou le traitement de l'hypertension chez des mammifères non humains
MX2024001184A (es)	2021-07-28	2024-02-27	Boehringer Ingelheim Vetmedica Gmbh	Uso de inhibidores de sglt-2 para la prevencion y/o tratamiento de cardiopatias en mamiferos no humanos, que excluye felinos, en particular, caninos.
MX2024001185A (es)	2021-07-28	2024-02-27	Boehringer Ingelheim Vetmedica Gmbh	Uso de inhibidores de sglt-2 para la prevencion y/o tratamiento de enfermedades renales en mamiferos no humanos.
IL314031A (en)	2021-12-30	2024-09-01	Newamsterdam Pharma B V	Obicetrapib and sglt2 inhibitor combination
EP4531810A1 (fr)	2022-05-25	2025-04-09	Boehringer Ingelheim Vetmedica GmbH	Compositions pharmaceutiques aqueuses comprenant des inhibiteurs de sglt-2
KR20240109921A (ko)	2023-01-05	2024-07-12	아주대학교산학협력단	Gptc 제조방법
US20240307628A1 (en)	2023-03-06	2024-09-19	Boehringer Ingelheim Vetmedica Gmbh	Systems and methods for delivery of liquid pharmaceutical compositions in particular comprising one or more sglt-2 inhibitor(s)
EP4701626A1 (fr)	2023-04-24	2026-03-04	NewAmsterdam Pharma B.V.	Combinaison d'inhibiteur de sglt2 et d'obicetrapib amorphe
WO2024240632A1 (fr)	2023-05-24	2024-11-28	Boehringer Ingelheim Vetmedica Gmbh	Polythérapie et/ou prévention de maladies cardiaques chez des mammifères non humains comprenant un ou plusieurs inhibiteurs de sglt -2 et du pimobendane et/ou du telmisartan
KR20260019532A (ko)	2023-05-24	2026-02-10	베링거잉겔하임베트메디카게엠베하	하나 이상의 sglt-2 억제제와 텔미사르탄을 포함하는 비인간 포유류의 신장 질환 및/또는 고혈압의 병용 치료 및/또는 예방

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CA165448A (fr)	1914-10-23	1915-10-12	Otto F. Hornschuch	Passe-carreau
FR2663336B1 (fr)	1990-06-18	1992-09-04	Adir	Nouveaux derives peptidiques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.
CZ220498A3 (cs)	1996-01-17	1998-11-11	Novo Nordisk A/S	Deriváty 1,2,4-thiadiazinu a 1,4-thiazinu, příprava a použití
JP3149958B2 (ja)	1996-08-30	2001-03-26	ノボノルディスクアクティーゼルスカブ	Ｇｌｐ―１誘導体
DE69723869T2 (de)	1996-12-31	2004-04-22	Dr. Reddy's Laboratories Ltd.	Heterozyklische verbindungen, verfahren zu ihrer herstellung, pharmazeutische zusammensetzungen die diese enthalten und ihre anwendung in der behandlung von diabetis und verwandten krankheiten
DE19726167B4 (de)	1997-06-20	2008-01-24	Sanofi-Aventis Deutschland Gmbh	Insulin, Verfahren zu seiner Herstellung und es enthaltende pharmazeutische Zubereitung
EP1000066A1 (fr)	1997-07-16	2000-05-17	Novo Nordisk A/S	Derives de 1,2,4-thiadiazine fusionnee, leur preparation et utilisation
CO4970713A1 (es)	1997-09-19	2000-11-07	Sanofi Synthelabo	Derivados de carboxamidotiazoles, su preparacion, composiciones farmaceuticas que los contienen
GB9900416D0 (en)	1999-01-08	1999-02-24	Alizyme Therapeutics Ltd	Inhibitors
PT1177176E (pt)	1999-04-28	2006-08-31	Aventis Pharma Gmbh	Derivados de acidos triarilicos como ligandos de receptores ppar.
IL145922A0 (en)	1999-04-28	2002-07-25	Aventis Pharma Gmbh	Di-aryl acid derivatives as ppar receptor ligands
CA2371271A1 (fr)	1999-04-30	2000-11-09	Neurogen Corporation	Derives 9h-pyrimido[4,5-b]indoles: ligands specifiques de crf1
GB9911863D0 (en)	1999-05-21	1999-07-21	Knoll Ag	Therapeutic agents
CA2376919C (fr)	1999-06-18	2008-11-04	Merck & Co., Inc.	Derives d'arylthiazolidinedione et d'aryloxazolidinedione
DK1204654T3 (da)	1999-07-29	2003-11-17	Lilly Co Eli	Benzofurylpiperaziner og benzofurylhomopiperaziner: Serotonin agonister
US6324512B1 (en)	1999-08-26	2001-11-27	Matsushita Electric Industrial Co., Ltd.	System and method for allowing family members to access TV contents and program media recorder over telephone or internet
UA71994C2 (en) *	1999-08-31	2005-01-17	Kissei Pharmaceutical	Glucopyranosyloxypyrazole derivatives, a pharmaceutical composition containing these derivatives and intermediate compounds for the preparation thereof
PT1277736E (pt)	2000-04-28	2007-10-12	Asahi Kasei Pharma Corp	Novos compostos bicíclicos
JP2004507456A (ja)	2000-05-11	2004-03-11	ブリストル−マイヤーズ　スクイブ　カンパニー	成長ホルモン分泌促進薬として有用なテトラヒドロイソキノリン類縁体
AU2001264977B2 (en)	2000-05-30	2005-04-14	Merck & Co., Inc.	Melanocortin receptor agonists

2002
- 2002-07-11 DE DE10231370A patent/DE10231370B4/de not_active Expired - Fee Related
2003
- 2003-06-23 JO JOP/2003/0068A patent/JO2707B1/ar active
- 2003-06-27 KR KR10-2005-7000500A patent/KR20050021452A/ko not_active Ceased
- 2003-06-27 HR HR20050014A patent/HRP20050014A2/hr not_active Application Discontinuation
- 2003-06-27 DK DK03763662T patent/DK1523488T3/da active
- 2003-06-27 AT AT03763662T patent/ATE414095T1/de not_active IP Right Cessation
- 2003-06-27 PT PT03763662T patent/PT1523488E/pt unknown
- 2003-06-27 CN CNA2008100828971A patent/CN101240000A/zh active Pending
- 2003-06-27 AU AU2003246620A patent/AU2003246620B2/en not_active Ceased
- 2003-06-27 ES ES03763662T patent/ES2316818T3/es not_active Expired - Lifetime
- 2003-06-27 RU RU2005103602/04A patent/RU2317300C2/ru not_active IP Right Cessation
- 2003-06-27 DE DE50312984T patent/DE50312984D1/de not_active Expired - Lifetime
- 2003-06-27 JP JP2004520429A patent/JP4511927B2/ja not_active Expired - Fee Related
- 2003-06-27 CN CNB038165325A patent/CN100384863C/zh not_active Expired - Fee Related
- 2003-06-27 RS YUP-1150/04A patent/RS51002B/sr unknown
- 2003-06-27 AT AT08009226T patent/ATE477265T1/de active
- 2003-06-27 MX MXPA05000044A patent/MXPA05000044A/es active IP Right Grant
- 2003-06-27 EP EP03763662A patent/EP1523488B1/fr not_active Expired - Lifetime
- 2003-06-27 DE DE50312983T patent/DE50312983D1/de not_active Expired - Lifetime
- 2003-06-27 PL PL03372931A patent/PL372931A1/xx not_active Application Discontinuation
- 2003-06-27 AT AT08008232T patent/ATE477266T1/de active
- 2003-06-27 EP EP08008232A patent/EP1967523B1/fr not_active Expired - Lifetime
- 2003-06-27 EP EP08008079A patent/EP1964844B1/fr not_active Expired - Lifetime
- 2003-06-27 WO PCT/EP2003/006841 patent/WO2004007517A1/fr not_active Ceased
- 2003-06-27 CA CA2493391A patent/CA2493391C/fr not_active Expired - Fee Related
- 2003-06-27 ME MEP-607/08A patent/MEP60708A/xx unknown
- 2003-06-27 BR BR0312513-0A patent/BR0312513A/pt not_active IP Right Cessation
- 2003-06-27 UA UAA200501215A patent/UA78823C2/uk unknown
- 2003-06-27 AT AT08008079T patent/ATE479697T1/de active
- 2003-06-27 DE DE50313056T patent/DE50313056D1/de not_active Expired - Lifetime
- 2003-06-27 SI SI200331500T patent/SI1523488T1/sl unknown
- 2003-06-27 EP EP08009226A patent/EP1964845B1/fr not_active Expired - Lifetime
- 2003-06-27 OA OA1200500001A patent/OA12880A/en unknown
- 2003-06-27 DE DE50310783T patent/DE50310783D1/de not_active Expired - Lifetime
- 2003-07-08 AR AR20030102456A patent/AR040474A1/es unknown
- 2003-07-09 TW TW092118657A patent/TWI318981B/zh active
- 2003-07-09 PE PE2003000688A patent/PE20040655A1/es not_active Application Discontinuation
- 2003-07-10 HN HN2003000215A patent/HN2003000215A/es unknown
- 2003-07-10 PA PA20038577101A patent/PA8577101A1/es unknown
- 2003-07-10 MY MYPI20032596A patent/MY137039A/en unknown
- 2003-07-11 UY UY27891A patent/UY27891A1/es unknown
- 2003-07-11 US US10/616,945 patent/US7101856B2/en not_active Expired - Lifetime
2004
- 2004-12-02 ZA ZA200409779A patent/ZA200409779B/en unknown
- 2004-12-14 MA MA28004A patent/MA27366A1/fr unknown
- 2004-12-23 IL IL16605804A patent/IL166058A0/xx not_active IP Right Cessation
2005
- 2005-01-10 TN TNP2005000007A patent/TNSN05007A1/en unknown
- 2005-01-11 EC EC2005005531A patent/ECSP055531A/es unknown
- 2005-02-07 NO NO20050649A patent/NO20050649L/no unknown
- 2005-03-07 CR CR7718A patent/CR7718A/es not_active Application Discontinuation
2006
- 2006-08-14 US US11/464,338 patent/US7666848B2/en not_active Expired - Fee Related
2008
- 2008-06-03 IL IL191926A patent/IL191926A0/en unknown
2009
- 2009-02-05 CY CY20091100138T patent/CY1108754T1/el unknown

Also Published As

Publication number	Publication date
EP1964845B1 (fr)	2010-08-11
DE50312983D1 (de)	2010-09-23
US20040138143A1 (en)	2004-07-15
PT1523488E (pt)	2009-01-30
UA78823C2 (en)	2007-04-25
ATE479697T1 (de)	2010-09-15
EP1967523A1 (fr)	2008-09-10
HK1080482A1 (en)	2006-04-28
EP1523488B1 (fr)	2008-11-12
ATE477266T1 (de)	2010-08-15
DE50312984D1 (de)	2010-09-23
EP1964845A1 (fr)	2008-09-03
PL372931A1 (en)	2005-08-08
ES2316818T3 (es)	2009-04-16
US7666848B2 (en)	2010-02-23
ZA200409779B (en)	2006-06-28
MA27366A1 (fr)	2005-06-01
IL191926A0 (en)	2008-12-29
PA8577101A1 (es)	2004-02-07
US7101856B2 (en)	2006-09-05
KR20050021452A (ko)	2005-03-07
DE50310783D1 (de)	2008-12-24
CR7718A (es)	2006-05-11
SI1523488T1 (sl)	2009-04-30
TNSN05007A1 (en)	2007-05-14
ECSP055531A (es)	2005-03-10
JP4511927B2 (ja)	2010-07-28
MXPA05000044A (es)	2005-04-08
ATE414095T1 (de)	2008-11-15
MY137039A (en)	2008-12-31
OA12880A (en)	2006-09-15
BR0312513A (pt)	2005-04-12
DE50313056D1 (de)	2010-10-14
CA2493391A1 (fr)	2004-01-22
UY27891A1 (es)	2003-12-31
US20060293252A1 (en)	2006-12-28
EP1964844B1 (fr)	2010-09-01
EP1964844A1 (fr)	2008-09-03
AU2003246620B2 (en)	2009-03-19
IL166058A0 (en)	2006-01-15
TW200410979A (en)	2004-07-01
ATE477265T1 (de)	2010-08-15
CA2493391C (fr)	2010-06-15
RS51002B (sr)	2010-10-31
TWI318981B (en)	2010-01-01
MEP60708A (en)	2011-05-10
DK1523488T3 (da)	2009-03-16
WO2004007517A1 (fr)	2004-01-22
AR040474A1 (es)	2005-04-06
JO2707B1 (ar)	2014-03-15
RS115004A (sr)	2007-02-05
AU2003246620A1 (en)	2004-02-02
DE10231370A1 (de)	2004-02-05
JP2005536497A (ja)	2005-12-02
CN100384863C (zh)	2008-04-30
HRP20050014A2 (hr)	2006-04-30
EP1523488A1 (fr)	2005-04-20
CN1668628A (zh)	2005-09-14
EP1967523B1 (fr)	2010-08-11
RU2317300C2 (ru)	2008-02-20
RU2005103602A (ru)	2005-07-20
HN2003000215A (es)	2004-07-27
CY1108754T1 (el)	2014-04-09
DE10231370B4 (de)	2006-04-06
PE20040655A1 (es)	2004-11-15
CN101240000A (zh)	2008-08-13

Publication	Publication Date	Title
NO20070176L (no)	2007-03-09	Nye fluorglykosidderivater av pyrazoler, medikamenter inneholdende disse forbindelsene og anvendelse derav
NO20044882L (no)	2004-11-09	Acyl-4-karboksylfenylurinstoffderivater, deres fremstilling og anvendelse
NO20091893L (no)	2009-07-09	Nye 1,4-benzotiepin-1,1-dioksidderivater som er substituert med benzylgrupper, fremgangsmater for fremstilling av medisiner inneholdende forbindelsene og anvendelse derav.
NO20053201L (no)	2005-08-04	Nye heterocykliske fluorglukosidderivater, legemidler inneholdende disse forbindelser og deres anvendelse.
NO20071593L (no)	2007-05-22	Pyrimidinderivater
NO20064201L (no)	2006-12-13	Glukopyranosylsubstituerte benzolderivater, medikamenter inneholdende slike forbindelser, deres anvendelse og fremstilling
JO2707B1 (ar)	2014-03-15	مشتقات ثيوفين جليكوسايد جديدة, طرق تحضيرها, والادوية المحتوية على هذه المركبات واستخدامها
NO20076460L (no)	2008-02-19	Nye fluorenderivater, sammensetninger inneholdende nevnte derivater og anvendelse derav
NO20056132L (no)	2006-01-26	Krystallinsk form av beta2 adrenergisk receptoragonist
NO20066055L (no)	2007-01-24	Pyridinderivater
BRPI0508098A (pt)	2007-07-17	compostos, composições farmacêuticas e métodos para uso no tratamento de distúrbios metabólicos
SE0202463D0 (sv)	2002-08-14	Novel compounds
BRPI0514537B8 (pt)	2021-05-25	compostos de aminoeteroarila substituídos com pirazol e composição farmacêutica que os compreende
NO20084129L (no)	2008-10-29	Pyridin(3,4-B)Pyrazinoner
MX2009011964A (es)	2009-12-01	Derivados heterociclicos pirrolo-nitrogenosos, su preparacion y uso farmaceutico.
NO20050828L (no)	2005-04-05	lndol-3-svovelderivater
SG151254A1 (en)	2009-04-30	Substituted morpholine and thiomorpholine derivatives
NO20055219L (no)	2006-01-04	Nye forbindelser
NO20076695L (no)	2008-02-28	Nye MCHR1-antagonister og deres anvendelse for behandling av MCHR1-medierte tilstander og forstyrrelser
DK1506185T3 (da)	2006-10-02	Forbindelser og deres anvendelse som 5-HT-inhibitorer
SG171681A1 (en)	2011-06-29	Crystalline forms and processes for the preparation of phenyl-pyrazoles useful as modulators of the 5-ht2a serotonin receptor
SE0403171D0 (sv)	2004-12-23	New compounds
NO20072005L (no)	2007-06-15	Nye heterocykliske amider
NO20083325L (no)	2008-09-18	Karbonater av antibiotiske fenicolforbindelser
SE0301701D0 (sv)	2003-06-10	Benzimidazole derivatives, compositions containing them, preparation thereof and uses thereof