NO20050835L - Varmsmelte TTS for administrasjon av rotigotin - Google Patents
Varmsmelte TTS for administrasjon av rotigotinInfo
- Publication number
- NO20050835L NO20050835L NO20050835A NO20050835A NO20050835L NO 20050835 L NO20050835 L NO 20050835L NO 20050835 A NO20050835 A NO 20050835A NO 20050835 A NO20050835 A NO 20050835A NO 20050835 L NO20050835 L NO 20050835L
- Authority
- NO
- Norway
- Prior art keywords
- rotigotine
- hot melt
- administration
- adhesive layer
- melt tts
- Prior art date
Links
- KFQYTPMOWPVWEJ-INIZCTEOSA-N rotigotine Chemical compound CCCN([C@@H]1CC2=CC=CC(O)=C2CC1)CCC1=CC=CS1 KFQYTPMOWPVWEJ-INIZCTEOSA-N 0.000 title abstract 3
- 229960003179 rotigotine Drugs 0.000 title abstract 3
- 239000012943 hotmelt Substances 0.000 title abstract 2
- 239000012790 adhesive layer Substances 0.000 abstract 3
- 239000004821 Contact adhesive Substances 0.000 abstract 1
- 238000002844 melting Methods 0.000 abstract 1
- 230000008018 melting Effects 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
- A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
- A61K9/7069—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained otherwise than by reactions only involving carbon to carbon unsaturated bonds, e.g. polysiloxane, polyesters, polyurethane, polyethylene oxide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
- A61K31/381—Heterocyclic compounds having sulfur as a ring hetero atom having five-membered rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Dermatology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Psychology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Adhesives Or Adhesive Processes (AREA)
- Medicines Containing Plant Substances (AREA)
- External Artificial Organs (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10234673A DE10234673B4 (de) | 2002-07-30 | 2002-07-30 | Heißschmelz-TTS zur Verabreichung von Rotigotin und Verfahren zu seiner Herstellung sowie Verwendung von Rotigotin bei der Herstellung eines TTS im Heißschmelzverfahren |
| PCT/EP2003/008348 WO2004012721A2 (fr) | 2002-07-30 | 2003-07-29 | Systeme therapeutique transdermique (tts) realise par thermofusion pour administrer de la rotigotine |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NO20050835L true NO20050835L (no) | 2005-02-16 |
Family
ID=30469194
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20050835A NO20050835L (no) | 2002-07-30 | 2005-02-16 | Varmsmelte TTS for administrasjon av rotigotin |
Country Status (21)
| Country | Link |
|---|---|
| US (1) | US9186335B2 (fr) |
| EP (2) | EP1669063A1 (fr) |
| JP (1) | JP4514608B2 (fr) |
| KR (1) | KR101041512B1 (fr) |
| CN (1) | CN100574755C (fr) |
| AT (1) | ATE324875T1 (fr) |
| AU (1) | AU2003269859B2 (fr) |
| BR (1) | BR0311437A (fr) |
| CA (1) | CA2494361C (fr) |
| CY (1) | CY1105138T1 (fr) |
| DE (2) | DE10234673B4 (fr) |
| DK (1) | DK1492517T3 (fr) |
| ES (1) | ES2263999T3 (fr) |
| IL (1) | IL166070A0 (fr) |
| MX (1) | MXPA04012150A (fr) |
| NO (1) | NO20050835L (fr) |
| PL (1) | PL221308B1 (fr) |
| PT (1) | PT1492517E (fr) |
| RU (1) | RU2304434C2 (fr) |
| WO (1) | WO2004012721A2 (fr) |
| ZA (1) | ZA200500457B (fr) |
Families Citing this family (56)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19814084B4 (de) * | 1998-03-30 | 2005-12-22 | Lts Lohmann Therapie-Systeme Ag | D2-Agonist enthaltendes transdermales therapeutisches System zur Behandlung des Parkinson-Syndroms und Verfahren zu seiner Herstellung |
| DE10041478A1 (de) | 2000-08-24 | 2002-03-14 | Sanol Arznei Schwarz Gmbh | Neue pharmazeutische Zusammensetzung |
| DE10041479A1 (de) * | 2000-08-24 | 2002-03-14 | Sanol Arznei Schwarz Gmbh | Neue pharmazeutische Zusammensetzung zur Verabreichung von N-0923 |
| US20040048779A1 (en) * | 2002-05-06 | 2004-03-11 | Erwin Schollmayer | Use of rotigotine for treating the restless leg syndrome |
| US8246979B2 (en) | 2002-07-30 | 2012-08-21 | Ucb Pharma Gmbh | Transdermal delivery system for the administration of rotigotine |
| US8211462B2 (en) * | 2002-07-30 | 2012-07-03 | Ucb Pharma Gmbh | Hot-melt TTS for administering rotigotine |
| DE10234673B4 (de) | 2002-07-30 | 2007-08-16 | Schwarz Pharma Ag | Heißschmelz-TTS zur Verabreichung von Rotigotin und Verfahren zu seiner Herstellung sowie Verwendung von Rotigotin bei der Herstellung eines TTS im Heißschmelzverfahren |
| US8246980B2 (en) * | 2002-07-30 | 2012-08-21 | Ucb Pharma Gmbh | Transdermal delivery system |
| DE10261696A1 (de) * | 2002-12-30 | 2004-07-15 | Schwarz Pharma Ag | Vorrichtung zur transdermalen Verabreichung von Rotigotin-Base |
| DE10334188B4 (de) * | 2003-07-26 | 2007-07-05 | Schwarz Pharma Ag | Verwendung von Rotigotin zur Behandlung von Depressionen |
| DE10359528A1 (de) | 2003-12-18 | 2005-07-28 | Schwarz Pharma Ag | (S)-2-N-Propylamino-5-hydroxytetralin als D3-agonistisches Therapeutikum |
| DE10361258A1 (de) * | 2003-12-24 | 2005-07-28 | Schwarz Pharma Ag | Verwendung von substituierten 2-Aminotetralinen zur vorbeugenden Behandlung von Morbus Parkinson |
| US20050197385A1 (en) * | 2004-02-20 | 2005-09-08 | Schwarz Pharma Ag | Use of rotigotine for treatment or prevention of dopaminergic neuron loss |
| DE102004014841B4 (de) | 2004-03-24 | 2006-07-06 | Schwarz Pharma Ag | Verwendung von Rotigotin zur Behandlung und Prävention des Parkinson-Plus-Syndroms |
| DE602005020393D1 (de) * | 2004-06-01 | 2010-05-20 | Hisamitsu Pharmaceutical Co | Adhäsive Pflaster |
| JP4986411B2 (ja) * | 2004-06-01 | 2012-07-25 | 久光製薬株式会社 | 貼付剤 |
| JP2008514376A (ja) * | 2004-09-29 | 2008-05-08 | シュウォーツ ファーマ インコーポレイテッド | パーキンソン病のための経皮治療システム |
| DE102006026578B4 (de) | 2006-06-08 | 2009-01-08 | Lts Lohmann Therapie-Systeme Ag | Wirkstoffpartikelhaltiges Transdermales Therapeutisches System mit erhöhtem Wirkstofffluss und Verfahren zu seiner Herstellung sowie Verwendung |
| TWI392670B (zh) * | 2006-06-22 | 2013-04-11 | Ucb Pharma Gmbh | 經取代的2-胺基萘滿之於製造用於預防、減緩及/或治療各種類型疼痛之藥物上的用途 |
| DE102006059462A1 (de) * | 2006-12-14 | 2008-06-19 | Henkel Kgaa | Hot melt für Mikrowellen-Erwärmung |
| US20080226698A1 (en) * | 2007-03-16 | 2008-09-18 | Mylan Technologies, Inc. | Amorphous drug transdermal systems, manufacturing methods, and stabilization |
| EP1987815A1 (fr) * | 2007-05-04 | 2008-11-05 | Schwarz Pharma Ag | Compositions pharmaceutiques à base d'agonistes dopaminergiques administrables par voie oro-naso-pharyngale pour la prévention et/ou le traitement de membres sans repos |
| US8344165B2 (en) | 2007-05-30 | 2013-01-01 | Chemagis Ltd. | Crystalline rotigotine base and preparation process therefor |
| CN101147739B (zh) * | 2007-07-06 | 2010-12-08 | 北京康倍得医药技术开发有限公司 | 含罗替戈汀的组合物及其制药用途以及含该组合物的透皮贴剂 |
| NZ584363A (en) * | 2007-11-28 | 2012-11-30 | Ucb Pharma Gmbh | Drug formulations of Rotigotine which comprise the thermodynamically stable polymorphic form 2 |
| AU2009302853B2 (en) * | 2008-10-06 | 2014-09-11 | Mylan Technologies, Inc. | Amorphous rotigotine transdermal system |
| DE102008060203A1 (de) | 2008-12-07 | 2010-06-10 | Dietrich Wilhelm Schacht | Wirkstoffstabilisierende flächenförmige Vorrichtung |
| EP2281559A1 (fr) | 2009-06-26 | 2011-02-09 | UCB Pharma GmbH | Composition pharmaceutique contenante un sel de rotigotine (sel d'acid ou Na), notament pour iontophorèse |
| DE102009052972A1 (de) * | 2009-11-12 | 2011-09-15 | Lts Lohmann Therapie-Systeme Ag | Verfahren zur Verhinderung der Kristallisation von Arzneistoffen in einem Polymerfilm |
| LT3257504T (lt) * | 2009-12-22 | 2024-08-26 | UCB Biopharma SRL | Polivinilpirolidonas, skirtas nekristalinės formos kietos rotigotino dispersijos stabilizavimui |
| MX339408B (es) * | 2010-03-09 | 2016-05-24 | Alkermes Pharma Ireland Ltd | Composiciones farmaceuticas entericas resistentes al alcohol. |
| KR101481643B1 (ko) * | 2010-11-25 | 2015-01-12 | 산동 루예 파마슈티칼 컴파니 리미티드 | 로티고틴, 이의 유도체 또는 로티고틴 또는 이의 유도체의 약제학적으로 허용가능한 염의 조성물 |
| WO2012084969A1 (fr) | 2010-12-22 | 2012-06-28 | Hexal Ag | Composition adhésive contenant de la rotigotine et système thérapeutique transdermique comprenant la composition adhésive |
| EP2559435A1 (fr) | 2011-08-19 | 2013-02-20 | UCB Pharma GmbH | Rotigotine pour le traitement des négligences spatiales unilatérales, accidents vasculaires cérébraux et troubles suivant un accident vasculaire |
| JP5856424B2 (ja) * | 2011-10-05 | 2016-02-09 | 祐徳薬品工業株式会社 | ロチゴチン含有経皮吸収型貼付剤 |
| DE102012013439A1 (de) | 2012-07-03 | 2014-01-23 | Alfred E. Tiefenbacher (Gmbh & Co. Kg) | Transdermales therapeutisches System umfassend Rotigotin und Kristallisationsinhibitor |
| DE102012013421A1 (de) | 2012-07-03 | 2014-01-09 | Alfred E. Tiefenbacher (Gmbh & Co. Kg) | Transdermales therapeutisches System (TTS) mit Rotigotin |
| DE102011119043A1 (de) | 2011-11-22 | 2013-05-23 | Alfred E. Tiefenbacher (Gmbh & Co. Kg) | Transdermales therapeutisches System (TDS) mit Rotigotin |
| WO2013075823A1 (fr) | 2011-11-22 | 2013-05-30 | Alfred E. Tiefenbacher (Gmbh & Co. Kg) | Système thérapeutique transdermique comprenant de la rotigotine et un inhibiteur de cristallisation |
| DE102011090178A1 (de) * | 2011-12-30 | 2013-07-04 | Lts Lohmann Therapie-Systeme Ag | Transdermales therapeutisches System mit geringer Neigung zur Spontankristallisation |
| MX2015000049A (es) * | 2012-07-05 | 2015-04-08 | Sk Chemicals Co Ltd | Preparacion absorbible transdermicamente que contiene rotigotina. |
| EP2870963A4 (fr) * | 2012-07-06 | 2016-03-09 | Sk Chemicals Co Ltd | Préparation contenant de la rotigotine destinée à être absorbée par voie percutanée |
| TW201431570A (zh) * | 2012-11-22 | 2014-08-16 | Ucb Pharma Gmbh | 用於經皮投服羅替戈汀(Rotigotine)之多天式貼片 |
| KR101686987B1 (ko) * | 2013-05-30 | 2016-12-15 | 에스케이케미칼주식회사 | 로티고틴과 지방산 및 스티렌 점착제를 함유한 경피치료시스템 |
| US20160199316A1 (en) * | 2013-06-14 | 2016-07-14 | Tesa Labtec Gmbh | Three-layer transdermal therapy system (tts) |
| WO2014198422A1 (fr) * | 2013-06-14 | 2014-12-18 | Tesa Labtec Gmbh | Système thérapeutique transdermique (tts) doté de rotigotine |
| AU2014281317A1 (en) * | 2013-06-20 | 2016-02-04 | Mylan Technologies, Inc. | Storage stable transdermal patch of rotigotine |
| JP6726096B2 (ja) | 2013-07-03 | 2020-07-22 | エルテーエス ローマン テラピー−システメ アーゲー | 電子部品を有する経皮治療システム |
| CN106456566B (zh) | 2014-05-20 | 2020-06-16 | Lts勒曼治疗系统股份公司 | 含罗替戈汀的经皮递送系统 |
| US11752110B2 (en) | 2014-05-20 | 2023-09-12 | Lts Lohmann Therapie-Systeme Ag | Transdermal delivery system including an interface mediator |
| CA2948219C (fr) | 2014-05-20 | 2023-04-04 | Lts Lohmann Therapie-Systeme Ag | Methode de regulation de liberation d'agent actif dans un systeme d'administration transdermique |
| KR102364378B1 (ko) * | 2014-05-21 | 2022-02-16 | 에스케이케미칼 주식회사 | 안정성을 향상시킨 로티고틴 함유 경피흡수제제 |
| WO2019234662A1 (fr) * | 2018-06-07 | 2019-12-12 | Nal Pharmaceutical Group Limited | Système d'administration transdermique de médicament, contenant de la rotigotine |
| KR102731700B1 (ko) * | 2018-10-24 | 2024-11-15 | 에스케이케미칼 주식회사 | 비결정 로티고틴 함유 조성물 및 이의 제조 방법 |
| KR102260202B1 (ko) * | 2019-10-30 | 2021-06-03 | 에바바이오 주식회사 | 로티고틴 공융 혼합물 및 이의 용도 |
| ES2966170T3 (es) | 2020-01-24 | 2024-04-18 | Luye Pharma Switzerland Ag | Sistema terapéutico transdérmico que comprende rotigotina y al menos un adhesivo de silicona no resistente a las aminas |
Family Cites Families (116)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US36754A (en) * | 1862-10-21 | Improvement in watch-chain guards or keys | ||
| US4144317A (en) | 1975-05-30 | 1979-03-13 | Alza Corporation | Device consisting of copolymer having acetoxy groups for delivering drugs |
| US5177112A (en) | 1983-01-03 | 1993-01-05 | Whitby Research, Inc. | Substituted 2-aminotetralins |
| US4655767A (en) | 1984-10-29 | 1987-04-07 | Dow Corning Corporation | Transdermal drug delivery devices with amine-resistant silicone adhesives |
| US4880633A (en) | 1986-03-12 | 1989-11-14 | Merck & Co., Inc. | Transdermal drug delivery system |
| US4863970A (en) | 1986-11-14 | 1989-09-05 | Theratech, Inc. | Penetration enhancement with binary system of oleic acid, oleins, and oleyl alcohol with lower alcohols |
| US5273757A (en) | 1987-09-01 | 1993-12-28 | Lts Lohmann Therapie-Systeme Gmbh & Co. Kg | Apparatus for the delivery of substances, processes for the production thereof and use thereof |
| DE3743945A1 (de) * | 1987-09-01 | 1989-03-09 | Lohmann Gmbh & Co Kg | Vorrichtung zur abgabe von stoffen, verfahren zu ihrer herstellung sowie ihre verwendung |
| US4915950A (en) | 1988-02-12 | 1990-04-10 | Cygnus Research Corporation | Printed transdermal drug delivery device |
| US5656286A (en) | 1988-03-04 | 1997-08-12 | Noven Pharmaceuticals, Inc. | Solubility parameter based drug delivery system and method for altering drug saturation concentration |
| DE3827561C1 (fr) | 1988-08-13 | 1989-12-28 | Lts Lohmann Therapie-Systeme Gmbh & Co Kg, 5450 Neuwied, De | |
| US4865920A (en) | 1988-09-20 | 1989-09-12 | Dow Corning Corporation | Hot-melt pressure sensitive adhesive article and method of making |
| US4973468A (en) | 1989-03-22 | 1990-11-27 | Cygnus Research Corporation | Skin permeation enhancer compositions |
| FR2648131B1 (fr) | 1989-06-13 | 1991-10-18 | Oreal | Nouveaux derives de tetrahydro -5,6,7,8 naphtalenol-1, leur procede de preparation et leur utilisation en tant qu'agents antioxydants dans des compositions cosmetiques et pharmaceutiques les contenant |
| US5252335A (en) | 1989-07-12 | 1993-10-12 | Cygnus Therapeutic Systems | Transdermal administration of lisuride |
| US5091186A (en) | 1989-08-15 | 1992-02-25 | Cygnus Therapeutic Systems | Biphasic transdermal drug delivery device |
| US5124157A (en) | 1989-08-18 | 1992-06-23 | Cygnus Therapeutic Systems | Method and device for administering dexmedetomidine transdermally |
| US5252334A (en) | 1989-09-08 | 1993-10-12 | Cygnus Therapeutic Systems | Solid matrix system for transdermal drug delivery |
| US5271940A (en) | 1989-09-14 | 1993-12-21 | Cygnus Therapeutic Systems | Transdermal delivery device having delayed onset |
| DE3933460A1 (de) | 1989-10-06 | 1991-04-18 | Lohmann Therapie Syst Lts | Oestrogenhaltiges wirkstoffpflaster |
| US5147916A (en) | 1990-02-21 | 1992-09-15 | Dow Corning Corporation | Hot-melt silicone pressure sensitive adhesive composition and related methods and articles |
| US5246997A (en) * | 1990-02-21 | 1993-09-21 | Dow Corning Corporation | Method of making a hot-melt silicone pressure sensitive adhesive-coated substrate |
| US5069909A (en) | 1990-06-20 | 1991-12-03 | Cygnus Therapeutic Systems | Transdermal administration of buprenorphine |
| US5328696A (en) * | 1991-07-22 | 1994-07-12 | Dow Corning Corporation | Devices using silicone pressure sensitive adhesives containing organic wax |
| US5300299A (en) * | 1991-07-22 | 1994-04-05 | Dow Corning Corporation | Silicone pressure sensitive adhesive containing alkylmethylsiloxane wax and related methods and devices |
| US5273755A (en) | 1991-08-23 | 1993-12-28 | Cygnus Therapeutic Systems | Transdermal drug delivery device using a polymer-filled microporous membrane to achieve delayed onset |
| US5234690A (en) | 1991-08-23 | 1993-08-10 | Cygnus Therapeutic Systems | Transdermal drug delivery device using an unfilled microporous membrane to achieve delayed onset |
| US5273756A (en) | 1991-08-23 | 1993-12-28 | Cygnus Therapeutic Systems | Transdermal drug delivery device using a membrane-protected microporous membrane to achieve delayed onset |
| AU2514292A (en) | 1991-08-27 | 1993-03-16 | Cygnus Therapeutic Systems | Transdermal formulations for administering prazosin |
| US5225198A (en) | 1991-08-27 | 1993-07-06 | Cygnus Therapeutic Systems | Transdermal administration of short or intermediate half-life benzodiazepines |
| JPH05208907A (ja) * | 1991-09-17 | 1993-08-20 | Sekisui Chem Co Ltd | 消炎鎮痛貼付剤 |
| AU2782592A (en) | 1991-10-15 | 1993-05-21 | Cygnus Therapeutic Systems | Thermal enhancement of transdermal drug administration |
| WO1993014727A1 (fr) | 1992-01-31 | 1993-08-05 | Cygnus Therapeutic Systems | Administration transcutanee de buprenorphine sous forme de complexes de paires d'ion |
| GB9202915D0 (en) | 1992-02-12 | 1992-03-25 | Wellcome Found | Chemical compounds |
| DE4224325C1 (de) | 1992-07-23 | 1994-02-10 | Sanol Arznei Schwarz Gmbh | Wirkstoffpflaster für niedrigschmelzende und/oder flüchtige Wirkstoffe und Verfahren zu seiner Herstellung |
| CA2142871A1 (fr) | 1992-08-25 | 1994-03-03 | Jesus Miranda | Dispositif imprime de liberation transdermique des medicaments |
| US5308625A (en) | 1992-09-02 | 1994-05-03 | Cygnus Therapeutic Systems | Enhancement of transdermal drug delivery using monoalkyl phosphates and other absorption promoters |
| US5989586A (en) | 1992-10-05 | 1999-11-23 | Cygnus, Inc. | Two-phase matrix for sustained release drug delivery device |
| DE4301781C2 (de) * | 1993-01-23 | 1995-07-20 | Lohmann Therapie Syst Lts | Nitroglycerinhaltiges Pflaster, Verfahren zu seiner Herstellung und Verwendung |
| AU7172794A (en) | 1993-06-24 | 1995-01-17 | Cygnus Therapeutic Systems | Transdermal delivery system package |
| WO1995001767A1 (fr) | 1993-07-08 | 1995-01-19 | Cygnus Therapeutic Systems | Systeme d'apports transdermique par matrice monolithe |
| US5382596A (en) | 1993-08-05 | 1995-01-17 | Whitby Research, Inc. | Substituted 2-aminotetralins |
| US5554381A (en) | 1993-08-09 | 1996-09-10 | Cygnus, Inc. | Low flux matrix system for delivering potent drugs transdermally |
| AU7566994A (en) | 1993-08-16 | 1995-03-14 | Cygnus Therapeutic Systems | Contact adhesive extends wear time on skin |
| AU7517794A (en) | 1993-08-16 | 1995-03-14 | Cygnus Therapeutic Systems | Transdermal delivery system using a combination of permeation enhancers |
| US5482988A (en) | 1994-01-14 | 1996-01-09 | Dow Corning Corporation | Hot-melt silicone pressure sensitive adhesive with siloxylated polyether waxes as additives |
| CN1099663C (zh) | 1994-03-11 | 2003-01-22 | 皇家菲利浦电子有限公司 | 准周期信号的传输系统 |
| DE69519023T2 (de) | 1994-06-24 | 2001-06-13 | Cygnus, Inc. | Einrichtung zur iontophoretischen probennahme |
| US5771890A (en) | 1994-06-24 | 1998-06-30 | Cygnus, Inc. | Device and method for sampling of substances using alternating polarity |
| US6024974A (en) | 1995-01-06 | 2000-02-15 | Noven Pharmaceuticals, Inc. | Composition and methods for transdermal delivery of acid labile drugs |
| WO1996022083A1 (fr) | 1995-01-19 | 1996-07-25 | Cygnus, Inc. | Adhesifs a base de polyisobutylene, qui contiennent un agent collant a temperature de transition vitreuse elevee pour dispositifs transcutanes |
| AU4761196A (en) | 1995-01-19 | 1996-08-07 | Cygnus, Inc. | Polymer adhesive formulation containing sorbent particles |
| US5601839A (en) | 1995-04-26 | 1997-02-11 | Theratech, Inc. | Triacetin as a penetration enhancer for transdermal delivery of a basic drug |
| GB9511366D0 (en) | 1995-06-06 | 1995-08-02 | Smithkline Beecham Plc | Novel formulations |
| CN1188189C (zh) | 1995-06-07 | 2005-02-09 | 奥瑟-麦内尔制药公司 | 基质层含有17-脱乙酰基诺孕酯的经皮贴片及基质的用途 |
| US5785991A (en) | 1995-06-07 | 1998-07-28 | Alza Corporation | Skin permeation enhancer compositions comprising glycerol monolaurate and lauryl acetate |
| US6316022B1 (en) | 1995-06-07 | 2001-11-13 | Noven Pharmaceuticals, Inc. | Transdermal compositions containing low molecular weight drugs which are liquid at room temperatures |
| WO1996040087A2 (fr) | 1995-06-07 | 1996-12-19 | Cygnus, Inc. | Composition acrylique adhesive sensible a la pression reticulee avec de l'acetylacetonate d'aluminium et contenant un medicament qui renferme un groupe hydroxy aromatique reactif |
| US5559165A (en) | 1995-08-08 | 1996-09-24 | National Starch And Chemical Investment Holding Corporation | Hot melt adhesives for bonding to sensitive areas of the human body |
| US5906830A (en) | 1995-09-08 | 1999-05-25 | Cygnus, Inc. | Supersaturated transdermal drug delivery systems, and methods for manufacturing the same |
| AU7238896A (en) | 1995-09-14 | 1997-04-01 | Cygnus, Inc. | High capacity, superabsorbent drug reservoirs for use in transdermal drug delivery systems |
| US5902603A (en) | 1995-09-14 | 1999-05-11 | Cygnus, Inc. | Polyurethane hydrogel drug reservoirs for use in transdermal drug delivery systems, and associated methods of manufacture and use |
| US5891461A (en) | 1995-09-14 | 1999-04-06 | Cygnus, Inc. | Transdermal administration of olanzapine |
| US6063398A (en) | 1995-09-20 | 2000-05-16 | L'oreal | Cosmetic or dermopharmaceutical patch containing, in an anhydrous polymeric matrix, at least one active compound which is, in particular, unstable in oxidizing mediums, and at least one water-absorbing agent |
| US5807570A (en) | 1995-09-29 | 1998-09-15 | Cygnus, Inc. | Transdermal administration of ropinirole and analogs thereof |
| US5733571A (en) | 1995-12-08 | 1998-03-31 | Euro-Celtique, S.A. | Transdermal patch for comparative evaluations |
| AUPN814496A0 (en) | 1996-02-19 | 1996-03-14 | Monash University | Dermal penetration enhancer |
| US5879701A (en) | 1997-02-28 | 1999-03-09 | Cygnus, Inc. | Transdermal delivery of basic drugs using nonpolar adhesive systems and acidic solubilizing agents |
| US5843472A (en) | 1997-02-28 | 1998-12-01 | Cygnus, Inc. | Transdermal drug delivery sytem for the administration of tamsulosin, and related compositions and methods of use |
| DE19814084B4 (de) * | 1998-03-30 | 2005-12-22 | Lts Lohmann Therapie-Systeme Ag | D2-Agonist enthaltendes transdermales therapeutisches System zur Behandlung des Parkinson-Syndroms und Verfahren zu seiner Herstellung |
| DE19814083C2 (de) * | 1998-03-30 | 2002-02-07 | Lohmann Therapie Syst Lts | Verfahren zur Herstellung von transdermalen therapeutischen Systemen unter Verwendung von basischen Alkalimetallsalzen zur Umwandlung von Wirkstoffsalzen in die freien Basen |
| ATE220936T1 (de) | 1998-05-13 | 2002-08-15 | Cygnus Therapeutic Systems | Sammelvorrichtungen für transdermale probennahmesysteme |
| DE19821788C1 (de) | 1998-05-15 | 1999-12-02 | Sanol Arznei Schwarz Gmbh | Transdermales Therapeutisches System (TTS) Pergolid enthaltend |
| DE19828273B4 (de) | 1998-06-25 | 2005-02-24 | Lts Lohmann Therapie-Systeme Ag | Transdermales therapeutisches System, enthaltend Hormone und Kristallisationsinhibitoren |
| CA2344254A1 (fr) | 1998-09-17 | 2000-03-23 | Cygnus, Inc. | Presse concue pour un ensemble detecteur a gel |
| EP1169025B1 (fr) | 1999-04-01 | 2005-08-24 | Alza Corporation | Dispositifs d'administration transdermale de medicaments comprenant un reservoir de medicament en polyurethane |
| FR2792529B1 (fr) | 1999-04-26 | 2001-09-28 | Sod Conseils Rech Applic | Nouvelles compositions pharmaceutiques comprenant des derives de 2-isoxazole-8-aminotetralines |
| WO2000074661A2 (fr) | 1999-06-05 | 2000-12-14 | Noven Pharmaceuticals, Inc. | Amelioration de la solubilite de medicaments dans des systemes d'administration transdermique de medicaments et procedes d'utilisation |
| US6218421B1 (en) | 1999-07-01 | 2001-04-17 | Smithkline Beecham P.L.C. | Method of promoting smoking cessation |
| DE19958554C2 (de) * | 1999-07-02 | 2002-06-13 | Lohmann Therapie Syst Lts | Mikroreservoirsystem auf Basis von Polysiloxanen und ambiphilen Lösemitteln und ihre Herstellung |
| DE19940238A1 (de) | 1999-08-25 | 2001-03-01 | Lohmann Therapie Syst Lts | Wirkstoffhaltiges therapeutisches System zur Applikation auf der Haut mit mindestens zwei polymerhaltigen Schichten |
| DE60008136T2 (de) | 1999-11-23 | 2004-09-09 | Aderis Pharmaceuticals, Inc. | Verbessertes verfahren zur herstellung von n-substituierte aminotetraline |
| MXPA02005292A (es) | 1999-11-29 | 2002-12-11 | Lohmann Therapie Syst Lts | Sistemas terapeuticos transdermicos que tienen estabilidad mejorada y su produccion. |
| US20020110585A1 (en) | 1999-11-30 | 2002-08-15 | Godbey Kristin J. | Patch therapeutic agent delivery device having texturized backing |
| DE10041479A1 (de) | 2000-08-24 | 2002-03-14 | Sanol Arznei Schwarz Gmbh | Neue pharmazeutische Zusammensetzung zur Verabreichung von N-0923 |
| DE10041478A1 (de) | 2000-08-24 | 2002-03-14 | Sanol Arznei Schwarz Gmbh | Neue pharmazeutische Zusammensetzung |
| US20020119187A1 (en) | 2000-09-29 | 2002-08-29 | Cantor Adam S. | Composition for the transdermal delivery of fentanyl |
| DE10060550C1 (de) | 2000-12-06 | 2002-04-18 | Lohmann Therapie Syst Lts | Transdermales therapeutisches System mit dem Wirkstoff Oxybutynin und Verfahren zur Herstellung Oxybutynin enthaltender Wirkstoffschichten |
| ATE246919T1 (de) * | 2001-05-08 | 2003-08-15 | Sanol Arznei Schwarz Gmbh | Verbessertes transdermales therapeutisches system zur behandlung von morbus parkinson |
| US20030026830A1 (en) | 2001-05-08 | 2003-02-06 | Thomas Lauterback | Transdermal therapeutic system for parkinson's disease inducing high plasma levels of rotigotine |
| US20030027793A1 (en) | 2001-05-08 | 2003-02-06 | Thomas Lauterback | Transdermal treatment of parkinson's disease |
| FR2829028B1 (fr) | 2001-08-29 | 2004-12-17 | Aventis Pharma Sa | Association d'un antagoniste du recepteur cb1 et d'un produit qui active la neurotransmission dopaminergique dans le cerveau, les compositions pharmaceutiques les contenant et leur utilisation pour le traitement de la maladie de |
| US20060263419A1 (en) | 2002-03-12 | 2006-11-23 | Hans-Michael Wolff | Transdermal therapeutic system for Parkinson's Disease |
| US20040034083A1 (en) | 2002-04-18 | 2004-02-19 | Stephenson Diane T. | Combination therapy for the treatment of Parkinson's disease with cyclooxygenase-2 (COX2) inhibitor(s) |
| US20040048779A1 (en) | 2002-05-06 | 2004-03-11 | Erwin Schollmayer | Use of rotigotine for treating the restless leg syndrome |
| US20060216336A1 (en) | 2002-05-07 | 2006-09-28 | Hans-Michael Wolff | Transdermal therapeutic system for Parkinson's Disease |
| KR20050045946A (ko) * | 2002-06-25 | 2005-05-17 | 애크럭스 디디에스 피티와이 리미티드 | 비정질 약학적 조성물을 이용한 경피전달속도의 제어 |
| US8246979B2 (en) | 2002-07-30 | 2012-08-21 | Ucb Pharma Gmbh | Transdermal delivery system for the administration of rotigotine |
| DE10234673B4 (de) | 2002-07-30 | 2007-08-16 | Schwarz Pharma Ag | Heißschmelz-TTS zur Verabreichung von Rotigotin und Verfahren zu seiner Herstellung sowie Verwendung von Rotigotin bei der Herstellung eines TTS im Heißschmelzverfahren |
| US8211462B2 (en) | 2002-07-30 | 2012-07-03 | Ucb Pharma Gmbh | Hot-melt TTS for administering rotigotine |
| US8246980B2 (en) | 2002-07-30 | 2012-08-21 | Ucb Pharma Gmbh | Transdermal delivery system |
| ES2239196T3 (es) | 2002-12-02 | 2005-09-16 | Schwarz Pharma Ag | Suministro iontoforetico de rotigotina para el tratamiento de la enfermedad de parkinson. |
| US9102726B2 (en) | 2002-12-04 | 2015-08-11 | Argos Therapeutics, Inc. | Nucleic acid of recombination expression vector encoding soluble forms of CD83, host cells transformed/transfected therewith and pharmaceutical compositions containing same |
| DE10261696A1 (de) | 2002-12-30 | 2004-07-15 | Schwarz Pharma Ag | Vorrichtung zur transdermalen Verabreichung von Rotigotin-Base |
| DE10334188B4 (de) | 2003-07-26 | 2007-07-05 | Schwarz Pharma Ag | Verwendung von Rotigotin zur Behandlung von Depressionen |
| DE10334187A1 (de) | 2003-07-26 | 2005-03-03 | Schwarz Pharma Ag | Substituierte 2-Aminotetraline zur Behandlung von Depressionen |
| DE10359528A1 (de) | 2003-12-18 | 2005-07-28 | Schwarz Pharma Ag | (S)-2-N-Propylamino-5-hydroxytetralin als D3-agonistisches Therapeutikum |
| EP1547592A1 (fr) | 2003-12-23 | 2005-06-29 | Schwarz Pharma Ag | Formulation intranasale contenant |
| DE10361258A1 (de) | 2003-12-24 | 2005-07-28 | Schwarz Pharma Ag | Verwendung von substituierten 2-Aminotetralinen zur vorbeugenden Behandlung von Morbus Parkinson |
| US20050197385A1 (en) | 2004-02-20 | 2005-09-08 | Schwarz Pharma Ag | Use of rotigotine for treatment or prevention of dopaminergic neuron loss |
| DE102004014841B4 (de) | 2004-03-24 | 2006-07-06 | Schwarz Pharma Ag | Verwendung von Rotigotin zur Behandlung und Prävention des Parkinson-Plus-Syndroms |
| TWI392670B (zh) | 2006-06-22 | 2013-04-11 | Ucb Pharma Gmbh | 經取代的2-胺基萘滿之於製造用於預防、減緩及/或治療各種類型疼痛之藥物上的用途 |
| EP1987815A1 (fr) | 2007-05-04 | 2008-11-05 | Schwarz Pharma Ag | Compositions pharmaceutiques à base d'agonistes dopaminergiques administrables par voie oro-naso-pharyngale pour la prévention et/ou le traitement de membres sans repos |
| NZ584363A (en) | 2007-11-28 | 2012-11-30 | Ucb Pharma Gmbh | Drug formulations of Rotigotine which comprise the thermodynamically stable polymorphic form 2 |
| EP2281559A1 (fr) | 2009-06-26 | 2011-02-09 | UCB Pharma GmbH | Composition pharmaceutique contenante un sel de rotigotine (sel d'acid ou Na), notament pour iontophorèse |
| LT3257504T (lt) | 2009-12-22 | 2024-08-26 | UCB Biopharma SRL | Polivinilpirolidonas, skirtas nekristalinės formos kietos rotigotino dispersijos stabilizavimui |
-
2002
- 2002-07-30 DE DE10234673A patent/DE10234673B4/de not_active Expired - Fee Related
-
2003
- 2003-07-29 AT AT03750403T patent/ATE324875T1/de active
- 2003-07-29 IL IL16607003A patent/IL166070A0/xx unknown
- 2003-07-29 JP JP2004525355A patent/JP4514608B2/ja not_active Expired - Fee Related
- 2003-07-29 CN CN03818378A patent/CN100574755C/zh not_active Expired - Fee Related
- 2003-07-29 MX MXPA04012150A patent/MXPA04012150A/es active IP Right Grant
- 2003-07-29 EP EP06005770A patent/EP1669063A1/fr not_active Withdrawn
- 2003-07-29 PL PL374852A patent/PL221308B1/pl unknown
- 2003-07-29 PT PT03750403T patent/PT1492517E/pt unknown
- 2003-07-29 RU RU2005105684/15A patent/RU2304434C2/ru active
- 2003-07-29 DE DE50303201T patent/DE50303201D1/de not_active Expired - Lifetime
- 2003-07-29 BR BR0311437-6A patent/BR0311437A/pt not_active Application Discontinuation
- 2003-07-29 CA CA2494361A patent/CA2494361C/fr not_active Expired - Fee Related
- 2003-07-29 US US10/523,908 patent/US9186335B2/en not_active Expired - Fee Related
- 2003-07-29 EP EP03750403A patent/EP1492517B1/fr not_active Expired - Lifetime
- 2003-07-29 ES ES03750403T patent/ES2263999T3/es not_active Expired - Lifetime
- 2003-07-29 KR KR1020057001416A patent/KR101041512B1/ko not_active Expired - Fee Related
- 2003-07-29 AU AU2003269859A patent/AU2003269859B2/en not_active Ceased
- 2003-07-29 WO PCT/EP2003/008348 patent/WO2004012721A2/fr not_active Ceased
- 2003-07-29 DK DK03750403T patent/DK1492517T3/da active
-
2005
- 2005-01-18 ZA ZA2005/00457A patent/ZA200500457B/en unknown
- 2005-02-16 NO NO20050835A patent/NO20050835L/no not_active Application Discontinuation
-
2006
- 2006-07-28 CY CY20061101048T patent/CY1105138T1/el unknown
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| NO20050835L (no) | Varmsmelte TTS for administrasjon av rotigotin | |
| ATE381926T2 (de) | Vitaminzusammenstellung mit verzögerter freigabe | |
| NO20100250L (no) | Farmasoytisk preparat som innbefatter en S1P reseptoragonist og en sukkeralkohol, og framgangsmate til fremstilling derav | |
| IS7076A (is) | Bólusetning með einföldum skammti af Mycoplasma hyopneumoniae, og notkun efnisins í lækningaskyni | |
| NO971206D0 (no) | Forlenget-frigjöringsformulering | |
| WO2004055006A8 (fr) | Nouveaux composes presentant un effet inhibiteur selectif de la gsk3 | |
| NO20013469D0 (no) | Fremgangsmåter for glukagonsuppresjon | |
| ES2154832T3 (es) | Sistema transcutaneo supersaturado para distribucion de medicamentos, y procedimientos de fabricacion asociados. | |
| DE60032032D1 (de) | Analgetische und antientzündliche tts enthaltend 4-biphenylylessigsäure zur äusseren anwendung | |
| MX2009005343A (es) | Sistema terapeutico transdermico con alto grado de utilizacion de sustancia activa y precision de dosificacion. | |
| DK1418951T3 (da) | Transdermalt teraeutisk system (TTS) med fentanyl som aktiv bestanddel | |
| NO20053663L (no) | Transdermal granistetron | |
| DK1578406T3 (da) | Farmaceutisk sammensætning med modificeret frigivelse | |
| NO20051370L (no) | Multilaminat baksidekonstruksjon som kan preges og paskrives | |
| WO2003015779A3 (fr) | Systeme therapeutique transdermique a regulation matricielle permettant l'administration de pramipexol et de ropinirol | |
| NO994620L (no) | Nye 2-(iminometyl)amino-fenyl-derivater, fremstilling, anvendelse som medisiner og farmasöytiske blandinger inneholdende disse | |
| DK1033990T3 (da) | 21-Hydroxy-6,19-oxidoprogesteron (21OH-6OP) dets anvendelse som medikament i behandling af glucocorticoidoverskud | |
| NO20052474L (no) | Amort form av esomeprazolsalter | |
| DE60019334D1 (de) | Antivirale arznei | |
| DK0979079T3 (da) | Anvendelse af tetrahydropyridinderivater til fremstilling af lægemidler til behandling af sygdomme, der medförer en demyelinisering | |
| DK1532986T3 (da) | Farmaceutisk sammensætning til behandling af rhinitis | |
| NO20064934L (no) | Fremgangsmate for fremstilling av et fast, farmasoytisk preparat | |
| NO20050771L (no) | Bicifadinformulering | |
| DK1494650T3 (da) | Farmaceutisk formulering, der indeholder melatonin | |
| ATE360428T1 (de) | Analgetisches arzneimittel |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC2A | Withdrawal, rejection or dismissal of laid open patent application |