NO20050904L - 13-leddete azalider og deres anvendelse som antibiotiske midler - Google Patents

13-leddete azalider og deres anvendelse som antibiotiske midler

Info

Publication number
NO20050904L
NO20050904L NO20050904A NO20050904A NO20050904L NO 20050904 L NO20050904 L NO 20050904L NO 20050904 A NO20050904 A NO 20050904A NO 20050904 A NO20050904 A NO 20050904A NO 20050904 L NO20050904 L NO 20050904L
Authority
NO
Norway
Prior art keywords
antibiotics
membered azalides
azalides
membered
Prior art date
Application number
NO20050904A
Other languages
English (en)
Other versions
NO329629B1 (no
Inventor
Barry James Morton
John Philip Dirlam
Robert John Rafka
Colman Brendan Ragan
Peter Bertinato
Alan Elwood Blize
Carl Bernard Ziegler
Original Assignee
Pfizer Prod Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22327457&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NO20050904(L) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Publication of NO20050904L publication Critical patent/NO20050904L/no
Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc
Publication of NO329629B1 publication Critical patent/NO329629B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biochemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biotechnology (AREA)
  • Public Health (AREA)
  • Genetics & Genomics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Pyrane Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicinal Preparation (AREA)
NO20050904A 1998-11-20 2005-02-18 13-leddete azalider NO329629B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10939998P 1998-11-20 1998-11-20
PCT/IB1999/001803 WO2000031097A1 (en) 1998-11-20 1999-11-09 13-membered azalides and their use as antibiotic agents

Publications (2)

Publication Number Publication Date
NO20050904L true NO20050904L (no) 2001-07-17
NO329629B1 NO329629B1 (no) 2010-11-22

Family

ID=22327457

Family Applications (3)

Application Number Title Priority Date Filing Date
NO20012464A NO319796B1 (no) 1998-11-20 1999-11-09 13-leddete azalider, fremgangsmåte for fremstilling og anvendelse derav samt farmasøytisk sammensetning.
NO20050893A NO330249B1 (no) 1998-11-20 2005-02-18 Azalider samt anvendelser og fremstilling derav, og farmasøytiske sammensetninger
NO20050904A NO329629B1 (no) 1998-11-20 2005-02-18 13-leddete azalider

Family Applications Before (2)

Application Number Title Priority Date Filing Date
NO20012464A NO319796B1 (no) 1998-11-20 1999-11-09 13-leddete azalider, fremgangsmåte for fremstilling og anvendelse derav samt farmasøytisk sammensetning.
NO20050893A NO330249B1 (no) 1998-11-20 2005-02-18 Azalider samt anvendelser og fremstilling derav, og farmasøytiske sammensetninger

Country Status (46)

Country Link
US (1) US6329345B1 (no)
EP (1) EP1131331B1 (no)
JP (1) JP3842973B2 (no)
KR (1) KR100477774B1 (no)
CN (2) CN101367853A (no)
AP (1) AP2001002142A0 (no)
AR (3) AR019496A1 (no)
AT (1) ATE260927T1 (no)
AU (1) AU766106B2 (no)
BG (1) BG65107B1 (no)
BR (2) BRPI9915480B8 (no)
CA (1) CA2351429C (no)
CO (1) CO5380019A1 (no)
CZ (1) CZ303099B6 (no)
DE (1) DE69915336T2 (no)
DK (1) DK1131331T3 (no)
DZ (1) DZ2944A1 (no)
EA (2) EA009729B1 (no)
EG (1) EG23823A (no)
ES (1) ES2216581T3 (no)
GT (1) GT199900198A (no)
HK (1) HK1041269A1 (no)
HR (1) HRP20010374B1 (no)
HU (1) HU229008B1 (no)
ID (1) ID28548A (no)
IL (3) IL142631A0 (no)
IS (1) IS2350B (no)
MA (1) MA26707A1 (no)
ME (1) ME00467B (no)
MY (1) MY122353A (no)
NO (3) NO319796B1 (no)
NZ (1) NZ511199A (no)
OA (1) OA11713A (no)
PA (1) PA8485601A1 (no)
PE (1) PE20001378A1 (no)
PL (1) PL198580B1 (no)
PT (1) PT1131331E (no)
RS (1) RS50302B (no)
SI (1) SI1131331T1 (no)
SK (1) SK284607B6 (no)
TN (1) TNSN99214A1 (no)
TW (2) TWI243825B (no)
UA (1) UA70972C2 (no)
UY (1) UY25805A1 (no)
WO (1) WO2000031097A1 (no)
ZA (1) ZA200104019B (no)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HN1998000086A (es) 1997-06-11 1999-03-08 Pfizer Prod Inc Derivados de 9 - desofo - 9 aza - 9a - homoeritromicina a - c - 4 sustituidos.
AP9801420A0 (en) * 1998-01-02 1998-12-31 Pfizer Prod Inc Novel macrolides.
UA70972C2 (uk) * 1998-11-20 2004-11-15 Пфайзер Продактс Інк. 13-членні азаліди і їх застосування як антибіотиків
EA200100983A1 (ru) * 1999-05-24 2002-10-31 Пфайзер Продактс Инк. Производные 13-метилэритромицина
US6465437B1 (en) * 1999-06-30 2002-10-15 Pfizer Inc. Diphosphate salt of a 4″-substituted-9-deoxo-9A-AZA-9A- homoerythromycin derivative and its pharmaceutical composition
CA2407448A1 (en) * 2000-04-27 2001-11-01 Pfizer Products Inc. The use of azalide antibiotic compositions for treating or preventing a bacterial or protozoal infection in mammals
JP4104463B2 (ja) * 2001-04-27 2008-06-18 ファイザー・プロダクツ・インク ４’’−置換された−９−デオキソ−９ａ−アザ−９ａ−ホモエリスロマイシン誘導体を製造するための方法
JP4311203B2 (ja) * 2001-08-08 2009-08-12 大正製薬株式会社 １１ａ−アザライド化合物及びその製造方法
ES2552682T3 (es) * 2003-03-10 2015-12-01 Merck Sharp & Dohme Corp. Agentes antibacterianos novedosos
WO2004108744A2 (en) * 2003-05-19 2004-12-16 Prasad K Deshpande Azalides and azaketolides having antimicrobial activity
US20070141086A1 (en) * 2003-11-21 2007-06-21 Ohara Michael K Use of antibiotics as vaccine adjuvants
JP5015016B2 (ja) * 2006-02-07 2012-08-29 大正製薬株式会社 １０ａ−アザライド化合物
US8293715B2 (en) 2007-08-06 2012-10-23 Taisho Pharmaceutical Co., Ltd. 10a-Azalide compound crosslinked at 10a- and 12-positions
US8299035B2 (en) 2008-05-15 2012-10-30 Taisho Pharmaceutucal Co., Ltd. 10a-azalide compound having 4-membered ring structure
CN103080121B (zh) * 2010-09-20 2015-11-25 瑞士诺华动物保健有限公司 用于制备在二脱氧甲基己糖环的C-4”处被环氧基团修饰的9-脱氧-9a-氮杂-9a-高红霉素A的新方法
CN102295672B (zh) * 2011-07-13 2014-06-04 武汉回盛生物科技有限公司 一种泰拉菌素的合成方法
EP2736915A1 (en) 2011-07-27 2014-06-04 Farma GRS, d.o.o. New crystalline forms of tulathromycin
CN102786569B (zh) * 2012-09-07 2016-12-07 安徽中升药业有限公司 泰拉霉素中间体及其制备方法与泰拉霉素的制备方法
WO2015014907A1 (en) * 2013-07-31 2015-02-05 Farma Grs, D.O.O. Process for preparation of tulathromycin
CN109748942A (zh) * 2014-05-16 2019-05-14 普莱柯生物工程股份有限公司 一种大环内酯类化合物
CN104725446B (zh) * 2015-03-26 2017-10-27 宁夏泰瑞制药股份有限公司 一种从泰拉霉素粗品中分离泰拉霉素a和泰拉霉素b的方法
ES3063764T3 (en) * 2018-11-19 2026-04-20 Zikani Therapeutics Inc C10-alkylene substituted 13-membered macrolides and uses thereof
KR20210123288A (ko) * 2018-11-19 2021-10-13 지카니 테라퓨틱스, 인크. C11-환식 치환된 13-원 마크롤라이드 및 이의 용도

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SI7910768A8 (en) 1979-04-02 1996-06-30 Pliva Pharm & Chem Works Process for pripering 11-aza-4-0-cladinosyl-6-0-desosaminyl-15-ethyl- 7,13,14-trihydroxy-3,5,7,9,12,14-hexamethyl- oxacyclopentadecane-2-one and their derivatives
SI8110592A8 (en) * 1981-03-06 1996-06-30 Pliva Pharm & Chem Works Process for preparing of n-methyl-11-aza-10-deoxo-10-dihydroerythromycine a and derivatives thereof
US4474768A (en) * 1982-07-19 1984-10-02 Pfizer Inc. N-Methyl 11-aza-10-deoxo-10-dihydro-erytromycin A, intermediates therefor
SI8611592A8 (en) * 1986-09-12 1995-04-30 Pliva Pharm & Chem Works Process for preparing complexes of N-methyl-11-aza-10-deoxo-10-dihydroeritromicine A and 11-aza-10-deoxo-10-dihydroeritromicine A with metals
US5106961A (en) 1987-05-26 1992-04-21 Eli Lilly And Company Erythromycin ring-contracted derivatives
SI9011409A (en) 1990-07-18 1995-10-31 Pliva Pharm & Chem Works O-methyl azitromycin derivates, methods and intermediates for their preparation and methods for preparation of pharmaceuticals products which comprise them
HRP931480B1 (en) * 1993-12-08 1997-08-31 Sour Pliva 9a-N-(N'-CARBAMONYL) and 9a-N-(N'-THIOCARBAMONYL) DERIVATES OF 9-DEOXO-9a-HOMOERYTHROMYCIN A
GB2327084A (en) * 1997-07-08 1999-01-13 Merck & Co Inc 9a-Aza-3-ketolide antibiotics
UA70972C2 (uk) * 1998-11-20 2004-11-15 Пфайзер Продактс Інк. 13-членні азаліди і їх застосування як антибіотиків

Also Published As

Publication number Publication date
ME00467B (me) 2011-10-10
UA70972C2 (uk) 2004-11-15
CZ303099B6 (cs) 2012-04-04
IS5918A (is) 2001-04-17
EP1131331A1 (en) 2001-09-12
OA11713A (en) 2005-01-25
PL347784A1 (en) 2002-04-22
UY25805A1 (es) 2001-08-27
AR059524A2 (es) 2008-04-09
NO319796B1 (no) 2005-09-19
SK6632001A3 (en) 2002-07-02
HRP20010374A2 (en) 2002-06-30
WO2000031097A1 (en) 2000-06-02
BG65107B1 (bg) 2007-02-28
CN101367853A (zh) 2009-02-18
EA005156B1 (ru) 2004-12-30
HK1041269A1 (zh) 2002-07-05
EA009729B1 (ru) 2008-02-28
TNSN99214A1 (fr) 2005-11-10
NO20012464L (no) 2001-07-17
US6329345B1 (en) 2001-12-11
KR100477774B1 (ko) 2005-03-21
RS50302B (sr) 2009-09-08
TWI243825B (en) 2005-11-21
PL198580B1 (pl) 2008-06-30
HUP0104313A3 (en) 2003-12-29
CN1326460A (zh) 2001-12-12
AR059523A2 (es) 2008-04-09
AU766106B2 (en) 2003-10-09
NO20050893L (no) 2001-07-17
MY122353A (en) 2006-04-29
HRP20010374B1 (en) 2006-09-30
PA8485601A1 (es) 2000-09-29
SK284607B6 (sk) 2005-07-01
JP3842973B2 (ja) 2006-11-08
NO330249B1 (no) 2011-03-14
CA2351429C (en) 2005-07-12
EP1131331B1 (en) 2004-03-03
AR019496A1 (es) 2002-02-20
IL142631A (en) 2010-05-31
BRPI9915480B1 (pt) 2015-12-29
NZ511199A (en) 2003-08-29
DE69915336D1 (de) 2004-04-08
IL142631A0 (en) 2002-03-10
JP2002530422A (ja) 2002-09-17
ES2216581T3 (es) 2004-10-16
MA26707A1 (fr) 2004-12-20
EA200100416A1 (ru) 2001-10-22
ZA200104019B (en) 2002-06-17
BR9915480A (pt) 2001-07-31
IL189430A0 (en) 2008-06-05
TWI243824B (en) 2005-11-21
ATE260927T1 (de) 2004-03-15
HU229008B1 (en) 2013-07-29
PT1131331E (pt) 2004-06-30
ID28548A (id) 2001-05-31
IL189430A (en) 2010-05-31
CZ20011754A3 (cs) 2002-03-13
EG23823A (en) 2007-09-19
DZ2944A1 (fr) 2004-03-15
HUP0104313A2 (hu) 2002-02-28
NO329629B1 (no) 2010-11-22
EA200400701A1 (ru) 2004-12-30
BRPI9915480B8 (pt) 2022-05-10
CA2351429A1 (en) 2000-06-02
NO20012464D0 (no) 2001-05-18
DE69915336T2 (de) 2005-01-13
SI1131331T1 (en) 2004-08-31
IS2350B (is) 2008-04-15
PE20001378A1 (es) 2000-12-14
AU1068600A (en) 2000-06-13
DK1131331T3 (da) 2004-06-14
CO5380019A1 (es) 2004-03-31
GT199900198A (es) 2001-05-11
BG105600A (en) 2001-12-29
TW200404077A (en) 2004-03-16
YU33401A (sh) 2004-05-12
KR20010086043A (ko) 2001-09-07
AP2001002142A0 (en) 2001-05-09

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Legal Events

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CHAD Change of the owner's name or address (par. 44 patent law, par. patentforskriften)

Owner name: ZOETIS P LLC, US

CHAD Change of the owner's name or address (par. 44 patent law, par. patentforskriften)

Owner name: ZOETIS SERVICES LLC, US

MK1K Patent expired