NO20051009L - Syntese av indoliziner - Google Patents

Syntese av indoliziner

Info

Publication number
NO20051009L
NO20051009L NO20051009A NO20051009A NO20051009L NO 20051009 L NO20051009 L NO 20051009L NO 20051009 A NO20051009 A NO 20051009A NO 20051009 A NO20051009 A NO 20051009A NO 20051009 L NO20051009 L NO 20051009L
Authority
NO
Norway
Prior art keywords
following formula
indolizines
represented
synthesis
reacting
Prior art date
Application number
NO20051009A
Other languages
English (en)
Inventor
Mitsunori Ono
Lijun Sun
Zhi-Qiang Xia
Teresa Przewloka
Shijie Zhang
Original Assignee
Synta Pharmaceuticals Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Synta Pharmaceuticals Corp filed Critical Synta Pharmaceuticals Corp
Publication of NO20051009L publication Critical patent/NO20051009L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Det er beskrevet fremgangsmåter for fremstilling av substituerte indoliziner representert ved følgende formel: omfattende omsetning av et substrat representert ved følgende formel: med enten sykliseringsreagens med følgende fonnel: eller, et reagens fremstilt ved omsetning av forbindelsene representert ved formelen nedenfor med et alkyleringsmiddel: Variablene i ovennevnte formler er definert heri.
NO20051009A 2002-09-13 2005-02-24 Syntese av indoliziner NO20051009L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US41067902P 2002-09-13 2002-09-13
PCT/US2003/028252 WO2004024727A2 (en) 2002-09-13 2003-09-10 Synthesis of indolizines

Publications (1)

Publication Number Publication Date
NO20051009L true NO20051009L (no) 2005-04-04

Family

ID=31994182

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20051009A NO20051009L (no) 2002-09-13 2005-02-24 Syntese av indoliziner

Country Status (10)

Country Link
US (1) US20040152897A1 (no)
EP (1) EP1537105A2 (no)
JP (1) JP2006504692A (no)
KR (1) KR20050052498A (no)
CN (1) CN1681813A (no)
AU (1) AU2003267071A1 (no)
CA (1) CA2496764A1 (no)
MX (1) MXPA05002745A (no)
NO (1) NO20051009L (no)
WO (1) WO2004024727A2 (no)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7749999B2 (en) 2003-09-11 2010-07-06 Itherx Pharmaceuticals, Inc. Alpha-ketoamides and derivatives thereof
WO2005099824A1 (en) * 2004-03-30 2005-10-27 Synta Pharmaceuticals, Corp. 1-glyoxylamide indolizines for treating lung and ovarian cancer
TWI440632B (zh) 2006-08-21 2014-06-11 Synta Pharmaceuticals Corp 用於治療增生性疾病的化合物
WO2009105257A1 (en) 2008-02-21 2009-08-27 Synta Pharmaceuticals Corp. Compounds for treating proliferative disorders
KR101117938B1 (ko) * 2009-09-10 2012-02-29 주식회사 엘지화학 신규한 헤테로고리 유도체 및 이를 이용한 유기 발광 소자
JOP20190024A1 (ar) 2016-08-26 2019-02-19 Gilead Sciences Inc مركبات بيروليزين بها استبدال واستخداماتها
PL3759109T3 (pl) 2018-02-26 2024-03-04 Gilead Sciences, Inc. Podstawione związki pirolizyny jako inhibitory replikacji hbv
CN116283972B (zh) * 2023-03-08 2025-08-26 安徽秀朗新材料科技有限公司 一种3-取代中氮茚衍生物的制备方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR9508298A (pt) * 1994-07-21 1998-11-03 Shionogi & Co Inibidores de indolizina de spla2
WO1998047507A1 (en) * 1997-04-24 1998-10-29 Shionogi & Co., Ltd. Method for the treatment of stroke using n-heterocyclic glyoxylamide compounds
JP2001514259A (ja) * 1997-08-29 2001-09-11 ゼネカ・リミテッド アミノメチルオキソオキサゾリジニルベンゼン誘導体
CA2459886A1 (en) * 2001-09-13 2003-03-20 Synta Pharmaceuticals Corp. 1-glyoxlylamide indolizines for treating cancer

Also Published As

Publication number Publication date
MXPA05002745A (es) 2005-06-03
EP1537105A2 (en) 2005-06-08
CA2496764A1 (en) 2004-03-25
KR20050052498A (ko) 2005-06-02
AU2003267071A1 (en) 2004-04-30
CN1681813A (zh) 2005-10-12
JP2006504692A (ja) 2006-02-09
WO2004024727A3 (en) 2004-06-03
US20040152897A1 (en) 2004-08-05
WO2004024727A2 (en) 2004-03-25

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Legal Events

Date Code Title Description
FC2A Withdrawal, rejection or dismissal of laid open patent application