NO20051367L - Nye 4-okso-4,6,7,8-tetrahydro-pyrrolo[1,2-a]pyrazin-6-karboksamid-forbindelser, fremgangsmate for deres fremstilling og farmasoytiske sammensetninger inneholdende dem - Google Patents

Nye 4-okso-4,6,7,8-tetrahydro-pyrrolo[1,2-a]pyrazin-6-karboksamid-forbindelser, fremgangsmate for deres fremstilling og farmasoytiske sammensetninger inneholdende dem

Info

Publication number: NO20051367L
Authority: NO; Norway
Prior art keywords: pyrrolo; pyrazine; tetrahydro; oxo; processes
Prior art date: 2004-03-19

Application number

NO20051367A

Other languages

English (en)

Norwegian (no)

Other versions

NO20051367D0 (no

Inventor

Guillaume De Nanteuil

Tony Verbeuren

Marie-Odile Vallez

Alain Rupin

Alain Benoist

Jean-Gilles Parmentier

Philippe Gloanec

Original Assignee

Servier Lab

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2004-03-19

Filing date

2005-03-16

Publication date

2005-09-20

2005-03-16 Application filed by Servier Lab filed Critical Servier Lab

2005-03-16 Publication of NO20051367D0 publication Critical patent/NO20051367D0/no

2005-09-20 Publication of NO20051367L publication Critical patent/NO20051367L/no

Links

UDHUGYDZHFRCQT-UHFFFAOYSA-N 4-oxo-7,8-dihydro-6h-pyrrolo[1,2-a]pyrazine-6-carboxamide Chemical class N1=CC(=O)N2C(C(=O)N)CCC2=C1 UDHUGYDZHFRCQT-UHFFFAOYSA-N 0.000 title 1
239000008194 pharmaceutical composition Substances 0.000 title 1
125000000217 alkyl group Chemical group 0.000 abstract 2
125000004429 atom Chemical group 0.000 abstract 2
125000004432 carbon atom Chemical group C* 0.000 abstract 2
-1 1-oxidopyridyl group Chemical group 0.000 abstract 1
UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
125000004423 acyloxy group Chemical group 0.000 abstract 1
125000003545 alkoxy group Chemical group 0.000 abstract 1
125000003118 aryl group Chemical group 0.000 abstract 1
125000005605 benzo group Chemical group 0.000 abstract 1
229910052799 carbon Inorganic materials 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
150000001924 cycloalkanes Chemical class 0.000 abstract 1
239000003814 drug Substances 0.000 abstract 1
229940079593 drug Drugs 0.000 abstract 1
229910052736 halogen Inorganic materials 0.000 abstract 1
150000002367 halogens Chemical class 0.000 abstract 1
125000001072 heteroaryl group Chemical group 0.000 abstract 1
229910052739 hydrogen Inorganic materials 0.000 abstract 1
239000001257 hydrogen Substances 0.000 abstract 1
125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A47—FURNITURE; DOMESTIC ARTICLES OR APPLIANCES; COFFEE MILLS; SPICE MILLS; SUCTION CLEANERS IN GENERAL
- A47J—KITCHEN EQUIPMENT; COFFEE MILLS; SPICE MILLS; APPARATUS FOR MAKING BEVERAGES
- A47J27/00—Cooking-vessels
- A47J27/14—Cooking-vessels for use in hotels, restaurants, or canteens
- A47J27/16—Cooking-vessels for use in hotels, restaurants, or canteens heated by steam
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
- A—HUMAN NECESSITIES
- A47—FURNITURE; DOMESTIC ARTICLES OR APPLIANCES; COFFEE MILLS; SPICE MILLS; SUCTION CLEANERS IN GENERAL
- A47J—KITCHEN EQUIPMENT; COFFEE MILLS; SPICE MILLS; APPARATUS FOR MAKING BEVERAGES
- A47J27/00—Cooking-vessels
- A47J27/12—Multiple-unit cooking vessels
- A47J27/13—Tier cooking-vessels
- A—HUMAN NECESSITIES
- A47—FURNITURE; DOMESTIC ARTICLES OR APPLIANCES; COFFEE MILLS; SPICE MILLS; SUCTION CLEANERS IN GENERAL
- A47J—KITCHEN EQUIPMENT; COFFEE MILLS; SPICE MILLS; APPARATUS FOR MAKING BEVERAGES
- A47J36/00—Parts, details or accessories of cooking-vessels
- A47J36/24—Warming devices

Landscapes

Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Heart & Thoracic Surgery (AREA)
Cardiology (AREA)
Vascular Medicine (AREA)
Diabetes (AREA)
Hematology (AREA)
Urology & Nephrology (AREA)
Food Science & Technology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Plural Heterocyclic Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

NO20051367A 2004-03-19 2005-03-16 Nye 4-okso-4,6,7,8-tetrahydro-pyrrolo[1,2-a]pyrazin-6-karboksamid-forbindelser, fremgangsmate for deres fremstilling og farmasoytiske sammensetninger inneholdende dem NO20051367L (no)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
FR0402841A FR2867780B1 (fr)	2004-03-19	2004-03-19	Nouveaux derives de 4-oxo-4,6,7,8-tetrahydropyrrolo (1,2-a) pyrazine-6-carboxamides, leur procede de preparation et les compositions pharmaceutiques qui les contiennent

Publications (2)

Publication Number	Publication Date
NO20051367D0 NO20051367D0 (no)	2005-03-16
NO20051367L true NO20051367L (no)	2005-09-20

Family

ID=34896643

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO20051367A NO20051367L (no)	2004-03-19	2005-03-16	Nye 4-okso-4,6,7,8-tetrahydro-pyrrolo[1,2-a]pyrazin-6-karboksamid-forbindelser, fremgangsmate for deres fremstilling og farmasoytiske sammensetninger inneholdende dem

Country Status (30)

Country	Link
US (2)	US7498330B2 (de)
EP (1)	EP1593682B1 (de)
JP (1)	JP2005272467A (de)
KR (1)	KR100741236B1 (de)
CN (1)	CN1297558C (de)
AR (1)	AR048277A1 (de)
AT (1)	ATE377601T1 (de)
AU (1)	AU2005201198B8 (de)
BR (1)	BRPI0500889A (de)
CA (1)	CA2500575C (de)
CY (1)	CY1107157T1 (de)
DE (1)	DE602005003161T2 (de)
DK (1)	DK1593682T3 (de)
EA (1)	EA008688B1 (de)
ES (1)	ES2296104T3 (de)
FR (1)	FR2867780B1 (de)
GE (1)	GEP20074035B (de)
HR (1)	HRP20070518T5 (de)
MA (1)	MA27547A1 (de)
MX (1)	MXPA05002985A (de)
MY (1)	MY136910A (de)
NO (1)	NO20051367L (de)
NZ (1)	NZ538935A (de)
PL (1)	PL1593682T3 (de)
PT (1)	PT1593682E (de)
RS (1)	RS50547B (de)
SG (1)	SG115741A1 (de)
SI (1)	SI1593682T1 (de)
UA (1)	UA83638C2 (de)
ZA (1)	ZA200502316B (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2867780B1 (fr) *	2004-03-19	2006-05-19	Servier Lab	Nouveaux derives de 4-oxo-4,6,7,8-tetrahydropyrrolo (1,2-a) pyrazine-6-carboxamides, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
CN101092372B (zh) *	2006-06-20	2011-09-21	上海药明康德新药开发有限公司	光学活性α-氨基庚二酸酯或单酯的合成方法
WO2025076476A2 (en) *	2023-10-06	2025-04-10	Omeros Corporation	Masp-2 inhibitors and methods of use

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2701951B1 (fr) *	1993-02-24	1995-06-09	Adir	Nouveaux derives peptidiques de l'acide boronique, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.
SE9301916D0 (sv) *	1993-06-03	1993-06-03	Ab Astra	New peptides derivatives
US6156540A (en) *	1993-12-22	2000-12-05	Human Genome Sciences, Inc.	Thrombin inhibitor
ZA951617B (en) *	1994-03-04	1997-02-27	Lilly Co Eli	Antithrombotic agents.
AU720616B2 (en) *	1996-02-22	2000-06-08	Merck & Co., Inc.	Pyridinone thrombin inhibitors
UA58636C2 (uk) *	1999-06-04	2003-08-15	Мерк Енд Ко., Інк.	Піразинонові інгібітори тромбіну, фармацевтична композиція, спосіб інгібування утворення тромбів у крові, спосіб лікування станів, пов'язаних із тромбоутворенням
FR2795072B1 (fr)	1999-06-15	2001-07-27	Adir	Nouveaux derives bicycliques d'amino-pyrazinones, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
FR2818277B1 (fr) *	2000-12-14	2003-01-24	Servier Lab	Nouveaux derives bicycliques d'amino-pyrazinones, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
FR2867780B1 (fr) *	2004-03-19	2006-05-19	Servier Lab	Nouveaux derives de 4-oxo-4,6,7,8-tetrahydropyrrolo (1,2-a) pyrazine-6-carboxamides, leur procede de preparation et les compositions pharmaceutiques qui les contiennent

2004
- 2004-03-19 FR FR0402841A patent/FR2867780B1/fr not_active Expired - Fee Related
2005
- 2005-03-04 SG SG200501360A patent/SG115741A1/en unknown
- 2005-03-14 US US11/079,638 patent/US7498330B2/en not_active Expired - Fee Related
- 2005-03-14 CA CA2500575A patent/CA2500575C/fr not_active Expired - Fee Related
- 2005-03-16 NO NO20051367A patent/NO20051367L/no unknown
- 2005-03-17 MY MYPI20051131A patent/MY136910A/en unknown
- 2005-03-17 MX MXPA05002985A patent/MXPA05002985A/es active IP Right Grant
- 2005-03-18 RS RSP-2007/0504A patent/RS50547B/sr unknown
- 2005-03-18 MA MA28165A patent/MA27547A1/fr unknown
- 2005-03-18 DK DK05290599T patent/DK1593682T3/da active
- 2005-03-18 PL PL05290599T patent/PL1593682T3/pl unknown
- 2005-03-18 UA UAA200502483A patent/UA83638C2/ru unknown
- 2005-03-18 EA EA200500379A patent/EA008688B1/ru not_active IP Right Cessation
- 2005-03-18 NZ NZ538935A patent/NZ538935A/en unknown
- 2005-03-18 ES ES05290599T patent/ES2296104T3/es not_active Expired - Lifetime
- 2005-03-18 AU AU2005201198A patent/AU2005201198B8/en not_active Ceased
- 2005-03-18 AT AT05290599T patent/ATE377601T1/de active
- 2005-03-18 PT PT05290599T patent/PT1593682E/pt unknown
- 2005-03-18 DE DE602005003161T patent/DE602005003161T2/de not_active Expired - Lifetime
- 2005-03-18 AR ARP050101066A patent/AR048277A1/es not_active Application Discontinuation
- 2005-03-18 EP EP05290599A patent/EP1593682B1/de not_active Expired - Lifetime
- 2005-03-18 SI SI200530111T patent/SI1593682T1/sl unknown
- 2005-03-18 GE GEAP8702A patent/GEP20074035B/en unknown
- 2005-03-18 JP JP2005079102A patent/JP2005272467A/ja active Pending
- 2005-03-18 ZA ZA200502316A patent/ZA200502316B/xx unknown
- 2005-03-19 KR KR1020050022977A patent/KR100741236B1/ko not_active Expired - Fee Related
- 2005-03-21 CN CNB200510055775XA patent/CN1297558C/zh not_active Expired - Fee Related
- 2005-03-21 BR BR0500889-1A patent/BRPI0500889A/pt not_active IP Right Cessation
2007
- 2007-11-09 HR HR20070518T patent/HRP20070518T5/xx unknown
2008
- 2008-01-28 CY CY20081100096T patent/CY1107157T1/el unknown
2009
- 2009-01-22 US US12/321,607 patent/US20090131668A1/en not_active Abandoned

Also Published As

Publication number	Publication date
ZA200502316B (en)	2005-10-03
KR100741236B1 (ko)	2007-07-19
HK1079775A1 (en)	2006-04-13
CN1680377A (zh)	2005-10-12
HRP20070518T3 (en)	2007-12-31
EA008688B1 (ru)	2007-06-29
KR20060044455A (ko)	2006-05-16
DE602005003161T2 (de)	2008-09-18
AU2005201198B2 (en)	2010-11-11
GEP20074035B (en)	2007-02-12
SG115741A1 (en)	2005-10-28
MY136910A (en)	2008-11-28
EA200500379A1 (ru)	2005-10-27
CY1107157T1 (el)	2012-10-24
PL1593682T3 (pl)	2008-03-31
HRP20070518T8 (en)	2008-10-31
HRP20070518T5 (en)	2008-10-31
AR048277A1 (es)	2006-04-12
EP1593682B1 (de)	2007-11-07
CA2500575A1 (fr)	2005-09-19
RS50547B (sr)	2010-05-07
DK1593682T3 (da)	2008-03-03
US20090131668A1 (en)	2009-05-21
DE602005003161D1 (de)	2007-12-20
NO20051367D0 (no)	2005-03-16
BRPI0500889A (pt)	2005-11-01
ATE377601T1 (de)	2007-11-15
AU2005201198B8 (en)	2011-03-10
AU2005201198A1 (en)	2005-10-06
SI1593682T1 (sl)	2008-02-29
ES2296104T3 (es)	2008-04-16
US20050209234A1 (en)	2005-09-22
MA27547A1 (fr)	2005-10-03
JP2005272467A (ja)	2005-10-06
EP1593682A3 (de)	2006-01-18
FR2867780B1 (fr)	2006-05-19
EP1593682A2 (de)	2005-11-09
PT1593682E (pt)	2007-12-06
US7498330B2 (en)	2009-03-03
UA83638C2 (ru)	2008-08-11
FR2867780A1 (fr)	2005-09-23
MXPA05002985A (es)	2005-10-06
CA2500575C (fr)	2010-06-22
CN1297558C (zh)	2007-01-31
NZ538935A (en)	2005-09-30

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