NO20052560L - Krystallinske fumaratsalter av N-[1-azabicyclo (2.2.2) okt-3yl] furo (2,3-C) pyridinyl-5-karboksamid samt sammensetninger og preparater derav. - Google Patents

Krystallinske fumaratsalter av N-[1-azabicyclo (2.2.2) okt-3yl] furo (2,3-C) pyridinyl-5-karboksamid samt sammensetninger og preparater derav.

Info

Publication number: NO20052560L
Authority: NO; Norway
Prior art keywords: furo; azabicyclo; carboxamide; oct; preparations
Prior art date: 2002-12-06

Application number

NO20052560A

Other languages

English (en)

Norwegian (no)

Other versions

NO20052560D0 (no

Inventor

Bradley Dee Hewitt

Ahmad Yahya Sheikh

Donn Gregory Wishka

Jon Gordon Selbo

David Warner Rappath

Original Assignee

Pharmacia & Upjohn Co Llc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2002-12-06

Filing date

2005-05-26

Publication date

2005-08-17

2005-05-26 Application filed by Pharmacia & Upjohn Co Llc filed Critical Pharmacia & Upjohn Co Llc

2005-05-26 Publication of NO20052560D0 publication Critical patent/NO20052560D0/no

2005-08-17 Publication of NO20052560L publication Critical patent/NO20052560L/no

Links

VZCYOOQTPOCHFL-OWOJBTEDSA-N Fumaric acid Chemical class OC(=O)\C=C\C(O)=O VZCYOOQTPOCHFL-OWOJBTEDSA-N 0.000 title abstract 3
238000002360 preparation method Methods 0.000 title abstract 3
239000000203 mixture Substances 0.000 title abstract 2
208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 2
HBAQYPYDRFILMT-UHFFFAOYSA-N 8-[3-(1-cyclopropylpyrazol-4-yl)-1H-pyrazolo[4,3-d]pyrimidin-5-yl]-3-methyl-3,8-diazabicyclo[3.2.1]octan-2-one Chemical class C1(CC1)N1N=CC(=C1)C1=NNC2=C1N=C(N=C2)N1C2C(N(CC1CC2)C)=O HBAQYPYDRFILMT-UHFFFAOYSA-N 0.000 abstract 1
102000015296 acetylcholine-gated cation-selective channel activity proteins Human genes 0.000 abstract 1
108040006409 acetylcholine-gated cation-selective channel activity proteins Proteins 0.000 abstract 1
201000010099 disease Diseases 0.000 abstract 1
208000035475 disorder Diseases 0.000 abstract 1
IPKZCLGGYKRDES-UHFFFAOYSA-N n-(1-azabicyclo[2.2.2]octan-3-yl)furo[2,3-c]pyridine-5-carboxamide Chemical class C1N(CC2)CCC2C1NC(=O)C(N=C1)=CC2=C1OC=C2 IPKZCLGGYKRDES-UHFFFAOYSA-N 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
- C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
- C07D453/04—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems having a quinolyl-4, a substituted quinolyl-4 or a alkylenedioxy-quinolyl-4 radical linked through only one carbon atom, attached in position 2, e.g. quinine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
- C07D491/044—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
- C07D491/048—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring the oxygen-containing ring being five-membered

Landscapes

Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Veterinary Medicine (AREA)
Neurology (AREA)
Public Health (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
Psychiatry (AREA)
Psychology (AREA)
Ophthalmology & Optometry (AREA)
Pain & Pain Management (AREA)
Hospice & Palliative Care (AREA)
Rheumatology (AREA)
Addiction (AREA)
Orthopedic Medicine & Surgery (AREA)
Physical Education & Sports Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

NO20052560A 2002-12-06 2005-05-26 Krystallinske fumaratsalter av N-[1-azabicyclo (2.2.2) okt-3yl] furo (2,3-C) pyridinyl-5-karboksamid samt sammensetninger og preparater derav. NO20052560L (no)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US43161902P	2002-12-06	2002-12-06
PCT/IB2003/005607 WO2004052894A1 (fr)	2002-12-06	2003-12-01	Sels fumarates cristallins de furo[2,3-c]pyridinyle carboxamide a substitution 1-azabicyclo [2.2.2]oct et compositions et preparations contenant lesdits sels

Publications (2)

Publication Number	Publication Date
NO20052560D0 NO20052560D0 (no)	2005-05-26
NO20052560L true NO20052560L (no)	2005-08-17

Family

ID=32507764

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO20052560A NO20052560L (no)	2002-12-06	2005-05-26	Krystallinske fumaratsalter av N-[1-azabicyclo (2.2.2) okt-3yl] furo (2,3-C) pyridinyl-5-karboksamid samt sammensetninger og preparater derav.

Country Status (22)

Country	Link
US (1)	US20050165047A1 (fr)
EP (1)	EP1572700A1 (fr)
JP (1)	JP2006510664A (fr)
KR (1)	KR20050087826A (fr)
CN (1)	CN1720248A (fr)
AR (1)	AR042295A1 (fr)
AU (1)	AU2003302911A1 (fr)
BR (1)	BR0317019A (fr)
CA (1)	CA2506529A1 (fr)
CR (1)	CR7859A (fr)
EA (1)	EA200500738A1 (fr)
EC (1)	ECSP055834A (fr)
HR (1)	HRP20050494A2 (fr)
IS (1)	IS7844A (fr)
MA (1)	MA27604A1 (fr)
MX (1)	MXPA05005943A (fr)
NO (1)	NO20052560L (fr)
OA (1)	OA12968A (fr)
PL (1)	PL377052A1 (fr)
TW (1)	TW200427691A (fr)
WO (1)	WO2004052894A1 (fr)
ZA (1)	ZA200503988B (fr)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6670178B1 (en)	1992-07-10	2003-12-30	Transkaryotic Therapies, Inc.	In Vivo production and delivery of insulinotropin for gene therapy
DE10164139A1 (de)	2001-12-27	2003-07-10	Bayer Ag	2-Heteroarylcarbonsäureamide
EP1603585A2 (fr)	2003-03-14	2005-12-14	Bristol-Myers Squibb Company	Polynucleotide codant un nouveau variant de recepteur de hm74, hgprbmy74 couple a une proteine g humaine
US8383657B2 (en)	2007-12-21	2013-02-26	Abbott Laboratories	Thiazolylidine urea and amide derivatives and methods of use thereof
EP2633868A1 (fr) *	2008-02-13	2013-09-04	Targacept, Inc.	Combinaison d'agonistes nicotiniques alpha 7 et d'antipsychotiques
TW201031664A (en)	2009-01-26	2010-09-01	Targacept Inc	Preparation and therapeutic applications of (2S,3R)-N-2-((3-pyridinyl)methyl)-1-azabicyclo[2.2.2]oct-3-yl)-3,5-difluorobenzamide
KR20180101641A (ko)	2010-05-17	2018-09-12	포럼 파마슈티칼즈 인크.	(R)-7-클로로-N-(퀴누클리딘-3-일)벤조[b]티오펜-2-카르복사미드 히드로클로리드 모노히드레이트의 결정질 형태
EP3461481A1 (fr)	2012-05-08	2019-04-03	Forum Pharmaceuticals Inc.	Procédés de maintien, de traitement ou d'amélioration de la fonction cognitive

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO1988002751A1 (fr) *	1986-10-13	1988-04-21	Asahi Kasei Kogyo Kabushiki Kaisha	Derives de pyridine
AR036040A1 (es) *	2001-06-12	2004-08-04	Upjohn Co	Compuestos de heteroarilo multiciclicos sustituidos con quinuclidinas y composiciones farmaceuticas que los contienen

2003
- 2003-12-01 KR KR1020057010196A patent/KR20050087826A/ko not_active Ceased
- 2003-12-01 BR BR0317019-5A patent/BR0317019A/pt unknown
- 2003-12-01 MX MXPA05005943A patent/MXPA05005943A/es not_active Application Discontinuation
- 2003-12-01 PL PL377052A patent/PL377052A1/pl not_active Application Discontinuation
- 2003-12-01 OA OA1200500173A patent/OA12968A/en unknown
- 2003-12-01 AU AU2003302911A patent/AU2003302911A1/en not_active Abandoned
- 2003-12-01 CA CA002506529A patent/CA2506529A1/fr not_active Abandoned
- 2003-12-01 HR HR20050494A patent/HRP20050494A2/hr not_active Application Discontinuation
- 2003-12-01 WO PCT/IB2003/005607 patent/WO2004052894A1/fr not_active Ceased
- 2003-12-01 EP EP03812627A patent/EP1572700A1/fr not_active Withdrawn
- 2003-12-01 CN CNA200380105166XA patent/CN1720248A/zh active Pending
- 2003-12-01 JP JP2004558940A patent/JP2006510664A/ja active Pending
- 2003-12-01 EA EA200500738A patent/EA200500738A1/ru unknown
- 2003-12-04 AR ARP030104471A patent/AR042295A1/es unknown
- 2003-12-05 TW TW092134360A patent/TW200427691A/zh unknown
2004
- 2004-10-08 US US10/962,071 patent/US20050165047A1/en not_active Abandoned
2005
- 2005-05-12 IS IS7844A patent/IS7844A/is unknown
- 2005-05-17 ZA ZA200503988A patent/ZA200503988B/en unknown
- 2005-05-26 NO NO20052560A patent/NO20052560L/no not_active Application Discontinuation
- 2005-06-03 EC EC2005005834A patent/ECSP055834A/es unknown
- 2005-06-06 CR CR7859A patent/CR7859A/es not_active Application Discontinuation
- 2005-06-06 MA MA28315A patent/MA27604A1/fr unknown

Also Published As

Publication number	Publication date
CA2506529A1 (fr)	2004-06-24
US20050165047A1 (en)	2005-07-28
EP1572700A1 (fr)	2005-09-14
MA27604A1 (fr)	2005-11-01
KR20050087826A (ko)	2005-08-31
EA200500738A1 (ru)	2005-12-29
WO2004052894A1 (fr)	2004-06-24
HRP20050494A2 (en)	2005-10-31
TW200427691A (en)	2004-12-16
AU2003302911A1 (en)	2004-06-30
MXPA05005943A (es)	2005-08-18
AR042295A1 (es)	2005-06-15
CN1720248A (zh)	2006-01-11
OA12968A (en)	2006-10-13
BR0317019A (pt)	2005-10-25
JP2006510664A (ja)	2006-03-30
CR7859A (es)	2005-07-08
IS7844A (is)	2005-05-12
ECSP055834A (es)	2005-08-11
NO20052560D0 (no)	2005-05-26
ZA200503988B (en)	2006-09-27
PL377052A1 (pl)	2006-01-23

Legal Events

Date	Code	Title	Description
2007-08-27	FC2A	Withdrawal, rejection or dismissal of laid open patent application

Publication	Publication Date	Title
NO308772B1 (no)	2000-10-30	Sublingual eller buckal farmasoytisk blanding inneholdende trans-5-klor-2-metyl-2,3,3a,12b-tetrahydro-1H-dibenz[2,3:6,7]oksepino[4,5-c]pyrrol, samt anvendelse av forbindelsen for fremstilling av farmasoytisk blanding
WO2003093250A3 (fr)	2004-12-23	Modulateurs allosteriques positifs de recepteur nicotinique de l'acetylcholine
IS1904B (is)	2003-11-20	Hliðstæðar aðferðir við framleiðslu á nýjum (R)-5-karbamóýl-8-flúor-3-N,N-tvíútskiptum-amínó-3,4-díhýdró-2H-1-bensópýrönum
NO20052560L (no)	2005-08-17	Krystallinske fumaratsalter av N-[1-azabicyclo (2.2.2) okt-3yl] furo (2,3-C) pyridinyl-5-karboksamid samt sammensetninger og preparater derav.
RU94046220A (ru)	1996-09-27	N/гетеро/-арил-n/гетеро/-тетралин-алкилпиперазин, обладающий серотонинергической, допаминергической и адренергической активностью, способ их получения, терапевтическая композиция, применение
IL78661A (en)	1992-08-18	Bone targeted inhibitors of carbonic anhydrase and methods for the preparation thereof
GB9109972D0 (en)	1991-07-03	Therapeutic compounds
RU94039284A (ru)	1996-08-10	Производные пиперазина, способ их получения, фармкомпозиция и ее использование
NO903384L (no)	1991-02-04	Fremgangsmaate for fremstilling av 4-(n-substituert amino)-2-butynyl-1-urinstoffer og -tiourinstoffer og derivater derav.
HUT52377A (en)	1990-07-28	Process for producing pharmaceutical compositions comprising 3-substituted-2-oxindole-1-carboxamide derivatives as active ingredient
SI1556045T1 (sl)	2007-02-28	Derivati 4-aminopiperidina, postopek izdelave in uporaba v medicini
AU567018B2 (en)	1987-11-05	Prazosin-pirbuterol combination for bronchoduation
ZA891769B (en)	1989-12-27	Heterocyclic compounds
IL75012A0 (en)	1985-08-30	Triazolopyrimidone compounds
DK0793665T3 (da)	2001-12-31	Heterocykliske forbindelser og deres fremstilling og anvendelse