NO20053367L - Sigmareseptor-defisiente, mutante ikke-humane pattedyr og anvendelser derav. - Google Patents

Sigmareseptor-defisiente, mutante ikke-humane pattedyr og anvendelser derav.

Info

Publication number
NO20053367L
NO20053367L NO20053367A NO20053367A NO20053367L NO 20053367 L NO20053367 L NO 20053367L NO 20053367 A NO20053367 A NO 20053367A NO 20053367 A NO20053367 A NO 20053367A NO 20053367 L NO20053367 L NO 20053367L
Authority
NO
Norway
Prior art keywords
receptor
mutant
deficient
sigma
sigmar
Prior art date
Application number
NO20053367A
Other languages
English (en)
Norwegian (no)
Other versions
NO20053367D0 (no
Inventor
Daniel Zamanillo Castanedo
Lluis Montoliu Jose
Francina Langa Vives
Alfonso Javier Lavado Judez
Victoria Eugenia Tova Herrador
Original Assignee
Esteve Labor Dr
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Esteve Labor Dr filed Critical Esteve Labor Dr
Publication of NO20053367D0 publication Critical patent/NO20053367D0/no
Publication of NO20053367L publication Critical patent/NO20053367L/no

Links

Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K67/00—Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
    • A01K67/027—New or modified breeds of vertebrates
    • A01K67/0275—Genetically modified vertebrates, e.g. transgenic
    • A01K67/0276—Knock-out vertebrates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/8509—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells for producing genetically modified animals, e.g. transgenic
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/07—Animals genetically altered by homologous recombination
    • A01K2217/072—Animals genetically altered by homologous recombination maintaining or altering function, i.e. knock in
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/07—Animals genetically altered by homologous recombination
    • A01K2217/075—Animals genetically altered by homologous recombination inducing loss of function, i.e. knock out
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2227/00—Animals characterised by species
    • A01K2227/10—Mammal
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2227/00—Animals characterised by species
    • A01K2227/10—Mammal
    • A01K2227/105—Murine
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2267/00—Animals characterised by purpose
    • A01K2267/03—Animal model, e.g. for test or diseases
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2267/00—Animals characterised by purpose
    • A01K2267/03—Animal model, e.g. for test or diseases
    • A01K2267/035—Animal model for multifactorial diseases
    • A01K2267/0356—Animal model for processes and diseases of the central nervous system, e.g. stress, learning, schizophrenia, pain, epilepsy

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Environmental Sciences (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Husbandry (AREA)
  • Biodiversity & Conservation Biology (AREA)
  • Biochemistry (AREA)
  • Public Health (AREA)
  • Physics & Mathematics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
NO20053367A 2002-12-09 2005-07-11 Sigmareseptor-defisiente, mutante ikke-humane pattedyr og anvendelser derav. NO20053367L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ES200202815A ES2209650B2 (es) 2002-12-09 2002-12-09 Mamiferos no humanos mutantes deficientes en receptores sigma y sus aplicaciones.
PCT/ES2003/000624 WO2004052092A1 (es) 2002-12-09 2003-12-09 Mamíferos no humanos mutantes deficientes en receptores sigma y sus aplicaciones

Publications (2)

Publication Number Publication Date
NO20053367D0 NO20053367D0 (no) 2005-07-11
NO20053367L true NO20053367L (no) 2005-07-11

Family

ID=32480022

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20053367A NO20053367L (no) 2002-12-09 2005-07-11 Sigmareseptor-defisiente, mutante ikke-humane pattedyr og anvendelser derav.

Country Status (14)

Country Link
US (1) US8003847B2 (de)
EP (2) EP1584232B1 (de)
JP (1) JP4515915B2 (de)
AR (1) AR042300A1 (de)
AT (1) ATE360362T1 (de)
AU (1) AU2003285369C1 (de)
CA (1) CA2508697A1 (de)
CY (1) CY1106675T1 (de)
DE (1) DE60313499T2 (de)
DK (1) DK1584232T3 (de)
ES (2) ES2209650B2 (de)
NO (1) NO20053367L (de)
PT (1) PT1584232E (de)
WO (1) WO2004052092A1 (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007047978A2 (en) 2005-10-21 2007-04-26 Braincells, Inc. Modulation of neurogenesis by pde inhibition
EP2314289A1 (de) 2005-10-31 2011-04-27 Braincells, Inc. Gaba-rezeptor-vermittelte modulation von neurogenese
US20100216734A1 (en) 2006-03-08 2010-08-26 Braincells, Inc. Modulation of neurogenesis by nootropic agents
EP2021000A2 (de) 2006-05-09 2009-02-11 Braincells, Inc. Neurogenese mittels angiotensin-modulation
US7678808B2 (en) 2006-05-09 2010-03-16 Braincells, Inc. 5 HT receptor mediated neurogenesis
WO2008030651A1 (en) 2006-09-08 2008-03-13 Braincells, Inc. Combinations containing a 4-acylaminopyridine derivative
US20100184806A1 (en) 2006-09-19 2010-07-22 Braincells, Inc. Modulation of neurogenesis by ppar agents
US20100216805A1 (en) 2009-02-25 2010-08-26 Braincells, Inc. Modulation of neurogenesis using d-cycloserine combinations

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5464764A (en) 1989-08-22 1995-11-07 University Of Utah Research Foundation Positive-negative selection methods and vectors
US6239326B1 (en) 1996-11-07 2001-05-29 The Wistar Institute Of Anatomy And Biology Sparc-deficient transgenic mice
US6194633B1 (en) 1998-01-26 2001-02-27 University Of Iowa Research Foundation Non-human animal having a functionally disrupted SLP-76 gene
US6207876B1 (en) 1998-04-28 2001-03-27 Board Of Regents, The University Of Texas System Adenosine deaminase deficient transgenic mice and methods for the use thereof
US6252132B1 (en) 1998-11-02 2001-06-26 Institut Pasteur Mutant mouse containing a knockout mutation in DNA encoding an endogenous alpha 4 subunit of nicotinic acetylcholine receptor
US6245965B1 (en) 1999-01-29 2001-06-12 St. Jude Children's Research Hospital Knockout mice and cells that lack p19INK4d and p27KIP1 activity and methods of use thereof
US6245963B1 (en) 1999-05-28 2001-06-12 Academia Sinica Knockout-transgenic mouse model of spinal muscular atrophy
JP4470077B2 (ja) * 1999-11-16 2010-06-02 和男 鈴木 好中球走化性因子ｌｅｃｔ２遺伝子の機能が欠損したマウス

Also Published As

Publication number Publication date
CY1106675T1 (el) 2012-05-23
JP2006508673A (ja) 2006-03-16
US8003847B2 (en) 2011-08-23
AU2003285369C1 (en) 2010-02-18
US20050132429A1 (en) 2005-06-16
ES2209650A1 (es) 2004-06-16
EP1752540A3 (de) 2007-11-21
AU2003285369B2 (en) 2009-09-10
NO20053367D0 (no) 2005-07-11
DE60313499T2 (de) 2008-01-03
CA2508697A1 (en) 2004-06-24
ES2209650B2 (es) 2006-11-01
AU2003285369A1 (en) 2004-06-30
WO2004052092A1 (es) 2004-06-24
AR042300A1 (es) 2005-06-15
DE60313499D1 (de) 2007-06-06
JP4515915B2 (ja) 2010-08-04
ES2286484T3 (es) 2007-12-01
PT1584232E (pt) 2007-07-24
ATE360362T1 (de) 2007-05-15
HK1083987A1 (en) 2006-07-21
EP1752540A2 (de) 2007-02-14
DK1584232T3 (da) 2007-07-30
EP1584232B1 (de) 2007-04-25
EP1584232A1 (de) 2005-10-12

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