NO20053473L - Fremgangsmate for fremstilling av R,R (eller S,S) konfigurasjonen av glykopyrroniumstereoisomerer - Google Patents

Fremgangsmate for fremstilling av R,R (eller S,S) konfigurasjonen av glykopyrroniumstereoisomerer

Info

Publication number: NO20053473L
Authority: NO; Norway
Prior art keywords: glycopyrronium; stereoisomers; preparing; configuration; glycopyrronium stereoisomers
Prior art date: 2002-12-18

Application number

NO20053473A

Other languages

English (en)

Other versions

NO330851B1 (no

NO20053473D0 (no

Inventor

Christian R Noe

Martin R Walter

Original Assignee

Pharmacon Forschung & Beratung Gmbh

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2002-12-18

Filing date

2005-07-15

Publication date

2005-09-19

2005-07-15 Application filed by Pharmacon Forschung & Beratung Gmbh filed Critical Pharmacon Forschung & Beratung Gmbh

2005-07-15 Publication of NO20053473D0 publication Critical patent/NO20053473D0/no

2005-09-19 Publication of NO20053473L publication Critical patent/NO20053473L/no

2011-08-01 Publication of NO330851B1 publication Critical patent/NO330851B1/no

Links

ANGKOCUUWGHLCE-HKUYNNGSSA-N [(3s)-1,1-dimethylpyrrolidin-1-ium-3-yl] (2r)-2-cyclopentyl-2-hydroxy-2-phenylacetate Chemical class C1[N+](C)(C)CC[C@@H]1OC(=O)[C@](O)(C=1C=CC=CC=1)C1CCCC1 ANGKOCUUWGHLCE-HKUYNNGSSA-N 0.000 title 1
238000004519 manufacturing process Methods 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/06—Anti-spasmodics, e.g. drugs for colics, esophagic dyskinesia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/06—Anti-spasmodics
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/12—Oxygen or sulfur atoms

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Engineering & Computer Science (AREA)
Animal Behavior & Ethology (AREA)
Bioinformatics & Cheminformatics (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Urology & Nephrology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Pyrrole Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

NO20053473A 2002-12-18 2005-07-15 Fremgangsmate for fremstilling av R,R- (eller S,S-) konfigurasjonen av glykopyrroniumstereoisomerer NO330851B1 (no)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
AT0189602A AT412088B (de)	2002-12-18	2002-12-18	Verfahren zur herstellung der r,r oder s,s konfigurierten glycopyrronium-isomere
PCT/EP2003/014432 WO2004054971A1 (de)	2002-12-18	2003-12-18	Verfaren zur herstellung des r,r (oder s,s) konfugurierten glycopyrronium-stereoisomers

Publications (3)

Publication Number	Publication Date
NO20053473D0 NO20053473D0 (no)	2005-07-15
NO20053473L true NO20053473L (no)	2005-09-19
NO330851B1 NO330851B1 (no)	2011-08-01

Family

ID=31192804

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO20053473A NO330851B1 (no)	2002-12-18	2005-07-15	Fremgangsmate for fremstilling av R,R- (eller S,S-) konfigurasjonen av glykopyrroniumstereoisomerer

Country Status (15)

Country	Link
US (1)	US7569598B2 (no)
EP (1)	EP1572641B1 (no)
JP (1)	JP2007524565A (no)
CN (1)	CN100349867C (no)
AT (2)	AT412088B (no)
AU (1)	AU2003290075B2 (no)
CA (1)	CA2510280C (no)
DK (1)	DK1572641T3 (no)
ES (1)	ES2383799T3 (no)
NO (1)	NO330851B1 (no)
NZ (1)	NZ541098A (no)
PL (1)	PL214802B1 (no)
PT (1)	PT1572641E (no)
RU (1)	RU2337096C2 (no)
WO (1)	WO2004054971A1 (no)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB0504463D0 (en) *	2005-03-03	2005-04-13	Arakis Ltd	Method of crystallisation and purification
PL2417106T3 (pl) *	2009-04-09	2017-05-31	Novartis Ag	Sposób wytwarzania soli pirolidyniowych
EP2580195B1 (en) *	2010-06-14	2014-12-03	Chiesi Farmaceutici S.p.A.	Crystal form of glycopyrronium chloride
CN103159659A (zh) *	2011-12-19	2013-06-19	沈阳药科大学	一种毒蕈碱受体拮抗剂格隆溴铵的制备方法
LT2607351T (lt) *	2011-12-22	2017-06-12	Cerbios-Pharma S.A.	Ciklinių tretinių aminų nepertraukiamo alkilinimo būdas
CN102627595A (zh) *	2012-03-09	2012-08-08	徐奎	一种制备格隆溴铵的方法
KR20150119468A (ko)	2013-02-28	2015-10-23	더미라, 인코포레이티드	글리코피롤레이트 염
US9006462B2 (en)	2013-02-28	2015-04-14	Dermira, Inc.	Glycopyrrolate salts
US8558008B2 (en)	2013-02-28	2013-10-15	Dermira, Inc.	Crystalline glycopyrrolate tosylate
CN104586841A (zh) *	2013-10-30	2015-05-06	中国药科大学	(3r,2’r)-格隆溴铵作为m3毒蕈碱性受体拮抗剂在制药中的用途
CN107304178B (zh) *	2016-04-21	2020-03-27	辽宁药联制药有限公司	一种毒蕈碱受体拮抗剂格隆溴铵手性对映体的制备方法
CN107345945B (zh) *	2016-05-05	2019-12-17	辽宁药联制药有限公司	一种拆分格隆溴铵对映体及杂质检查的高效液相色谱方法
CN113234003B (zh) *	2021-04-23	2024-02-02	广东嘉博制药有限公司	一种格隆溴铵及其制备方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DK0937041T3 (da) *	1996-11-11	2003-08-11	Christian R Noe	Anvendelse af et farmaceutisk egnet salt af (3R,2'R)-3-[(cyclopentil-hydroxyphenylacetyl)oxyl]-1,1-dimethyl-pyrrolidinium til fremstilling af et lægemiddel

2002
- 2002-12-18 AT AT0189602A patent/AT412088B/de not_active IP Right Cessation
2003
- 2003-12-18 PL PL377441A patent/PL214802B1/pl unknown
- 2003-12-18 AT AT03782435T patent/ATE548348T1/de active
- 2003-12-18 CN CNB2003801098187A patent/CN100349867C/zh not_active Expired - Fee Related
- 2003-12-18 NZ NZ541098A patent/NZ541098A/en not_active IP Right Cessation
- 2003-12-18 PT PT03782435T patent/PT1572641E/pt unknown
- 2003-12-18 CA CA2510280A patent/CA2510280C/en not_active Expired - Fee Related
- 2003-12-18 US US10/540,187 patent/US7569598B2/en not_active Expired - Lifetime
- 2003-12-18 JP JP2004560470A patent/JP2007524565A/ja active Pending
- 2003-12-18 EP EP03782435A patent/EP1572641B1/de not_active Expired - Lifetime
- 2003-12-18 AU AU2003290075A patent/AU2003290075B2/en not_active Ceased
- 2003-12-18 RU RU2005122497/04A patent/RU2337096C2/ru active
- 2003-12-18 WO PCT/EP2003/014432 patent/WO2004054971A1/de not_active Ceased
- 2003-12-18 ES ES03782435T patent/ES2383799T3/es not_active Expired - Lifetime
- 2003-12-18 DK DK03782435.6T patent/DK1572641T3/da active
2005
- 2005-07-15 NO NO20053473A patent/NO330851B1/no not_active IP Right Cessation

Also Published As

Publication number	Publication date
EP1572641A1 (de)	2005-09-14
RU2337096C2 (ru)	2008-10-27
AU2003290075A1 (en)	2004-07-09
CA2510280C (en)	2011-09-27
ATA18962002A (de)	2004-02-15
NZ541098A (en)	2008-08-29
AT412088B (de)	2004-09-27
DK1572641T3 (da)	2012-07-02
WO2004054971A1 (de)	2004-07-01
PL214802B1 (pl)	2013-09-30
US7569598B2 (en)	2009-08-04
RU2005122497A (ru)	2006-01-20
NO330851B1 (no)	2011-08-01
ES2383799T3 (es)	2012-06-26
EP1572641B1 (de)	2012-03-07
CN100349867C (zh)	2007-11-21
JP2007524565A (ja)	2007-08-30
PT1572641E (pt)	2012-06-15
US20060167275A1 (en)	2006-07-27
CA2510280A1 (en)	2004-07-01
NO20053473D0 (no)	2005-07-15
PL377441A1 (pl)	2006-02-06
AU2003290075B2 (en)	2009-01-29
CN1751022A (zh)	2006-03-22
ATE548348T1 (de)	2012-03-15

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Legal Events

Date	Code	Title	Description
2022-07-25	MM1K	Lapsed by not paying the annual fees