NO20053473L - Fremgangsmate for fremstilling av R,R (eller S,S) konfigurasjonen av glykopyrroniumstereoisomerer - Google Patents

Fremgangsmate for fremstilling av R,R (eller S,S) konfigurasjonen av glykopyrroniumstereoisomerer

Info

Publication number: NO20053473L
Authority: NO; Norway
Prior art keywords: glycopyrronium; stereoisomers; preparing; configuration; glycopyrronium stereoisomers
Prior art date: 2002-12-18

Application number

NO20053473A

Other languages

English (en)

Other versions

NO20053473D0 (no

NO330851B1 (no

Inventor

Christian R Noe

Martin R Walter

Original Assignee

Pharmacon Forschung & Beratung Gmbh

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2002-12-18

Filing date

2005-07-15

Publication date

2005-09-19

2005-07-15 Application filed by Pharmacon Forschung & Beratung Gmbh filed Critical Pharmacon Forschung & Beratung Gmbh

2005-07-15 Publication of NO20053473D0 publication Critical patent/NO20053473D0/no

2005-09-19 Publication of NO20053473L publication Critical patent/NO20053473L/no

2011-08-01 Publication of NO330851B1 publication Critical patent/NO330851B1/no

Links

ANGKOCUUWGHLCE-HKUYNNGSSA-N [(3s)-1,1-dimethylpyrrolidin-1-ium-3-yl] (2r)-2-cyclopentyl-2-hydroxy-2-phenylacetate Chemical class C1[N+](C)(C)CC[C@@H]1OC(=O)[C@](O)(C=1C=CC=CC=1)C1CCCC1 ANGKOCUUWGHLCE-HKUYNNGSSA-N 0.000 title 1
238000004519 manufacturing process Methods 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/06—Anti-spasmodics, e.g. drugs for colics, esophagic dyskinesia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/06—Anti-spasmodics
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/12—Oxygen or sulfur atoms

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Engineering & Computer Science (AREA)
Animal Behavior & Ethology (AREA)
Bioinformatics & Cheminformatics (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Urology & Nephrology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Pyrrole Compounds (AREA)
Plural Heterocyclic Compounds (AREA)

NO20053473A 2002-12-18 2005-07-15 Fremgangsmate for fremstilling av R,R- (eller S,S-) konfigurasjonen av glykopyrroniumstereoisomerer NO330851B1 (no)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
AT0189602A AT412088B (de)	2002-12-18	2002-12-18	Verfahren zur herstellung der r,r oder s,s konfigurierten glycopyrronium-isomere
PCT/EP2003/014432 WO2004054971A1 (de)	2002-12-18	2003-12-18	Verfaren zur herstellung des r,r (oder s,s) konfugurierten glycopyrronium-stereoisomers

Publications (3)

Publication Number	Publication Date
NO20053473D0 NO20053473D0 (no)	2005-07-15
NO20053473L true NO20053473L (no)	2005-09-19
NO330851B1 NO330851B1 (no)	2011-08-01

Family

ID=31192804

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO20053473A NO330851B1 (no)	2002-12-18	2005-07-15	Fremgangsmate for fremstilling av R,R- (eller S,S-) konfigurasjonen av glykopyrroniumstereoisomerer

Country Status (15)

Country	Link
US (1)	US7569598B2 (no)
EP (1)	EP1572641B1 (no)
JP (1)	JP2007524565A (no)
CN (1)	CN100349867C (no)
AT (2)	AT412088B (no)
AU (1)	AU2003290075B2 (no)
CA (1)	CA2510280C (no)
DK (1)	DK1572641T3 (no)
ES (1)	ES2383799T3 (no)
NO (1)	NO330851B1 (no)
NZ (1)	NZ541098A (no)
PL (1)	PL214802B1 (no)
PT (1)	PT1572641E (no)
RU (1)	RU2337096C2 (no)
WO (1)	WO2004054971A1 (no)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB0504463D0 (en) *	2005-03-03	2005-04-13	Arakis Ltd	Method of crystallisation and purification
ES2617680T3 (es) *	2009-04-09	2017-06-19	Novartis Ag	Proceso para la preparación de sales de pirrolidinio
RU2569852C2 (ru) *	2010-06-14	2015-11-27	КЬЕЗИ ФАРМАЧЕУТИЧИ С.п.А.	Кристаллическая форма гликопиррония хлорида
CN103159659A (zh) *	2011-12-19	2013-06-19	沈阳药科大学	一种毒蕈碱受体拮抗剂格隆溴铵的制备方法
SMT201700269T1 (it) *	2011-12-22	2017-07-18	Cerbios Pharma Sa	Procedimento in continuo per l'alchilazione di ammine terziarie cicliche
CN102627595A (zh) *	2012-03-09	2012-08-08	徐奎	一种制备格隆溴铵的方法
JP6114841B2 (ja)	2013-02-28	2017-04-12	ダーミラ，インク．Ｄｅｒｍｉｒａ，Ｉｎｃ．	グリコピロレート塩
US8558008B2 (en)	2013-02-28	2013-10-15	Dermira, Inc.	Crystalline glycopyrrolate tosylate
US9006462B2 (en)	2013-02-28	2015-04-14	Dermira, Inc.	Glycopyrrolate salts
CN104586841A (zh) *	2013-10-30	2015-05-06	中国药科大学	(3r,2’r)-格隆溴铵作为m3毒蕈碱性受体拮抗剂在制药中的用途
CN107304178B (zh) *	2016-04-21	2020-03-27	辽宁药联制药有限公司	一种毒蕈碱受体拮抗剂格隆溴铵手性对映体的制备方法
CN107345945B (zh) *	2016-05-05	2019-12-17	辽宁药联制药有限公司	一种拆分格隆溴铵对映体及杂质检查的高效液相色谱方法
CN113234003B (zh) *	2021-04-23	2024-02-02	广东嘉博制药有限公司	一种格隆溴铵及其制备方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CN100391942C (zh) *	1996-11-11	2008-06-04	索佛特克两合公司	对映异构纯的碱性芳基-环烷基-羟基羧酸酯,其制备方法及其在药品中的应用

2002
- 2002-12-18 AT AT0189602A patent/AT412088B/de not_active IP Right Cessation
2003
- 2003-12-18 AU AU2003290075A patent/AU2003290075B2/en not_active Ceased
- 2003-12-18 ES ES03782435T patent/ES2383799T3/es not_active Expired - Lifetime
- 2003-12-18 AT AT03782435T patent/ATE548348T1/de active
- 2003-12-18 PL PL377441A patent/PL214802B1/pl unknown
- 2003-12-18 NZ NZ541098A patent/NZ541098A/en not_active IP Right Cessation
- 2003-12-18 DK DK03782435.6T patent/DK1572641T3/da active
- 2003-12-18 WO PCT/EP2003/014432 patent/WO2004054971A1/de not_active Ceased
- 2003-12-18 RU RU2005122497/04A patent/RU2337096C2/ru active
- 2003-12-18 US US10/540,187 patent/US7569598B2/en not_active Expired - Lifetime
- 2003-12-18 PT PT03782435T patent/PT1572641E/pt unknown
- 2003-12-18 EP EP03782435A patent/EP1572641B1/de not_active Expired - Lifetime
- 2003-12-18 CN CNB2003801098187A patent/CN100349867C/zh not_active Expired - Fee Related
- 2003-12-18 CA CA2510280A patent/CA2510280C/en not_active Expired - Fee Related
- 2003-12-18 JP JP2004560470A patent/JP2007524565A/ja active Pending
2005
- 2005-07-15 NO NO20053473A patent/NO330851B1/no not_active IP Right Cessation

Also Published As

Publication number	Publication date
CN1751022A (zh)	2006-03-22
ES2383799T3 (es)	2012-06-26
CN100349867C (zh)	2007-11-21
WO2004054971A1 (de)	2004-07-01
AU2003290075A1 (en)	2004-07-09
ATE548348T1 (de)	2012-03-15
NO20053473D0 (no)	2005-07-15
CA2510280A1 (en)	2004-07-01
NZ541098A (en)	2008-08-29
EP1572641B1 (de)	2012-03-07
ATA18962002A (de)	2004-02-15
EP1572641A1 (de)	2005-09-14
RU2005122497A (ru)	2006-01-20
PL377441A1 (pl)	2006-02-06
PT1572641E (pt)	2012-06-15
US7569598B2 (en)	2009-08-04
NO330851B1 (no)	2011-08-01
US20060167275A1 (en)	2006-07-27
AT412088B (de)	2004-09-27
AU2003290075B2 (en)	2009-01-29
PL214802B1 (pl)	2013-09-30
CA2510280C (en)	2011-09-27
RU2337096C2 (ru)	2008-10-27
JP2007524565A (ja)	2007-08-30
DK1572641T3 (da)	2012-07-02

Similar Documents

Publication	Publication Date	Title
IS7755A (is)	2005-03-17	Aðferð við framleiðslu á (S,S)-cis-2-benshýdríl-3-bensýlamínókínuklídín
ATE304358T1 (de)	2005-09-15	(s,s)-reboxetin zur behandlung von migränekopfschmerzen
IL197312A0 (en)	2011-07-31	Amyloid-??(1-42) oligomers, derivatives thereof antibodies for the same, method for production and use thereof
DE602004017731D1 (de)	2008-12-24	Verfahren zur herstellung von 1-ä(benzimidazol-1-yl)chinolin-8-ylüpiperidin-4-ylaminderivaten
DE60234952D1 (de)	2010-02-11	VERFAHREN ZUR HERSTELLUNG VON HEXAHYDROFUROc2,3-BÜFURAN-3-OL
NO20053473L (no)	2005-09-19	Fremgangsmate for fremstilling av R,R (eller S,S) konfigurasjonen av glykopyrroniumstereoisomerer
NO20044814L (no)	2004-01-07	Fremgangsmate for fremstilling av combretastaniner
DE502005001841D1 (de)	2007-12-13	Verfahren zur herstellung von 1,4-diphenylazetidinon-derivaten
NO20054535L (no)	2005-11-25	Bifunksjonelle heterocykliske forbindelser og fremgangsmater for fremstilling og anvendelse av samme
DE602005014280D1 (de)	2009-06-10	Verfahren zur herstellung von ä1,4,5ü-oxadiazepinderivaten
DE60220554D1 (de)	2007-07-19	Mikrowelleninduzierter prozess zur herstellung von substituierten 4-vinylphenolen
DE60210778D1 (de)	2006-05-24	Verfahren zur herstellung von 4-amino-2,5-bisheterocyclylchinazolinen
DE60336822D1 (de)	2011-06-01	Verfahren zur herstellung von kristallinem 1,2-polybutadien
DE502005007702D1 (de)	2009-08-27	Verfahren zur herstellung von terrylen-3,4:11,12-t
NO20052471D0 (no)	2005-05-23	Fremgangsmate for fremstilling av 3-metyltiopropanal.
EP1565448A4 (en)	2008-04-23	PROCESS FOR THE PREPARATION OF 10H-DIBENZOçB, F] ç1,4] THIAZEPIN-11-ON
NO20020308D0 (no)	2002-01-21	Fremgangsmåte for fremstilling av epothiolon B og derivater, såvel som mellomprodukter for fremgangsmåten
DK1599433T3 (da)	2007-04-16	Fremgangsmåde til fremstilling af de enantiomere former af cis-konfigurerede 1,3-cyclohexandiolderivater
FI20020163A0 (fi)	2002-01-29	Menetelmä selluloosakarbamaatin valmistamiseksi
ITMI20021533A1 (it)	2004-01-12	Processo per la preparazione di 2-acetossimetil-4-alo-but-1-il acetati
ITBO20020602A1 (it)	2004-03-25	Apparecchiatura per la realizzazione di decori artistici,
DE602004004215D1 (de)	2007-02-22	Verfahren zur Herstellung von hochreinen, niedrigmolekularen Heparinen
DE502004011536D1 (de)	2010-09-23	verfahren zur herstellung von bengamide-derivaten
ITMI20020227A1 (it)	2003-08-07	Procedimento per la preparazione di alchiluree da o ,d-dimetil ditiocarbonato
DE50307320D1 (de)	2007-07-05	Verfahren zur herstellung von 1,2-dichlorethan mittels direktchlorierung

Legal Events

Date	Code	Title	Description
2022-07-25	MM1K	Lapsed by not paying the annual fees