NO20053561L - Mettede kinoksalinderivater og deres anvendelse som metabotrofe og glutamatreseptorligander - Google Patents
Mettede kinoksalinderivater og deres anvendelse som metabotrofe og glutamatreseptorliganderInfo
- Publication number
- NO20053561L NO20053561L NO20053561A NO20053561A NO20053561L NO 20053561 L NO20053561 L NO 20053561L NO 20053561 A NO20053561 A NO 20053561A NO 20053561 A NO20053561 A NO 20053561A NO 20053561 L NO20053561 L NO 20053561L
- Authority
- NO
- Norway
- Prior art keywords
- receptor ligands
- glutamate receptor
- metabotrophic
- saturated
- quinoxaline derivatives
- Prior art date
Links
- 239000003446 ligand Substances 0.000 title abstract 2
- 102000018899 Glutamate Receptors Human genes 0.000 title 1
- 108010027915 Glutamate Receptors Proteins 0.000 title 1
- 125000001567 quinoxalinyl group Chemical class N1=C(C=NC2=CC=CC=C12)* 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- 102000016193 Metabotropic glutamate receptors Human genes 0.000 abstract 1
- 108010010914 Metabotropic glutamate receptors Proteins 0.000 abstract 1
- 239000000543 intermediate Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 229920006395 saturated elastomer Polymers 0.000 abstract 1
- 239000012453 solvate Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/36—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems
- C07D241/38—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems with only hydrogen or carbon atoms directly attached to the ring nitrogen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/498—Pyrazines or piperazines ortho- and peri-condensed with carbocyclic ring systems, e.g. quinoxaline, phenazine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/36—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems
- C07D241/38—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems with only hydrogen or carbon atoms directly attached to the ring nitrogen atoms
- C07D241/40—Benzopyrazines
- C07D241/44—Benzopyrazines with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/36—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems
- C07D241/50—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems with hetero atoms directly attached to ring nitrogen atoms
- C07D241/52—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Pain & Pain Management (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US44388903P | 2003-01-31 | 2003-01-31 | |
| US53063203P | 2003-12-19 | 2003-12-19 | |
| PCT/US2004/002131 WO2004069813A1 (en) | 2003-01-31 | 2004-01-26 | Saturated quinoxaline derivatives and their use as metabotropic glutamate receptor ligands |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| NO20053561D0 NO20053561D0 (no) | 2005-07-20 |
| NO20053561L true NO20053561L (no) | 2005-10-28 |
Family
ID=32853344
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20053561A NO20053561L (no) | 2003-01-31 | 2005-07-20 | Mettede kinoksalinderivater og deres anvendelse som metabotrofe og glutamatreseptorligander |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US20050004130A1 (pt) |
| EP (1) | EP1587796A1 (pt) |
| JP (1) | JP2006516628A (pt) |
| KR (1) | KR20060004907A (pt) |
| AU (1) | AU2004209540A1 (pt) |
| BR (1) | BRPI0406810A (pt) |
| CA (1) | CA2513824A1 (pt) |
| MX (1) | MXPA05008186A (pt) |
| NO (1) | NO20053561L (pt) |
| WO (1) | WO2004069813A1 (pt) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE0303492D0 (sv) * | 2003-12-19 | 2003-12-19 | Astrazeneca Ab | New use VII |
| EP2258358A3 (en) | 2005-08-26 | 2011-09-07 | Braincells, Inc. | Neurogenesis with acetylcholinesterase inhibitor |
| EP2275095A3 (en) | 2005-08-26 | 2011-08-17 | Braincells, Inc. | Neurogenesis by muscarinic receptor modulation |
| EP1940389A2 (en) | 2005-10-21 | 2008-07-09 | Braincells, Inc. | Modulation of neurogenesis by pde inhibition |
| AU2006308889A1 (en) | 2005-10-31 | 2007-05-10 | Braincells, Inc. | GABA receptor mediated modulation of neurogenesis |
| US20070244143A1 (en) * | 2006-03-08 | 2007-10-18 | Braincells, Inc | Modulation of neurogenesis by nootropic agents |
| US20100216734A1 (en) * | 2006-03-08 | 2010-08-26 | Braincells, Inc. | Modulation of neurogenesis by nootropic agents |
| US20100009983A1 (en) * | 2006-05-09 | 2010-01-14 | Braincells, Inc. | 5 ht receptor mediated neurogenesis |
| JP2009536667A (ja) * | 2006-05-09 | 2009-10-15 | ブレインセルス，インコーポレイティド | ５ｈｔ受容体介在性の神経新生 |
| EP2382975A3 (en) | 2006-05-09 | 2012-02-29 | Braincells, Inc. | Neurogenesis by modulating angiotensin |
| AU2007292848A1 (en) * | 2006-09-08 | 2008-03-13 | Braincells, Inc. | Combinations containing a 4-acylaminopyridine derivative |
| AU2007299920A1 (en) * | 2006-09-19 | 2008-03-27 | Braincells, Inc. | PPAR Mediated Modulation of Neurogenesis |
| US20100184806A1 (en) | 2006-09-19 | 2010-07-22 | Braincells, Inc. | Modulation of neurogenesis by ppar agents |
| WO2010099217A1 (en) | 2009-02-25 | 2010-09-02 | Braincells, Inc. | Modulation of neurogenesis using d-cycloserine combinations |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS59231068A (ja) * | 1983-06-13 | 1984-12-25 | Sumitomo Chem Co Ltd | 酸イミド系化合物およびその製造法 |
| US4709052A (en) * | 1983-05-31 | 1987-11-24 | Sumitomo Chemical Company, Limited | Soil disease-controlling imides |
| JPS59227845A (ja) * | 1983-06-09 | 1984-12-21 | Sumitomo Chem Co Ltd | 酸アミド系化合物 |
| JPS59222403A (ja) * | 1983-05-31 | 1984-12-14 | Sumitomo Chem Co Ltd | 土壌病害防除剤 |
| JPS6041602A (ja) * | 1983-08-17 | 1985-03-05 | Sumitomo Chem Co Ltd | 土壌病害防除剤 |
| JPS59225101A (ja) * | 1983-06-03 | 1984-12-18 | Sumitomo Chem Co Ltd | 土壌病害防除剤 |
| JPS6042303A (ja) * | 1983-08-18 | 1985-03-06 | Sumitomo Chem Co Ltd | シアノアセトアニリド誘導体を有効成分とする植物病害防除剤 |
| DD220602A1 (de) * | 1983-09-13 | 1985-04-03 | Fahlberg List Veb | Verfahren zur herstellung von chinoxalin-2-thiocarbonsaeureamiden |
| JPS60214706A (ja) * | 1984-04-05 | 1985-10-28 | Sumitomo Chem Co Ltd | 土壌病害防除剤 |
| JPS60224663A (ja) * | 1984-04-23 | 1985-11-09 | Sumitomo Chem Co Ltd | 酸アミド系化合物 |
| JP2759257B2 (ja) * | 1993-09-28 | 1998-05-28 | 大塚製薬株式会社 | 糖尿病治療剤 |
| JP3964478B2 (ja) * | 1995-06-30 | 2007-08-22 | エーザイ・アール・アンド・ディー・マネジメント株式会社 | ヘテロ環含有カルボン酸誘導体及びそれを含有する医薬 |
| CN1158264C (zh) * | 1997-11-21 | 2004-07-21 | Nps药物有限公司 | 用于治疗中枢神经系统疾病的代谢性谷氨酸受体拮抗剂 |
| US6429207B1 (en) * | 1997-11-21 | 2002-08-06 | Nps Pharmaceuticals, Inc. | Metabotropic glutamate receptor antagonists and their use for treating central nervous system diseases |
| DK1196397T3 (da) * | 1999-06-02 | 2006-01-02 | Nps Pharma Inc | Metabotrope glutamatreceptorantagonister og anvendelse deraf til behandling af sygdomme i centralnervesystemet |
| ES2546386T3 (es) * | 1999-07-20 | 2015-09-23 | Dow Agrosciences, Llc | Amidas aromáticas heterocíclicas fungicidas y sus composiciones, métodos de uso y preparación |
| PL205059B1 (pl) * | 1999-08-20 | 2010-03-31 | Dow Agrosciences Llc | Heterocykliczny amid aromatyczny, jego kompozycja grzybobójcza oraz sposób zwalczania lub zapobiegania zakażeniom grzybami |
-
2004
- 2004-01-26 WO PCT/US2004/002131 patent/WO2004069813A1/en not_active Ceased
- 2004-01-26 KR KR1020057013475A patent/KR20060004907A/ko not_active Withdrawn
- 2004-01-26 BR BR0406810-6A patent/BRPI0406810A/pt not_active IP Right Cessation
- 2004-01-26 EP EP04705287A patent/EP1587796A1/en not_active Withdrawn
- 2004-01-26 MX MXPA05008186A patent/MXPA05008186A/es not_active Application Discontinuation
- 2004-01-26 CA CA002513824A patent/CA2513824A1/en not_active Abandoned
- 2004-01-26 AU AU2004209540A patent/AU2004209540A1/en not_active Abandoned
- 2004-01-26 JP JP2006503034A patent/JP2006516628A/ja active Pending
- 2004-01-30 US US10/766,948 patent/US20050004130A1/en not_active Abandoned
-
2005
- 2005-07-20 NO NO20053561A patent/NO20053561L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| EP1587796A1 (en) | 2005-10-26 |
| WO2004069813A1 (en) | 2004-08-19 |
| MXPA05008186A (es) | 2005-10-05 |
| AU2004209540A1 (en) | 2004-08-19 |
| BRPI0406810A (pt) | 2005-12-27 |
| JP2006516628A (ja) | 2006-07-06 |
| NO20053561D0 (no) | 2005-07-20 |
| KR20060004907A (ko) | 2006-01-16 |
| US20050004130A1 (en) | 2005-01-06 |
| CA2513824A1 (en) | 2004-08-19 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC2A | Withdrawal, rejection or dismissal of laid open patent application |