NO20053587L - 3-(3,5-diokso-4,5-dihydro-3H-(1,2,4)triazin-2-yl-)benzamidderivater som P2X7-inhibitorer for behandling av inflammatoriske sykdommer. - Google Patents

3-(3,5-diokso-4,5-dihydro-3H-(1,2,4)triazin-2-yl-)benzamidderivater som P2X7-inhibitorer for behandling av inflammatoriske sykdommer.

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Publication number
NO20053587L
NO20053587L NO20053587A NO20053587A NO20053587L NO 20053587 L NO20053587 L NO 20053587L NO 20053587 A NO20053587 A NO 20053587A NO 20053587 A NO20053587 A NO 20053587A NO 20053587 L NO20053587 L NO 20053587L
Authority
NO
Norway
Prior art keywords
treatment
inhibitors
inflammatory diseases
triazin
dioxo
Prior art date
Application number
NO20053587A
Other languages
English (en)
Norwegian (no)
Inventor
Mark Anthony Dombroski
Allen Jacob Duplantier
Original Assignee
Pfizer Prod Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc
Publication of NO20053587L publication Critical patent/NO20053587L/no

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    • C07D253/02—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00 not condensed with other rings
    • C07D253/06—1,2,4-Triazines
    • C07D253/065—1,2,4-Triazines having three double bonds between ring members or between ring members and non-ring members
    • C07D253/07—1,2,4-Triazines having three double bonds between ring members or between ring members and non-ring members with hetero atoms, or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D253/075—Two hetero atoms, in positions 3 and 5
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    • C07D253/06—1,2,4-Triazines
    • C07D253/065—1,2,4-Triazines having three double bonds between ring members or between ring members and non-ring members
    • C07D253/07—1,2,4-Triazines having three double bonds between ring members or between ring members and non-ring members with hetero atoms, or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
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NO20053587A 2002-12-31 2005-07-22 3-(3,5-diokso-4,5-dihydro-3H-(1,2,4)triazin-2-yl-)benzamidderivater som P2X7-inhibitorer for behandling av inflammatoriske sykdommer. NO20053587L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US43750502P 2002-12-31 2002-12-31
PCT/IB2003/006254 WO2004058270A1 (fr) 2002-12-31 2003-12-19 Derives de 3-(3,5-dioxo-4,5-dihydro-3h-(1,2,4)triazin-2-yl)-benzamide utilises comme inhibiteurs de p2x7 pour le traitement de maladies inflammatoires

Publications (1)

Publication Number Publication Date
NO20053587L true NO20053587L (no) 2005-08-09

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NO20053587A NO20053587L (no) 2002-12-31 2005-07-22 3-(3,5-diokso-4,5-dihydro-3H-(1,2,4)triazin-2-yl-)benzamidderivater som P2X7-inhibitorer for behandling av inflammatoriske sykdommer.

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US (4) US6974812B2 (fr)
EP (1) EP1581232B1 (fr)
JP (1) JP4560411B2 (fr)
KR (1) KR100689138B1 (fr)
CN (1) CN1732006A (fr)
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Families Citing this family (62)

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Publication number Priority date Publication date Assignee Title
PA8557501A1 (es) * 2001-11-12 2003-06-30 Pfizer Prod Inc Benzamida, heteroarilamida y amidas inversas
US7071223B1 (en) * 2002-12-31 2006-07-04 Pfizer, Inc. Benzamide inhibitors of the P2X7 receptor
PA8591801A1 (es) * 2002-12-31 2004-07-26 Pfizer Prod Inc Inhibidores benzamidicos del receptor p2x7.
EP1626962B1 (fr) 2003-05-12 2007-02-28 Pfizer Products Inc. Inhibiteurs benzamidiques du recepteur p2x7
EP1837330B1 (fr) * 2003-05-12 2012-10-24 Pfizer Products Inc. Inhibiteurs benzamidiques du recepteur P2X7
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US6974812B2 (en) 2005-12-13
TW200413336A (en) 2004-08-01
PA8591801A1 (es) 2004-07-26
MXPA05006749A (es) 2005-09-08
TNSN05174A1 (fr) 2007-05-14
US20060040939A1 (en) 2006-02-23
US7407956B2 (en) 2008-08-05
NL1025148C2 (nl) 2007-09-28
UA82346C2 (xx) 2008-04-10
CA2512193C (fr) 2010-09-07
AR042673A1 (es) 2005-06-29
US7176202B2 (en) 2007-02-13
JP2006513206A (ja) 2006-04-20
MA27575A1 (fr) 2005-10-03
RS20050490A (sr) 2007-11-15
GT200300297A (es) 2004-09-21
ECSP055884A (es) 2005-09-20
AP1997A (en) 2009-04-22
IS7840A (is) 2005-05-09
AP2005003350A0 (en) 2005-09-30
NI200500118A (es) 2006-05-19
US20040180894A1 (en) 2004-09-16
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AU2003285716B2 (en) 2010-03-18
ES2464350T3 (es) 2014-06-02
HRP20050609A2 (en) 2006-02-28
IL168513A (en) 2011-06-30
WO2004058270A1 (fr) 2004-07-15
TWI288133B (en) 2007-10-11
EA200500777A1 (ru) 2005-12-29
CA2512193A1 (fr) 2004-07-15
AU2003285716A1 (en) 2004-07-22
US20070281939A1 (en) 2007-12-06
CR7884A (es) 2005-08-05
US20090042886A1 (en) 2009-02-12
JP4560411B2 (ja) 2010-10-13
EP1581232A1 (fr) 2005-10-05
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ZA200503912B (en) 2006-07-26

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