NO20053748L - Pyrrolopyridazinderivater. - Google Patents

Pyrrolopyridazinderivater.

Info

Publication number
NO20053748L
NO20053748L NO20053748A NO20053748A NO20053748L NO 20053748 L NO20053748 L NO 20053748L NO 20053748 A NO20053748 A NO 20053748A NO 20053748 A NO20053748 A NO 20053748A NO 20053748 L NO20053748 L NO 20053748L
Authority
NO
Norway
Prior art keywords
pyrrolopyridazine derivatives
pyrrolopyridazine
derivatives
pde
tnf
Prior art date
Application number
NO20053748A
Other languages
English (en)
Norwegian (no)
Other versions
NO20053748D0 (no
Inventor
Kazuhiko Ohne
Yuki Sawada
Tsuyoshi Mizutani
Kenichiro Imamura
Yoshito Abe
Makoto Inoue
Kozo Sawada
Mitsuaki Okumura
Original Assignee
Fujisawa Pharmaceutical Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from AU2003900189A external-priority patent/AU2003900189A0/en
Priority claimed from AU2003903628A external-priority patent/AU2003903628A0/en
Application filed by Fujisawa Pharmaceutical Co filed Critical Fujisawa Pharmaceutical Co
Publication of NO20053748D0 publication Critical patent/NO20053748D0/no
Publication of NO20053748L publication Critical patent/NO20053748L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Communicable Diseases (AREA)
  • Neurosurgery (AREA)
  • Oncology (AREA)
  • Dermatology (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Neurology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Virology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
NO20053748A 2003-01-09 2005-08-04 Pyrrolopyridazinderivater. NO20053748L (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
AU2003900189A AU2003900189A0 (en) 2003-01-09 2003-01-09 Heterocyclic derivatives
AU2003903628A AU2003903628A0 (en) 2003-07-14 2003-07-14 Pyrrolopyridazine derivatives
PCT/JP2003/017091 WO2004063197A1 (en) 2003-01-09 2003-12-26 Pyrrolopyridazine derivatives

Publications (2)

Publication Number Publication Date
NO20053748D0 NO20053748D0 (no) 2005-08-04
NO20053748L true NO20053748L (no) 2005-10-07

Family

ID=32714072

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20053748A NO20053748L (no) 2003-01-09 2005-08-04 Pyrrolopyridazinderivater.

Country Status (21)

Country Link
US (2) US7153854B2 (de)
EP (1) EP1581535B3 (de)
JP (1) JP4671104B2 (de)
KR (1) KR101026819B1 (de)
AR (1) AR042833A1 (de)
AT (1) ATE376549T1 (de)
BR (1) BR0317358A (de)
CA (1) CA2513081C (de)
CY (1) CY1107084T1 (de)
DE (1) DE60317102T3 (de)
DK (1) DK1581535T5 (de)
ES (1) ES2291729T7 (de)
IL (1) IL169500A0 (de)
MX (1) MXPA05007462A (de)
NO (1) NO20053748L (de)
NZ (1) NZ541232A (de)
PL (1) PL378245A1 (de)
PT (1) PT1581535E (de)
RU (1) RU2328499C2 (de)
TW (1) TWI332004B (de)
WO (1) WO2004063197A1 (de)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101026819B1 (ko) 2003-01-09 2011-04-04 아스테라스 세이야쿠 가부시키가이샤 피롤로피리다진 유도체
US7030112B2 (en) * 2003-03-25 2006-04-18 Bristol-Myers Squibb Company Pyrrolopyridazine compounds and methods of use thereof for the treatment of proliferative disorders
GB0411056D0 (en) 2004-05-18 2004-06-23 Novartis Ag Organic compounds
WO2006004191A1 (en) * 2004-07-05 2006-01-12 Astellas Pharma Inc. Pyrrolopyridazine derivatives which inhibit pde iv and tnf alfa
ES2319797T3 (es) * 2004-07-05 2009-05-12 Astellas Pharma Inc. Derivados de pirazolopiridina.
GB0422057D0 (en) * 2004-10-05 2004-11-03 Astrazeneca Ab Novel compounds
GB0601951D0 (en) 2006-01-31 2006-03-15 Novartis Ag Organic compounds
JP2010508315A (ja) 2006-10-30 2010-03-18 ノバルティス アーゲー 抗炎症剤としてのヘテロ環式化合物
JP2009114123A (ja) * 2007-11-06 2009-05-28 Astellas Pharma Inc ２−アシル−１−アミノピロール化合物の新規製造法
AU2008326309C1 (en) * 2007-11-21 2015-03-12 Decode Genetics Ehf Biaryl PDE4 inhibitors for treating pulmonary and cardiovascular disorders
KR20100113557A (ko) 2008-01-11 2010-10-21 노파르티스 아게 키나제 억제제로서의 피리미딘
US20110105510A1 (en) * 2008-06-17 2011-05-05 Hiroshi Ishikawa Prophylactic/ameliorating or therapeutic agent for non-alcoholic steatohepatitis
WO2010036380A1 (en) 2008-09-26 2010-04-01 Intellikine, Inc. Heterocyclic kinase inhibitors
WO2010059836A1 (en) * 2008-11-20 2010-05-27 Decode Genetics Ehf Substituted aza-bridged bicyclics for cardiovascular and cns disease
CN107233337A (zh) 2009-04-29 2017-10-10 阿马里纳药物爱尔兰有限公司 含有epa和心血管剂的药物组合物以及使用其的方法
CA3092541A1 (en) * 2010-04-23 2011-10-27 Steam Tech, Llc Surface wiper system
KR20130083389A (ko) * 2010-05-28 2013-07-22 바이오크리스트파마슈티컬즈,인코포레이티드 야누스 키나아제 억제제로서 헤테로사이클릭 화합물
EP2615089B1 (de) 2010-09-07 2016-04-27 Astellas Pharma Inc. Pyrazolochinolinverbindungen
UY33597A (es) 2010-09-09 2012-04-30 Irm Llc Compuestos y composiciones como inhibidores de la trk
WO2012034095A1 (en) 2010-09-09 2012-03-15 Irm Llc Compounds and compositions as trk inhibitors
AR083878A1 (es) 2010-11-15 2013-03-27 Boehringer Ingelheim Int Terapia antidiabetica vasoprotectora y cardioprotectora, linagliptina, metodo de tratamiento
KR20140014184A (ko) 2011-02-25 2014-02-05 아이알엠 엘엘씨 Trk 억제제로서의 화합물 및 조성물
JP5988941B2 (ja) * 2012-09-20 2016-09-07 富士フイルム株式会社 有機銅錯体、有機銅錯体溶液、銅酸化物薄膜、銅酸化物薄膜の製造方法、および、化合物
US10434132B2 (en) * 2013-06-04 2019-10-08 Academia Sinica Galactolipids-enriched plant extracts and the uses thereof
EP3824906A1 (de) 2016-12-21 2021-05-26 Amgen Inc. Anti-tnf alpha antikörperformulierungen
TWI695839B (zh) * 2017-11-17 2020-06-11 中央研究院 雙（羥甲基）吡咯并酞嗪混成物、其之製備方法與用途
MX2021000293A (es) 2018-07-09 2021-07-15 Boehringer Ingelheim Animal Health Usa Inc Compuestos heterociclicos antihelminticos.
MX2021004471A (es) * 2018-10-17 2021-08-24 Suven Life Sciences Ltd Derivados de pirrolo-pididazina como moduladores alostéricos positivos del receptor muscarínico m1.
BR112021018631A2 (pt) 2019-03-19 2021-11-23 Boehringer Ingelheim Animal Health Usa Inc Compostos anti-helmínticos de aza-benzotiofeno e aza-benzofurano
WO2021242581A1 (en) 2020-05-29 2021-12-02 Boehringer Ingelheim Animal Health USA Inc. Anthelmintic heterocyclic compounds
UY39995A (es) 2021-11-01 2023-05-15 Boehringer Ingelheim Vetmedica GmbH Compuestos de pirrolopiridazina como antihelmínticos
WO2025214612A1 (en) 2023-04-14 2025-10-16 Syngenta Crop Protection Ag Pesticidally-active 2,2-dihalocyclopropyl compounds
WO2025261608A1 (en) 2023-06-29 2025-12-26 Syngenta Crop Protection Ag Pesticidally-active 2,2-dihalocyclopropyl compounds
WO2026019979A1 (en) * 2024-07-19 2026-01-22 Merck Sharp & Dohme Llc Pyrrolopyridazine vegfr tyrosine kinase inhibitors

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1991018903A1 (en) * 1990-05-25 1991-12-12 Fujisawa Pharmaceutical Co., Ltd. Pyrrolopyridazine compounds
DE4224165A1 (de) * 1992-07-22 1994-01-27 Bayer Ag Imidazolinyl-pyrrolo-pyridazine
CZ283216B6 (cs) * 1994-01-19 1998-02-18 Sankyo, Company Limited Pyrrolopyridazinové deriváty
US6472389B1 (en) 1998-05-21 2002-10-29 Shionogi & Co., Ltd. Pyrrolo[1,2-b] pyridazine derivatives having sPLA2 inhibitory effect
IT1303272B1 (it) * 1998-10-29 2000-11-06 Zambon Spa Derivati triciclici inibitori della fosfodiesterasi 4
FR2792938B1 (fr) * 1999-04-28 2001-07-06 Warner Lambert Co NOUVELLES 1-AMINO TRIAZOLO [4,3-a] QUINAZOLINE-5-ONES INHIBITRICES DE PHOSPHODIESTERASES IV
JP2003525291A (ja) * 2000-03-01 2003-08-26 ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ ２，４−二置換チアゾリル誘導体
JPWO2002000621A1 (ja) * 2000-06-29 2004-04-22 塩野義製薬株式会社 Ｘ型ｓＰＬＡ２阻害作用を有する化合物
DK1363910T3 (da) * 2000-11-17 2006-06-26 Bristol Myers Squibb Co Fremgangsmåder til behandling af P39-kinase-associerede tilstande og pyrrolotriazinforbindelser, der er anvendelige som kinase-inhibitorer
TWI312347B (en) * 2001-02-08 2009-07-21 Eisai R&D Man Co Ltd Bicyclic nitrogen-containing condensed ring compounds
CA2458131A1 (en) * 2001-08-23 2003-03-06 Takeda Chemical Industries, Ltd. Jnk activation inhibitor
US6900208B2 (en) * 2002-03-28 2005-05-31 Bristol Myers Squibb Company Pyrrolopyridazine compounds and methods of use thereof for the treatment of proliferative disorders
KR101026819B1 (ko) 2003-01-09 2011-04-04 아스테라스 세이야쿠 가부시키가이샤 피롤로피리다진 유도체

Also Published As

Publication number Publication date
RU2328499C2 (ru) 2008-07-10
EP1581535B3 (de) 2009-09-02
IL169500A0 (en) 2007-07-04
EP1581535A1 (de) 2005-10-05
JP4671104B2 (ja) 2011-04-13
US20050075342A1 (en) 2005-04-07
KR101026819B1 (ko) 2011-04-04
DK1581535T3 (da) 2008-02-11
TW200418861A (en) 2004-10-01
CA2513081A1 (en) 2004-07-29
WO2004063197A1 (en) 2004-07-29
EP1581535B9 (de) 2008-03-19
TWI332004B (en) 2010-10-21
BR0317358A (pt) 2005-12-13
JP2006515597A (ja) 2006-06-01
DE60317102D1 (de) 2007-12-06
HK1088900A1 (zh) 2006-11-17
CA2513081C (en) 2011-04-19
ES2291729T7 (es) 2010-03-31
KR20050092738A (ko) 2005-09-22
DE60317102T2 (de) 2009-01-29
AR042833A1 (es) 2005-07-06
ATE376549T1 (de) 2007-11-15
US7317009B2 (en) 2008-01-08
PL378245A1 (pl) 2006-03-20
NO20053748D0 (no) 2005-08-04
US7153854B2 (en) 2006-12-26
PT1581535E (pt) 2007-12-12
ES2291729T3 (es) 2008-03-01
NZ541232A (en) 2008-02-29
MXPA05007462A (es) 2006-01-27
DE60317102T3 (de) 2010-02-18
US20060270678A1 (en) 2006-11-30
DK1581535T5 (da) 2009-12-21
CY1107084T1 (el) 2012-10-24
EP1581535B1 (de) 2007-10-24
RU2005125209A (ru) 2006-01-27

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