ATE376549T1 - Pyrrolopyridazin derivate - Google Patents
Pyrrolopyridazin derivateInfo
- Publication number
- ATE376549T1 ATE376549T1 AT03789642T AT03789642T ATE376549T1 AT E376549 T1 ATE376549 T1 AT E376549T1 AT 03789642 T AT03789642 T AT 03789642T AT 03789642 T AT03789642 T AT 03789642T AT E376549 T1 ATE376549 T1 AT E376549T1
- Authority
- AT
- Austria
- Prior art keywords
- pyrrolopyridazine derivatives
- pyrrolopyridazine
- derivatives
- Prior art date
Links
- YTJAMOLQXDNLJC-UHFFFAOYSA-N N1N=CC=C2N=CC=C21 Chemical class N1N=CC=C2N=CC=C21 YTJAMOLQXDNLJC-UHFFFAOYSA-N 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pulmonology (AREA)
- Communicable Diseases (AREA)
- Neurosurgery (AREA)
- Oncology (AREA)
- Dermatology (AREA)
- Biomedical Technology (AREA)
- Immunology (AREA)
- Neurology (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Gastroenterology & Hepatology (AREA)
- Virology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AU2003900189A AU2003900189A0 (en) | 2003-01-09 | 2003-01-09 | Heterocyclic derivatives |
| AU2003903628A AU2003903628A0 (en) | 2003-07-14 | 2003-07-14 | Pyrrolopyridazine derivatives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE376549T1 true ATE376549T1 (de) | 2007-11-15 |
Family
ID=32714072
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT03789642T ATE376549T1 (de) | 2003-01-09 | 2003-12-26 | Pyrrolopyridazin derivate |
Country Status (21)
| Country | Link |
|---|---|
| US (2) | US7153854B2 (de) |
| EP (1) | EP1581535B3 (de) |
| JP (1) | JP4671104B2 (de) |
| KR (1) | KR101026819B1 (de) |
| AR (1) | AR042833A1 (de) |
| AT (1) | ATE376549T1 (de) |
| BR (1) | BR0317358A (de) |
| CA (1) | CA2513081C (de) |
| CY (1) | CY1107084T1 (de) |
| DE (1) | DE60317102T3 (de) |
| DK (1) | DK1581535T5 (de) |
| ES (1) | ES2291729T7 (de) |
| IL (1) | IL169500A0 (de) |
| MX (1) | MXPA05007462A (de) |
| NO (1) | NO20053748L (de) |
| NZ (1) | NZ541232A (de) |
| PL (1) | PL378245A1 (de) |
| PT (1) | PT1581535E (de) |
| RU (1) | RU2328499C2 (de) |
| TW (1) | TWI332004B (de) |
| WO (1) | WO2004063197A1 (de) |
Families Citing this family (34)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR101026819B1 (ko) | 2003-01-09 | 2011-04-04 | 아스테라스 세이야쿠 가부시키가이샤 | 피롤로피리다진 유도체 |
| US7030112B2 (en) * | 2003-03-25 | 2006-04-18 | Bristol-Myers Squibb Company | Pyrrolopyridazine compounds and methods of use thereof for the treatment of proliferative disorders |
| GB0411056D0 (en) | 2004-05-18 | 2004-06-23 | Novartis Ag | Organic compounds |
| WO2006004191A1 (en) * | 2004-07-05 | 2006-01-12 | Astellas Pharma Inc. | Pyrrolopyridazine derivatives which inhibit pde iv and tnf alfa |
| ES2319797T3 (es) * | 2004-07-05 | 2009-05-12 | Astellas Pharma Inc. | Derivados de pirazolopiridina. |
| GB0422057D0 (en) * | 2004-10-05 | 2004-11-03 | Astrazeneca Ab | Novel compounds |
| GB0601951D0 (en) | 2006-01-31 | 2006-03-15 | Novartis Ag | Organic compounds |
| JP2010508315A (ja) | 2006-10-30 | 2010-03-18 | ノバルティス アーゲー | 抗炎症剤としてのヘテロ環式化合物 |
| JP2009114123A (ja) * | 2007-11-06 | 2009-05-28 | Astellas Pharma Inc | ２−アシル−１−アミノピロール化合物の新規製造法 |
| AU2008326309C1 (en) * | 2007-11-21 | 2015-03-12 | Decode Genetics Ehf | Biaryl PDE4 inhibitors for treating pulmonary and cardiovascular disorders |
| KR20100113557A (ko) | 2008-01-11 | 2010-10-21 | 노파르티스 아게 | 키나제 억제제로서의 피리미딘 |
| US20110105510A1 (en) * | 2008-06-17 | 2011-05-05 | Hiroshi Ishikawa | Prophylactic/ameliorating or therapeutic agent for non-alcoholic steatohepatitis |
| WO2010036380A1 (en) | 2008-09-26 | 2010-04-01 | Intellikine, Inc. | Heterocyclic kinase inhibitors |
| WO2010059836A1 (en) * | 2008-11-20 | 2010-05-27 | Decode Genetics Ehf | Substituted aza-bridged bicyclics for cardiovascular and cns disease |
| CN107233337A (zh) | 2009-04-29 | 2017-10-10 | 阿马里纳药物爱尔兰有限公司 | 含有epa和心血管剂的药物组合物以及使用其的方法 |
| CA3092541A1 (en) * | 2010-04-23 | 2011-10-27 | Steam Tech, Llc | Surface wiper system |
| KR20130083389A (ko) * | 2010-05-28 | 2013-07-22 | 바이오크리스트파마슈티컬즈,인코포레이티드 | 야누스 키나아제 억제제로서 헤테로사이클릭 화합물 |
| EP2615089B1 (de) | 2010-09-07 | 2016-04-27 | Astellas Pharma Inc. | Pyrazolochinolinverbindungen |
| UY33597A (es) | 2010-09-09 | 2012-04-30 | Irm Llc | Compuestos y composiciones como inhibidores de la trk |
| WO2012034095A1 (en) | 2010-09-09 | 2012-03-15 | Irm Llc | Compounds and compositions as trk inhibitors |
| AR083878A1 (es) | 2010-11-15 | 2013-03-27 | Boehringer Ingelheim Int | Terapia antidiabetica vasoprotectora y cardioprotectora, linagliptina, metodo de tratamiento |
| KR20140014184A (ko) | 2011-02-25 | 2014-02-05 | 아이알엠 엘엘씨 | Trk 억제제로서의 화합물 및 조성물 |
| JP5988941B2 (ja) * | 2012-09-20 | 2016-09-07 | 富士フイルム株式会社 | 有機銅錯体、有機銅錯体溶液、銅酸化物薄膜、銅酸化物薄膜の製造方法、および、化合物 |
| US10434132B2 (en) * | 2013-06-04 | 2019-10-08 | Academia Sinica | Galactolipids-enriched plant extracts and the uses thereof |
| EP3824906A1 (de) | 2016-12-21 | 2021-05-26 | Amgen Inc. | Anti-tnf alpha antikörperformulierungen |
| TWI695839B (zh) * | 2017-11-17 | 2020-06-11 | 中央研究院 | 雙（羥甲基）吡咯并酞嗪混成物、其之製備方法與用途 |
| MX2021000293A (es) | 2018-07-09 | 2021-07-15 | Boehringer Ingelheim Animal Health Usa Inc | Compuestos heterociclicos antihelminticos. |
| MX2021004471A (es) * | 2018-10-17 | 2021-08-24 | Suven Life Sciences Ltd | Derivados de pirrolo-pididazina como moduladores alostéricos positivos del receptor muscarínico m1. |
| BR112021018631A2 (pt) | 2019-03-19 | 2021-11-23 | Boehringer Ingelheim Animal Health Usa Inc | Compostos anti-helmínticos de aza-benzotiofeno e aza-benzofurano |
| WO2021242581A1 (en) | 2020-05-29 | 2021-12-02 | Boehringer Ingelheim Animal Health USA Inc. | Anthelmintic heterocyclic compounds |
| UY39995A (es) | 2021-11-01 | 2023-05-15 | Boehringer Ingelheim Vetmedica GmbH | Compuestos de pirrolopiridazina como antihelmínticos |
| WO2025214612A1 (en) | 2023-04-14 | 2025-10-16 | Syngenta Crop Protection Ag | Pesticidally-active 2,2-dihalocyclopropyl compounds |
| WO2025261608A1 (en) | 2023-06-29 | 2025-12-26 | Syngenta Crop Protection Ag | Pesticidally-active 2,2-dihalocyclopropyl compounds |
| WO2026019979A1 (en) * | 2024-07-19 | 2026-01-22 | Merck Sharp & Dohme Llc | Pyrrolopyridazine vegfr tyrosine kinase inhibitors |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1991018903A1 (en) * | 1990-05-25 | 1991-12-12 | Fujisawa Pharmaceutical Co., Ltd. | Pyrrolopyridazine compounds |
| DE4224165A1 (de) * | 1992-07-22 | 1994-01-27 | Bayer Ag | Imidazolinyl-pyrrolo-pyridazine |
| CZ283216B6 (cs) * | 1994-01-19 | 1998-02-18 | Sankyo, Company Limited | Pyrrolopyridazinové deriváty |
| US6472389B1 (en) | 1998-05-21 | 2002-10-29 | Shionogi & Co., Ltd. | Pyrrolo[1,2-b] pyridazine derivatives having sPLA2 inhibitory effect |
| IT1303272B1 (it) * | 1998-10-29 | 2000-11-06 | Zambon Spa | Derivati triciclici inibitori della fosfodiesterasi 4 |
| FR2792938B1 (fr) * | 1999-04-28 | 2001-07-06 | Warner Lambert Co | NOUVELLES 1-AMINO TRIAZOLO [4,3-a] QUINAZOLINE-5-ONES INHIBITRICES DE PHOSPHODIESTERASES IV |
| JP2003525291A (ja) * | 2000-03-01 | 2003-08-26 | ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ | ２，４−二置換チアゾリル誘導体 |
| JPWO2002000621A1 (ja) * | 2000-06-29 | 2004-04-22 | 塩野義製薬株式会社 | Ｘ型ｓＰＬＡ２阻害作用を有する化合物 |
| DK1363910T3 (da) * | 2000-11-17 | 2006-06-26 | Bristol Myers Squibb Co | Fremgangsmåder til behandling af P39-kinase-associerede tilstande og pyrrolotriazinforbindelser, der er anvendelige som kinase-inhibitorer |
| TWI312347B (en) * | 2001-02-08 | 2009-07-21 | Eisai R&D Man Co Ltd | Bicyclic nitrogen-containing condensed ring compounds |
| CA2458131A1 (en) * | 2001-08-23 | 2003-03-06 | Takeda Chemical Industries, Ltd. | Jnk activation inhibitor |
| US6900208B2 (en) * | 2002-03-28 | 2005-05-31 | Bristol Myers Squibb Company | Pyrrolopyridazine compounds and methods of use thereof for the treatment of proliferative disorders |
| KR101026819B1 (ko) | 2003-01-09 | 2011-04-04 | 아스테라스 세이야쿠 가부시키가이샤 | 피롤로피리다진 유도체 |
-
2003
- 2003-12-26 KR KR1020057012805A patent/KR101026819B1/ko not_active Expired - Fee Related
- 2003-12-26 PT PT03789642T patent/PT1581535E/pt unknown
- 2003-12-26 MX MXPA05007462A patent/MXPA05007462A/es active IP Right Grant
- 2003-12-26 WO PCT/JP2003/017091 patent/WO2004063197A1/en not_active Ceased
- 2003-12-26 RU RU2005125209/04A patent/RU2328499C2/ru not_active IP Right Cessation
- 2003-12-26 DE DE60317102T patent/DE60317102T3/de not_active Expired - Lifetime
- 2003-12-26 CA CA2513081A patent/CA2513081C/en not_active Expired - Fee Related
- 2003-12-26 JP JP2004566309A patent/JP4671104B2/ja not_active Expired - Fee Related
- 2003-12-26 BR BR0317358-5A patent/BR0317358A/pt not_active IP Right Cessation
- 2003-12-26 AT AT03789642T patent/ATE376549T1/de active
- 2003-12-26 DK DK03789642T patent/DK1581535T5/da active
- 2003-12-26 EP EP03789642A patent/EP1581535B3/de not_active Expired - Lifetime
- 2003-12-26 ES ES03789642T patent/ES2291729T7/es active Active
- 2003-12-26 PL PL378245A patent/PL378245A1/pl unknown
- 2003-12-26 NZ NZ541232A patent/NZ541232A/en not_active IP Right Cessation
- 2003-12-30 US US10/747,079 patent/US7153854B2/en not_active Expired - Fee Related
-
2004
- 2004-01-08 TW TW093100400A patent/TWI332004B/zh active
- 2004-01-09 AR ARP040100063A patent/AR042833A1/es unknown
-
2005
- 2005-07-03 IL IL169500A patent/IL169500A0/en unknown
- 2005-08-04 NO NO20053748A patent/NO20053748L/no unknown
-
2006
- 2006-08-08 US US11/500,293 patent/US7317009B2/en not_active Expired - Fee Related
-
2007
- 2007-12-12 CY CY20071101578T patent/CY1107084T1/el unknown
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