ATE376549T1 - Pyrrolopyridazin derivate - Google Patents
Pyrrolopyridazin derivateInfo
- Publication number
- ATE376549T1 ATE376549T1 AT03789642T AT03789642T ATE376549T1 AT E376549 T1 ATE376549 T1 AT E376549T1 AT 03789642 T AT03789642 T AT 03789642T AT 03789642 T AT03789642 T AT 03789642T AT E376549 T1 ATE376549 T1 AT E376549T1
- Authority
- AT
- Austria
- Prior art keywords
- pyrrolopyridazine derivatives
- pyrrolopyridazine
- derivatives
- Prior art date
Links
- YTJAMOLQXDNLJC-UHFFFAOYSA-N N1N=CC=C2N=CC=C21 Chemical class N1N=CC=C2N=CC=C21 YTJAMOLQXDNLJC-UHFFFAOYSA-N 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pulmonology (AREA)
- Neurosurgery (AREA)
- Immunology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Biomedical Technology (AREA)
- Dermatology (AREA)
- Neurology (AREA)
- Virology (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Gastroenterology & Hepatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AU2003900189A AU2003900189A0 (en) | 2003-01-09 | 2003-01-09 | Heterocyclic derivatives |
| AU2003903628A AU2003903628A0 (en) | 2003-07-14 | 2003-07-14 | Pyrrolopyridazine derivatives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE376549T1 true ATE376549T1 (de) | 2007-11-15 |
Family
ID=32714072
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT03789642T ATE376549T1 (de) | 2003-01-09 | 2003-12-26 | Pyrrolopyridazin derivate |
Country Status (21)
| Country | Link |
|---|---|
| US (2) | US7153854B2 (de) |
| EP (1) | EP1581535B3 (de) |
| JP (1) | JP4671104B2 (de) |
| KR (1) | KR101026819B1 (de) |
| AR (1) | AR042833A1 (de) |
| AT (1) | ATE376549T1 (de) |
| BR (1) | BR0317358A (de) |
| CA (1) | CA2513081C (de) |
| CY (1) | CY1107084T1 (de) |
| DE (1) | DE60317102T3 (de) |
| DK (1) | DK1581535T5 (de) |
| ES (1) | ES2291729T7 (de) |
| IL (1) | IL169500A0 (de) |
| MX (1) | MXPA05007462A (de) |
| NO (1) | NO20053748L (de) |
| NZ (1) | NZ541232A (de) |
| PL (1) | PL378245A1 (de) |
| PT (1) | PT1581535E (de) |
| RU (1) | RU2328499C2 (de) |
| TW (1) | TWI332004B (de) |
| WO (1) | WO2004063197A1 (de) |
Families Citing this family (34)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK1581535T5 (da) | 2003-01-09 | 2009-12-21 | Astellas Pharma Inc | Pyrrolopyridazinderivater |
| US7030112B2 (en) * | 2003-03-25 | 2006-04-18 | Bristol-Myers Squibb Company | Pyrrolopyridazine compounds and methods of use thereof for the treatment of proliferative disorders |
| GB0411056D0 (en) | 2004-05-18 | 2004-06-23 | Novartis Ag | Organic compounds |
| WO2006004191A1 (en) * | 2004-07-05 | 2006-01-12 | Astellas Pharma Inc. | Pyrrolopyridazine derivatives which inhibit pde iv and tnf alfa |
| DE602005011286D1 (en) * | 2004-07-05 | 2009-01-08 | Astellas Pharma Inc | Pyrazolopyridinderivate |
| GB0422057D0 (en) * | 2004-10-05 | 2004-11-03 | Astrazeneca Ab | Novel compounds |
| GB0601951D0 (en) | 2006-01-31 | 2006-03-15 | Novartis Ag | Organic compounds |
| JP2010508315A (ja) | 2006-10-30 | 2010-03-18 | ノバルティス アーゲー | 抗炎症剤としてのヘテロ環式化合物 |
| JP2009114123A (ja) * | 2007-11-06 | 2009-05-28 | Astellas Pharma Inc | ２−アシル−１−アミノピロール化合物の新規製造法 |
| JP2011504505A (ja) * | 2007-11-21 | 2011-02-10 | デコード ジェネティクス イーエイチエフ | 肺および心血管障害を治療するためのビアリールｐｄｅ４抑制剤 |
| AU2009203693B2 (en) | 2008-01-11 | 2012-06-07 | Novartis Ag | Pyrimidines as kinase inhibitors |
| US20110105510A1 (en) * | 2008-06-17 | 2011-05-05 | Hiroshi Ishikawa | Prophylactic/ameliorating or therapeutic agent for non-alcoholic steatohepatitis |
| CA2738429C (en) * | 2008-09-26 | 2016-10-25 | Intellikine, Inc. | Heterocyclic kinase inhibitors |
| WO2010059836A1 (en) * | 2008-11-20 | 2010-05-27 | Decode Genetics Ehf | Substituted aza-bridged bicyclics for cardiovascular and cns disease |
| SG175390A1 (en) | 2009-04-29 | 2011-12-29 | Amarin Corp Plc | Pharmaceutical compositions comprising epa and a cardiovascular agent and methods of using the same |
| KR101849417B1 (ko) * | 2010-04-23 | 2018-04-16 | 스팀 테크, 엘엘씨 | 표면 와이퍼 시스템 |
| MX2012013824A (es) * | 2010-05-28 | 2013-03-12 | Biocryst Pharm Inc | Compuestos heterociclicos como inhibidores de cinasa janus. |
| RS54834B1 (sr) | 2010-09-07 | 2016-10-31 | Astellas Pharma Inc | Jedinjenja pirazolokvinolina |
| UY33597A (es) | 2010-09-09 | 2012-04-30 | Irm Llc | Compuestos y composiciones como inhibidores de la trk |
| WO2012034095A1 (en) | 2010-09-09 | 2012-03-15 | Irm Llc | Compounds and compositions as trk inhibitors |
| AR083878A1 (es) | 2010-11-15 | 2013-03-27 | Boehringer Ingelheim Int | Terapia antidiabetica vasoprotectora y cardioprotectora, linagliptina, metodo de tratamiento |
| MA34969B1 (fr) | 2011-02-25 | 2014-03-01 | Irm Llc | Composes et compositions en tant qu inibiteurs de trk |
| JP5988941B2 (ja) * | 2012-09-20 | 2016-09-07 | 富士フイルム株式会社 | 有機銅錯体、有機銅錯体溶液、銅酸化物薄膜、銅酸化物薄膜の製造方法、および、化合物 |
| US10434132B2 (en) * | 2013-06-04 | 2019-10-08 | Academia Sinica | Galactolipids-enriched plant extracts and the uses thereof |
| WO2018119142A1 (en) | 2016-12-21 | 2018-06-28 | Amgen Inc. | Anti-tnf alpha antibody formulations |
| EP3710005B8 (de) * | 2017-11-17 | 2023-06-14 | Academia Sinica | SUBSTITUIERTE PYRROLO[2,1,-ALPHA]PHTHALAZINE- UND BENZO[g]PYRROL[2,1,-ALPHA]PHTHALAZINEDERIVATE UND IHRE VERWENDUNG ZUR BEHANDLUNG VON KREBS |
| US12269822B2 (en) | 2018-07-09 | 2025-04-08 | Boehringer Ingelheim Animal Health USA Inc. | Anthelminthic heterocyclic compounds |
| EA202191046A1 (ru) * | 2018-10-17 | 2021-07-12 | Сувен Лайф Сайенсиз Лимитед | Производные пирролопиридазина, как позитивные аллостерические модуляторы мускаринового рецептора m1 |
| MX2021011302A (es) | 2019-03-19 | 2022-01-19 | Boehringer Ingelheim Animal Health Usa Inc | Compuestos de aza-benzotiofeno y aza-benzofurano como antihelminticos. |
| KR20230028268A (ko) | 2020-05-29 | 2023-02-28 | 뵈링거 잉겔하임 애니멀 헬스 유에스에이 인코포레이티드 | 구충성 헤테로시클릭 화합물 |
| US11999742B2 (en) | 2021-11-01 | 2024-06-04 | Boehringer Ingelheim Vetmedica Gmbh | Substituted pyrrolo[1,2-b]pyridazines as anthelmintics |
| WO2025214612A1 (en) | 2023-04-14 | 2025-10-16 | Syngenta Crop Protection Ag | Pesticidally-active 2,2-dihalocyclopropyl compounds |
| WO2025261608A1 (en) | 2023-06-29 | 2025-12-26 | Syngenta Crop Protection Ag | Pesticidally-active 2,2-dihalocyclopropyl compounds |
| WO2026019979A1 (en) * | 2024-07-19 | 2026-01-22 | Merck Sharp & Dohme Llc | Pyrrolopyridazine vegfr tyrosine kinase inhibitors |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH06501918A (ja) * | 1990-05-25 | 1994-03-03 | 藤沢薬品工業株式会社 | ピロロピリダジン化合物 |
| DE4224165A1 (de) * | 1992-07-22 | 1994-01-27 | Bayer Ag | Imidazolinyl-pyrrolo-pyridazine |
| ATE229020T1 (de) * | 1994-01-19 | 2002-12-15 | Sankyo Co | Pyrrolopyridazin-derivate |
| CN1302300A (zh) | 1998-05-21 | 2001-07-04 | 盐野义制药株式会社 | 吡咯并[1,2－b]哒嗪sPLA2抑制剂 |
| IT1303272B1 (it) * | 1998-10-29 | 2000-11-06 | Zambon Spa | Derivati triciclici inibitori della fosfodiesterasi 4 |
| FR2792938B1 (fr) * | 1999-04-28 | 2001-07-06 | Warner Lambert Co | NOUVELLES 1-AMINO TRIAZOLO [4,3-a] QUINAZOLINE-5-ONES INHIBITRICES DE PHOSPHODIESTERASES IV |
| JP2003525291A (ja) * | 2000-03-01 | 2003-08-26 | ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ | ２，４−二置換チアゾリル誘導体 |
| AU2001267823A1 (en) * | 2000-06-29 | 2002-01-08 | Shionogi And Co., Ltd. | Compounds exhibiting x-type spla2 inhibiting effect |
| GEP20063915B (en) * | 2000-11-17 | 2006-09-11 | Bristol Myers Squibb Co | PYRROLOTRIAZINE COMPOUNDS USEFUL AS KINASE INHIBITORS AND USE THEREOF FOR TREATING p38 KINASE-ASSOCIATED CONDITIONS |
| TWI312347B (en) * | 2001-02-08 | 2009-07-21 | Eisai R&D Man Co Ltd | Bicyclic nitrogen-containing condensed ring compounds |
| WO2003018020A1 (en) * | 2001-08-23 | 2003-03-06 | Takeda Chemical Industries, Ltd. | Jnk inhibitors |
| US6900208B2 (en) * | 2002-03-28 | 2005-05-31 | Bristol Myers Squibb Company | Pyrrolopyridazine compounds and methods of use thereof for the treatment of proliferative disorders |
| DK1581535T5 (da) | 2003-01-09 | 2009-12-21 | Astellas Pharma Inc | Pyrrolopyridazinderivater |
-
2003
- 2003-12-26 DK DK03789642T patent/DK1581535T5/da active
- 2003-12-26 BR BR0317358-5A patent/BR0317358A/pt not_active IP Right Cessation
- 2003-12-26 DE DE60317102T patent/DE60317102T3/de not_active Expired - Lifetime
- 2003-12-26 PL PL378245A patent/PL378245A1/pl unknown
- 2003-12-26 KR KR1020057012805A patent/KR101026819B1/ko not_active Expired - Fee Related
- 2003-12-26 MX MXPA05007462A patent/MXPA05007462A/es active IP Right Grant
- 2003-12-26 EP EP03789642A patent/EP1581535B3/de not_active Expired - Lifetime
- 2003-12-26 PT PT03789642T patent/PT1581535E/pt unknown
- 2003-12-26 RU RU2005125209/04A patent/RU2328499C2/ru not_active IP Right Cessation
- 2003-12-26 AT AT03789642T patent/ATE376549T1/de active
- 2003-12-26 CA CA2513081A patent/CA2513081C/en not_active Expired - Fee Related
- 2003-12-26 WO PCT/JP2003/017091 patent/WO2004063197A1/en not_active Ceased
- 2003-12-26 JP JP2004566309A patent/JP4671104B2/ja not_active Expired - Fee Related
- 2003-12-26 NZ NZ541232A patent/NZ541232A/en not_active IP Right Cessation
- 2003-12-26 ES ES03789642T patent/ES2291729T7/es active Active
- 2003-12-30 US US10/747,079 patent/US7153854B2/en not_active Expired - Fee Related
-
2004
- 2004-01-08 TW TW093100400A patent/TWI332004B/zh active
- 2004-01-09 AR ARP040100063A patent/AR042833A1/es unknown
-
2005
- 2005-07-03 IL IL169500A patent/IL169500A0/en unknown
- 2005-08-04 NO NO20053748A patent/NO20053748L/no unknown
-
2006
- 2006-08-08 US US11/500,293 patent/US7317009B2/en not_active Expired - Fee Related
-
2007
- 2007-12-12 CY CY20071101578T patent/CY1107084T1/el unknown
Also Published As
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| IS8045A (is) | Púrín-6-ón-afleiður | |
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