ATE376549T1 - Pyrrolopyridazin derivate - Google Patents
Pyrrolopyridazin derivateInfo
- Publication number
- ATE376549T1 ATE376549T1 AT03789642T AT03789642T ATE376549T1 AT E376549 T1 ATE376549 T1 AT E376549T1 AT 03789642 T AT03789642 T AT 03789642T AT 03789642 T AT03789642 T AT 03789642T AT E376549 T1 ATE376549 T1 AT E376549T1
- Authority
- AT
- Austria
- Prior art keywords
- pyrrolopyridazine derivatives
- pyrrolopyridazine
- derivatives
- Prior art date
Links
- YTJAMOLQXDNLJC-UHFFFAOYSA-N N1N=CC=C2N=CC=C21 Chemical class N1N=CC=C2N=CC=C21 YTJAMOLQXDNLJC-UHFFFAOYSA-N 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pulmonology (AREA)
- Neurosurgery (AREA)
- Immunology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Biomedical Technology (AREA)
- Dermatology (AREA)
- Neurology (AREA)
- Virology (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Gastroenterology & Hepatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AU2003900189A AU2003900189A0 (en) | 2003-01-09 | 2003-01-09 | Heterocyclic derivatives |
| AU2003903628A AU2003903628A0 (en) | 2003-07-14 | 2003-07-14 | Pyrrolopyridazine derivatives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE376549T1 true ATE376549T1 (de) | 2007-11-15 |
Family
ID=32714072
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT03789642T ATE376549T1 (de) | 2003-01-09 | 2003-12-26 | Pyrrolopyridazin derivate |
Country Status (21)
| Country | Link |
|---|---|
| US (2) | US7153854B2 (de) |
| EP (1) | EP1581535B3 (de) |
| JP (1) | JP4671104B2 (de) |
| KR (1) | KR101026819B1 (de) |
| AR (1) | AR042833A1 (de) |
| AT (1) | ATE376549T1 (de) |
| BR (1) | BR0317358A (de) |
| CA (1) | CA2513081C (de) |
| CY (1) | CY1107084T1 (de) |
| DE (1) | DE60317102T3 (de) |
| DK (1) | DK1581535T5 (de) |
| ES (1) | ES2291729T7 (de) |
| IL (1) | IL169500A0 (de) |
| MX (1) | MXPA05007462A (de) |
| NO (1) | NO20053748L (de) |
| NZ (1) | NZ541232A (de) |
| PL (1) | PL378245A1 (de) |
| PT (1) | PT1581535E (de) |
| RU (1) | RU2328499C2 (de) |
| TW (1) | TWI332004B (de) |
| WO (1) | WO2004063197A1 (de) |
Families Citing this family (35)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ541232A (en) | 2003-01-09 | 2008-02-29 | Astellas Pharma Inc | Pyrrolopyridazine derivatives |
| US7030112B2 (en) * | 2003-03-25 | 2006-04-18 | Bristol-Myers Squibb Company | Pyrrolopyridazine compounds and methods of use thereof for the treatment of proliferative disorders |
| GB0411056D0 (en) | 2004-05-18 | 2004-06-23 | Novartis Ag | Organic compounds |
| JP5092402B2 (ja) * | 2004-07-05 | 2012-12-05 | アステラス製薬株式会社 | ピラゾロピリジン誘導体 |
| WO2006004191A1 (en) * | 2004-07-05 | 2006-01-12 | Astellas Pharma Inc. | Pyrrolopyridazine derivatives which inhibit pde iv and tnf alfa |
| GB0422057D0 (en) * | 2004-10-05 | 2004-11-03 | Astrazeneca Ab | Novel compounds |
| GB0601951D0 (en) | 2006-01-31 | 2006-03-15 | Novartis Ag | Organic compounds |
| KR20090075714A (ko) | 2006-10-30 | 2009-07-08 | 노파르티스 아게 | 소염제로서의 헤테로시클릭 화합물 |
| JP2009114123A (ja) * | 2007-11-06 | 2009-05-28 | Astellas Pharma Inc | ２−アシル−１−アミノピロール化合物の新規製造法 |
| EP2674417A3 (de) * | 2007-11-21 | 2014-04-09 | Decode Genetics EHF | Biaryl-PDE4-Inhibitoren zur Behandlung von Entzündungen |
| EP2231642B1 (de) | 2008-01-11 | 2013-10-23 | Novartis AG | Pyrimidine als kinasehemmer |
| WO2009154230A1 (ja) * | 2008-06-17 | 2009-12-23 | 持田製薬株式会社 | 非アルコール性脂肪肝炎の予防／改善・治療薬 |
| JP5731978B2 (ja) * | 2008-09-26 | 2015-06-10 | インテリカイン， エルエルシー | 複素環キナーゼ阻害剤 |
| WO2010059836A1 (en) * | 2008-11-20 | 2010-05-27 | Decode Genetics Ehf | Substituted aza-bridged bicyclics for cardiovascular and cns disease |
| NZ720946A (en) | 2009-04-29 | 2017-09-29 | Amarin Pharmaceuticals Ie Ltd | Pharmaceutical compositions comprising epa and a cardiovascular agent and methods of using the same |
| US9387831B2 (en) * | 2010-04-23 | 2016-07-12 | Steam Tech, Llc | Surface wiper system |
| CA2799926A1 (en) * | 2010-05-28 | 2011-12-01 | Biocryst Pharmaceuticals, Inc. | Heterocyclic compounds as janus kinase inhibitors |
| HRP20160473T1 (hr) | 2010-09-07 | 2016-07-29 | Astellas Pharma Inc. | Pirazolokinolinski spojevi |
| WO2012034095A1 (en) | 2010-09-09 | 2012-03-15 | Irm Llc | Compounds and compositions as trk inhibitors |
| US8637516B2 (en) | 2010-09-09 | 2014-01-28 | Irm Llc | Compounds and compositions as TRK inhibitors |
| AR083878A1 (es) | 2010-11-15 | 2013-03-27 | Boehringer Ingelheim Int | Terapia antidiabetica vasoprotectora y cardioprotectora, linagliptina, metodo de tratamiento |
| AU2012220572A1 (en) | 2011-02-25 | 2013-08-29 | Irm Llc | Compounds and compositions as trk inhibitors |
| JP5988941B2 (ja) * | 2012-09-20 | 2016-09-07 | 富士フイルム株式会社 | 有機銅錯体、有機銅錯体溶液、銅酸化物薄膜、銅酸化物薄膜の製造方法、および、化合物 |
| US10434132B2 (en) * | 2013-06-04 | 2019-10-08 | Academia Sinica | Galactolipids-enriched plant extracts and the uses thereof |
| US20200087390A1 (en) | 2016-12-21 | 2020-03-19 | Amgen Inc. | Anti-tnf alpha antibody formulations |
| EP3710005B8 (de) * | 2017-11-17 | 2023-06-14 | Academia Sinica | SUBSTITUIERTE PYRROLO[2,1,-ALPHA]PHTHALAZINE- UND BENZO[g]PYRROL[2,1,-ALPHA]PHTHALAZINEDERIVATE UND IHRE VERWENDUNG ZUR BEHANDLUNG VON KREBS |
| MX2021000293A (es) | 2018-07-09 | 2021-07-15 | Boehringer Ingelheim Animal Health Usa Inc | Compuestos heterociclicos antihelminticos. |
| MA53917A (fr) * | 2018-10-17 | 2022-01-26 | Suven Life Sciences Ltd | Dérivés de pyrrolo-pyridazine en tant que modulateurs allostériques positifs du récepteur m1 muscarinique |
| JP7637630B2 (ja) | 2019-03-19 | 2025-02-28 | ベーリンガー インゲルハイム フェトメディカ ゲーエムベーハー | 駆虫性アザベンゾチオフェンおよびアザベンゾフラン化合物 |
| PH12022553222A1 (en) | 2020-05-29 | 2024-02-12 | Boehringer Ingelheim Animal Health Usa Inc | Anthelmintic heterocyclic compounds |
| IL300628A (en) | 2020-09-10 | 2023-04-01 | Vanda Pharmaceuticals Inc | Methods for the treatment of cyclic diseases or conditions-PDE IV |
| AR127495A1 (es) | 2021-11-01 | 2024-01-31 | Boehringer Ingelheim Vetmedica Gmbh | Compuestos de pirrolopiridazina como antihelmínticos |
| WO2025214612A1 (en) | 2023-04-14 | 2025-10-16 | Syngenta Crop Protection Ag | Pesticidally-active 2,2-dihalocyclopropyl compounds |
| WO2025261608A1 (en) | 2023-06-29 | 2025-12-26 | Syngenta Crop Protection Ag | Pesticidally-active 2,2-dihalocyclopropyl compounds |
| WO2026019979A1 (en) * | 2024-07-19 | 2026-01-22 | Merck Sharp & Dohme Llc | Pyrrolopyridazine vegfr tyrosine kinase inhibitors |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1991018903A1 (en) * | 1990-05-25 | 1991-12-12 | Fujisawa Pharmaceutical Co., Ltd. | Pyrrolopyridazine compounds |
| DE4224165A1 (de) * | 1992-07-22 | 1994-01-27 | Bayer Ag | Imidazolinyl-pyrrolo-pyridazine |
| DE69529056T2 (de) * | 1994-01-19 | 2003-11-13 | Sankyo Co., Ltd. | Pyrrolopyridazin-derivate |
| KR20010034881A (ko) * | 1998-05-21 | 2001-04-25 | 시오노 요시히코 | ｓＰＬＡ2 억제 효과를 갖는 피롤로[1,2-ｂ]피리다진 유도체 |
| IT1303272B1 (it) * | 1998-10-29 | 2000-11-06 | Zambon Spa | Derivati triciclici inibitori della fosfodiesterasi 4 |
| FR2792938B1 (fr) * | 1999-04-28 | 2001-07-06 | Warner Lambert Co | NOUVELLES 1-AMINO TRIAZOLO [4,3-a] QUINAZOLINE-5-ONES INHIBITRICES DE PHOSPHODIESTERASES IV |
| ATE414079T1 (de) * | 2000-03-01 | 2008-11-15 | Janssen Pharmaceutica Nv | 2,4-disubstituierte thiazolyl derivate |
| JPWO2002000621A1 (ja) * | 2000-06-29 | 2004-04-22 | 塩野義製薬株式会社 | Ｘ型ｓＰＬＡ２阻害作用を有する化合物 |
| KR100847605B1 (ko) * | 2000-11-17 | 2008-07-21 | 브리스톨-마이어스스퀴브컴파니 | ｐ38 키나제 관련 질병의 치료 방법 및 키나제 억제제로서유용한 피롤로트리아진 화합물 |
| TWI312347B (en) * | 2001-02-08 | 2009-07-21 | Eisai R&D Man Co Ltd | Bicyclic nitrogen-containing condensed ring compounds |
| CA2458131A1 (en) * | 2001-08-23 | 2003-03-06 | Takeda Chemical Industries, Ltd. | Jnk activation inhibitor |
| US6900208B2 (en) * | 2002-03-28 | 2005-05-31 | Bristol Myers Squibb Company | Pyrrolopyridazine compounds and methods of use thereof for the treatment of proliferative disorders |
| NZ541232A (en) | 2003-01-09 | 2008-02-29 | Astellas Pharma Inc | Pyrrolopyridazine derivatives |
-
2003
- 2003-12-26 NZ NZ541232A patent/NZ541232A/en not_active IP Right Cessation
- 2003-12-26 PL PL378245A patent/PL378245A1/pl unknown
- 2003-12-26 JP JP2004566309A patent/JP4671104B2/ja not_active Expired - Fee Related
- 2003-12-26 BR BR0317358-5A patent/BR0317358A/pt not_active IP Right Cessation
- 2003-12-26 EP EP03789642A patent/EP1581535B3/de not_active Expired - Lifetime
- 2003-12-26 CA CA2513081A patent/CA2513081C/en not_active Expired - Fee Related
- 2003-12-26 DE DE60317102T patent/DE60317102T3/de not_active Expired - Lifetime
- 2003-12-26 RU RU2005125209/04A patent/RU2328499C2/ru not_active IP Right Cessation
- 2003-12-26 ES ES03789642T patent/ES2291729T7/es active Active
- 2003-12-26 WO PCT/JP2003/017091 patent/WO2004063197A1/en not_active Ceased
- 2003-12-26 KR KR1020057012805A patent/KR101026819B1/ko not_active Expired - Fee Related
- 2003-12-26 AT AT03789642T patent/ATE376549T1/de active
- 2003-12-26 PT PT03789642T patent/PT1581535E/pt unknown
- 2003-12-26 DK DK03789642T patent/DK1581535T5/da active
- 2003-12-26 MX MXPA05007462A patent/MXPA05007462A/es active IP Right Grant
- 2003-12-30 US US10/747,079 patent/US7153854B2/en not_active Expired - Fee Related
-
2004
- 2004-01-08 TW TW093100400A patent/TWI332004B/zh active
- 2004-01-09 AR ARP040100063A patent/AR042833A1/es unknown
-
2005
- 2005-07-03 IL IL169500A patent/IL169500A0/en unknown
- 2005-08-04 NO NO20053748A patent/NO20053748L/no unknown
-
2006
- 2006-08-08 US US11/500,293 patent/US7317009B2/en not_active Expired - Fee Related
-
2007
- 2007-12-12 CY CY20071101578T patent/CY1107084T1/el unknown
Also Published As
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