NO20053796L - Process for the production of particles - Google Patents

Process for the production of particles

Info

Publication number
NO20053796L
NO20053796L NO20053796A NO20053796A NO20053796L NO 20053796 L NO20053796 L NO 20053796L NO 20053796 A NO20053796 A NO 20053796A NO 20053796 A NO20053796 A NO 20053796A NO 20053796 L NO20053796 L NO 20053796L
Authority
NO
Norway
Prior art keywords
substance
solvent
particles
forming
solution
Prior art date
Application number
NO20053796A
Other languages
English (en)
Norwegian (no)
Other versions
NO20053796D0 (no
Inventor
Robert Price
Joerg Sebastian Kaerger
Original Assignee
Univ Bath
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=32910470&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NO20053796(L) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from GB0304037A external-priority patent/GB0304037D0/en
Priority claimed from GB0313129A external-priority patent/GB0313129D0/en
Application filed by Univ Bath filed Critical Univ Bath
Publication of NO20053796D0 publication Critical patent/NO20053796D0/no
Publication of NO20053796L publication Critical patent/NO20053796L/no

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1688—Processes resulting in pure drug agglomerate optionally containing up to 5% of excipient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D9/00—Crystallisation
    • B01D9/0018—Evaporation of components of the mixture to be separated
    • B01D9/0027—Evaporation of components of the mixture to be separated by means of conveying fluid, e.g. spray-crystallisation
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D9/00—Crystallisation
    • B01D9/005—Selection of auxiliary, e.g. for control of crystallisation nuclei, of crystal growth, of adherence to walls; Arrangements for introduction thereof
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D9/00—Crystallisation
    • B01D9/0081—Use of vibrations, e.g. ultrasound
    • C—CHEMISTRY; METALLURGY
    • C30—CRYSTAL GROWTH
    • C30B—SINGLE-CRYSTAL GROWTH; UNIDIRECTIONAL SOLIDIFICATION OF EUTECTIC MATERIAL OR UNIDIRECTIONAL DEMIXING OF EUTECTOID MATERIAL; REFINING BY ZONE-MELTING OF MATERIAL; PRODUCTION OF A HOMOGENEOUS POLYCRYSTALLINE MATERIAL WITH DEFINED STRUCTURE; SINGLE CRYSTALS OR HOMOGENEOUS POLYCRYSTALLINE MATERIAL WITH DEFINED STRUCTURE; AFTER-TREATMENT OF SINGLE CRYSTALS OR A HOMOGENEOUS POLYCRYSTALLINE MATERIAL WITH DEFINED STRUCTURE; APPARATUS THEREFOR
    • C30B29/00—Single crystals or homogeneous polycrystalline material with defined structure characterised by the material or by their shape
    • C30B29/54—Organic compounds
    • C—CHEMISTRY; METALLURGY
    • C30—CRYSTAL GROWTH
    • C30B—SINGLE-CRYSTAL GROWTH; UNIDIRECTIONAL SOLIDIFICATION OF EUTECTIC MATERIAL OR UNIDIRECTIONAL DEMIXING OF EUTECTOID MATERIAL; REFINING BY ZONE-MELTING OF MATERIAL; PRODUCTION OF A HOMOGENEOUS POLYCRYSTALLINE MATERIAL WITH DEFINED STRUCTURE; SINGLE CRYSTALS OR HOMOGENEOUS POLYCRYSTALLINE MATERIAL WITH DEFINED STRUCTURE; AFTER-TREATMENT OF SINGLE CRYSTALS OR A HOMOGENEOUS POLYCRYSTALLINE MATERIAL WITH DEFINED STRUCTURE; APPARATUS THEREFOR
    • C30B7/00—Single-crystal growth from solutions using solvents which are liquid at normal temperature, e.g. aqueous solutions

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Pulmonology (AREA)
  • Materials Engineering (AREA)
  • Metallurgy (AREA)
  • Otolaryngology (AREA)
  • Emergency Medicine (AREA)
  • Pain & Pain Management (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
NO20053796A 2003-02-21 2005-08-11 Process for the production of particles NO20053796L (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB0304037A GB0304037D0 (en) 2003-02-21 2003-02-21 Process for the production of particles for use in pharmaceutical formulations
GB0313129A GB0313129D0 (en) 2003-06-06 2003-06-06 Process for the production of particles
PCT/GB2004/000654 WO2004073827A1 (en) 2003-02-21 2004-02-19 Process for the production of particles

Publications (2)

Publication Number Publication Date
NO20053796D0 NO20053796D0 (no) 2005-08-11
NO20053796L true NO20053796L (no) 2005-11-03

Family

ID=32910470

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20053796A NO20053796L (no) 2003-02-21 2005-08-11 Process for the production of particles

Country Status (11)

Country Link
US (2) US20070065372A1 (pl)
EP (1) EP1610878B1 (pl)
JP (1) JP5154078B2 (pl)
CA (1) CA2516733C (pl)
DK (1) DK1610878T3 (pl)
ES (1) ES2520841T3 (pl)
NO (1) NO20053796L (pl)
PL (1) PL224720B1 (pl)
PT (1) PT1610878E (pl)
SI (1) SI1610878T1 (pl)
WO (1) WO2004073827A1 (pl)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2579725A1 (en) * 2004-09-14 2006-03-23 Ada S. Cowan Highly-aqueous non-respirable aerosols containing biologically-active ingredients method of making and device therefor
AU2006275319B2 (en) 2005-08-04 2012-09-13 Saban Ventures Pty Limited Space disinfection
GB0525852D0 (en) * 2005-12-20 2006-02-01 Accentus Plc Crystallisation apparatus and process
FR2897281B1 (fr) * 2006-02-14 2009-01-23 Saint Louis Inst Procede de fabrication par nanocristallisation de composes energetiques ou inertes
JP4597107B2 (ja) * 2006-03-02 2010-12-15 三井金属鉱業株式会社 砒素含有体からの砒素除去方法及び砒素除去装置
GB0610090D0 (en) * 2006-05-20 2006-06-28 Price Robert Particulate drug compositions and their uses
CA2677100C (en) 2007-02-02 2018-03-27 Saban Ventures Pty Limited Membrane vapour concentrator
GB0705159D0 (en) * 2007-03-19 2007-04-25 Prosonix Ltd Process for making crystals
ES2310131B1 (es) * 2007-06-04 2009-12-04 INSTITUTO NACIONAL DE TECNICA AEROESPACIAL "ESTEBAN TERRADAS" Procedimiento de cristalizacion a partir de solucion.
GB0711680D0 (en) * 2007-06-18 2007-07-25 Prosonix Ltd Process
GB0806873D0 (en) * 2008-04-16 2008-05-21 Breath Ltd Steroid nebuliser formulation
CN102149437B (zh) * 2008-07-18 2017-02-15 普罗索尼克斯有限公司 用于提高氟替卡松颗粒结晶度的方法
WO2010097188A1 (en) 2009-02-25 2010-09-02 Chiesi Farmaceutici S.P.A. Inhalation particles comprising a salt of carmoterol and a corticosteroid
GB0914240D0 (en) 2009-08-14 2009-09-30 Breath Ltd Steroid solvates
GB0914231D0 (en) * 2009-08-14 2009-09-30 Breath Ltd Dry powder inhaler formulations
GB0918431D0 (en) 2009-10-21 2009-12-09 Prosonix Ltd Process for improving crystallinity
RU2585101C2 (ru) 2010-04-01 2016-05-27 КЬЕЗИ ФАРМАЧЕУТИЧИ С.п.А. Способ приготовления частиц носителя для сухих порошков для ингаляции
EP2500072A1 (en) 2011-03-15 2012-09-19 LEK Pharmaceuticals d.d. A novel process of residual solvent removal
CN102166504B (zh) * 2011-03-22 2013-03-06 中国人民解放军第三0九医院 一种凝胶微球快速成型装置及方法
CN102350280B (zh) * 2011-06-23 2013-06-05 中国人民解放军第三0九医院 具有超声波振动装置的静电液滴发生装置及应用其制备载药凝胶微球的方法
US9643996B2 (en) 2011-11-04 2017-05-09 Battelle Memorial Institute Processes for producing protein microparticles
CN107880091B (zh) 2012-05-08 2020-12-18 尼科斯眼药公司 疏水性治疗剂的制剂、其制备方法及应用
US8765725B2 (en) 2012-05-08 2014-07-01 Aciex Therapeutics, Inc. Preparations of hydrophobic therapeutic agents, methods of manufacture and use thereof
US9815865B2 (en) 2013-01-07 2017-11-14 Nicox Ophthalmics, Inc. Preparations of hydrophobic therapeutic agents, methods of manufacture and use thereof
CN104721052A (zh) * 2015-02-10 2015-06-24 武汉工程大学 一种纳米药物制备装置
GB2551944B (en) * 2015-12-18 2021-09-01 Midatech Pharma Wales Ltd Microparticle production process and apparatus
US10583085B2 (en) 2017-05-17 2020-03-10 Chiesi Farmaceutici S.P.A. Carrier particles for dry powder formulations for inhalation
KR102092068B1 (ko) * 2018-03-26 2020-03-23 중앙대학교 산학협력단 약물 결정의 제조를 위한 비용매를 이용한 결정화 장치 및 이를 이용한 약물 결정의 제조 방법
PL3829641T3 (pl) 2018-07-27 2024-09-30 Chiesi Farmaceutici S.P.A. Nowe cząstki nośnikowe do preparatów suchego proszku do inhalacji

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK0432232T3 (da) * 1989-05-01 1994-01-31 Alkermes Inc Fremgangsmåde til fremstilling af små partikler af biologisk aktive molekyler
US5376386A (en) * 1990-01-24 1994-12-27 British Technology Group Limited Aerosol carriers
GB9105705D0 (en) * 1991-03-18 1991-05-01 Sandoz Ltd Improvements in or relating to organic compounds
US5993805A (en) * 1991-04-10 1999-11-30 Quadrant Healthcare (Uk) Limited Spray-dried microparticles and their use as therapeutic vehicles
GB9501841D0 (en) * 1995-01-31 1995-03-22 Co Ordinated Drug Dev Improvements in and relating to carrier particles for use in dry powder inhalers
SE9501384D0 (sv) * 1995-04-13 1995-04-13 Astra Ab Process for the preparation of respirable particles
US5874029A (en) * 1996-10-09 1999-02-23 The University Of Kansas Methods for particle micronization and nanonization by recrystallization from organic solutions sprayed into a compressed antisolvent
DE19617085A1 (de) * 1996-04-29 1997-10-30 Bayer Ag Verfahren zur Herstellung von feinstteiligen Kristallisationsprodukten
JP3447042B2 (ja) * 1997-07-23 2003-09-16 フロイント産業株式会社 単一物質球形粒の製造方法
GB9828721D0 (en) * 1998-12-24 1999-02-17 Glaxo Group Ltd Novel apparatus and process
US6522582B1 (en) * 1999-03-05 2003-02-18 Xilinx, Inc. Non-volatile memory array using gate breakdown structures
JP3490015B2 (ja) * 1999-03-11 2004-01-26 関西ティー・エル・オー株式会社 化学的耐久性に優れた放射性微小球及びその製造方法
FR2797875B1 (fr) * 1999-08-26 2001-10-19 Hoechst Marion Roussel Inc Agglomerats spheriques de telithromycine, leur procede de preparation et leur application dans la preparation de formes pharmaceutiques
GB9925934D0 (en) * 1999-11-03 1999-12-29 Glaxo Group Ltd Novel apparatus and process
CH694686A5 (it) * 2000-03-04 2005-06-15 Eco2 Sa Prodotto di micronizzazione di sostanze farmaceutiche.
GB0008411D0 (en) * 2000-04-05 2000-05-24 Vectura Ltd Pharmaceutical preparations and their manufacture
AU2001254995A1 (en) * 2000-05-15 2001-11-26 Vectura Limited Method of manufacturing particles
CN1250312C (zh) * 2001-05-05 2006-04-12 阿山特斯有限公司 小晶体形成
EP1539319A4 (en) * 2002-04-29 2005-10-12 Bristol Myers Squibb Co CRYSTALLIZATION SYSTEM USING ATOMIZATION
GB0219815D0 (en) * 2002-08-24 2002-10-02 Accentus Plc Preparation of small crystals

Also Published As

Publication number Publication date
ES2520841T3 (es) 2014-11-11
US20170143632A1 (en) 2017-05-25
JP2006519780A (ja) 2006-08-31
EP1610878B1 (en) 2014-09-03
PL378127A1 (pl) 2006-03-06
NO20053796D0 (no) 2005-08-11
CA2516733C (en) 2011-09-27
EP1610878A1 (en) 2006-01-04
US20070065372A1 (en) 2007-03-22
PL224720B1 (pl) 2017-01-31
PT1610878E (pt) 2014-12-03
JP5154078B2 (ja) 2013-02-27
WO2004073827A1 (en) 2004-09-02
SI1610878T1 (sl) 2015-02-27
DK1610878T3 (da) 2014-12-01
CA2516733A1 (en) 2004-09-02

Similar Documents

Publication Publication Date Title
ES2520841T3 (es) Procedimiento para la producción de partículas
AU2003291973A1 (en) A self-cleaning spray nozzle
WO2004033298A3 (en) Method and apparatus for using a unit dose dispenser
WO2007041090A3 (en) Receptacles and kits, such as for dry powder packaging
NO20001747L (no) Doseringsform for aerosoladministrasjon
SE0200920D0 (sv) Novel compounds
ATE538777T1 (de) Vardenafil hydrochlorid trihydrat enthaltende arzneimittel und deren herstellungsverfahren
NO20061674L (no) Sterilisering ved hoyt trykk for avsluttende sterilisering av farmasoytiske preparater og medisinske produkter
WO2007015003A3 (fr) Nouvelle forme cristalline iii de l'agomelatine, son procede de preparation et les compositions pharmaceutiques qui la contiennent
WO2001098245A3 (en) Triphenyl compounds as interleukin-4 antagonists
MXPA02012889A (es) Esteres de acidos 4-alcoxi-ciclohexano-1-amino-carboxilicos y procedimiento para su obtencion.
EP1223172A3 (de) Verfahren zur Herstellung von reinem Triethylendiamin (TEDA)
JP2007502170A5 (pl)
AU2002348829A1 (en) Novel compounds and their use in medicine, process for their preparation and pharmaceutical compositions containing them
Ross et al. Continuous manufacture and scale-up of theophylline-nicotinamide cocrystals
WO2006059103A3 (en) Pyridine based compounds useful as intermediates for pharmaceutical or agricultural end-products
NO20062824L (no) 1,3-Difenylprop-2-en-1-on-avledete forbindelser, fremgangsmater for fremstilling derav, samt anvendelse av samme
ITMI20010428A1 (it) Composizioni ad uso inalatorio a base di formoterolo
De Sousa et al. Synthesis and antidepressant evaluation of three para-benzoquinone mono-oximes and their oxy derivatives
WO2023122200A3 (en) Modular industrial unit for pharmaceutical productions
WO2006097556A3 (es) Nueva formulación estable de aerosoles en suspensión y procedimiento de obtención
JP2008514600A5 (ja) 医薬用エアロゾル製品及びその製造方法
BRPI0505593A (pt) processo de fabricação de um pó contendo partìculas cristalinas de glucopiranosil-alditóis
Chang et al. Reduction in the residues of penthiopyrad in processed edible vegetables by various soaking treatments and health hazard evaluation in China
EP1036797A1 (en) Crystalline anthracycline antibiotic and process for producing the same

Legal Events

Date Code Title Description
FC2A Withdrawal, rejection or dismissal of laid open patent application