NO20053809L - Diarylmetylindenpiperidinderivater,fremgangsmate for fremstilling derav, og anvendelse derav - Google Patents

Diarylmetylindenpiperidinderivater,fremgangsmate for fremstilling derav, og anvendelse derav

Info

Publication number: NO20053809L
Authority: NO; Norway
Prior art keywords: diarylmethylindenepiperidine; derivatives; preparation; compounds; enantiomers
Prior art date: 2003-01-16

Application number

NO20053809A

Other languages

English (en)

Norwegian (no)

Other versions

NO20053809D0 (no

Inventor

William Brown

Christopher Walpole

Andrew Griffin

Original Assignee

Astrazeneca Ab

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2003-01-16

Filing date

2005-08-12

Publication date

2005-10-17

2005-08-12 Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab

2005-08-12 Publication of NO20053809D0 publication Critical patent/NO20053809D0/no

2005-10-17 Publication of NO20053809L publication Critical patent/NO20053809L/no

Links

238000000034 method Methods 0.000 title abstract 2
150000001875 compounds Chemical class 0.000 abstract 3
HBAQYPYDRFILMT-UHFFFAOYSA-N 8-[3-(1-cyclopropylpyrazol-4-yl)-1H-pyrazolo[4,3-d]pyrimidin-5-yl]-3-methyl-3,8-diazabicyclo[3.2.1]octan-2-one Chemical class C1(CC1)N1N=CC(=C1)C1=NNC2=C1N=C(N=C2)N1C2C(N(CC1CC2)C)=O HBAQYPYDRFILMT-UHFFFAOYSA-N 0.000 abstract 1
239000008194 pharmaceutical composition Substances 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
238000002560 therapeutic procedure Methods 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D211/70—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/10—Laxatives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/12—Antidiarrhoeals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/14—Antitussive agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/32—Alcohol-abuse
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/34—Tobacco-abuse
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/36—Opioid-abuse
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/12—Antidiuretics, e.g. drugs for diabetes insipidus
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Animal Behavior & Ethology (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmacology & Pharmacy (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Addiction (AREA)
Immunology (AREA)
Psychiatry (AREA)
Pain & Pain Management (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Pulmonology (AREA)
Diabetes (AREA)
Reproductive Health (AREA)
Rheumatology (AREA)
Hematology (AREA)
Gynecology & Obstetrics (AREA)
Psychology (AREA)
Oncology (AREA)
Urology & Nephrology (AREA)
Virology (AREA)
Transplantation (AREA)
Orthopedic Medicine & Surgery (AREA)
Physical Education & Sports Medicine (AREA)
Communicable Diseases (AREA)
Pregnancy & Childbirth (AREA)
Vascular Medicine (AREA)

NO20053809A 2003-01-16 2005-08-12 Diarylmetylindenpiperidinderivater,fremgangsmate for fremstilling derav, og anvendelse derav NO20053809L (no)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
SE0300105A SE0300105D0 (sv)	2003-01-16	2003-01-16	Diarylmethylidene piperdine derivatives, preparations thereof and uses thereof
PCT/GB2004/000099 WO2004062562A2 (en)	2003-01-16	2004-01-13	Diarylmethylidene piperidine derivatives, preparations thereof and uses thereof

Publications (2)

Publication Number	Publication Date
NO20053809D0 NO20053809D0 (no)	2005-08-12
NO20053809L true NO20053809L (no)	2005-10-17

Family

ID=20290140

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO20053809A NO20053809L (no)	2003-01-16	2005-08-12	Diarylmetylindenpiperidinderivater,fremgangsmate for fremstilling derav, og anvendelse derav

Country Status (21)

Country	Link
US (1)	US20060154964A1 (is)
EP (1)	EP1587790A2 (is)
JP (1)	JP2006516559A (is)
KR (1)	KR20050096137A (is)
CN (1)	CN100422151C (is)
AR (1)	AR042887A1 (is)
AU (1)	AU2004204390B2 (is)
BR (1)	BRPI0406614A (is)
CA (1)	CA2510382A1 (is)
IL (1)	IL169366A0 (is)
IS (1)	IS7980A (is)
MX (1)	MXPA05007484A (is)
NO (1)	NO20053809L (is)
NZ (1)	NZ540758A (is)
PL (1)	PL378336A1 (is)
RU (1)	RU2324680C2 (is)
SE (1)	SE0300105D0 (is)
TW (1)	TW200504059A (is)
UA (1)	UA80012C2 (is)
WO (1)	WO2004062562A2 (is)
ZA (1)	ZA200505186B (is)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DK1395567T3 (da)	2001-05-18	2009-04-06	Astrazeneca Ab	4-(phenylpiperazinylmethyl)-benzamidderivater og deres anvendelse til behandling af smerte, angst eller mavetarmslidelser
SE0203301D0 (sv) *	2002-11-07	2002-11-07	Astrazeneca Ab	Novel Compounds
SE0203303D0 (sv)	2002-11-07	2002-11-07	Astrazeneca Ab	Novel Compounds
SE0203300D0 (sv)	2002-11-07	2002-11-07	Astrazeneca Ab	Novel Compounds
BRPI0410347A (pt) *	2003-05-16	2006-05-30	Astrazeneca Ab	composto, uso de um composto, composição farmacêutica, métodos para as terapias da dor e de distúrbios gostrointestinais funcionais em animal de sangue quente, e, processo para preparação de um composto
CN101921279A (zh)	2003-10-01	2010-12-22	阿得罗公司	螺环杂环衍生物及其应用方法
DK1781631T3 (da)	2004-08-02	2012-05-14	Astrazeneca Ab	Diarylmethylpiperazinderivater, præparater dermed og anvendelser deraf
CN101128447A (zh) *	2005-02-28	2008-02-20	阿斯利康(瑞典)有限公司	二芳基甲基哌嗪衍生物，其制备及其用途
US7598261B2 (en)	2005-03-31	2009-10-06	Adolor Corporation	Spirocyclic heterocyclic derivatives and methods of their use
US7576207B2 (en)	2006-04-06	2009-08-18	Adolor Corporation	Spirocyclic heterocyclic derivatives and methods of their use
MY148880A (en) *	2006-10-20	2013-06-14	Astrazeneca Ab	N-(2-hydroxyethyl)-n-methyl-4-(quinolin-8-yl(1-(thiazol-4-ylmethyl)piperidin-4-ylidene)methyl)benzamide, the process of making it as well as its use for the treatment of pain, anxiety and depression
EP3233825B1 (en) *	2014-12-19	2020-04-29	Pharmnovo AB	Diarylmethylidene piperidine derivatives and their use as delta opioid receptor agonists
CN111825654A (zh) *	2019-04-19	2020-10-27	北京酷瓴生物技术有限公司	苯甲烯哌啶衍生物及其制备方法、中间体和用途

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US2898339A (en) *	1957-07-29	1959-08-04	Wm S Merrell Co	N-substituted benzhydrol, benzhydryl, and benzhydrylidene piperidine
US4581171A (en) *	1983-07-27	1986-04-08	Janssen Pharmaceutica, N.V.	[[Bis(aryl)methylene]-1-piperidinyl]alkyl-pyrimidinones useful for treating psychotropic disorders
US4816586A (en) *	1987-07-29	1989-03-28	Regents Of The University Of Minnesota	Delta opioid receptor antagonists
US5140029A (en) *	1989-01-09	1992-08-18	Janssen Pharmaceutica N.V.	2-aminopyrimidinone derivatives
US4939137A (en) *	1989-06-28	1990-07-03	Ortho Pharmaceutical Corporation	Ring-fused thienopyrimidinedione derivatives
US5683998A (en) *	1991-04-23	1997-11-04	Toray Industries, Inc.	Tricyclic triazolo derivatives, processes for producing the same and the uses of the same
US5574159A (en) *	1992-02-03	1996-11-12	Delta Pharmaceuticals, Inc.	Opioid compounds and methods for making therefor
ZA979781B (en) *	1996-11-14	1998-06-08	Akzo Nobel Nv	Piperidine derivatives.
TW548271B (en) *	1996-12-20	2003-08-21	Astra Pharma Inc	Novel piperidine derivatives having an exocyclic double bond with analgesic effects
EP1263758A2 (en) *	2000-03-03	2002-12-11	Ortho-McNeil Pharmaceutical, Inc.	3-(diarylmethylene)-8-azabicyclo[3.2.1]octane derivatives
US6556387B1 (en) *	2000-03-31	2003-04-29	Seagate Technology Llc	Controlling mechanical response characteristics of a disc drive actuator by adjusting a fastener engaging the actuator shaft to vary axial force on the bearing assembly
SE0001207D0 (sv) *	2000-04-04	2000-04-04	Astrazeneca Canada Inc	Novel compounds
SE0101766D0 (sv) *	2001-05-18	2001-05-18	Astrazeneca Ab	Novel compounds
US7589103B2 (en) *	2003-06-27	2009-09-15	Janssen Pharmaceutica N.V.	Tricyclic-bridged piperidinylidene derivatives as 8-opioid modulators

2003
- 2003-01-16 SE SE0300105A patent/SE0300105D0/xx unknown
2004
- 2004-01-13 JP JP2006500202A patent/JP2006516559A/ja not_active Abandoned
- 2004-01-13 KR KR1020057013174A patent/KR20050096137A/ko not_active Withdrawn
- 2004-01-13 MX MXPA05007484A patent/MXPA05007484A/es not_active Application Discontinuation
- 2004-01-13 UA UAA200506380A patent/UA80012C2/uk unknown
- 2004-01-13 AU AU2004204390A patent/AU2004204390B2/en not_active Ceased
- 2004-01-13 CA CA002510382A patent/CA2510382A1/en not_active Abandoned
- 2004-01-13 RU RU2005121491/04A patent/RU2324680C2/ru not_active IP Right Cessation
- 2004-01-13 US US10/541,522 patent/US20060154964A1/en not_active Abandoned
- 2004-01-13 CN CNB2004800022753A patent/CN100422151C/zh not_active Expired - Fee Related
- 2004-01-13 NZ NZ540758A patent/NZ540758A/en unknown
- 2004-01-13 PL PL378336A patent/PL378336A1/pl not_active Application Discontinuation
- 2004-01-13 WO PCT/GB2004/000099 patent/WO2004062562A2/en not_active Ceased
- 2004-01-13 EP EP04701624A patent/EP1587790A2/en not_active Withdrawn
- 2004-01-13 BR BR0406614-6A patent/BRPI0406614A/pt not_active IP Right Cessation
- 2004-01-14 TW TW093100912A patent/TW200504059A/zh unknown
- 2004-01-15 AR ARP040100105A patent/AR042887A1/es not_active Application Discontinuation
2005
- 2005-06-23 IL IL169366A patent/IL169366A0/en unknown
- 2005-06-27 ZA ZA200505186A patent/ZA200505186B/en unknown
- 2005-08-12 NO NO20053809A patent/NO20053809L/no not_active Application Discontinuation
- 2005-08-12 IS IS7980A patent/IS7980A/is unknown

Also Published As

Publication number	Publication date
RU2005121491A (ru)	2006-02-10
AU2004204390A1 (en)	2004-07-29
AR042887A1 (es)	2005-07-06
RU2324680C2 (ru)	2008-05-20
CN1738801A (zh)	2006-02-22
BRPI0406614A (pt)	2005-12-06
TW200504059A (en)	2005-02-01
NO20053809D0 (no)	2005-08-12
AU2004204390B2 (en)	2007-09-06
WO2004062562A2 (en)	2004-07-29
SE0300105D0 (sv)	2003-01-16
KR20050096137A (ko)	2005-10-05
ZA200505186B (en)	2006-04-26
IL169366A0 (en)	2007-07-04
EP1587790A2 (en)	2005-10-26
JP2006516559A (ja)	2006-07-06
IS7980A (is)	2005-08-12
PL378336A1 (pl)	2006-03-20
US20060154964A1 (en)	2006-07-13
CN100422151C (zh)	2008-10-01
NZ540758A (en)	2008-03-28
WO2004062562A3 (en)	2004-09-16
UA80012C2 (en)	2007-08-10
MXPA05007484A (es)	2005-09-21
CA2510382A1 (en)	2004-07-29

Legal Events

Date	Code	Title	Description
2009-08-31	FC2A	Withdrawal, rejection or dismissal of laid open patent application

Publication	Publication Date	Title
GB0305152D0 (en)	2003-04-09	Organic compounds
TNSN06064A1 (en)	2007-10-03	5-phenyl-4-methyl-thiazol-2-yl-amine derivatives as inhibitors of phosphatidylinositol 3 kinase enzymes (pi3) for the treatment of inflammatory airway diseases
AU2002314914A1 (en)	2002-12-16	Hydroxy alkyl amine derivatives as beta-secretase inhibitors and their use for the treatment of alzheimer's disease and similar diseases
TW200519106A (en)	2005-06-16	Organic compounds
SE0401971D0 (sv)	2004-08-02	Piperidne derivatives
SE0104140D0 (sv)	2001-12-07	Novel Compounds
MY156407A (en)	2016-02-26	5-phenylthiazole derivatives and use as p13 kinase inhibitors
TW200606162A (en)	2006-02-16	Pyrazolopyridine derivatives
NO20053748L (no)	2005-10-07	Pyrrolopyridazinderivater.
SE0300480D0 (sv)	2003-02-21	Novel compounds
NO20054085L (no)	2005-09-02	Substituerte heksahydropyrazino [1,2-a]pyrimidin-4,7-dionderivater, fremgangsmater for fremstilling og anvendelse derav som medikamenter
NO20072089L (no)	2007-06-15	Benzimidazolderivater, sammensetninger som inneholder dem, fremstilling derav og anvendelse derav
NO20070837L (no)	2007-04-16	Pyrido-pyrido pyrimidinderivater, fremstilling derav samt terapeutisk anvendelse for behandling av cancer.
SE0401970D0 (sv)	2004-08-02	Novel compounds
NO20053809L (no)	2005-10-17	Diarylmetylindenpiperidinderivater,fremgangsmate for fremstilling derav, og anvendelse derav
TW200504029A (en)	2005-02-01	Benzimidazole derivatives, compositions containing them, preparation thereof and uses thereof
WO2004041802A8 (en)	2005-03-10	4(phenyl-piperazinyl-methyl) benzamide derivatives and their use for the treatment of pain or gastrointestinal disorders
MXPA05013050A (es)	2006-03-02	Derivados de bencimidazol, composiciones que los contienen preparacion de los mismos y usos de los mismos.
SE0401763D0 (sv)	2004-07-05	Compounds
NO20052699L (no)	2005-06-06	4(fenylpiperazinyl-metyl)benzamid-derivater og deres anvendelse ved behandling av smerte og gastrointestinale lidelser.
NO20063619L (no)	2006-10-09	Diarylmetylpiperazinderivater, fremstilling og anvendelse derav
NO20053805L (no)	2005-10-17	Diarylmetylindenpiperidinderivater, framgangsmate for fremstilling derav, og anvendelse derav
SE0202693D0 (sv)	2002-09-11	Compounds
ATE440835T1 (de)	2009-09-15	Heterozyklische harnstoff-derivate für die behandlung von schmerzen.
TW200510312A (en)	2005-03-16	Diarylmethylidene piperidine derivatives, preparations thereof and uses thereof