NO20053947L - Forbedrede antitumorale behandlinger. - Google Patents
Forbedrede antitumorale behandlinger.Info
- Publication number
- NO20053947L NO20053947L NO20053947A NO20053947A NO20053947L NO 20053947 L NO20053947 L NO 20053947L NO 20053947 A NO20053947 A NO 20053947A NO 20053947 A NO20053947 A NO 20053947A NO 20053947 L NO20053947 L NO 20053947L
- Authority
- NO
- Norway
- Prior art keywords
- improved antitumoral
- antitumoral treatments
- treatments
- improved
- treatment
- Prior art date
Links
- 238000011282 treatment Methods 0.000 title abstract 3
- 230000000259 anti-tumor effect Effects 0.000 title 1
- UUSZLLQJYRSZIS-LXNNNBEUSA-N plitidepsin Chemical compound CN([C@H](CC(C)C)C(=O)N[C@@H]1C(=O)N[C@@H]([C@H](CC(=O)O[C@H](C(=O)[C@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N2CCC[C@H]2C(=O)N(C)[C@@H](CC=2C=CC(OC)=CC=2)C(=O)O[C@@H]1C)C(C)C)O)[C@@H](C)CC)C(=O)[C@@H]1CCCN1C(=O)C(C)=O UUSZLLQJYRSZIS-LXNNNBEUSA-N 0.000 abstract 2
- 206010025323 Lymphomas Diseases 0.000 abstract 1
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 201000011510 cancer Diseases 0.000 abstract 1
- 238000002648 combination therapy Methods 0.000 abstract 1
- 208000032839 leukemia Diseases 0.000 abstract 1
- 229950008499 plitidepsin Drugs 0.000 abstract 1
- 108010049948 plitidepsin Proteins 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/15—Depsipeptides; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Epidemiology (AREA)
- Physical Education & Sports Medicine (AREA)
- Oncology (AREA)
- Hematology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
Sammendrag Aplidin og aplidinanaloger kan benyttes for behandling av cancer, særlig for behandling av leukemier og lymfomer, og særlig ved kombinasjonsterapi.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US45412503P | 2003-03-12 | 2003-03-12 | |
| PCT/US2004/007606 WO2004080421A2 (en) | 2003-03-12 | 2004-03-12 | Improved antitumoral treatments |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| NO20053947D0 NO20053947D0 (no) | 2005-08-24 |
| NO20053947L true NO20053947L (no) | 2005-12-07 |
Family
ID=32990868
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20053947A NO20053947L (no) | 2003-03-12 | 2005-08-24 | Forbedrede antitumorale behandlinger. |
Country Status (13)
| Country | Link |
|---|---|
| US (2) | US7576188B2 (no) |
| EP (1) | EP1620117A4 (no) |
| JP (1) | JP2006519848A (no) |
| KR (1) | KR20060002778A (no) |
| CN (3) | CN101579520A (no) |
| AU (1) | AU2004220451B2 (no) |
| CA (1) | CA2516572A1 (no) |
| MX (1) | MXPA05009741A (no) |
| NO (1) | NO20053947L (no) |
| NZ (1) | NZ541634A (no) |
| RU (1) | RU2341283C2 (no) |
| UA (2) | UA83022C2 (no) |
| WO (1) | WO2004080421A2 (no) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9803448D0 (en) | 1998-02-18 | 1998-04-15 | Pharma Mar Sa | Pharmaceutical formulation |
| IL149488A0 (en) * | 1999-11-15 | 2002-11-10 | Pharma Mar Sa | Pharmaceutical compositions containing aplidine |
| UA76718C2 (uk) | 2000-06-30 | 2006-09-15 | Фарма Мар, С.А. | Протипухлинні похідні аплідину |
| BR0114604A (pt) | 2000-10-12 | 2003-10-14 | Pharma Mar Sa | Tratamento de cnceres |
| JP4584245B2 (ja) | 2003-03-12 | 2010-11-17 | ダナ−ファーバー キャンサー インスティテュート,インコーポレイテッド | 多発性骨髄腫治療用のアプリジン |
| KR20060002778A (ko) | 2003-03-12 | 2006-01-09 | 파르마 마르, 에스.에이. | 개선된 항종양 치료 |
| HUE028055T2 (en) * | 2006-02-28 | 2016-11-28 | Pharma Mar Sa | Improved treatment of myeloma multiplex |
| ITMI20070817A1 (it) * | 2007-04-19 | 2008-10-20 | Farmacetika Ltd | Composizione farmaceutica comprendente l-carnitina ed un agente antagonista dei recettori adenosinici di membrana, loro derivati e/o sali farmaceuticamente accettabili, e uso degli stessi nella preparazione di farmaci con effetto non tossico di inibi |
| WO2008135793A1 (en) * | 2007-05-04 | 2008-11-13 | Pharma Mar S.A. | Combination of aplidine and carboplatin in anticancer treatments |
| AU2008313627A1 (en) * | 2007-10-19 | 2009-04-23 | Pharma Mar, S.A. | Improved antitumoral treatments |
| CN101965191A (zh) * | 2008-03-07 | 2011-02-02 | 法马马有限公司 | 改善的抗癌治疗 |
| WO2010029158A1 (en) * | 2008-09-12 | 2010-03-18 | Pharma Mar, S.A. | Aplidine in the treatment of chronic myeloproliferative disorders |
| CN104706599B (zh) * | 2013-12-11 | 2020-10-02 | 中国海洋大学 | 一种携带膜海鞘素化合物的冻干粉针剂 |
| SG10201913290QA (en) * | 2016-03-15 | 2020-03-30 | Oryzon Genomics Sa | Combinations of lsd1 inhibitors for the treatment of hematological malignancies |
| LT3615544T (lt) | 2017-04-27 | 2023-05-10 | Pharma Mar S.A. | Priešnavikiniai junginiai |
| KR20260019479A (ko) | 2023-05-04 | 2026-02-10 | 레볼루션 메디슨즈, 인크. | Ras 관련 질환 또는 장애를 위한 병용 요법 |
Family Cites Families (35)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4950649A (en) | 1980-09-12 | 1990-08-21 | University Of Illinois | Didemnins and nordidemnins |
| US4493796A (en) | 1980-09-12 | 1985-01-15 | Board Of Trustees, Univ. Of Ill. | Didemnins A, B, C, and derivatives thereof, as antiviral agents |
| DE3161556D1 (en) | 1980-09-12 | 1984-01-05 | Univ Illinois | Novel antibiotics, derivatives thereof, processes for their extraction, and compositions containing them |
| IT1153974B (it) | 1982-09-23 | 1987-01-21 | Erba Farmitalia | Composizioni farmacologiche a base di cisplatino e metodo per il loro ottenimento |
| ATE74761T1 (de) | 1985-09-20 | 1992-05-15 | Cernitin Sa | Verwendung von pflanzenpollenextrakten zur herstellung von das wachstum von tumorzellen hemmenden pharmazeutischen praeparaten und verfahren zu ihrer herstellung. |
| US4948791A (en) | 1989-04-10 | 1990-08-14 | The Board Of Trustees Of The University Of Illinois | Novel Cytotoxic cyclic depsipeptides from the tunicate trididemnum solidum |
| GB8922026D0 (en) | 1989-09-29 | 1989-11-15 | Pharma Mar Sa | Novel anti-viral and cytotoxic agent |
| US20030148933A1 (en) * | 1990-10-01 | 2003-08-07 | Pharma Mar S.A. | Derivatives of dehydrodidemnin B |
| US5018188A (en) | 1989-12-20 | 1991-05-21 | Motorola, Inc. | Microphone-controller with multifunction, single conductor |
| DE4120327A1 (de) | 1991-06-20 | 1992-12-24 | Basf Ag | Neue peptide, ihre herstellung und verwendung |
| US5482726A (en) * | 1992-07-14 | 1996-01-09 | Us Harvest Technologies Corporation | Method for reducing contamination of shellfish |
| US5580871A (en) | 1992-11-20 | 1996-12-03 | The Dupont Merck Pharmaceutical Company | 4-Heteroaryl- 1,4-dihydropyridine compounds with calcium agonist and alpha1 -antagonist activity |
| US5462726A (en) | 1993-12-17 | 1995-10-31 | Bristol-Myers Squibb Company | Method of inhibiting side effects of solvents containing ricinoleic acid or castor oil or derivatives thereof employing a thromboxane A2 receptor antagonist and pharmaceutical compositions containing such solvents |
| ES2102322B1 (es) | 1995-07-13 | 1998-03-01 | Pharma Mar Sa | Procedimiento de preparacion de didemnina a. |
| US6156724A (en) | 1996-06-07 | 2000-12-05 | Rinehart; Kenneth L. | Uses of didemnins as immunomodulating agents |
| AU3353897A (en) | 1996-07-03 | 1998-02-02 | Mckechnie Uk Limited | Container |
| JP2001504814A (ja) | 1996-10-24 | 2001-04-10 | ザ・ボード・オブ・トラステイーズ・オブ・ザ・ユニバーシテイ・オブ・イリノイ | ジデムニンAのアミノHip類似体の全合成 |
| JP2001503746A (ja) | 1996-10-24 | 2001-03-21 | ザ・ボード・オブ・トラステイーズ・オブ・ザ・ユニバーシテイ・オブ・イリノイ | ジデムニン類似体の半合成法 |
| US6034058A (en) | 1997-04-15 | 2000-03-07 | Rinehart; Kenneth L. | Semi-synthetic alanyl dilemnin analogs |
| WO1998050048A1 (en) * | 1997-05-07 | 1998-11-12 | Pharma Mar, S.A. | Aplidine as an l-type calcium channel enhancer |
| GB9803448D0 (en) | 1998-02-18 | 1998-04-15 | Pharma Mar Sa | Pharmaceutical formulation |
| GB9821975D0 (en) * | 1998-10-08 | 1998-12-02 | Pharma Mar Sa | New cytotoxic alkaloids |
| US6245759B1 (en) * | 1999-03-11 | 2001-06-12 | Merck & Co., Inc. | Tyrosine kinase inhibitors |
| IL149488A0 (en) * | 1999-11-15 | 2002-11-10 | Pharma Mar Sa | Pharmaceutical compositions containing aplidine |
| SE9904175D0 (sv) | 1999-11-18 | 1999-11-18 | Pharmacia & Upjohn Diag Ab | Assay device and use thereof |
| ES2272462T3 (es) | 2000-04-07 | 2007-05-01 | The Trustees Of The University Of Pennsylvania | Analogos de tamadarina y didemnina y procedimiento de fabricacion y uso. |
| AU6836301A (en) * | 2000-06-20 | 2002-01-02 | Idec Pharma Corp | Treatment of b-cell associated diseases such as malignancies and autoimmune diseases using a cold anti-cd20 antibody/radiolabeled anti-cd22 antibody combination |
| UA76718C2 (uk) | 2000-06-30 | 2006-09-15 | Фарма Мар, С.А. | Протипухлинні похідні аплідину |
| WO2002030441A2 (en) | 2000-10-12 | 2002-04-18 | Pharma Mar, S.A. | Treatment of cancers by aplidine in conjunction with a myoprotector |
| BR0114604A (pt) | 2000-10-12 | 2003-10-14 | Pharma Mar Sa | Tratamento de cnceres |
| CA2435418A1 (en) * | 2001-01-24 | 2002-08-01 | Mestex Ag | Use of neurotoxic substances in producing a medicament for treating joint pains |
| ATA13422001A (de) | 2001-08-23 | 2003-09-15 | Plasser Bahnbaumasch Franz | Maschine zur bearbeitung einer gleisbettung |
| EP1435991B1 (en) | 2001-10-19 | 2008-10-15 | Pharma Mar, S.A. | Use of aplidine for the treatment of pancreatic cancer |
| JP4584245B2 (ja) | 2003-03-12 | 2010-11-17 | ダナ−ファーバー キャンサー インスティテュート,インコーポレイテッド | 多発性骨髄腫治療用のアプリジン |
| KR20060002778A (ko) | 2003-03-12 | 2006-01-09 | 파르마 마르, 에스.에이. | 개선된 항종양 치료 |
-
2004
- 2004-03-12 KR KR1020057015665A patent/KR20060002778A/ko not_active Ceased
- 2004-03-12 US US10/546,750 patent/US7576188B2/en not_active Expired - Fee Related
- 2004-03-12 WO PCT/US2004/007606 patent/WO2004080421A2/en not_active Ceased
- 2004-03-12 AU AU2004220451A patent/AU2004220451B2/en not_active Ceased
- 2004-03-12 NZ NZ541634A patent/NZ541634A/en not_active IP Right Cessation
- 2004-03-12 CN CNA2009100039994A patent/CN101579520A/zh active Pending
- 2004-03-12 CN CNB2004800051794A patent/CN100409895C/zh not_active Expired - Fee Related
- 2004-03-12 CA CA002516572A patent/CA2516572A1/en not_active Abandoned
- 2004-03-12 UA UAA200508279A patent/UA83022C2/uk unknown
- 2004-03-12 CN CN2004800067241A patent/CN1761480B/zh not_active Expired - Lifetime
- 2004-03-12 EP EP04720399A patent/EP1620117A4/en not_active Withdrawn
- 2004-03-12 RU RU2005126819/15A patent/RU2341283C2/ru not_active IP Right Cessation
- 2004-03-12 JP JP2006507125A patent/JP2006519848A/ja active Pending
- 2004-03-12 MX MXPA05009741A patent/MXPA05009741A/es unknown
- 2004-12-03 UA UAA200509530A patent/UA82089C2/uk unknown
-
2005
- 2005-08-24 NO NO20053947A patent/NO20053947L/no not_active Application Discontinuation
-
2009
- 2009-04-30 US US12/433,028 patent/US20090227490A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| WO2004080421A2 (en) | 2004-09-23 |
| AU2004220451A1 (en) | 2004-09-23 |
| US20060178298A1 (en) | 2006-08-10 |
| RU2005126819A (ru) | 2006-01-20 |
| MXPA05009741A (es) | 2005-11-16 |
| WO2004080421A3 (en) | 2005-06-09 |
| UA82089C2 (uk) | 2008-03-11 |
| NO20053947D0 (no) | 2005-08-24 |
| AU2004220451B2 (en) | 2010-01-21 |
| CN1761480B (zh) | 2012-09-26 |
| JP2006519848A (ja) | 2006-08-31 |
| US7576188B2 (en) | 2009-08-18 |
| CN1753684A (zh) | 2006-03-29 |
| CN1761480A (zh) | 2006-04-19 |
| NZ541634A (en) | 2008-08-29 |
| EP1620117A4 (en) | 2009-07-29 |
| UA83022C2 (uk) | 2008-06-10 |
| CA2516572A1 (en) | 2004-09-23 |
| EP1620117A2 (en) | 2006-02-01 |
| CN101579520A (zh) | 2009-11-18 |
| KR20060002778A (ko) | 2006-01-09 |
| CN100409895C (zh) | 2008-08-13 |
| US20090227490A1 (en) | 2009-09-10 |
| RU2341283C2 (ru) | 2008-12-20 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC2A | Withdrawal, rejection or dismissal of laid open patent application |