NO20054111L - Fremgangsmate for fremtilling av tibolon - Google Patents

Fremgangsmate for fremtilling av tibolon

Info

Publication number: NO20054111L
Authority: NO; Norway
Prior art keywords: tibolone; procedure; producing; compound; formula
Prior art date: 2003-03-04

Application number

NO20054111A

Other languages

English (en)

Norwegian (no)

Other versions

NO20054111D0 (no

Inventor

Alan Kenneth Greenwood

Derek Mchattie

Parveen Bhatarah

Original Assignee

Resolution Chemicals Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2003-03-04

Filing date

2005-09-05

Publication date

2005-12-02

2005-09-05 Application filed by Resolution Chemicals Ltd filed Critical Resolution Chemicals Ltd

2005-09-05 Publication of NO20054111D0 publication Critical patent/NO20054111D0/no

2005-12-02 Publication of NO20054111L publication Critical patent/NO20054111L/no

Links

238000000034 method Methods 0.000 title abstract 3
WZDGZWOAQTVYBX-XOINTXKNSA-N tibolone Chemical compound C([C@@H]12)C[C@]3(C)[C@@](C#C)(O)CC[C@H]3[C@@H]1[C@H](C)CC1=C2CCC(=O)C1 WZDGZWOAQTVYBX-XOINTXKNSA-N 0.000 title 1
229960001023 tibolone Drugs 0.000 title 1
150000001875 compounds Chemical class 0.000 abstract 4
125000002877 alkyl aryl group Chemical group 0.000 abstract 1
125000003710 aryl alkyl group Chemical group 0.000 abstract 1
125000003118 aryl group Chemical group 0.000 abstract 1
229910052799 carbon Inorganic materials 0.000 abstract 1
125000004432 carbon atom Chemical group C* 0.000 abstract 1
125000000753 cycloalkyl group Chemical group 0.000 abstract 1
238000006317 isomerization reaction Methods 0.000 abstract 1
230000011987 methylation Effects 0.000 abstract 1
238000007069 methylation reaction Methods 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J51/00—Normal steroids with unmodified cyclopenta(a)hydrophenanthrene skeleton not provided for in groups C07J1/00 - C07J43/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Steroid Compounds (AREA)
Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

NO20054111A 2003-03-04 2005-09-05 Fremgangsmate for fremtilling av tibolon NO20054111L (no)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GBGB0304927.7A GB0304927D0 (en)	2003-03-04	2003-03-04	Process for the production of tibolone
PCT/GB2004/000887 WO2004078774A1 (fr)	2003-03-04	2004-03-03	Procede de production de tibolone

Publications (2)

Publication Number	Publication Date
NO20054111D0 NO20054111D0 (no)	2005-09-05
NO20054111L true NO20054111L (no)	2005-12-02

Family

ID=9954086

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO20054111A NO20054111L (no)	2003-03-04	2005-09-05	Fremgangsmate for fremtilling av tibolon

Country Status (12)

Country	Link
US (1)	US7884222B2 (fr)
EP (2)	EP1608670B1 (fr)
JP (1)	JP2006519248A (fr)
CN (1)	CN100420699C (fr)
AU (1)	AU2004218221C1 (fr)
BR (1)	BRPI0408104A (fr)
CA (1)	CA2517934A1 (fr)
GB (1)	GB0304927D0 (fr)
NO (1)	NO20054111L (fr)
NZ (1)	NZ542298A (fr)
WO (1)	WO2004078774A1 (fr)
ZA (1)	ZA200507281B (fr)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP2070942A1 (fr) *	2007-12-13	2009-06-17	Bayer Schering Pharma Aktiengesellschaft	Procédé d'aromatisation de 19-nor-androst-4-en-3-ons en estra-1,3,5(10)-triènes
JP5749261B2 (ja) *	2009-06-29	2015-07-15	メルツ・ファルマ・ゲーエムベーハー・ウント・コ・カーゲーアーアー	３，３，５，５−テトラメチルシクロヘキサノンを調製する方法
JP2014505721A (ja) *	2011-02-17	2014-03-06	ルピン・リミテッド	レボノルゲストレルを調製するための改良された方法
CN104292285A (zh) *	2014-09-30	2015-01-21	湖北三晶生物科技有限公司	一种高含量脱氢诺龙醋酸酯的合成工艺
CN107365340A (zh) *	2017-07-05	2017-11-21	湖北工业大学	一种3,5‑雌甾二烯‑3,17β‑二醋酸酯的制备方法
CN107200762A (zh) *	2017-07-12	2017-09-26	湖北共同生物科技有限公司	3,5‑雌甾二烯‑3,17β‑二醋酸酯的制备方法
CN109575094B (zh) *	2019-01-17	2021-01-26	浙江仙琚制药股份有限公司	替勃龙中间体的制备方法
CN110981930B (zh) *	2019-12-31	2021-04-20	浙江仙居君业药业有限公司	一种替勃龙的合成方法

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US3341557A (en) *	1961-06-05	1967-09-12	Upjohn Co	7-methyltestosterones
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CA2344686C (fr)	1998-10-16	2009-04-28	Akzo Nobel N.V.	Composition a degre eleve de purete renfermant (7.alpha.,17.alpha.)-17-hydroxy-7-methyl-19-nor-17-pregn-5(10)-en-20-yn-3-one
RU2417792C2 (ru)	1999-03-23	2011-05-10	Харбор Биосайенсиз, Инк.	Иммуномодуляторные стероиды
WO2000059920A2 (fr) *	1999-04-06	2000-10-12	Akzo Nobel N.V.	Androgenes actifs oralement
WO2000066613A1 (fr)	1999-04-30	2000-11-09	Research Corporation Technologies, Inc.	Agents de ciblage osseux contre l'ostéoporose
EP1189922A4 (fr)	1999-04-30	2002-08-14	Arch Dev Corp	Derives steroides
TW548277B (en) *	1999-07-16	2003-08-21	Akzo Nobel Nv	Orally active androgens
AUPQ342599A0 (en)	1999-10-14	1999-11-04	University Of Melbourne, The	Conjugates and uses thereof
EP1470151B1 (fr) *	2002-01-21	2009-12-30	N.V. Organon	Procede de preparation de 7-alpha-methylsteroides

2003
- 2003-03-04 GB GBGB0304927.7A patent/GB0304927D0/en not_active Ceased
2004
- 2004-03-03 CA CA002517934A patent/CA2517934A1/fr not_active Abandoned
- 2004-03-03 AU AU2004218221A patent/AU2004218221C1/en not_active Ceased
- 2004-03-03 JP JP2006505910A patent/JP2006519248A/ja active Pending
- 2004-03-03 ZA ZA200507281A patent/ZA200507281B/en unknown
- 2004-03-03 BR BRPI0408104-8A patent/BRPI0408104A/pt active Search and Examination
- 2004-03-03 CN CNB2004800112393A patent/CN100420699C/zh not_active Expired - Fee Related
- 2004-03-03 EP EP04716642.6A patent/EP1608670B1/fr not_active Expired - Lifetime
- 2004-03-03 EP EP10186130A patent/EP2497776A3/fr not_active Withdrawn
- 2004-03-03 NZ NZ542298A patent/NZ542298A/en not_active IP Right Cessation
- 2004-03-03 WO PCT/GB2004/000887 patent/WO2004078774A1/fr not_active Ceased
- 2004-03-03 US US10/548,114 patent/US7884222B2/en not_active Expired - Fee Related
2005
- 2005-09-05 NO NO20054111A patent/NO20054111L/no unknown

Also Published As

Publication number	Publication date
CA2517934A1 (fr)	2004-09-16
US20060173201A1 (en)	2006-08-03
CN100420699C (zh)	2008-09-24
EP2497776A2 (fr)	2012-09-12
BRPI0408104A (pt)	2006-03-01
JP2006519248A (ja)	2006-08-24
ZA200507281B (en)	2006-12-27
GB0304927D0 (en)	2003-04-09
EP1608670A1 (fr)	2005-12-28
EP2497776A3 (fr)	2013-01-02
WO2004078774A1 (fr)	2004-09-16
NZ542298A (en)	2008-07-31
AU2004218221C1 (en)	2011-07-07
AU2004218221A1 (en)	2004-09-16
CN1780849A (zh)	2006-05-31
EP1608670B1 (fr)	2013-09-11
US7884222B2 (en)	2011-02-08
NO20054111D0 (no)	2005-09-05
AU2004218221B2 (en)	2010-11-11

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NO20054111L (no)	2005-12-02	Fremgangsmate for fremtilling av tibolon
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