NO20054389L - Cyckloalkyl-substituerte alkansyrederivater, fremgangsmate for fremstilling og anvendelse derav som legemiddel - Google Patents

Cyckloalkyl-substituerte alkansyrederivater, fremgangsmate for fremstilling og anvendelse derav som legemiddel

Info

Publication number: NO20054389L
Authority: NO; Norway
Prior art keywords: preparation; acid derivatives; alkanoic acid; cycloalkyl; substituted alkanoic
Prior art date: 2003-02-27

Application number

NO20054389A

Other languages

English (en)

Norwegian (no)

Other versions

NO20054389D0 (no

Inventor

Heiner Glombik

Eugen Falk

Hans-Ludwig Schaefer

Stefanie Keil

Dirk Gretzke

Christian Stapper

Jochen Goerlitzer

Wolfgang Wendler

Original Assignee

Sanofi Aventis Deutschland

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2003-02-27

Filing date

2005-09-22

Publication date

2005-11-03

2005-09-22 Application filed by Sanofi Aventis Deutschland filed Critical Sanofi Aventis Deutschland

2005-09-22 Publication of NO20054389D0 publication Critical patent/NO20054389D0/no

2005-11-03 Publication of NO20054389L publication Critical patent/NO20054389L/no

Links

239000002253 acid Substances 0.000 title abstract 2
238000000034 method Methods 0.000 title abstract 2
239000003814 drug Substances 0.000 title 1
229940079593 drug Drugs 0.000 title 1
150000001875 compounds Chemical class 0.000 abstract 2
208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 2
208000035475 disorder Diseases 0.000 abstract 2
150000003839 salts Chemical class 0.000 abstract 2
WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 abstract 1
206010022489 Insulin Resistance Diseases 0.000 abstract 1
125000000753 cycloalkyl group Chemical group 0.000 abstract 1
235000014113 dietary fatty acids Nutrition 0.000 abstract 1
229930195729 fatty acid Natural products 0.000 abstract 1
239000000194 fatty acid Substances 0.000 abstract 1
150000004665 fatty acids Chemical class 0.000 abstract 1
239000008103 glucose Substances 0.000 abstract 1
208000030159 metabolic disease Diseases 0.000 abstract 1
230000002265 prevention Effects 0.000 abstract 1
208000001072 type 2 diabetes mellitus Diseases 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
- C07C275/28—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/17—Amides, e.g. hydroxamic acids having the group >N—C(O)—N< or >N—C(S)—N<, e.g. urea, thiourea, carmustine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
- A—HUMAN NECESSITIES
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- A61P11/06—Antiasthmatics
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- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
- C07C275/04—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to acyclic carbon atoms
- C07C275/06—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to acyclic carbon atoms of an acyclic and saturated carbon skeleton
- C07C275/10—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to acyclic carbon atoms of an acyclic and saturated carbon skeleton being further substituted by singly-bound oxygen atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
- C07C275/04—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to acyclic carbon atoms
- C07C275/20—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to acyclic carbon atoms of an unsaturated carbon skeleton
- C07C275/24—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing six-membered aromatic rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
- C07C275/26—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of rings other than six-membered aromatic rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/14—The ring being saturated

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Public Health (AREA)
Bioinformatics & Cheminformatics (AREA)
Veterinary Medicine (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Pharmacology & Pharmacy (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Diabetes (AREA)
Cardiology (AREA)
Hematology (AREA)
Heart & Thoracic Surgery (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
Obesity (AREA)
Dermatology (AREA)
Pulmonology (AREA)
Rheumatology (AREA)
Pain & Pain Management (AREA)
Hospice & Palliative Care (AREA)
Physical Education & Sports Medicine (AREA)
Endocrinology (AREA)
Urology & Nephrology (AREA)
Oncology (AREA)
Orthopedic Medicine & Surgery (AREA)
Virology (AREA)
Communicable Diseases (AREA)
Psychiatry (AREA)
Ophthalmology & Optometry (AREA)
Immunology (AREA)
Psychology (AREA)
Emergency Medicine (AREA)

NO20054389A 2003-02-27 2005-09-22 Cyckloalkyl-substituerte alkansyrederivater, fremgangsmate for fremstilling og anvendelse derav som legemiddel NO20054389L (no)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
DE10308356A DE10308356A1 (de)	2003-02-27	2003-02-27	Cycloalkyl substituierte Alkansäurederivate, Verfahren zu ihrer Herstellung und ihre Anwendung als Arzneimittel
PCT/EP2004/001587 WO2004076401A1 (de)	2003-02-27	2004-02-19	Cycloalkyl substituierte alkansaürederivate, verfahren zu ihrer herstellung und ihre anwendung als arzneimittel

Publications (2)

Publication Number	Publication Date
NO20054389D0 NO20054389D0 (no)	2005-09-22
NO20054389L true NO20054389L (no)	2005-11-03

Family

ID=32841933

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO20054389A NO20054389L (no)	2003-02-27	2005-09-22	Cyckloalkyl-substituerte alkansyrederivater, fremgangsmate for fremstilling og anvendelse derav som legemiddel

Country Status (22)

Country	Link
EP (1)	EP1599443B1 (pt)
JP (1)	JP2006519200A (pt)
KR (1)	KR20050115255A (pt)
CN (1)	CN100469761C (pt)
AR (1)	AR043431A1 (pt)
AT (1)	ATE538086T1 (pt)
BR (1)	BRPI0407871A (pt)
CA (1)	CA2516633A1 (pt)
CO (1)	CO5690544A2 (pt)
DE (1)	DE10308356A1 (pt)
HR (1)	HRP20050739A2 (pt)
IL (1)	IL170315A (pt)
MA (1)	MA27743A1 (pt)
MX (1)	MXPA05008990A (pt)
NO (1)	NO20054389L (pt)
PA (1)	PA8596701A1 (pt)
PE (1)	PE20040958A1 (pt)
PL (1)	PL377755A1 (pt)
RU (1)	RU2005129998A (pt)
TW (1)	TW200505830A (pt)
WO (1)	WO2004076401A1 (pt)
ZA (1)	ZA200505766B (pt)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US20040242568A1 (en)	2003-03-25	2004-12-02	Syrrx, Inc.	Dipeptidyl peptidase inhibitors
JP2007511467A (ja)	2003-05-14	2007-05-10	タケダサンディエゴインコーポレイテッド	ジペプチジルペプチダーゼインヒビター
MXPA06001601A (es)	2003-08-13	2006-08-25	Takeda Pharmaceutical	Derivados de 4-pirimidona y su uso como inhibidores de dipeptidilpeptidasa.
NZ566799A (en)	2005-09-14	2011-04-29	Takeda Pharmaceutical	Dipeptidyl peptidase inhibitors for treating diabetes
WO2007035629A2 (en)	2005-09-16	2007-03-29	Takeda Pharmaceutical Company Limited	Process for the preparation of pyrimidinedione derivatives
NZ566877A (en)	2005-09-29	2010-05-28	Sanofi Aventis	Phenyl-1,2,4-oxadiazolone derivatives, processes for their preparation and their use as pharmaceuticals
WO2007112347A1 (en)	2006-03-28	2007-10-04	Takeda Pharmaceutical Company Limited	Dipeptidyl peptidase inhibitors
TW200838536A (en)	2006-11-29	2008-10-01	Takeda Pharmaceutical	Polymorphs of succinate salt of 2-[6-(3-amino-piperidin-1-yl)-3-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-ylmethy]-4-fluor-benzonitrile and methods of use therefor
KR20250030215A (ko)	2023-08-24	2025-03-05	도레이첨단소재 주식회사	방류수 재활용 시스템

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IE61716B1 (en) *	1987-06-02	1994-11-30	Warner Lambert Co	Antihyperlipidemic and antiatherosclerotic urea compounds
US5420164A (en) *	1991-04-04	1995-05-30	Yoshitomi Pharmaceutical Industries, Ltd.	Cycloalkylurea compounds
GB9606805D0 (en) *	1996-03-30	1996-06-05	Glaxo Wellcome Inc	Medicaments
US6057338A (en) *	1997-04-04	2000-05-02	Merck & Co., Inc.	Somatostatin agonists
ATE260243T1 (de) *	1997-08-22	2004-03-15	Hoffmann La Roche	N-aroylphenylalaninderivate
AU1285499A (en) *	1997-10-30	1999-05-24	Merck & Co., Inc.	Somatostatin agonists
JP2002201171A (ja) *	2000-10-27	2002-07-16	Toa Eiyo Ltd	ウレアカルボン酸誘導体
JP2002201127A (ja) *	2000-12-28	2002-07-16	Pola Chem Ind Inc	ウレア誘導体
EP1372632A1 (en) *	2001-02-15	2004-01-02	Pfizer Products Inc.	Proliferative activator receptor (ppar) compounds

2003
- 2003-02-27 DE DE10308356A patent/DE10308356A1/de not_active Withdrawn
2004
- 2004-02-19 RU RU2005129998/04A patent/RU2005129998A/ru not_active Application Discontinuation
- 2004-02-19 PL PL377755A patent/PL377755A1/pl not_active Application Discontinuation
- 2004-02-19 EP EP04712498A patent/EP1599443B1/de not_active Expired - Lifetime
- 2004-02-19 MX MXPA05008990A patent/MXPA05008990A/es active IP Right Grant
- 2004-02-19 AT AT04712498T patent/ATE538086T1/de active
- 2004-02-19 BR BRPI0407871-3A patent/BRPI0407871A/pt not_active IP Right Cessation
- 2004-02-19 KR KR1020057016052A patent/KR20050115255A/ko not_active Ceased
- 2004-02-19 HR HR20050739A patent/HRP20050739A2/xx not_active Application Discontinuation
- 2004-02-19 CA CA002516633A patent/CA2516633A1/en not_active Abandoned
- 2004-02-19 WO PCT/EP2004/001587 patent/WO2004076401A1/de not_active Ceased
- 2004-02-19 JP JP2006501893A patent/JP2006519200A/ja active Pending
- 2004-02-19 CN CNB2004800054735A patent/CN100469761C/zh not_active Expired - Fee Related
- 2004-02-25 TW TW093104702A patent/TW200505830A/zh unknown
- 2004-02-27 PE PE2004000204A patent/PE20040958A1/es not_active Application Discontinuation
- 2004-02-27 PA PA20048596701A patent/PA8596701A1/es unknown
- 2004-02-27 AR ARP040100634A patent/AR043431A1/es not_active Application Discontinuation
2005
- 2005-07-19 ZA ZA200505766A patent/ZA200505766B/en unknown
- 2005-08-16 IL IL170315A patent/IL170315A/en not_active IP Right Cessation
- 2005-08-26 MA MA28466A patent/MA27743A1/fr unknown
- 2005-08-26 CO CO05085507A patent/CO5690544A2/es not_active Application Discontinuation
- 2005-09-22 NO NO20054389A patent/NO20054389L/no unknown

Also Published As

Publication number	Publication date
BRPI0407871A (pt)	2006-03-01
ZA200505766B (en)	2006-05-31
DE10308356A1 (de)	2004-09-09
PL377755A1 (pl)	2006-02-20
EP1599443B1 (de)	2011-12-21
JP2006519200A (ja)	2006-08-24
CN100469761C (zh)	2009-03-18
WO2004076401A1 (de)	2004-09-10
EP1599443A1 (de)	2005-11-30
CO5690544A2 (es)	2006-10-31
CA2516633A1 (en)	2004-09-10
ATE538086T1 (de)	2012-01-15
PA8596701A1 (es)	2004-09-16
CN1753865A (zh)	2006-03-29
MXPA05008990A (es)	2005-10-18
AU2004215678A1 (en)	2004-09-10
MA27743A1 (fr)	2006-02-01
HRP20050739A2 (en)	2006-08-31
NO20054389D0 (no)	2005-09-22
KR20050115255A (ko)	2005-12-07
PE20040958A1 (es)	2005-02-01
TW200505830A (en)	2005-02-16
RU2005129998A (ru)	2006-03-20
AR043431A1 (es)	2005-07-27
IL170315A (en)	2010-11-30

Publication	Publication Date	Title
NO20081367L (no)	2008-06-13	Fenyl- og pyridyl-1,2,4-oksadiazolonderivater med fenylgruppe, fremgangsmater for fremstilling derav og deres anvendelse som farmasoytika
NO20092293L (no)	2009-09-08	Sulfonyl-fenyl-2H-[1,2,4]oksodiazol-5-onderivater, fremgangsmate for fremstilling derav og deres anvendelse som farmasoytiske midler
NO20085064L (no)	2009-02-06	4,5-difenyl-pyrimidinyl-oksy eller -merkaptosubstituerte karboksylsyrer, fremgangsmate for deres fremstilling og anvendelse derav som medikamenter
NO20085066L (no)	2009-02-06	4,5-difenyl-pyrimidinyl-aminosubstituerte karboksylsyrer, fremgangsmate for deres fremstilling og anvendelse derav som medikamenter
PE20050255A1 (es)	2005-06-02	Nuevas cianotiazolidas y procedimiento para su preparacion como medicamentos
NO20085068L (no)	2009-02-04	Fenylamino-benzoksazolsubstituerte karboksylsyrer, fremgangsmate for deres fremstilling og anvendelse derav som medikamenter
NO20081369L (no)	2008-05-28	Fenyl- og pyridinyl-1,2,4-oksadiazolonderivater, fremgangsmate for deres fremstilling og deres anvendelse som farmasoytika
WO2007061661A3 (en)	2008-12-11	Inhibitors of 11-beta-hydroxy steroid dehydrogenase type 1
WO2011028947A3 (en)	2011-08-04	Heterocyclic compounds for the inhibition of pask
NO20054382L (no)	2005-09-21	Diarylsykloalkylderivater, deres fremstilling og deres anvendelse som legemiddel
HK1202448A1 (en)	2015-10-02	Topical formulation for administering a compound
WO2006099941A8 (de)	2006-11-09	Aminocarbonyl substituierte 8-n-benzimidazole, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
CY1109370T1 (el)	2014-07-02	Παραγωγα οξαδιαζολονης ως ppar δελτα αγωνιστες
NO20054408L (no)	2005-11-23	3(2-fenyl-oksazol-4-yl-metoksy)-cykloheksylmetoksyeddiksyrederivater og lignende forbindelser som PPAR-modulatorer for behandling av type 2 diabetes og arterosklerose
MX2009006913A (es)	2009-08-12	Uso de derivados de acido de piranona sustituidos para el tratamiento del sindrome metabolico.
NO20081681L (no)	2008-04-29	N-[1,3,4]-tiadiazol-2-yl-benzensulfonamider, fremgangsmate for fremstilling derav og deres anvendelse som farmasoytika
NO20064951L (no)	2006-10-30	1,3,4-oksadiazol-2-oner som PPAR delta-modulatorer og deres anvendelse
WO2006021000A3 (en)	2006-06-15	Substituted thienopyrrole carboxylic acid amides, pyrrolothiazole carboxylic acid amides, and related analogs as inhibitors of casein kinase i epsilon
TW200621732A (en)	2006-07-01	Arylcycloalkyl-substituted alkanoic acid derivatives, processes for their preparation and their use as pharmaceuticals
MXPA05008990A (es)	2005-10-18	Derivados de acido alcanoico sustituido con cicloalquilo, metodos para su produccion y su uso como medicamentos.
NO20065073L (no)	2006-11-29	Nye beta-agonister, metoder for deres fremstilling og deres anvendelse som medikamenter.
NO20040811L (no)	2004-05-19	Diarylcykloalkylderivater, fremgangsmate for deres fremstilling og deres anvendelse som PPAR-aktivatorer.
NO20063859L (no)	2006-08-29	Cykloalkylsubstituerte 7-amino-4-kinolon-3-karboksylsyrederivater, fremgangsmate for fremstilling derav og anvendelse derav som medikamenter
WO2010040862A3 (en)	2010-08-05	New activators for treating and/or preventing diseases or medical conditions which benefit from an increased transport of hyaluronan across a lipid bilayer
NO20054380L (no)	2005-09-21	Arylsykloalkylderivater med forgrenede sidekjeder som PPAR-reseptormodulatorer, deres fremstilling og deres anvendelse som legemiddel