NO20054538L - Fremgangsmate for fremstilling av antikonvulsantderivater av topiramat - Google Patents

Fremgangsmate for fremstilling av antikonvulsantderivater av topiramat

Info

Publication number: NO20054538L
Authority: NO; Norway
Prior art keywords: topiramate; preparation; anticonvulsant derivatives; derivatives; anticonvulsant
Prior art date: 2003-03-04

Application number

NO20054538A

Other languages

English (en)

Norwegian (no)

Inventor

Scott Mason Duncan

Joachim Ernst Berkner

John Mills

Original Assignee

Ortho Mcneil Pharm Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2003-03-04

Filing date

2005-10-03

Publication date

2005-10-03

2005-10-03 Application filed by Ortho Mcneil Pharm Inc filed Critical Ortho Mcneil Pharm Inc

2005-10-03 Publication of NO20054538L publication Critical patent/NO20054538L/no

Links

KJADKKWYZYXHBB-XBWDGYHZSA-N Topiramic acid Chemical compound C1O[C@@]2(COS(N)(=O)=O)OC(C)(C)O[C@H]2[C@@H]2OC(C)(C)O[C@@H]21 KJADKKWYZYXHBB-XBWDGYHZSA-N 0.000 title 1
230000001773 anti-convulsant effect Effects 0.000 title 1
239000001961 anticonvulsive agent Substances 0.000 title 1
229960003965 antiepileptics Drugs 0.000 title 1
229960004394 topiramate Drugs 0.000 title 1
-1 fructopyranose sulfamate derivatives Chemical class 0.000 abstract 1
238000004519 manufacturing process Methods 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C307/00—Amides of sulfuric acids, i.e. compounds having singly-bound oxygen atoms of sulfate groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C307/02—Monoamides of sulfuric acids or esters thereof, e.g. sulfamic acids
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H9/00—Compounds containing a hetero ring sharing at least two hetero atoms with a saccharide radical
- C07H9/02—Compounds containing a hetero ring sharing at least two hetero atoms with a saccharide radical the hetero ring containing only oxygen as ring hetero atoms
- C07H9/04—Cyclic acetals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
- A61P25/10—Antiepileptics; Anticonvulsants for petit-mal
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
- A61P25/12—Antiepileptics; Anticonvulsants for grand-mal
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C307/00—Amides of sulfuric acids, i.e. compounds having singly-bound oxygen atoms of sulfate groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C307/04—Diamides of sulfuric acids

Landscapes

Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Life Sciences & Earth Sciences (AREA)
Neurosurgery (AREA)
Public Health (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Biomedical Technology (AREA)
Pharmacology & Pharmacy (AREA)
Bioinformatics & Cheminformatics (AREA)
Animal Behavior & Ethology (AREA)
Pain & Pain Management (AREA)
Neurology (AREA)
Veterinary Medicine (AREA)
Biochemistry (AREA)
Biotechnology (AREA)
Genetics & Genomics (AREA)
Molecular Biology (AREA)
Pyridine Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Saccharide Compounds (AREA)

NO20054538A 2003-03-04 2005-10-03 Fremgangsmate for fremstilling av antikonvulsantderivater av topiramat NO20054538L (no)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US45186303P	2003-03-04	2003-03-04
PCT/US2004/006263 WO2004078769A1 (en)	2003-03-04	2004-03-02	Process for the preparation of anticonvulsant derivatives of topiramate

Publications (1)

Publication Number	Publication Date
NO20054538L true NO20054538L (no)	2005-10-03

Family

ID=32962650

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO20054538A NO20054538L (no)	2003-03-04	2005-10-03	Fremgangsmate for fremstilling av antikonvulsantderivater av topiramat

Country Status (26)

Country	Link
US (1)	US7157589B2 (pt)
EP (1)	EP1599490B8 (pt)
JP (1)	JP4725976B2 (pt)
KR (1)	KR20050119111A (pt)
CN (1)	CN100376591C (pt)
AR (1)	AR043466A1 (pt)
AT (1)	ATE421521T1 (pt)
AU (1)	AU2004217974A1 (pt)
BR (1)	BRPI0407967A (pt)
CA (1)	CA2517964A1 (pt)
CL (1)	CL2004000438A1 (pt)
DE (1)	DE602004019191D1 (pt)
DK (1)	DK1599490T3 (pt)
ES (1)	ES2254047T3 (pt)
HR (1)	HRP20050756A2 (pt)
MX (1)	MXPA05009384A (pt)
MY (1)	MY139235A (pt)
NO (1)	NO20054538L (pt)
NZ (1)	NZ541811A (pt)
PT (1)	PT1599490E (pt)
RU (1)	RU2333216C2 (pt)
SI (1)	SI1599490T1 (pt)
TW (1)	TW200504089A (pt)
UA (1)	UA81657C2 (pt)
WO (1)	WO2004078769A1 (pt)
ZA (1)	ZA200507995B (pt)

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* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US20060088886A1 (en) *	2004-10-25	2006-04-27	Anlong Ouyang	Topiramate analogs
US7638291B2 (en) *	2004-10-25	2009-12-29	Seradyn, Inc.	Immunoassays for topiramate
WO2007099388A1 (en) *	2006-03-01	2007-09-07	Glade Organics Private Limited	An improved process for the manufacture of topiramate
WO2008010231A2 (en) *	2006-05-26	2008-01-24	Alembic Limited	A process for the purification of topiramate
US20090076128A1 (en) *	2007-09-15	2009-03-19	Protia Llc	Deuterium-enriched topiramate
US9303038B2 (en)	2011-09-06	2016-04-05	Cellix Bio Private Limited	Compositions and methods for the treatment of epilepsy and neurological diseases
WO2013167990A1 (en)	2012-05-07	2013-11-14	Mahesh Kandula	Compositions and methods for the treatment of depression
SG11201407300VA (en)	2012-05-07	2014-12-30	Cellix Bio Private Ltd	Compositions and methods for the treatment of neurological disorders
WO2013168021A1 (en)	2012-05-07	2013-11-14	Mahesh Kandula	Compositions and methods for treatment of neuromuscular disorders and neurodegenerative disorders
US9522884B2 (en)	2012-05-08	2016-12-20	Cellix Bio Private Limited	Compositions and methods for the treatment of metabolic disorders
US9309233B2 (en)	2012-05-08	2016-04-12	Cellix Bio Private Limited	Compositions and methods for the treatment of blood clotting disorders
US9266823B2 (en)	2012-05-08	2016-02-23	Cellix Bio Private Limited	Compositions and methods for the treatment of parkinson's disease
US9403826B2 (en)	2012-05-08	2016-08-02	Cellix Bio Private Limited	Compositions and methods for the treatment of inflammatory disorders
WO2013167993A1 (en)	2012-05-08	2013-11-14	Mahesh Kandula	Compositions and methods for the treatment of neurological degenerative disorders
WO2013168001A1 (en)	2012-05-10	2013-11-14	Mahesh Kandula	Compositions and methods for the treatment of moderate to severe pain
US9499526B2 (en)	2012-05-10	2016-11-22	Cellix Bio Private Limited	Compositions and methods for the treatment of neurologic diseases
US9346742B2 (en)	2012-05-10	2016-05-24	Cellix Bio Private Limited	Compositions and methods for the treatment of fibromyalgia pain
US9403857B2 (en)	2012-05-10	2016-08-02	Cellix Bio Private Limited	Compositions and methods for the treatment of metabolic syndrome
US9242939B2 (en)	2012-05-10	2016-01-26	Cellix Bio Private Limited	Compositions and methods for the treatment of respiratory disorders
US9339484B2 (en)	2012-05-10	2016-05-17	Cellix Bio Private Limited	Compositions and methods for the treatment of restless leg syndrome and fibromyalgia
US9233161B2 (en)	2012-05-10	2016-01-12	Cellix Bio Private Limited	Compositions and methods for the treatment of neurological conditions
US9273061B2 (en)	2012-05-10	2016-03-01	Cellix Bio Private Limited	Compositions and methods for the treatment of chronic pain
WO2013168014A1 (en)	2012-05-10	2013-11-14	Mahesh Kandula	Compositions and methods for the treatment of familial amyloid polyneuropathy
WO2013167999A2 (en)	2012-05-10	2013-11-14	Mahesh Kandula	Compositions and methods for the treatment of neurologic diseases
WO2013167997A2 (en)	2012-05-10	2013-11-14	Mahesh Kandula	Compositions and methods for the treatment of metabolic syndrome
US9573927B2 (en)	2012-05-10	2017-02-21	Cellix Bio Private Limited	Compositions and methods for the treatment of severe pain
WO2013168015A1 (en)	2012-05-10	2013-11-14	Mahesh Kandula	Compositions and methods for the treatment of asthma and allergy
US9434729B2 (en)	2012-05-23	2016-09-06	Cellix Bio Private Limited	Compositions and methods for the treatment of periodontitis and rheumatoid arthritis
WO2013175347A2 (en)	2012-05-23	2013-11-28	Mahesh Kandula	Compositions and methods for the treatment of respiratory disorders
JP2015518854A (ja)	2012-05-23	2015-07-06	セリックスビオプライヴェートリミテッド	多発性硬化症の治療のための組成物および方法
NZ701832A (en)	2012-05-23	2016-08-26	Cellix Bio Private Ltd	Compositions and methods for treatment of inflammatory bowel disease
SG11201407326XA (en)	2012-05-23	2014-12-30	Cellix Bio Private Ltd	Compositions and methods for treatment of mucositis
WO2013175376A2 (en)	2012-05-23	2013-11-28	Mahesh Kandula	Compositions and methods for the treatment of local pain
US9108942B1 (en)	2014-11-05	2015-08-18	Mahesh Kandula	Compositions and methods for the treatment of moderate to severe pain
US9187427B2 (en)	2012-08-03	2015-11-17	Cellix Bio Private Limited	N-substituted nicotinamide compounds and compositions for the treatment migraine and neurologic diseases
WO2014037833A2 (en)	2012-09-06	2014-03-13	Mahesh Kandula	Compositions and methods for the treatment inflammation and lipid disorders
AU2013311349A1 (en)	2012-09-08	2014-11-27	Cellixbio Private Limited	Compositions and methods for treatment of inflammation and lipid disorders
US8652527B1 (en)	2013-03-13	2014-02-18	Upsher-Smith Laboratories, Inc	Extended-release topiramate capsules
US9101545B2 (en)	2013-03-15	2015-08-11	Upsher-Smith Laboratories, Inc.	Extended-release topiramate capsules
US9333187B1 (en)	2013-05-15	2016-05-10	Cellix Bio Private Limited	Compositions and methods for the treatment of inflammatory bowel disease
AU2014276346A1 (en)	2013-06-04	2015-12-24	Cellixbio Private Limited	Compositions and methods for the treatment of diabetes and pre-diabetes
US9096537B1 (en)	2014-12-31	2015-08-04	Mahesh Kandula	Compositions and methods for the treatment of mucositis
SG11201706952VA (en)	2014-09-26	2017-10-30	Cellix Bio Private Ltd	Compositions and methods for the treatment of epilepsy and neurological disorders
EP3201168B1 (en)	2014-09-29	2020-03-18	Cellix Bio Private Limited	Compounds and compositions for the treatment of multiple sclerosis
AU2014414316B2 (en)	2014-10-27	2020-04-09	Cellix Bio Private Limited	Three component salts of fumaric acid monomethyl ester with piperazine or ethylene diamine for the treatment of multiple sclerosis
US9284287B1 (en)	2014-11-05	2016-03-15	Cellix Bio Private Limited	Compositions and methods for the suppression of carbonic anhydrase activity
US9173877B1 (en)	2014-11-05	2015-11-03	Cellix Bio Private Limited	Compositions and methods for the treatment of local pain
US9290486B1 (en)	2014-11-05	2016-03-22	Cellix Bio Private Limited	Compositions and methods for the treatment of epilepsy
US9321716B1 (en)	2014-11-05	2016-04-26	Cellix Bio Private Limited	Compositions and methods for the treatment of metabolic syndrome
US9150557B1 (en)	2014-11-05	2015-10-06	Cellix Bio Private Limited	Compositions and methods for the treatment of hyperglycemia
US10208014B2 (en)	2014-11-05	2019-02-19	Cellix Bio Private Limited	Compositions and methods for the treatment of neurological disorders
US9175008B1 (en)	2014-11-05	2015-11-03	Cellix Bio Private Limited	Prodrugs of anti-platelet agents
WO2016088132A1 (en)	2014-12-01	2016-06-09	Cellix Bio Private Limited	Compositions and methods for the treatment of multiple sclerosis
US9206111B1 (en)	2014-12-17	2015-12-08	Cellix Bio Private Limited	Compositions and methods for the treatment of neurological diseases
JP6679616B2 (ja)	2015-01-06	2020-04-22	セリックスバイオプライヴェートリミテッドＣｅｌｌｉｘＢｉｏＰｒｉｖａｔｅＬｉｍｉｔｅｄ	炎症及び疼痛の治療のための組成物及び方法
CN106632530A (zh) *	2016-12-08	2017-05-10	陕西大生制药科技有限公司	高纯度托吡酯的制备方法
CN108341844A (zh) *	2018-04-25	2018-07-31	广州小桔生物科技有限公司	一种高纯度托吡酯的制备方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4513006A (en) *	1983-09-26	1985-04-23	Mcneil Lab., Inc.	Anticonvulsant sulfamate derivatives
US4582916A (en)	1983-09-26	1986-04-15	Mcneilab, Inc.	Chlorosulfate and azidosulfate esters of tetrahydro-2H-pyran-2-yl-methanol
IL103172A (en) *	1991-09-19	1997-01-10	Mcneilab Inc	Preparation of chlorosulfate and sulfamate derivatives of 2, 3:4, 5-bis-o-(1-methylethylidene)-beta-d-fructopyranose and (1-methylcyclohexyl) methanol
FR2704226B1 (fr) *	1993-04-22	1995-07-21	Sanofi Elf	3-desoxy oligosaccharides, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent.
FR2751334B1 (fr) *	1996-07-19	1998-10-16	Sanofi Sa	Polysaccharides synthetiques, procede pour leur preparation et compositions pharmaceutiques les contenant

2004
- 2004-02-03 UA UAA200508358A patent/UA81657C2/ru unknown
- 2004-03-01 US US10/790,274 patent/US7157589B2/en not_active Expired - Lifetime
- 2004-03-02 DK DK04716438T patent/DK1599490T3/da active
- 2004-03-02 AU AU2004217974A patent/AU2004217974A1/en not_active Abandoned
- 2004-03-02 CN CNB2004800057108A patent/CN100376591C/zh not_active Expired - Fee Related
- 2004-03-02 BR BRPI0407967-1A patent/BRPI0407967A/pt not_active IP Right Cessation
- 2004-03-02 SI SI200431098T patent/SI1599490T1/sl unknown
- 2004-03-02 EP EP04716438A patent/EP1599490B8/en not_active Expired - Lifetime
- 2004-03-02 ES ES04716438T patent/ES2254047T3/es not_active Expired - Lifetime
- 2004-03-02 PT PT04716438T patent/PT1599490E/pt unknown
- 2004-03-02 KR KR1020057016420A patent/KR20050119111A/ko not_active Ceased
- 2004-03-02 RU RU2005127626/04A patent/RU2333216C2/ru active
- 2004-03-02 WO PCT/US2004/006263 patent/WO2004078769A1/en not_active Ceased
- 2004-03-02 NZ NZ541811A patent/NZ541811A/en unknown
- 2004-03-02 AT AT04716438T patent/ATE421521T1/de not_active IP Right Cessation
- 2004-03-02 JP JP2006508970A patent/JP4725976B2/ja not_active Expired - Fee Related
- 2004-03-02 DE DE602004019191T patent/DE602004019191D1/de not_active Expired - Lifetime
- 2004-03-02 MX MXPA05009384A patent/MXPA05009384A/es active IP Right Grant
- 2004-03-02 CA CA002517964A patent/CA2517964A1/en not_active Abandoned
- 2004-03-02 HR HR20050756A patent/HRP20050756A2/xx not_active Application Discontinuation
- 2004-03-03 MY MYPI20040728A patent/MY139235A/en unknown
- 2004-03-03 TW TW093105458A patent/TW200504089A/zh unknown
- 2004-03-04 CL CL200400438A patent/CL2004000438A1/es unknown
- 2004-03-04 AR ARP040100680A patent/AR043466A1/es not_active Application Discontinuation
2005
- 2005-10-03 NO NO20054538A patent/NO20054538L/no not_active Application Discontinuation
- 2005-10-03 ZA ZA200507995A patent/ZA200507995B/en unknown

Also Published As

Publication number	Publication date
HK1088336A1 (zh)	2006-11-03
EP1599490A1 (en)	2005-11-30
AU2004217974A1 (en)	2004-09-16
AR043466A1 (es)	2005-07-27
EP1599490B1 (en)	2009-01-21
WO2004078769A1 (en)	2004-09-16
NZ541811A (en)	2008-07-31
DK1599490T3 (da)	2009-04-27
ES2254047T3 (es)	2009-05-14
CN1756760A (zh)	2006-04-05
SI1599490T1 (sl)	2009-06-30
US7157589B2 (en)	2007-01-02
HRP20050756A2 (en)	2006-07-31
JP2006519860A (ja)	2006-08-31
MY139235A (en)	2009-09-30
UA81657C2 (ru)	2008-01-25
DE602004019191D1 (de)	2009-03-12
CN100376591C (zh)	2008-03-26
US20040215004A1 (en)	2004-10-28
RU2005127626A (ru)	2006-01-27
BRPI0407967A (pt)	2006-03-07
ES2254047T1 (es)	2006-06-16
KR20050119111A (ko)	2005-12-20
EP1599490B8 (en)	2009-04-08
JP4725976B2 (ja)	2011-07-13
ZA200507995B (en)	2007-01-31
CL2004000438A1 (es)	2005-01-21
MXPA05009384A (es)	2006-02-28
ATE421521T1 (de)	2009-02-15
TW200504089A (en)	2005-02-01
CA2517964A1 (en)	2004-09-16
PT1599490E (pt)	2009-04-03
RU2333216C2 (ru)	2008-09-10

Legal Events

Date	Code	Title	Description
2010-11-01	FC2A	Withdrawal, rejection or dismissal of laid open patent application

Publication	Publication Date	Title
MXPA05009384A (es)	2006-02-28	Procedimiento para la preparacion de derivados de topiramato anticonvulsivos.
NO20054905L (no)	2006-01-25	2-acylamino-4-fenyltiazolderivater, fremgangsmate for deres fremstilling og anvendelse av de samme som i terapeutika
NO20053890L (no)	2005-10-20	Syntese av 4-amino-2-butenolklorider og anvendelse derav for fremstilling av 3-cyanokinoliner
WO2003097656A3 (en)	2004-06-10	Novel substituted sulfamate anticonvulsant derivatives
NO20074093L (no)	2008-02-07	Fremgangsmater for fremstilling av glukopyranosyl-substituerte benzyl-benzenderivater og mellomprodukter derav
MY133392A (en)	2007-11-30	Novel substituted pyrazole derivatives
MXPA04002067A (es)	2004-06-07	Nuevas dihidropteridinonas, procedimientos para su preparacion y su uso como medicamento.
YU91002A (sh)	2006-05-25	Derivati acilfenil-karbamida, postupak za njihovu proizvodnju i njihova primena kao leka
NO20071642L (no)	2007-06-01	N-Benzensulfonylsubstituerte anilino-pyrimidinanaloger
NO20062988L (no)	2006-08-28	Sykliske aminderivater med heteroarylring
BR0017030A (pt)	2003-01-07	Derivados de tiazolilamida
NO20044882L (no)	2004-11-09	Acyl-4-karboksylfenylurinstoffderivater, deres fremstilling og anvendelse
NO20054329L (no)	2005-11-21	Adamantanderivater, fremgangsmater for deres fremstilling og farmasoytiske sammensetninger som innbefatter slike
NO20062020L (no)	2006-07-10	1-amino-2-oksysubstituerte tetrahydronaftalenderivater, fremgangsmate for fremstilling derav, og deres anvendelse som antiflogistika
NO20080394L (no)	2008-03-14	N-(arylalkyl)-1H-pyrrolopyridin-2-karboksamidderivater, fremstilling og anvendelse derav
NO20070570L (no)	2007-04-10	Forbindelser.
NO20050088L (no)	2005-01-06	Kationisk substituerte difenylazefidinoner, fremgangsmate for deres fremstilling, medikamenter inneholdende nevnte forbindelser og anvendelse derav
PL379543A1 (pl)	2006-10-02	Wytwarzanie pochodnych 1,3-difenyloprop-2-en-1-onu
DK1261593T3 (da)	2003-12-01	8,8a-Dihydro-indeno[1,2-d]thiazol-derivater med en sulfonamido- eller sulfonosubstituent i 2-stillingen, en fremgangsmåde til fremstilling deraf og anvendelse deraf som lægemiddel
EA200600485A1 (ru)	2007-02-27	Способ получения производных 2-оксо-1-пирролидина
NO20062021L (no)	2006-07-07	Omleirede pentanoler, fremgangsmpte for fremstilling av dette, og deres anvendelse som antiflogistika
ATE202483T1 (de)	2001-07-15	Immuntolerante prothrombinkomplex-präparation
NO20070089L (no)	2007-01-05	DPP-IV inhibitorer
BR0011902A (pt)	2002-03-19	Compostos derivados de ciclopentano substituìdo, respectivos processos de preparação e formas cristalinas
YU63696A (sh)	1999-07-28	Novi fenilamidin-derivati, postupci za njihovo pripremanje i njihova primena kao lekova