NO20054861L - Antisens oligonukleotider (ODN) mot SMAD7 og anvendelser derav i det medisinske omradet - Google Patents

Antisens oligonukleotider (ODN) mot SMAD7 og anvendelser derav i det medisinske omradet

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Publication number
NO20054861L
NO20054861L NO20054861A NO20054861A NO20054861L NO 20054861 L NO20054861 L NO 20054861L NO 20054861 A NO20054861 A NO 20054861A NO 20054861 A NO20054861 A NO 20054861A NO 20054861 L NO20054861 L NO 20054861L
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Norway
Prior art keywords
odn
medical field
against smad7
smad7
oligonucleotides
Prior art date
Application number
NO20054861A
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English (en)
Other versions
NO334022B1 (no
Inventor
Giovanni Monteleone
Original Assignee
Giuliani Int Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Giuliani Int Ltd filed Critical Giuliani Int Ltd
Publication of NO20054861L publication Critical patent/NO20054861L/no
Publication of NO334022B1 publication Critical patent/NO334022B1/no

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    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • C12N15/1136—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against growth factors, growth regulators, cytokines, lymphokines or hormones
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
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    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
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Abstract

Oppfinnelsen angår antisens oligonukleotidsekvenser (ODN) mot Smad7 egnet modifisert,. og deres anvendelse i det medisinske området som terapeutisk biologiske midler, særlig ved behandling av kronisk inflammatorisk tarmsykdom så som Crohns sykdom og ulcererende kolitt.
NO20054861A 2003-04-02 2005-10-20 Antisens oligonukleotider (ODN) mot SMAD7 og anvendelser derav i det medisinske området NO334022B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT2003RM000149 ITRM20030149A1 (it) 2003-04-02 2003-04-02 Oligonucleotidi (odn) antisenso per smad7 e loro usi in campo medico
PCT/IT2004/000117 WO2004087920A1 (en) 2003-04-02 2004-03-08 Antisense oligonucleotides (odn) against smad7 and uses in medical field thereof

Publications (2)

Publication Number Publication Date
NO20054861L true NO20054861L (no) 2005-10-20
NO334022B1 NO334022B1 (no) 2013-11-18

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Family Applications (1)

Application Number Title Priority Date Filing Date
NO20054861A NO334022B1 (no) 2003-04-02 2005-10-20 Antisens oligonukleotider (ODN) mot SMAD7 og anvendelser derav i det medisinske området

Country Status (21)

Country Link
US (18) US7700757B2 (no)
EP (1) EP1608753B1 (no)
JP (2) JP4559411B2 (no)
KR (1) KR100822972B1 (no)
CN (1) CN100556461C (no)
AT (1) ATE417102T1 (no)
AU (1) AU2004225666B2 (no)
CA (1) CA2520541C (no)
CY (1) CY1108870T1 (no)
DE (1) DE602004018288D1 (no)
DK (1) DK1608753T3 (no)
ES (1) ES2316970T3 (no)
IT (1) ITRM20030149A1 (no)
MX (1) MXPA05010549A (no)
NO (1) NO334022B1 (no)
NZ (1) NZ542718A (no)
PL (1) PL1608753T3 (no)
PT (1) PT1608753E (no)
RU (1) RU2339697C2 (no)
SI (1) SI1608753T1 (no)
WO (1) WO2004087920A1 (no)

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