NO20054898L - Forbindelser med nootropisk virkning, deres fremstilling, farmasoytiske sammensetninger som inneholder disse samt deres anvendelse - Google Patents

Forbindelser med nootropisk virkning, deres fremstilling, farmasoytiske sammensetninger som inneholder disse samt deres anvendelse

Info

Publication number
NO20054898L
NO20054898L NO20054898A NO20054898A NO20054898L NO 20054898 L NO20054898 L NO 20054898L NO 20054898 A NO20054898 A NO 20054898A NO 20054898 A NO20054898 A NO 20054898A NO 20054898 L NO20054898 L NO 20054898L
Authority
NO
Norway
Prior art keywords
compounds
preparation
pharmaceutical compositions
compositions containing
action
Prior art date
Application number
NO20054898A
Other languages
English (en)
Inventor
Carlo Parini
Carlo Farina
Stefania Gagliardi
Marisa Martinelli
Carla Ghelardini
Original Assignee
Nikem Res Srl
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nikem Res Srl filed Critical Nikem Res Srl
Publication of NO20054898L publication Critical patent/NO20054898L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12—Antidiarrhoeals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Urology & Nephrology (AREA)
  • Hospice & Palliative Care (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicinal Preparation (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Den foreliggende oppfinnelsen tilveiebringer nye bisyklisk arylimidazoloner med noofropisk virkning (det vil si som beskytter og stimulerer hjemefimksjoner), smertestillende virkning og antihypersmertestillende virkning; fomten at det også tilveiebringes en fremgangsmåte for deres fremstiUing, fomten farmasøytiske sammensetninger som omfatter nevnte forbindelser, og hvor sammensetningene kan brukes for behandling av forskjelhge typer kognitiv svikt og for forskjellige typer av smerte.
NO20054898A 2003-03-24 2005-10-24 Forbindelser med nootropisk virkning, deres fremstilling, farmasoytiske sammensetninger som inneholder disse samt deres anvendelse NO20054898L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT000573A ITMI20030573A1 (it) 2003-03-24 2003-03-24 Composti ad azione nootropica, loro preparazione,
PCT/EP2004/050339 WO2004085438A2 (en) 2003-03-24 2004-03-22 Pyrroloimidazole derivatives, their preparation, pharmaceutical composition containing them, and their use as nootropic agents

Publications (1)

Publication Number Publication Date
NO20054898L true NO20054898L (no) 2005-10-24

Family

ID=33042696

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20054898A NO20054898L (no) 2003-03-24 2005-10-24 Forbindelser med nootropisk virkning, deres fremstilling, farmasoytiske sammensetninger som inneholder disse samt deres anvendelse

Country Status (23)

Country Link
US (3) US7544705B2 (no)
EP (1) EP1608655B8 (no)
JP (1) JP4920408B2 (no)
CN (1) CN100522963C (no)
AT (1) ATE401327T1 (no)
AU (1) AU2004224087B2 (no)
BR (1) BRPI0408601A (no)
CA (1) CA2520008C (no)
CY (1) CY1108401T1 (no)
DE (1) DE602004015089D1 (no)
DK (1) DK1608655T3 (no)
EA (1) EA009558B1 (no)
ES (1) ES2309534T3 (no)
HR (1) HRP20050833A2 (no)
IT (1) ITMI20030573A1 (no)
NO (1) NO20054898L (no)
NZ (1) NZ543154A (no)
PL (2) PL378939A1 (no)
PT (1) PT1608655E (no)
RS (1) RS20050725A (no)
SI (1) SI1608655T1 (no)
WO (1) WO2004085438A2 (no)
ZA (1) ZA200508578B (no)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ITMI20030573A1 (it) * 2003-03-24 2004-09-25 Nikem Research Srl Composti ad azione nootropica, loro preparazione,
EP1925304A1 (en) * 2006-11-15 2008-05-28 Nikem Research S.R.L. Pyrrolo[1,2-a]imidazoledione effective in the treatment of peripheral neurotoxicity induced by chemotherapeutic agents
AU2012201853B2 (en) * 2007-04-16 2013-06-27 Neurotune Ag Use of dimiracetam in the treatment of chronic pain
ITMI20070770A1 (it) * 2007-04-16 2008-10-17 Brane Discovery S R L Impiego di dimiracetam nel trattamento del dolore cronico
ES2865504T3 (es) 2008-10-16 2021-10-15 Univ Johns Hopkins Procedimientos y composiciones para la mejora de la función cognitiva
US9125898B2 (en) 2008-11-14 2015-09-08 Neurotune Ag Acetam derivatives for pain relief
AU2011215870B2 (en) * 2010-02-09 2016-01-28 The Johns Hopkins University Methods and compositions for improving cognitive function
PT2598504E (pt) * 2010-07-26 2014-07-14 Neurotune Ag Novo processo de fabrico de dimiracetam
US20140206667A1 (en) 2012-11-14 2014-07-24 Michela Gallagher Methods and compositions for treating schizophrenia
JP6433482B2 (ja) 2013-03-15 2018-12-05 エージンバイオ， インコーポレイテッド 認知機能を改善するための方法および組成物
WO2014144663A1 (en) 2013-03-15 2014-09-18 The Johns Hopkins University Methods and compositions for improving cognitive function
WO2016191288A1 (en) 2015-05-22 2016-12-01 Agenebio, Inc. Extended release pharmaceutical compositions of levetiracetam
JOP20190251A1 (ar) 2017-05-31 2019-10-21 Metys Pharmaceuticals AG تركيبات تآزرية تشتمل على (r)-ديميراسيتام (1) و(s)-ديميراسيتام (2) بنسبة غير راسيمية
CN113195494B (zh) 2018-12-04 2024-06-28 美蒂斯制药公司 包含非外消旋比例的R-2-（取代的磺酰基）-六氢-吡咯并[1,2-a]吡嗪-6（2H）-酮和S-2-（取代的磺酰基）-六氢-吡咯并[1,2- a]吡嗪-6（2H）-酮的协同组合物
BR112021010739A2 (pt) 2018-12-04 2021-08-24 Metys Pharmaceuticals AG Composições sinérgicas compreendendo (r)-(2-(2-oxopirrolidina-1-il)butanamida e (s)-2-(2-oxopirrolidina-1-il)butanamida) em uma proporção não racêmica

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4582838A (en) * 1984-08-24 1986-04-15 Warner-Lambert Company Derivatives of dihydro-1H-pyrrolo[1,2-c]imidazol-3,5-dione as cognition activators
IT1233860B (it) * 1988-02-08 1992-04-21 Isf Spa Derivati del peridroazacicloalca (1,2-a) imidazolo ad attivita' nootropa
US5200406A (en) * 1988-02-08 1993-04-06 I.S.F. Societa Per Azioni Pharmaceutically useful 2,5-dioxo-1H-octahydroimidazo[1,2-A]azepines
JP3400466B2 (ja) * 1991-10-28 2003-04-28 日本水産株式会社 高純度エイコサペンタエン酸またはそのエステルの製造方法
GB9123641D0 (en) * 1991-11-07 1992-01-02 Isf Spa Process
ITMI20030573A1 (it) * 2003-03-24 2004-09-25 Nikem Research Srl Composti ad azione nootropica, loro preparazione,
EP1925304A1 (en) * 2006-11-15 2008-05-28 Nikem Research S.R.L. Pyrrolo[1,2-a]imidazoledione effective in the treatment of peripheral neurotoxicity induced by chemotherapeutic agents

Also Published As

Publication number Publication date
EP1608655B8 (en) 2008-10-15
EP1608655B1 (en) 2008-07-16
EA200501501A1 (ru) 2006-04-28
US7544705B2 (en) 2009-06-09
DK1608655T3 (da) 2008-11-03
ITMI20030573A1 (it) 2004-09-25
PT1608655E (pt) 2008-10-07
ZA200508578B (en) 2007-04-25
EP1608655A2 (en) 2005-12-28
NZ543154A (en) 2008-03-28
US20100173945A1 (en) 2010-07-08
CA2520008C (en) 2011-08-23
CN100522963C (zh) 2009-08-05
SI1608655T1 (sl) 2008-12-31
BRPI0408601A (pt) 2006-03-07
CA2520008A1 (en) 2004-10-07
CY1108401T1 (el) 2014-02-12
EA009558B1 (ru) 2008-02-28
AU2004224087A1 (en) 2004-10-07
WO2004085438A3 (en) 2004-11-25
US7732473B2 (en) 2010-06-08
US20070027137A1 (en) 2007-02-01
AU2004224087B2 (en) 2010-04-01
ES2309534T3 (es) 2008-12-16
RS20050725A (sr) 2007-11-15
WO2004085438A2 (en) 2004-10-07
CN1756757A (zh) 2006-04-05
JP4920408B2 (ja) 2012-04-18
DE602004015089D1 (de) 2008-08-28
JP2006523198A (ja) 2006-10-12
HK1083837A1 (en) 2006-07-14
HRP20050833A2 (en) 2006-02-28
US20090163565A1 (en) 2009-06-25
PL1608655T3 (pl) 2009-03-31
ATE401327T1 (de) 2008-08-15
PL378939A1 (pl) 2006-06-12

Similar Documents

Publication Publication Date Title
NO20054898L (no) Forbindelser med nootropisk virkning, deres fremstilling, farmasoytiske sammensetninger som inneholder disse samt deres anvendelse
MXPA05005223A (es) Diaminotriazoles utiles como inhibidores de proteinas cinasas.
MY139730A (en) Cyclic protein tyrosine kinase inhibitors
TW200504015A (en) Indazole, benzisoxazole, and benzisothiazole kinase inhibitors
BRPI0412894A (pt) tienopiridina e furopiridina inibidores de quinases
ATE433973T1 (de) Azolylaminoazine als inhibitoren von proteinkinasen
CA2366932A1 (en) Cyclic protein tyrosine kinase inhibitors
AU3113902A (en) Thiazolyl inhibitors of tec family tyrosine kinases
TW200514776A (en) Aminotriazole compounds useful as inhibitors of protein kinases
NO20071915L (no) Diaminotriazolforbindelser nyttige som proteinkinaseinhibitorer
MXPA05010496A (es) Moduladores alostericos positivos del receptor de acetilcolina nicotinico.
DE60332433D1 (de) Azolylaminoazine als proteinkinasehemmer
DE60314603D1 (de) Zusammensetzungen brauchbar als protein-kinase- inhibitoren
EA200602241A1 (ru) Замещённые индазолы, композиции, содержащие указанные индазолы, способ их получения и применение
ATE468336T1 (de) Azolylaminoazine als proteinkinasehemmer
ATE464303T1 (de) Als inhibitoren von rock und anderen proteinkinasen geeignete zusammensetzungen
MXPA06011327A (es) Azaindoles utiles como inhibidores de jak y otras proteinas cinasas.
TR200500221T2 (tr) Farmasötik Maddeler Olarak Bisiklik Amino Asitler
NO20076447L (no) Bicykliske derivater som modulatorer av ionekanaler
MXPA05007792A (es) Prodrogas de propofol derivadas de aminoacido, composiciones y usos de las mismas.
ATE389651T1 (de) Als inhibitoren von c-met geeignete pyrrolzusammensetzungen
ATE414526T1 (de) Zubereitungen zur behandlung von arthritischen erscheinungen
BR112021022380A2 (pt) Inibidores de jak
ATE457027T1 (de) Substituierte 1,4,8-triazaspiroä4.5 decan-2-on- verbindungen zur behandlung von fettsucht
UA87494C2 (en) Azaindoles useful as inhibitors of jak and other protein kinases

Legal Events

Date Code Title Description
FC2A Withdrawal, rejection or dismissal of laid open patent application