NO20060678L - Triazolopyrimidinderivater som glykogensyntase-kinase 3-inhibitorer - Google Patents

Triazolopyrimidinderivater som glykogensyntase-kinase 3-inhibitorer

Info

Publication number: NO20060678L
Authority: NO; Norway
Prior art keywords: optionally substituted; alkyl; alkyloxy; polyhaloci; polyhaloc
Prior art date: 2003-07-16

Application number

NO20060678A

Other languages

English (en)

Norwegian (no)

Inventor

Ludwig Paul Cooymans

Eddy Jean Edgard Freyne

Werner Constant Joha Embrechts

Christopher John Love

Marc Willems

Nele Vandermaesen

Peter Jacobus Johan Buijnsters

Original Assignee

Janssen Pharmaceutica Nv

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2003-07-16

Filing date

2006-02-10

Publication date

2006-02-10

2006-02-10 Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv

2006-02-10 Publication of NO20060678L publication Critical patent/NO20060678L/no

Links

239000003572 glycogen synthase kinase 3 inhibitor Substances 0.000 title 1
YWBFPKPWMSWWEA-UHFFFAOYSA-O triazolopyrimidine Chemical class BrC1=CC=CC(C=2N=C3N=CN[N+]3=C(NCC=3C=CN=CC=3)C=2)=C1 YWBFPKPWMSWWEA-UHFFFAOYSA-O 0.000 title 1
125000004093 cyano group Chemical group *C#N 0.000 abstract 6
125000000217 alkyl group Chemical group 0.000 abstract 4
125000003545 alkoxy group Chemical group 0.000 abstract 3
UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 2
125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 2
125000002485 formyl group Chemical group [H]C(*)=O 0.000 abstract 2
125000005843 halogen group Chemical group 0.000 abstract 2
229910052739 hydrogen Inorganic materials 0.000 abstract 2
239000001257 hydrogen Substances 0.000 abstract 2
125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 2
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 2
125000004916 (C1-C6) alkylcarbonyl group Chemical group 0.000 abstract 1
125000003601 C2-C6 alkynyl group Chemical group 0.000 abstract 1
150000001204 N-oxides Chemical class 0.000 abstract 1
125000004453 alkoxycarbonyl group Chemical group 0.000 abstract 1
125000005196 alkyl carbonyloxy group Chemical group 0.000 abstract 1
125000000304 alkynyl group Chemical group 0.000 abstract 1
150000001412 amines Chemical group 0.000 abstract 1
125000003118 aryl group Chemical group 0.000 abstract 1
125000004541 benzoxazolyl group Chemical group O1C(=NC2=C1C=CC=C2)* 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
125000005842 heteroatom Chemical group 0.000 abstract 1
238000004519 manufacturing process Methods 0.000 abstract 1
238000000034 method Methods 0.000 abstract 1
125000002911 monocyclic heterocycle group Chemical group 0.000 abstract 1
229910052757 nitrogen Inorganic materials 0.000 abstract 1
229910052760 oxygen Inorganic materials 0.000 abstract 1
239000008194 pharmaceutical composition Substances 0.000 abstract 1
125000003373 pyrazinyl group Chemical group 0.000 abstract 1
125000002098 pyridazinyl group Chemical group 0.000 abstract 1
125000004076 pyridyl group Chemical group 0.000 abstract 1
125000000714 pyrimidinyl group Chemical group 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
125000001424 substituent group Chemical group 0.000 abstract 1
229910052717 sulfur Inorganic materials 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/16—Masculine contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/14—Drugs for dermatological disorders for baldness or alopecia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/04—Drugs for disorders of the muscular or neuromuscular system for myasthenia gravis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Veterinary Medicine (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Public Health (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
Neurosurgery (AREA)
Pain & Pain Management (AREA)
Psychiatry (AREA)
Diabetes (AREA)
Orthopedic Medicine & Surgery (AREA)
Physical Education & Sports Medicine (AREA)
Hematology (AREA)
Endocrinology (AREA)
Dermatology (AREA)
Hospice & Palliative Care (AREA)
Rheumatology (AREA)
Psychology (AREA)
Emergency Medicine (AREA)
Reproductive Health (AREA)
Obesity (AREA)
Oncology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

NO20060678A 2003-07-16 2006-02-10 Triazolopyrimidinderivater som glykogensyntase-kinase 3-inhibitorer NO20060678L (no)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
EP0350310		2003-07-16
PCT/EP2004/051455 WO2005012307A1 (en)	2003-07-16	2004-07-12	Triazolopyrimidine derivatives as glycogen synthase kinase 3 inhibitors

Publications (1)

Publication Number	Publication Date
NO20060678L true NO20060678L (no)	2006-02-10

Family

ID=34112425

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO20060678A NO20060678L (no)	2003-07-16	2006-02-10	Triazolopyrimidinderivater som glykogensyntase-kinase 3-inhibitorer

Country Status (26)

Country	Link
US (2)	US7560458B2 (pl)
EP (1)	EP1658292B1 (pl)
JP (1)	JP2009514782A (pl)
KR (1)	KR20060120393A (pl)
CN (1)	CN100404536C (pl)
AP (1)	AP2006003486A0 (pl)
AR (1)	AR045698A1 (pl)
AT (1)	ATE370142T1 (pl)
AU (1)	AU2004260738B2 (pl)
BR (1)	BRPI0412596A (pl)
CA (1)	CA2531333A1 (pl)
DE (1)	DE602004008303T2 (pl)
DK (1)	DK1658292T3 (pl)
EA (1)	EA010109B1 (pl)
ES (1)	ES2290754T3 (pl)
IL (1)	IL173139A (pl)
JO (1)	JO2460B1 (pl)
MX (1)	MXPA06000540A (pl)
NO (1)	NO20060678L (pl)
NZ (1)	NZ545058A (pl)
PA (1)	PA8607001A1 (pl)
PL (1)	PL1658292T3 (pl)
PT (1)	PT1658292E (pl)
TW (1)	TW200524935A (pl)
WO (1)	WO2005012307A1 (pl)
ZA (1)	ZA200600385B (pl)

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AU2004260738B2 (en) *	2003-07-16	2009-07-16	Janssen Pharmaceutica N.V.	Triazolopyrimidine derivatives as glycogen synthase kinase 3 inhibitors
WO2005012294A1 (en)	2003-07-30	2005-02-10	Rigel Pharmaceuticals, Inc.	2,4-pyrimidinediamine compounds for use in the treatment or prevention of autoimmune diseases
PT1660458E (pt) *	2003-08-15	2012-04-27	Novartis Ag	2,4-pirimidinodiaminas úteis no tratamento de doenças neoplásicas, desordens inflamatórias e do sistema imunitário
MXPA06002997A (es) *	2003-09-18	2007-02-08	Conforma Therapeutics Corp	Novedosos compuestos heterociclicos como inhibidores- hsp90.
BRPI0515482A (pt)	2004-09-20	2008-07-22	Xenon Pharmaceuticals Inc	derivados heterocìclicos e seus usos como agentes terapêuticos
BRPI0515500A (pt)	2004-09-20	2008-07-29	Xenon Pharmaceuticals Inc	derivados piridazina para inibição de estearoil-coa-desaturase
MX2007003332A (es)	2004-09-20	2007-06-05	Xenon Pharmaceuticals Inc	Derivados heterociclicos y su uso como inhibidores de estearoil-coa-desaturasa.
MX2007003318A (es)	2004-09-20	2007-05-18	Xenon Pharmaceuticals Inc	Derivados heterociclicos y su uso como agentes terapeuticos.
AU2005286647A1 (en)	2004-09-20	2006-03-30	Xenon Pharmaceuticals Inc.	Heterocyclic derivatives and their use as stearoyl-CoA desaturase inhibitors
AU2005286728A1 (en)	2004-09-20	2006-03-30	Xenon Pharmaceuticals Inc.	Heterocyclic derivatives and their use as mediators of stearoyl-CoA desaturase
CN101084211A (zh)	2004-09-20	2007-12-05	泽农医药公司	杂环衍生物及其作为治疗剂的用途
EP1812439B2 (en)	2004-10-15	2017-12-06	Takeda Pharmaceutical Company Limited	Kinase inhibitors
JP5118972B2 (ja)	2004-10-29	2013-01-16	テイボテク・フアーマシユーチカルズ	Ｈｉｖ阻害性二環式ピリミジン誘導体
US7563781B2 (en)	2005-01-14	2009-07-21	Janssen Pharmaceutica Nv	Triazolopyrimidine derivatives
CA2618646A1 (en)	2005-06-03	2007-11-15	Xenon Pharmaceuticals Inc.	Aminothiazole derivatives as human stearoyl-coa desaturase inhibitors
US20070203161A1 (en)	2006-02-24	2007-08-30	Rigel Pharmaceuticals, Inc.	Compositions and methods for inhibition of the jak pathway
BRPI0610876B8 (pt)	2005-06-08	2021-05-25	Rigel Pharmaceuticals Inc	composto, formulação farmacêutica, e métodos de inibir uma atividade de uma jak cinase, e de inibir uma cascata de transdução de sinal em que jak3 cinase desempenha um papel
EP2275095A3 (en)	2005-08-26	2011-08-17	Braincells, Inc.	Neurogenesis by muscarinic receptor modulation
EP2258358A3 (en)	2005-08-26	2011-09-07	Braincells, Inc.	Neurogenesis with acetylcholinesterase inhibitor
US8119655B2 (en)	2005-10-07	2012-02-21	Takeda Pharmaceutical Company Limited	Kinase inhibitors
EP1940389A2 (en)	2005-10-21	2008-07-09	Braincells, Inc.	Modulation of neurogenesis by pde inhibition
AU2006308889A1 (en)	2005-10-31	2007-05-10	Braincells, Inc.	GABA receptor mediated modulation of neurogenesis
ES2622493T3 (es)	2006-02-24	2017-07-06	Rigel Pharmaceuticals, Inc.	Composiciones y métodos para la inhibición de la ruta de JAK
US20100216734A1 (en)	2006-03-08	2010-08-26	Braincells, Inc.	Modulation of neurogenesis by nootropic agents
EP2382975A3 (en)	2006-05-09	2012-02-29	Braincells, Inc.	Neurogenesis by modulating angiotensin
US20100184806A1 (en)	2006-09-19	2010-07-22	Braincells, Inc.	Modulation of neurogenesis by ppar agents
SG158147A1 (en)	2006-10-09	2010-01-29	Takeda Pharmaceutical	Kinase inhibitors
CL2008001933A1 (es)	2007-06-29	2009-09-25	Millennium Pharm Inc	Compuestos derivados de pirimidina, inhibidores de la raf quinasa; compuestos intermediarios; procedimiento de preparacion; composicion farmaceutica; y su uso para tratar trastornos proliferativos, cardiacos, neurodegenerativos, inflamatorios, oseos, inmunologicos enfermedad viral, entre otros.
US7968536B2 (en) *	2007-06-29	2011-06-28	Millennium Pharmaceuticals, Inc.	Heterocyclic compounds useful as RAF kinase inhibitors
WO2010099217A1 (en)	2009-02-25	2010-09-02	Braincells, Inc.	Modulation of neurogenesis using d-cycloserine combinations
US8927547B2 (en)	2010-05-21	2015-01-06	Noviga Research Ab	Pyrimidine derivatives
DK2688883T3 (en)	2011-03-24	2016-09-05	Noviga Res Ab	pyrimidine
ES2655264T3 (es) *	2012-01-28	2018-02-19	Merck Patent Gmbh	Derivados de triazolo[4,5-d]pirimidina
US20150051202A1 (en)	2012-03-07	2015-02-19	Merck Patent Gmbh	Triazolopyrazine derivatives
EP2964648B1 (en)	2013-03-05	2016-11-16	Merck Patent GmbH	9-(aryl or heteroaryl)-2-(pyrazolyl, pyrrolidinyl or cyclopentyl)aminopurine derivatives as anticancer agents
AU2014224975B2 (en) *	2013-03-05	2017-09-14	Merck Patent Gmbh	Triazolo(4,5-d)pyrimidine derivatives for the treatment of diseases such as cancer
WO2014180524A1 (en)	2013-05-06	2014-11-13	Merck Patent Gmbh	Macrocycles as kinase inhibitors
US10414768B2 (en) *	2014-12-05	2019-09-17	Centre National De La Recherche Scientifique (Cnrs)	Compounds for treating cystic fibrosis
WO2017035528A1 (en)	2015-08-27	2017-03-02	Nantneuro, Llc	Triazolopyridines and triazolopyrimidines that lower stress-induced p-tau
WO2017156527A1 (en) *	2016-03-11	2017-09-14	H. Lee Moffitt Cancer Center And Research Institute, Inc.	Aurora kinase and janus kinase inhibitors for prevention of graft versus host disease
EP3920885A1 (en)	2019-02-08	2021-12-15	Frequency Therapeutics, Inc.	Valproic acid compounds and wnt agonists for treating ear disorders
WO2025104079A1 (en) *	2023-11-17	2025-05-22	Helmholtz-Zentrum für Infektionsforschung GmbH	Salicylic acid and picolinic acid derivatives as inhibitors of energy coupling factor (ecf) transporters for the treatment of bacterial infections

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JPS5962594A (ja) *	1982-09-30	1984-04-10	Ss Pharmaceut Co Ltd	３，５―ジ置換―トリアゾロピリミジン誘導体
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AU2002222293A1 (en) *	2000-12-19	2002-07-01	Smithkline Beecham P.L.C.	Pyrazolo(3,4-c)pyridines as gsk-3 inhibitors
AU2004260738B2 (en) *	2003-07-16	2009-07-16	Janssen Pharmaceutica N.V.	Triazolopyrimidine derivatives as glycogen synthase kinase 3 inhibitors

2004
- 2004-07-12 AU AU2004260738A patent/AU2004260738B2/en not_active Ceased
- 2004-07-12 JP JP2006519926A patent/JP2009514782A/ja not_active Withdrawn
- 2004-07-12 ES ES04766189T patent/ES2290754T3/es not_active Expired - Lifetime
- 2004-07-12 KR KR1020057024541A patent/KR20060120393A/ko not_active Ceased
- 2004-07-12 NZ NZ545058A patent/NZ545058A/en not_active IP Right Cessation
- 2004-07-12 US US10/564,844 patent/US7560458B2/en not_active Expired - Fee Related
- 2004-07-12 MX MXPA06000540A patent/MXPA06000540A/es active IP Right Grant
- 2004-07-12 PL PL04766189T patent/PL1658292T3/pl unknown
- 2004-07-12 EA EA200600258A patent/EA010109B1/ru not_active IP Right Cessation
- 2004-07-12 JO JO200496A patent/JO2460B1/en active
- 2004-07-12 CA CA002531333A patent/CA2531333A1/en not_active Abandoned
- 2004-07-12 AP AP2006003486A patent/AP2006003486A0/xx unknown
- 2004-07-12 AT AT04766189T patent/ATE370142T1/de active
- 2004-07-12 CN CNB2004800201486A patent/CN100404536C/zh not_active Expired - Fee Related
- 2004-07-12 EP EP04766189A patent/EP1658292B1/en not_active Expired - Lifetime
- 2004-07-12 DE DE602004008303T patent/DE602004008303T2/de not_active Expired - Lifetime
- 2004-07-12 DK DK04766189T patent/DK1658292T3/da active
- 2004-07-12 PT PT04766189T patent/PT1658292E/pt unknown
- 2004-07-12 WO PCT/EP2004/051455 patent/WO2005012307A1/en not_active Ceased
- 2004-07-12 BR BRPI0412596-7A patent/BRPI0412596A/pt not_active IP Right Cessation
- 2004-07-15 PA PA20048607001A patent/PA8607001A1/es unknown
- 2004-07-15 AR ARP040102496A patent/AR045698A1/es not_active Application Discontinuation
- 2004-07-15 TW TW093121066A patent/TW200524935A/zh unknown
2006
- 2006-01-12 IL IL173139A patent/IL173139A/en not_active IP Right Cessation
- 2006-01-13 ZA ZA200600385A patent/ZA200600385B/en unknown
- 2006-02-10 NO NO20060678A patent/NO20060678L/no not_active Application Discontinuation
2008
- 2008-09-16 US US12/211,361 patent/US20090036471A1/en not_active Abandoned

Also Published As

Publication number	Publication date
CA2531333A1 (en)	2005-02-10
CN1823068A (zh)	2006-08-23
AP2006003486A0 (en)	2006-02-28
US7560458B2 (en)	2009-07-14
TW200524935A (en)	2005-08-01
IL173139A (en)	2010-04-29
DE602004008303T2 (de)	2008-05-08
DE602004008303D1 (de)	2007-09-27
EP1658292A1 (en)	2006-05-24
ES2290754T3 (es)	2008-02-16
NZ545058A (en)	2008-05-30
US20090036471A1 (en)	2009-02-05
JO2460B1 (en)	2009-01-20
EP1658292B1 (en)	2007-08-15
MXPA06000540A (es)	2006-03-30
KR20060120393A (ko)	2006-11-27
CN100404536C (zh)	2008-07-23
ZA200600385B (en)	2007-05-30
AU2004260738A1 (en)	2005-02-10
ATE370142T1 (de)	2007-09-15
JP2009514782A (ja)	2009-04-09
PA8607001A1 (es)	2005-05-10
AR045698A1 (es)	2005-11-09
BRPI0412596A (pt)	2006-09-19
AU2004260738B2 (en)	2009-07-16
PT1658292E (pt)	2007-10-25
WO2005012307A1 (en)	2005-02-10
IL173139A0 (en)	2006-06-11
PL1658292T3 (pl)	2008-01-31
US20060205721A1 (en)	2006-09-14
EA200600258A1 (ru)	2006-06-30
EA010109B1 (ru)	2008-06-30
DK1658292T3 (da)	2007-11-12

Legal Events

Date	Code	Title	Description
2011-02-28	FC2A	Withdrawal, rejection or dismissal of laid open patent application

Publication	Publication Date	Title
NO20060678L (no)	2006-02-10	Triazolopyrimidinderivater som glykogensyntase-kinase 3-inhibitorer
WO2005012304A3 (en)	2007-04-26	Triazolopyrimidine derivatives as glycogen synthase kinase 3 inhibitors
DK1442019T3 (da)	2008-01-14	Amidderivater som glycogensynthasekinase 3- beta-inhibitorer
PE20161066A1 (es)	2016-10-30	Derivados de piperidinil-indol como inhibidores del factor de complemento b y usos de los mismos
CO6241157A2 (es)	2011-01-20	"derivados de 6-(pirrolidin-3-il)-1h-pirazolo{3,4-d}pirimidin-4(5h)-ona utiles como inhibidores de pde9"
CY1112642T1 (el)	2016-02-10	Παραγωγα 4-(πυριδιν-4-υλο)-1η-[1,3,5]τριαζιν-2-ονης ως αναστολεις της gsκ3-βετα για τη θεραπεια των νευροεκφυλιστικων ασθενειων
NO20041911L (no)	2004-05-10	Heteroarylaminer som glykogensyntase-kinase 3beta-inhibitorer (GSK3-inhibitorer)
AR030553A1 (es)	2003-08-27	Uso de derivados de tiazolilo 2,4-disustituidos para la fabricacion de un medicamento para la prevencion o el tratamiento de enfermedades mediadas a traves de citoquinas, derivados de tiazolilo 2,4-disustituidos, composiciones farmaceuticas que los comprenden, procesos para preparar dichos derivados
PE20191613A1 (es)	2019-11-05	Compuestos de pirazolo[1,5-a]piridina sustituidos como inhibidores de la quinasa ret
AR067327A1 (es)	2009-10-07	Derivados de piperidina / piperazina
NO2012010I2 (no)	2013-09-02	Rilpivirin samt farmasøytisk akseptable addisjonssalter derav innbefattende hydrokloridsaltet av Rilpivirin
WO2008007123A3 (en)	2008-02-28	Pharmaceutical compounds
NO20073960L (no)	2007-09-24	Pyrazolderivater for inhibering av CDK og GSK
NO20073926L (no)	2007-10-01	Pyrazolforbindelser som modulerer aktivitet av CDK-, GSK- og aurorakinaser
MX2012001661A (es)	2012-03-16	Mezclas de pesticidas mesoionicos.
RU2009148320A (ru)	2011-07-20	Производные пиперидина/пиперазина
CY1114767T1 (el)	2016-12-14	Ν,ν-υποκατεστημενες ενωσεις 3-αμινοπυρρολιδινης χρησιμες ως αναστολεις επαναπροσληψης μονοαμινων
BR0211887A (pt)	2004-09-21	Derivados de triazolil 2-amino-4,5-trissubstituìdo
CO2020012353A2 (es)	2021-01-18	Compuestos de pirazol sustituidos con heteroarilo y uso farmacéutico de los mismos
AR066154A1 (es)	2009-07-29	Derivados de piperidina / piperazina
DE602007004740D1 (de)	2010-03-25	Antibiotische spiroderivate
EP1867331A4 (en)	2009-04-08	TRIAZOLE DERIVATIVE AND USE THEREOF
AR070073A1 (es)	2010-03-10	Derivados de imidazo[1, 2 - a]piridin-2-carboxamidas, intermediarios para su preparacion, una composicion farmaceutica que los comprende y su uso en la fabricacion de medicamentos para el tratamiento de enfermedades que implican a los receptores not.
PE20252682A1 (es)	2025-11-24	Derivados de oxazolo[4,5-b]pirazina y oxazolo[4,5-b]piridina como inhibidores de nlrp3 para el tratamiento de, por ejemplo, enfermedades inflamatorias
WO2005095399A3 (fr)	2006-06-01	Derives pyrrolo (2,3-b) pyridine, leur preparation et leur utilisation pharmaceutique comme inhibiteurs de kinases