NO20061402L - Anti-tumorformuleringer som omfatter defibrotid alene eller i kombinasjon med andre antitumormidler - Google Patents
Anti-tumorformuleringer som omfatter defibrotid alene eller i kombinasjon med andre antitumormidlerInfo
- Publication number
- NO20061402L NO20061402L NO20061402A NO20061402A NO20061402L NO 20061402 L NO20061402 L NO 20061402L NO 20061402 A NO20061402 A NO 20061402A NO 20061402 A NO20061402 A NO 20061402A NO 20061402 L NO20061402 L NO 20061402L
- Authority
- NO
- Norway
- Prior art keywords
- combination
- antitumor agents
- formulations
- defibrotide
- alone
- Prior art date
Links
- JNWFIPVDEINBAI-UHFFFAOYSA-N [5-hydroxy-4-[4-(1-methylindol-5-yl)-5-oxo-1H-1,2,4-triazol-3-yl]-2-propan-2-ylphenyl] dihydrogen phosphate Chemical compound C1=C(OP(O)(O)=O)C(C(C)C)=CC(C=2N(C(=O)NN=2)C=2C=C3C=CN(C)C3=CC=2)=C1O JNWFIPVDEINBAI-UHFFFAOYSA-N 0.000 title abstract 2
- 230000000259 anti-tumor effect Effects 0.000 title abstract 2
- 229960004120 defibrotide Drugs 0.000 title abstract 2
- 238000009472 formulation Methods 0.000 title abstract 2
- 239000000203 mixture Substances 0.000 title abstract 2
- 239000002246 antineoplastic agent Substances 0.000 title 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 239000013543 active substance Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/17—Amides, e.g. hydroxamic acids having the group >N—C(O)—N< or >N—C(S)—N<, e.g. urea, thiourea, carmustine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7088—Compounds having three or more nucleosides or nucleotides
- A61K31/711—Natural deoxyribonucleic acids, i.e. containing only 2'-deoxyriboses attached to adenine, guanine, cytosine or thymine and having 3'-5' phosphodiester links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/665—Phosphorus compounds having oxygen as a ring hetero atom, e.g. fosfomycin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7088—Compounds having three or more nucleosides or nucleotides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Molecular Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Biochemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT001714A ITMI20031714A1 (it) | 2003-09-05 | 2003-09-05 | Formazioni ad azione antitumorale. |
| US53934404P | 2004-01-28 | 2004-01-28 | |
| PCT/EP2004/009723 WO2005023273A1 (en) | 2003-09-05 | 2004-08-27 | Anti-tumor formulations comprising defibrotide alone or in combination with other anti-tumor agents |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NO20061402L true NO20061402L (no) | 2006-03-28 |
Family
ID=37064585
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20061402A NO20061402L (no) | 2003-09-05 | 2006-03-28 | Anti-tumorformuleringer som omfatter defibrotid alene eller i kombinasjon med andre antitumormidler |
Country Status (23)
| Country | Link |
|---|---|
| US (2) | US8551967B2 (de) |
| EP (1) | EP1660100B1 (de) |
| JP (1) | JP4671962B2 (de) |
| KR (1) | KR20060061367A (de) |
| CN (1) | CN100490820C (de) |
| AT (1) | ATE399558T1 (de) |
| AU (1) | AU2004269896B2 (de) |
| BR (1) | BRPI0414114A (de) |
| CA (1) | CA2537226C (de) |
| DE (1) | DE602004014787D1 (de) |
| DK (1) | DK1660100T3 (de) |
| ES (1) | ES2308223T3 (de) |
| IL (1) | IL173785A0 (de) |
| IS (1) | IS8334A (de) |
| IT (1) | ITMI20031714A1 (de) |
| MX (1) | MXPA06002489A (de) |
| NO (1) | NO20061402L (de) |
| PT (1) | PT1660100E (de) |
| RS (1) | RS20060154A (de) |
| RU (1) | RU2348413C2 (de) |
| UA (1) | UA83500C2 (de) |
| WO (1) | WO2005023273A1 (de) |
| ZA (1) | ZA200601852B (de) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2006222045B2 (en) * | 2005-03-03 | 2011-10-20 | Gentium Spa | Oligodeoxyribonucleotides of 4000-10000 Dalton for treating tumors |
| EP1872787A1 (de) * | 2006-06-27 | 2008-01-02 | Gentium S.p.A. | Verwendung von Defibrotide als Heparanasehemmer |
| EP2103689A1 (de) | 2008-03-19 | 2009-09-23 | Gentium S.p.A. | Synthetische Phosphodiester-Oligonukleotide und deren therapeutische Verwendungen |
| EP2637672B1 (de) | 2010-11-12 | 2018-08-22 | Gentium S.r.l. | Defibrotid zur prophylaxe und/oder behandlung von graft-versus-host-reaktion (gvhr) |
| ES2660969T5 (es) | 2012-06-22 | 2021-09-03 | Gentium S R L | Método basado en euglobulina para determinar la actividad biológica de defibrotida |
| EP3026122A1 (de) | 2014-11-27 | 2016-06-01 | Gentium S.p.A. | Zellenbasiertes Verfahren zur Bestimmung der Wirksamkeit von Defibrotid |
| US10380734B2 (en) * | 2017-02-27 | 2019-08-13 | Aniket Bharat Parikh | System, method and computer program product for security analysis of jewelry items |
| TW201909904A (zh) * | 2017-08-03 | 2019-03-16 | 愛爾蘭商爵士製藥愛爾蘭有限責任公司 | 高濃度調配物 |
| CN112236149A (zh) | 2018-04-12 | 2021-01-15 | 贾兹制药公司 | 用于预防和治疗细胞因子释放综合征和与免疫耗竭相关的神经毒性的去纤苷 |
| US20220023533A1 (en) | 2018-12-07 | 2022-01-27 | Jazz Phrmaceticals Ireland Limited | Subcutaneous delivery of high concentration formulations |
| EP4110287A1 (de) | 2020-02-28 | 2023-01-04 | Jazz Pharmaceuticals Ireland Limited | Abgabe von niedrigviskosen formulierungen |
| TW202308659A (zh) | 2021-05-06 | 2023-03-01 | 愛爾蘭商爵士製藥愛爾蘭有限責任公司 | 用於急性呼吸窘迫症候群之治療及預防的去纖維蛋白多核苷酸 |
Family Cites Families (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2154279A1 (de) | 1970-11-03 | 1972-05-25 | Crinos Industria Farmaco | Medikamente für das fibrinolytische System |
| IT1043823B (it) | 1970-11-03 | 1980-02-29 | Prephar | Procedimento per l estrazione di acidi nucleici da organi animali |
| US3899481A (en) | 1970-11-03 | 1975-08-12 | Crinos Industria Farmaco | Process for the controlled partial degradation of deoxyribonucleic acid extracted from animal organs |
| US4853221A (en) * | 1980-11-13 | 1989-08-01 | Warner-Lambert Company | Method for treating non-small cell lung cancer, head and neck cancers and breast cancer |
| IT1170214B (it) * | 1983-09-12 | 1987-06-03 | Crinos Industria Farmaco | Composizione farmaceutica per la cura delle arteriopatie periferiche |
| IT1206341B (it) * | 1984-02-16 | 1989-04-14 | Crinos Industria Farmaco | Composizione farmaceutica per il trattamento dell'ischemia acuta del miocardio. |
| US4694134A (en) | 1985-05-28 | 1987-09-15 | Ajax Magnethermic Corporation | Apparatus for overheating edges of skelp for the production of compression welded pipe |
| US5223609A (en) | 1986-04-17 | 1993-06-29 | Crinos Industria Farmacobiologica S.P.A. | Process for obtaining chemically defined and reproducible polydeoxyribonucleotides |
| IT1190313B (it) | 1986-04-17 | 1988-02-16 | Crinos Industria Farmaco | Procedimento per l'ottenimento di polidesossiribonucleotidi chimicamente definiti e riproducibili e prodotto farmacologicamente attivo risultante |
| US6699985B2 (en) * | 1991-08-21 | 2004-03-02 | Arsinur Burcoglu | Method of treating HIV infection and related secondary infections thereof |
| US5977083A (en) | 1991-08-21 | 1999-11-02 | Burcoglu; Arsinur | Method for using polynucleotides, oligonucleotides and derivatives thereof to treat various disease states |
| IT1252174B (it) | 1991-12-09 | 1995-06-05 | Crinos Industria Farmaco | Oligodesossimibonucleotidi ad attivita' antiischemica e procedimenti per il loro ottenimento |
| DE9202745U1 (de) | 1992-03-02 | 1992-04-30 | Howmedica Gmbh, 2314 Schoenkirchen | Vorrichtung zum Verspannen von Wirbeln der menschlichen Wirbelsäule |
| US5578716A (en) | 1993-12-01 | 1996-11-26 | Mcgill University | DNA methyltransferase antisense oligonucleotides |
| AU754242B2 (en) * | 1997-04-28 | 2002-11-07 | Arsinur Burcoglu | Method of treating HIV infection and related secondary infections thereof |
| WO1998054313A2 (en) | 1997-05-30 | 1998-12-03 | Mcgill University | Dna methyltransferase genomic sequences and antisense oligonucleotides |
| US6177545B1 (en) | 1997-09-02 | 2001-01-23 | Insight Strategy & Marketing Ltd. | Heparanase specific molecular probes and their use in research and medical applications |
| DE19740384A1 (de) | 1997-09-08 | 1999-03-11 | Max Delbrueck Centrum | Antisense Oligodesoxynukleotide (ODN) gegen Proteinkinase C (PKC)-Isoformen, ihre Verwendung und pharmazeutische Zubereitungen dieser ODN |
| WO2000074634A2 (en) * | 1999-06-03 | 2000-12-14 | Au Jessie L S | Methods and compositions for modulating cell proliferation and cell death |
| EP1406930A4 (de) * | 2000-12-29 | 2007-01-10 | Savient Pharmaceuticals Inc | "isolierte moleküle mit sulfatierte gruppierungen enthaltenden epitopen, antikörper gegen solche epitope und verwendungen davon" |
| US6770753B2 (en) | 2001-07-05 | 2004-08-03 | The Trustees Of Columbia University In The City Of New York | Phosphorothioate antisense heparanase oligonucleotides |
| WO2003027313A2 (en) | 2001-09-24 | 2003-04-03 | The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | SUPPRESSORS OF CpG OLIGONUCLEOTIDES AND METHODS OF USE |
| US20050032882A1 (en) * | 2002-03-06 | 2005-02-10 | Sophie Chen | Botanical extract compositions and methods of use |
| CA2487171A1 (en) * | 2002-05-31 | 2003-12-11 | Klinikum Der Universitat Regensburg | Method for the protection of endothelial and epithelial cells during chemotherapy |
| WO2004003166A2 (en) * | 2002-07-01 | 2004-01-08 | Savient Pharmaceuticals, Inc. | Antibodies and uses thereof |
| CA2501719C (en) | 2002-08-06 | 2013-02-05 | Toray Industries, Inc. | Remedy or preventive for kidney disease and method of diagnosing kidney disease |
| DE10244453A1 (de) | 2002-09-24 | 2004-04-01 | Phenomiques Gmbh | Hemmung der Proteinkinase C-alpha zur Behandlung von Krankheiten |
| US7803781B2 (en) | 2003-02-28 | 2010-09-28 | Isis Pharmaceuticals, Inc. | Modulation of growth hormone receptor expression and insulin-like growth factor expression |
| AU2006222045B2 (en) | 2005-03-03 | 2011-10-20 | Gentium Spa | Oligodeoxyribonucleotides of 4000-10000 Dalton for treating tumors |
| EP1872787A1 (de) | 2006-06-27 | 2008-01-02 | Gentium S.p.A. | Verwendung von Defibrotide als Heparanasehemmer |
| EP1982722A1 (de) | 2007-04-16 | 2008-10-22 | Gentium S.p.A. | Verwendung von Oligotid zur Behandlung von Nierenerkrankungen |
-
2003
- 2003-09-05 IT IT001714A patent/ITMI20031714A1/it unknown
-
2004
- 2004-08-27 DE DE602004014787T patent/DE602004014787D1/de not_active Expired - Lifetime
- 2004-08-27 MX MXPA06002489A patent/MXPA06002489A/es active IP Right Grant
- 2004-08-27 KR KR1020067004451A patent/KR20060061367A/ko not_active Withdrawn
- 2004-08-27 CN CNB2004800253315A patent/CN100490820C/zh not_active Expired - Fee Related
- 2004-08-27 RS YUP-2006/0154A patent/RS20060154A/sr unknown
- 2004-08-27 ES ES04764686T patent/ES2308223T3/es not_active Expired - Lifetime
- 2004-08-27 EP EP04764686A patent/EP1660100B1/de not_active Expired - Lifetime
- 2004-08-27 DK DK04764686T patent/DK1660100T3/da active
- 2004-08-27 ZA ZA200601852A patent/ZA200601852B/en unknown
- 2004-08-27 RU RU2006109210/15A patent/RU2348413C2/ru not_active IP Right Cessation
- 2004-08-27 PT PT04764686T patent/PT1660100E/pt unknown
- 2004-08-27 BR BRPI0414114-8A patent/BRPI0414114A/pt not_active IP Right Cessation
- 2004-08-27 UA UAA200602374A patent/UA83500C2/uk unknown
- 2004-08-27 JP JP2006525096A patent/JP4671962B2/ja not_active Expired - Fee Related
- 2004-08-27 AU AU2004269896A patent/AU2004269896B2/en not_active Ceased
- 2004-08-27 AT AT04764686T patent/ATE399558T1/de active
- 2004-08-27 WO PCT/EP2004/009723 patent/WO2005023273A1/en not_active Ceased
- 2004-08-27 CA CA2537226A patent/CA2537226C/en not_active Expired - Fee Related
-
2006
- 2006-02-16 IL IL173785A patent/IL173785A0/en unknown
- 2006-02-28 IS IS8334A patent/IS8334A/is unknown
- 2006-03-02 US US11/366,243 patent/US8551967B2/en not_active Expired - Fee Related
- 2006-03-28 NO NO20061402A patent/NO20061402L/no not_active Application Discontinuation
-
2013
- 2013-09-06 US US14/019,674 patent/US20140005256A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| JP4671962B2 (ja) | 2011-04-20 |
| AU2004269896B2 (en) | 2009-11-19 |
| WO2005023273A1 (en) | 2005-03-17 |
| PT1660100E (pt) | 2008-10-14 |
| US20140005256A1 (en) | 2014-01-02 |
| CN1845746A (zh) | 2006-10-11 |
| AU2004269896A1 (en) | 2005-03-17 |
| IL173785A0 (en) | 2006-07-05 |
| MXPA06002489A (es) | 2006-06-20 |
| US8551967B2 (en) | 2013-10-08 |
| EP1660100B1 (de) | 2008-07-02 |
| CA2537226C (en) | 2016-05-03 |
| KR20060061367A (ko) | 2006-06-07 |
| ITMI20031714A1 (it) | 2005-03-06 |
| CN100490820C (zh) | 2009-05-27 |
| RS20060154A (sr) | 2008-08-07 |
| JP2007504194A (ja) | 2007-03-01 |
| DK1660100T3 (da) | 2008-11-10 |
| UA83500C2 (uk) | 2008-07-25 |
| US20060211646A1 (en) | 2006-09-21 |
| IS8334A (is) | 2006-02-28 |
| CA2537226A1 (en) | 2005-03-17 |
| DE602004014787D1 (de) | 2008-08-14 |
| ATE399558T1 (de) | 2008-07-15 |
| RU2006109210A (ru) | 2007-10-10 |
| ES2308223T3 (es) | 2008-12-01 |
| EP1660100A1 (de) | 2006-05-31 |
| RU2348413C2 (ru) | 2009-03-10 |
| ZA200601852B (en) | 2007-06-27 |
| BRPI0414114A (pt) | 2006-10-31 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC2A | Withdrawal, rejection or dismissal of laid open patent application |