NO20061424L - Fremgangsmote for fremstillingen av THIP - Google Patents
Fremgangsmote for fremstillingen av THIPInfo
- Publication number
- NO20061424L NO20061424L NO20061424A NO20061424A NO20061424L NO 20061424 L NO20061424 L NO 20061424L NO 20061424 A NO20061424 A NO 20061424A NO 20061424 A NO20061424 A NO 20061424A NO 20061424 L NO20061424 L NO 20061424L
- Authority
- NO
- Norway
- Prior art keywords
- thip
- preparation
- alkyl
- acid
- procedure
- Prior art date
Links
- ZXRVKCBLGJOCEE-UHFFFAOYSA-N Gaboxadol Chemical compound C1NCCC2=C1ONC2=O ZXRVKCBLGJOCEE-UHFFFAOYSA-N 0.000 title abstract 4
- 238000000034 method Methods 0.000 title abstract 2
- 239000002253 acid Substances 0.000 abstract 3
- 125000004400 (C1-C12) alkyl group Chemical group 0.000 abstract 2
- 125000003118 aryl group Chemical group 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- 125000004642 (C1-C12) alkoxy group Chemical group 0.000 abstract 1
- 125000006552 (C3-C8) cycloalkyl group Chemical group 0.000 abstract 1
- ZDZDSZQYRBZPNN-UHFFFAOYSA-N 4,5,6,7-tetrahydro-[1,2]oxazolo[5,4-c]pyridin-6-ium-3-olate;hydrochloride Chemical compound Cl.C1NCCC2=C1ONC2=O ZDZDSZQYRBZPNN-UHFFFAOYSA-N 0.000 abstract 1
- 101100277337 Arabidopsis thaliana DDM1 gene Proteins 0.000 abstract 1
- 125000002252 acyl group Chemical group 0.000 abstract 1
- 125000003342 alkenyl group Chemical group 0.000 abstract 1
- 101150113676 chr1 gene Proteins 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000000392 cycloalkenyl group Chemical group 0.000 abstract 1
- 229950004346 gaboxadol Drugs 0.000 abstract 1
- 229910052500 inorganic mineral Inorganic materials 0.000 abstract 1
- 239000000543 intermediate Substances 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 239000011707 mineral Substances 0.000 abstract 1
- 208000019116 sleep disease Diseases 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Anesthesiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Plural Heterocyclic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US50042203P | 2003-09-05 | 2003-09-05 | |
| DKPA200301277 | 2003-09-05 | ||
| PCT/DK2004/000579 WO2005023820A1 (fr) | 2003-09-05 | 2004-09-01 | Procede de production de thip |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NO20061424L true NO20061424L (no) | 2006-03-29 |
Family
ID=58707236
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20061424A NO20061424L (no) | 2003-09-05 | 2006-03-29 | Fremgangsmote for fremstillingen av THIP |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US7371863B2 (fr) |
| EP (1) | EP1664060A1 (fr) |
| JP (1) | JP4745233B2 (fr) |
| KR (1) | KR20060069482A (fr) |
| CN (2) | CN101497619A (fr) |
| AR (1) | AR045540A1 (fr) |
| AU (1) | AU2004270323B2 (fr) |
| BR (1) | BRPI0413741A (fr) |
| CA (1) | CA2537840C (fr) |
| EA (1) | EA200600542A1 (fr) |
| IL (1) | IL174070A (fr) |
| IS (1) | IS8333A (fr) |
| ME (1) | MEP1708A (fr) |
| MX (1) | MXPA06002434A (fr) |
| NO (1) | NO20061424L (fr) |
| NZ (1) | NZ545178A (fr) |
| RS (1) | RS20060157A (fr) |
| UA (1) | UA91496C2 (fr) |
| WO (1) | WO2005023820A1 (fr) |
| ZA (1) | ZA200602178B (fr) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0402118D0 (en) | 2004-01-30 | 2004-03-03 | Merck Sharp & Dohme | Polymorphic forms of a GABAA agonist |
| JP2007530604A (ja) * | 2004-04-02 | 2007-11-01 | ハー・ルンドベック・アクチエゼルスカベット | 呼吸機能障害の治療 |
| CN104974175A (zh) * | 2014-04-11 | 2015-10-14 | 天津药物研究院 | 一种氨甲基羟异恶唑类似物的制备方法 |
| LT3274331T (lt) | 2015-03-24 | 2020-04-10 | H. Lundbeck A/S | 4,5,6,7-tetrahidroizozaksolo[5,4-c]piridin-3-olio gamybos būdas |
| JP2022514194A (ja) | 2018-11-21 | 2022-02-10 | セルテゴ セラピューティクス インコーポレイテッド | 自殺のリスクを低減し、うつ病を迅速に軽減するためのガボキサドール |
| CN111320577B (zh) * | 2018-12-13 | 2023-06-23 | 广东东阳光药业有限公司 | 一种吡啶酰胺的制备方法及其应用 |
| MX2022014599A (es) | 2020-05-20 | 2022-12-16 | Certego Therapeutics Inc | Gaboxadol deuterado en anillo y su uso para el tratamiento de trastornos psiquiatricos. |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK270378A (da) * | 1977-06-20 | 1978-12-21 | Krogsgaard Larsen P | Isoxazolderivater |
| DE3145473A1 (de) * | 1980-11-27 | 1982-08-26 | Kefalas A/S, Koebenhavn-Valby | 2-substituierte 4,5,6,7-tetrahydroisoxazolo (5,4-c) pyridin-3-on-verbindungen, verfahren zu ihrer herstellung und diese enthaltende arzneimittel |
| GB2088370B (en) * | 1980-11-27 | 1984-08-01 | Kefalas As | Tetrahydroisoxazolopyridine compounds |
| US4353910A (en) * | 1981-11-27 | 1982-10-12 | Kefalas A/S | Derivatives of 4,5,6,7-tetrahydroisoxazolo [5,4-c] pyridine-3-one, pharmaceutical compositions and methods of treatment |
| DE19525598C2 (de) | 1995-07-13 | 1997-09-25 | Max Planck Gesellschaft | Schlafmittel |
-
2004
- 2004-08-30 AR ARP040103118A patent/AR045540A1/es not_active Application Discontinuation
- 2004-09-01 ME MEP-17/08A patent/MEP1708A/xx unknown
- 2004-09-01 KR KR1020067004221A patent/KR20060069482A/ko not_active Abandoned
- 2004-09-01 MX MXPA06002434A patent/MXPA06002434A/es active IP Right Grant
- 2004-09-01 NZ NZ545178A patent/NZ545178A/en not_active IP Right Cessation
- 2004-09-01 BR BRPI0413741-8A patent/BRPI0413741A/pt not_active IP Right Cessation
- 2004-09-01 EP EP04762799A patent/EP1664060A1/fr not_active Withdrawn
- 2004-09-01 JP JP2006525046A patent/JP4745233B2/ja not_active Expired - Fee Related
- 2004-09-01 UA UAA200603678A patent/UA91496C2/ru unknown
- 2004-09-01 CN CNA2009100081718A patent/CN101497619A/zh active Pending
- 2004-09-01 WO PCT/DK2004/000579 patent/WO2005023820A1/fr not_active Ceased
- 2004-09-01 AU AU2004270323A patent/AU2004270323B2/en not_active Ceased
- 2004-09-01 CN CNB2004800254248A patent/CN100482668C/zh not_active Expired - Fee Related
- 2004-09-01 RS YUP-2006/0157A patent/RS20060157A/sr unknown
- 2004-09-01 CA CA2537840A patent/CA2537840C/fr not_active Expired - Fee Related
- 2004-09-01 US US10/570,551 patent/US7371863B2/en not_active Expired - Fee Related
- 2004-09-01 EA EA200600542A patent/EA200600542A1/ru unknown
- 2004-09-01 ZA ZA200602178A patent/ZA200602178B/en unknown
-
2006
- 2006-02-28 IS IS8333A patent/IS8333A/is unknown
- 2006-03-02 IL IL174070A patent/IL174070A/en not_active IP Right Cessation
- 2006-03-29 NO NO20061424A patent/NO20061424L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| EP1664060A1 (fr) | 2006-06-07 |
| WO2005023820A1 (fr) | 2005-03-17 |
| HK1096398A1 (en) | 2007-06-01 |
| EA200600542A1 (ru) | 2006-08-25 |
| JP4745233B2 (ja) | 2011-08-10 |
| CN100482668C (zh) | 2009-04-29 |
| IL174070A (en) | 2011-03-31 |
| US7371863B2 (en) | 2008-05-13 |
| IS8333A (is) | 2006-02-28 |
| CA2537840C (fr) | 2011-10-25 |
| AR045540A1 (es) | 2005-11-02 |
| AU2004270323A1 (en) | 2005-03-17 |
| US20070112198A1 (en) | 2007-05-17 |
| NZ545178A (en) | 2009-11-27 |
| IL174070A0 (en) | 2006-08-01 |
| JP2007504179A (ja) | 2007-03-01 |
| MEP1708A (xx) | 2010-02-10 |
| CN101497619A (zh) | 2009-08-05 |
| CN1845928A (zh) | 2006-10-11 |
| CA2537840A1 (fr) | 2005-03-17 |
| BRPI0413741A (pt) | 2006-10-24 |
| ZA200602178B (en) | 2007-07-25 |
| UA91496C2 (en) | 2010-08-10 |
| RS20060157A (sr) | 2008-06-05 |
| KR20060069482A (ko) | 2006-06-21 |
| AU2004270323B2 (en) | 2010-01-07 |
| MXPA06002434A (es) | 2006-06-20 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| NO20065830L (no) | Substituerte 2-kinolyloksazoler som er anvendbare som PDE4-inhibitorer. | |
| NO902214D0 (no) | Fremgangsmaate for fremstilling av n-(aryloksyalkyl)-heteroarylpiperidiner og -heteroarylpiperaziner og deres anvendelse som medikamenter. | |
| PE20051039A1 (es) | [1,8] naftiridin-2-onas y compuestos relacionados | |
| CA2324418A1 (fr) | Nouveaux composes opiaces et leurs procedes de preparation et d'utilisation | |
| PE20050480A1 (es) | Acido [2-(8,9-dioxo-2,6-diazabiciclo [5.2.0] non-1(7)-en-2-il)alquil]fosfonico y derivados | |
| PL2428519T3 (pl) | Kompozycja do wytwarzania 17-winylo-trifluorometanosulfonianów jako związków pośrednich | |
| HRP20070430T3 (en) | (3-oxo-3,4-dihydro-quinoxalin-2-yl-amino)-benzamide derivatives and related compounds as glycogen phosphorylase inhibitors for the treatment of diabetes and obesity | |
| PE20091887A1 (es) | Fenoxibenzamidas sustituidas | |
| NO20081056L (no) | Nye, heterosykliske NF-kB-inhibitorer | |
| NO20061424L (no) | Fremgangsmote for fremstillingen av THIP | |
| NO20082226L (no) | 6-heteroarylpyridoindolonderivater, deres fremstilling og terapeutisk anvendelse derav | |
| DE602006008962D1 (de) | Verfahren zur herstellung von valsartan | |
| AR023914A1 (es) | Caprolactamas sustituidas, un proceso para su preparacion, composiciones farmaceuticas que las contienen, y su uso para la preparacion de composicionesfarmaceuticas en el tratamiento de tumores | |
| NO20070972L (no) | Benzyloksyderivater som MAOB-inhibitorer | |
| NO20073213L (no) | Fremgangsmate for fremstilling av tiofenglykosidderivater | |
| MXPA05012360A (es) | Derivados de benzotiazol como ligandos receptores de adenosina. | |
| EE05136B1 (et) | Asendatud imidasopridiinhendite valmistamise meetod | |
| NO20002315L (no) | Nye 1-aza-2-alkyl-6-aryl-cykloalkanforbindelser, fremgangsmÕte ved deres fremstilling og farmasøytiske sammensetninger inneholdende dem | |
| BG106846A (en) | Novel heteroaryl derivatives, their preparation and use | |
| FI20030026A0 (fi) | Menetelmä substituoitujen imidatsolijohdannaisten valmistamiseksi ja menetelmässä käytettäviä välituotteita | |
| DE69107561D1 (de) | Verfahren zur Herstellung von 4-Methylsulfonylbenzoesäurederivate und Zwischenprodukte. | |
| JP2005520942A5 (fr) | ||
| NO20070610L (no) | Fremgangsmate for fremstilling av synteseintermediater anvendelige ved fremstilling av pyrazolforbindelser. | |
| DK2264019T3 (da) | Mellemforbindelser til fremstilling af taxanderivater | |
| BR0105801B1 (pt) | processo para produÇço de derivado alquilamina substituÍdo. |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| CREP | Change of representative |
Representative=s name: PLOUGMANN & VINGTOFT, POSTBOKS 1003 SENTRUM, 0104 |
|
| FC2A | Withdrawal, rejection or dismissal of laid open patent application |