NO20061537L - Fremgangsmate for a levere legemidler til hjernen - Google Patents
Fremgangsmate for a levere legemidler til hjernenInfo
- Publication number
- NO20061537L NO20061537L NO20061537A NO20061537A NO20061537L NO 20061537 L NO20061537 L NO 20061537L NO 20061537 A NO20061537 A NO 20061537A NO 20061537 A NO20061537 A NO 20061537A NO 20061537 L NO20061537 L NO 20061537L
- Authority
- NO
- Norway
- Prior art keywords
- brain
- dispersion
- particles
- pharmaceutical preparation
- mammal
- Prior art date
Links
- 210000004556 brain Anatomy 0.000 title abstract 3
- 238000000034 method Methods 0.000 title abstract 2
- 239000003814 drug Substances 0.000 title 1
- 229940079593 drug Drugs 0.000 title 1
- 239000002245 particle Substances 0.000 abstract 4
- 239000006185 dispersion Substances 0.000 abstract 3
- 239000000825 pharmaceutical preparation Substances 0.000 abstract 3
- 241000124008 Mammalia Species 0.000 abstract 2
- 208000014644 Brain disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 208000035475 disorder Diseases 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0085—Brain, e.g. brain implants; Spinal cord
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
- A61K47/6901—Conjugates being cells, cell fragments, viruses, ghosts, red blood cells or viral vectors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/51—Nanocapsules; Nanoparticles
- A61K9/5107—Excipients; Inactive ingredients
- A61K9/5123—Organic compounds, e.g. fats, sugars
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/51—Nanocapsules; Nanoparticles
- A61K9/5107—Excipients; Inactive ingredients
- A61K9/513—Organic macromolecular compounds; Dendrimers
- A61K9/5146—Organic macromolecular compounds; Dendrimers obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyamines, polyanhydrides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Biomedical Technology (AREA)
- Nanotechnology (AREA)
- Physics & Mathematics (AREA)
- Optics & Photonics (AREA)
- Psychology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Cell Biology (AREA)
- Hematology (AREA)
- Virology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US48209603P | 2003-06-24 | 2003-06-24 | |
| PCT/US2004/018850 WO2004112747A2 (fr) | 2003-06-24 | 2004-06-15 | Methode d'administration de medicaments au cerveau |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NO20061537L true NO20061537L (no) | 2006-04-04 |
Family
ID=33539336
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20061537A NO20061537L (no) | 2003-06-24 | 2006-04-04 | Fremgangsmate for a levere legemidler til hjernen |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US9044381B2 (fr) |
| EP (1) | EP1663158A2 (fr) |
| AU (1) | AU2004249172A1 (fr) |
| BR (1) | BRPI0414970A2 (fr) |
| CA (1) | CA2540695A1 (fr) |
| NO (1) | NO20061537L (fr) |
| WO (1) | WO2004112747A2 (fr) |
| ZA (1) | ZA200603062B (fr) |
Families Citing this family (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1558755A (zh) | 2001-09-26 | 2004-12-29 | ���ع��ʹ�˾ | 通过分散和除去溶剂或液相制备亚微米大小的纳米颗粒 |
| US8986736B2 (en) * | 2003-06-24 | 2015-03-24 | Baxter International Inc. | Method for delivering particulate drugs to tissues |
| BRPI0414970A2 (pt) | 2003-06-24 | 2012-12-11 | Baxter Int | método para transporte de drogas ao cérebro |
| RU2006130958A (ru) * | 2004-01-29 | 2008-03-10 | Бакстер Интернэшнл Инк. (Us) | Наносуспензии антиретровирусных агентов для улучшенной доставки в центральную нервную систему |
| CN101005842A (zh) * | 2004-05-28 | 2007-07-25 | 弗特克斯药品有限公司 | 蕈毒碱性受体调节剂 |
| CA2565972A1 (fr) | 2004-06-15 | 2005-12-29 | Baxter International Inc. | Application ex-vivo d'agents therapeutiques microparticulaires solides |
| WO2006097725A2 (fr) * | 2005-03-15 | 2006-09-21 | Queen Mary & Westfield College | Preparations pharmaceutiques comprenant des microparticules penetrant les neurones |
| WO2006126208A2 (fr) | 2005-05-26 | 2006-11-30 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | Compositions et methodes d'utilisation desdites compositions dans l'administration d'agents dans un organe cible protege par une barriere sanguine |
| US20080274202A1 (en) * | 2005-08-01 | 2008-11-06 | Kraig Richard P | Compositions and Method for Brain Specific Targeted Delivery of Therapeutic Agents |
| KR100762954B1 (ko) * | 2006-01-26 | 2007-10-04 | 나재운 | 항암제가 봉입된, 소수성 담즙산이 결합된 친수성 키토산올리고당 나노입자 및 그 제조방법 |
| KR100785656B1 (ko) * | 2007-05-14 | 2007-12-17 | 재단법인서울대학교산학협력재단 | 소염제로 사용되는 소디움글리코콜레이트 또는 그 유도체 |
| EP2170283B1 (fr) | 2007-06-22 | 2019-01-09 | Board of Regents, The University of Texas System | Formation de particules de peptide ou de protéine submicroniques stables par congélation de film mince |
| WO2009111638A1 (fr) * | 2008-03-05 | 2009-09-11 | Baxter International Inc. | Compositions et procédés d’administration de médicament |
| JP5711138B2 (ja) | 2008-11-16 | 2015-04-30 | ボード・オブ・リージエンツ,ザ・ユニバーシテイ・オブ・テキサス・システム | 高濃度の低粘度懸濁液 |
| WO2010068899A1 (fr) | 2008-12-12 | 2010-06-17 | Creighton University | Nanoparticules comprenant des combinaisons d'agents antirétroviraux, et utilisations de celles-ci |
| US10952965B2 (en) | 2009-05-15 | 2021-03-23 | Baxter International Inc. | Compositions and methods for drug delivery |
| DK2921486T3 (da) | 2009-08-07 | 2017-11-13 | American Life Science Pharmaceuticals Inc | Sammensætninger og fremgangsmåder til behandling af beta-amyloid-relaterede sygdomme |
| CN106983862A (zh) * | 2010-03-22 | 2017-07-28 | 弗·哈夫曼-拉罗切有限公司 | 对于稳定含有蛋白质的制剂有用的组合物和方法 |
| JP2013542945A (ja) * | 2010-11-02 | 2013-11-28 | ボード オブ リージェンツ オブ ザ ユニバーシティ オブ ネブラスカ | 治療を送達するための組成物および方法 |
| WO2012138003A1 (fr) * | 2011-04-08 | 2012-10-11 | 경북대학교 산학협력단 | Utilisations d'un dérivé d'héparine-acide biliaire désulfaté pour la prévention et le traitement de maladies inflammatoires |
| DE102012009570A1 (de) | 2012-05-09 | 2013-11-14 | Naum Goldstein | Komposition für nasale Anwendung |
| DE102012015248A1 (de) * | 2012-08-05 | 2014-02-06 | Naum Goldstein | Verfahren zur Einbringung biologisch aktiver Substanzen ins Gehirn |
| US9808428B2 (en) | 2014-01-14 | 2017-11-07 | Board Of Regents Of The University Of Nebraska | Compositions and methods for the delivery of therapeutics |
| EP3203995A4 (fr) | 2014-10-09 | 2019-05-15 | Board of Regents of the University of Nebraska | Compositions et méthodes d'administration d'agents thérapeutiques |
| US10123969B2 (en) | 2015-10-15 | 2018-11-13 | Wisconsin Alumni Research Foundation | Osmotic enhancement of drug/therapeutic delivery to the brain following infusion or injection into the cerebrospinal fluid |
| EP3737359A4 (fr) | 2018-01-12 | 2021-11-03 | Board of Regents of the University of Nebraska | Promédicaments antiviraux et formulations de ceux-ci |
| CA3132832A1 (fr) | 2018-04-09 | 2019-10-17 | Howard E. Gendelman | Promedicaments antiviraux et formulations de ceux-ci |
| AU2021206286A1 (en) | 2020-01-10 | 2024-08-08 | Consynance Therapeutics, Inc. | Therapeutic combinations of drugs and methods of using them |
| BR112022014529A2 (pt) * | 2020-01-23 | 2022-09-20 | Axcess Uk Ltd | Absorção celular |
| JP2024526956A (ja) | 2021-07-22 | 2024-07-19 | ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア | 精製ヒトrna編集酵素を使用するための組成物および方法 |
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| DE2655801C2 (de) * | 1976-12-09 | 1986-06-26 | Kernforschungsanlage Jülich GmbH, 5170 Jülich | Injizierbare Suspension von Membranvesikeln aus Erythrozyten und Verfahren zur Herstellung der Suspension |
| DE2656317C2 (de) * | 1976-12-11 | 1986-06-19 | Kernforschungsanlage Jülich GmbH, 5170 Jülich | Verfahren zur Herstellung einer Suspension von beladenen Erythrocyten |
| DE2656746C2 (de) * | 1976-12-15 | 1986-06-26 | Kernforschungsanlage Jülich GmbH, 5170 Jülich | Verwendung von beladenen Erythrozyten |
| JPS60150826A (ja) | 1984-01-18 | 1985-08-08 | Lion Corp | 表面電荷をもつベシクル分散液 |
| US4670185A (en) * | 1982-07-19 | 1987-06-02 | Lion Corporation | Aqueous vesicle dispersion having surface charge |
| US4608278A (en) * | 1983-06-22 | 1986-08-26 | The Ohio State University Research Foundation | Small particule formation and encapsulation |
| US4826689A (en) * | 1984-05-21 | 1989-05-02 | University Of Rochester | Method for making uniformly sized particles from water-insoluble organic compounds |
| CA1338736C (fr) * | 1986-12-05 | 1996-11-26 | Roger Baurain | Microcristaux comportant une substance active presentant une affinite pour les phospholipides, et au moins un phospholipide, procede de preparation |
| FR2608988B1 (fr) * | 1986-12-31 | 1991-01-11 | Centre Nat Rech Scient | Procede de preparation de systemes colloidaux dispersibles d'une substance, sous forme de nanoparticules |
| US5213788A (en) | 1988-09-29 | 1993-05-25 | Ranney David F | Physically and chemically stabilized polyatomic clusters for magnetic resonance image and spectral enhancement |
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| WO1994007999A1 (fr) | 1992-09-28 | 1994-04-14 | Brown University Research Foundation | Matrices en chitosan pour cellules encapsulees |
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| US6902743B1 (en) * | 1995-05-22 | 2005-06-07 | The United States Of America As Represented By The Secretary Of The Army | Therapeutic treatment and prevention of infections with a bioactive material(s) encapuslated within a biodegradable-bio-compatable polymeric matrix |
| US6143211A (en) * | 1995-07-21 | 2000-11-07 | Brown University Foundation | Process for preparing microparticles through phase inversion phenomena |
| US6331299B1 (en) * | 1995-08-18 | 2001-12-18 | Sloan-Kettering Institute For Cancer Research | Method for treatment of cancer and infectious disease and compositions useful in same |
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| CA2234957C (fr) | 1995-10-17 | 2006-12-19 | Inge B. Henriksen | Administration de medicaments insolubles |
| JP2000514440A (ja) * | 1996-07-09 | 2000-10-31 | ザ ジョーンズ ホプキンス ユニバーシティー | 遺伝子輸送システム |
| US6045829A (en) * | 1997-02-13 | 2000-04-04 | Elan Pharma International Limited | Nanocrystalline formulations of human immunodeficiency virus (HIV) protease inhibitors using cellulosic surface stabilizers |
| WO1998035666A1 (fr) * | 1997-02-13 | 1998-08-20 | Nanosystems Llc | Preparation de pastilles de naproxene nanoparticulaire |
| AU7133898A (en) | 1997-04-18 | 1998-11-13 | Vertex Pharmaceuticals Incorporated | Nanosized aspartyl protease inhibitors |
| US20020068048A1 (en) | 1997-09-05 | 2002-06-06 | Patrick A. Dreyfus | Method for the treatment or diagnosis of human pathologies with disseminated or difficult to access cells or tissues |
| US6638621B2 (en) * | 2000-08-16 | 2003-10-28 | Lyotropic Therapeutics, Inc. | Coated particles, methods of making and using |
| US6645464B1 (en) * | 1998-07-30 | 2003-11-11 | James F. Hainfeld | Loading metal particles into cell membrane vesicles and metal particular use for imaging and therapy |
| WO2000064954A1 (fr) | 1999-04-22 | 2000-11-02 | Vanderbilt University | Systeme d'encapsulation de polymeres facilitant l'angiogenese |
| US20050112141A1 (en) * | 2000-08-30 | 2005-05-26 | Terman David S. | Compositions and methods for treatment of neoplastic disease |
| HUP0202669A3 (en) | 1999-09-09 | 2004-06-28 | Univ California | Cationic liposome delivery of taxanes to angiogenic bloos vessels |
| US6458387B1 (en) * | 1999-10-18 | 2002-10-01 | Epic Therapeutics, Inc. | Sustained release microspheres |
| GB0002856D0 (en) | 2000-02-08 | 2000-03-29 | Gendel Limited | Ultrasound sensitisation |
| JP4085231B2 (ja) * | 2000-02-28 | 2008-05-14 | 株式会社ビークル | タンパク質中空ナノ粒子とそれを用いた物質運搬体、ならびに細胞への物質導入方法 |
| CN1406140A (zh) * | 2000-02-28 | 2003-03-26 | 吉倪塞思公司 | 纳米胶囊包封系统与方法 |
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| PL366025A1 (en) | 2000-05-03 | 2005-01-24 | Munich Biotech Ag | Cationic diagnostic, imaging and therapeutic agents associated with activated vascular sites |
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| US6627442B1 (en) | 2000-08-31 | 2003-09-30 | Virxsys Corporation | Methods for stable transduction of cells with hiv-derived viral vectors |
| DE60138641D1 (de) * | 2000-10-27 | 2009-06-18 | Baxter Healthcare Sa | Herstellung von mikrokügelchen |
| US9700866B2 (en) * | 2000-12-22 | 2017-07-11 | Baxter International Inc. | Surfactant systems for delivery of organic compounds |
| WO2002055059A2 (fr) | 2000-12-22 | 2002-07-18 | Baxter Int | Preparation de suspensions de particules submicroniques |
| US7037528B2 (en) * | 2000-12-22 | 2006-05-02 | Baxter International Inc. | Microprecipitation method for preparing submicron suspensions |
| US6884436B2 (en) * | 2000-12-22 | 2005-04-26 | Baxter International Inc. | Method for preparing submicron particle suspensions |
| US20040022861A1 (en) * | 2001-01-30 | 2004-02-05 | Williams Robert O. | Process for production of nanoparticles and microparticles by spray freezing into liquid |
| WO2002060416A1 (fr) | 2001-02-01 | 2002-08-08 | Gendel Limited | Systeme d'administration de polypeptide et leur procede de preparation |
| US20020169102A1 (en) * | 2001-04-03 | 2002-11-14 | Frey William H. | Intranasal delivery of agents for regulating development of implanted cells in the CNS |
| US6790455B2 (en) * | 2001-09-14 | 2004-09-14 | The Research Foundation At State University Of New York | Cell delivery system comprising a fibrous matrix and cells |
| US20060003012A9 (en) * | 2001-09-26 | 2006-01-05 | Sean Brynjelsen | Preparation of submicron solid particle suspensions by sonication of multiphase systems |
| GB0224442D0 (en) | 2002-10-21 | 2002-11-27 | Molmed Spa | A delivery system |
| EP1628641A2 (fr) * | 2003-05-19 | 2006-03-01 | Baxter International Inc. | Preparations pharmaceutiques de petites particules d'anticonvulsivants et d'agents contre la demence et agents immmunosupresseurs |
| CA2528869A1 (fr) | 2003-06-12 | 2004-12-23 | Regents Of The University Of Minnesota | Methode pour diriger des cellules sur des tissus ou des organes cibles |
| EP1567188B1 (fr) | 2003-06-20 | 2012-07-11 | Eli Lilly And Company | Particules virales modifiees possedant des proprietes immunogenes et une teneur limitee en lipides utiles pour traiter et prevenir des maladies infectieuses |
| BRPI0414970A2 (pt) | 2003-06-24 | 2012-12-11 | Baxter Int | método para transporte de drogas ao cérebro |
| US20050084456A1 (en) * | 2003-10-21 | 2005-04-21 | Liping Tang | Functionalized particles |
| GB0329310D0 (en) | 2003-12-18 | 2004-01-21 | Univ Keele | Method |
| RU2006130958A (ru) | 2004-01-29 | 2008-03-10 | Бакстер Интернэшнл Инк. (Us) | Наносуспензии антиретровирусных агентов для улучшенной доставки в центральную нервную систему |
| AU2005215254B2 (en) | 2004-02-02 | 2009-11-12 | Engeneic Molecular Delivery Pty Ltd | Compositions and methods for targeted in vitro and in vivo drug delivery to mammalian cells via bacterially derived intact minicells |
| CA2565972A1 (fr) | 2004-06-15 | 2005-12-29 | Baxter International Inc. | Application ex-vivo d'agents therapeutiques microparticulaires solides |
| JPWO2006080243A1 (ja) | 2005-01-28 | 2008-06-19 | コニカミノルタエムジー株式会社 | 被覆磁性粒子含有製剤およびその製造方法、並びに診断治療システム |
| JP5700909B2 (ja) | 2005-05-04 | 2015-04-15 | メディゲーネ アクチエンゲゼルシャフトMediGene AG | パクリタキセルを含む陽イオン性リポソーム製剤を投与する方法 |
| CN1772303A (zh) | 2005-10-25 | 2006-05-17 | 朱宏 | 恶性肿瘤磁热疗用纳米磁粉-抗体靶向药物 |
-
2004
- 2004-06-15 BR BRPI0414970-0A patent/BRPI0414970A2/pt not_active Application Discontinuation
- 2004-06-15 CA CA002540695A patent/CA2540695A1/fr not_active Abandoned
- 2004-06-15 AU AU2004249172A patent/AU2004249172A1/en not_active Abandoned
- 2004-06-15 WO PCT/US2004/018850 patent/WO2004112747A2/fr not_active Ceased
- 2004-06-15 US US10/868,680 patent/US9044381B2/en active Active
- 2004-06-15 EP EP04776540A patent/EP1663158A2/fr not_active Withdrawn
-
2006
- 2006-04-04 NO NO20061537A patent/NO20061537L/no not_active Application Discontinuation
- 2006-04-18 ZA ZA200603062A patent/ZA200603062B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| WO2004112747A2 (fr) | 2004-12-29 |
| BRPI0414970A2 (pt) | 2012-12-11 |
| EP1663158A2 (fr) | 2006-06-07 |
| ZA200603062B (en) | 2007-04-25 |
| CA2540695A1 (fr) | 2004-12-29 |
| US9044381B2 (en) | 2015-06-02 |
| US20050048002A1 (en) | 2005-03-03 |
| WO2004112747A3 (fr) | 2005-03-03 |
| AU2004249172A1 (en) | 2004-12-29 |
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