NO20061646L - Plasminogenaktivatorer som har redusert lysinbindingskapasitet - Google Patents

Plasminogenaktivatorer som har redusert lysinbindingskapasitet

Info

Publication number
NO20061646L
NO20061646L NO20061646A NO20061646A NO20061646L NO 20061646 L NO20061646 L NO 20061646L NO 20061646 A NO20061646 A NO 20061646A NO 20061646 A NO20061646 A NO 20061646A NO 20061646 L NO20061646 L NO 20061646L
Authority
NO
Norway
Prior art keywords
binding capacity
plasminogen activators
reduced light
light binding
plasminogen
Prior art date
Application number
NO20061646A
Other languages
English (en)
Norwegian (no)
Inventor
Wolfgang Sohngen
Oliver Kops
Vincent Ellis
Original Assignee
Paion Deutschland Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Paion Deutschland Gmbh filed Critical Paion Deutschland Gmbh
Publication of NO20061646L publication Critical patent/NO20061646L/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/48Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424Serine endopeptidases (3.4.21)
    • C12N9/6456Plasminogen activators
    • C12N9/6459Plasminogen activators t-plasminogen activator (3.4.21.68), i.e. tPA
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46Hydrolases (3)
    • A61K38/48Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/49Urokinase; Tissue plasminogen activator
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y304/00Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21Serine endopeptidases (3.4.21)
    • C12Y304/21069Protein C activated (3.4.21.69)

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Zoology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biotechnology (AREA)
  • Epidemiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Hematology (AREA)
  • Microbiology (AREA)
  • Diabetes (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Peptides Or Proteins (AREA)
NO20061646A 2003-09-12 2006-04-11 Plasminogenaktivatorer som har redusert lysinbindingskapasitet NO20061646L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10342518A DE10342518A1 (de) 2003-09-12 2003-09-12 Plasminogen-Aktivatoren mit verringerter Lysin-Bindungskapazität
PCT/EP2004/010220 WO2005026341A2 (fr) 2003-09-12 2004-09-13 Activateurs plasminogenes a capacite de liaison lysine reduite

Publications (1)

Publication Number Publication Date
NO20061646L true NO20061646L (no) 2006-04-11

Family

ID=34305758

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20061646A NO20061646L (no) 2003-09-12 2006-04-11 Plasminogenaktivatorer som har redusert lysinbindingskapasitet

Country Status (14)

Country Link
EP (2) EP1664293A2 (fr)
JP (1) JP2007505079A (fr)
CN (1) CN1849394A (fr)
AU (1) AU2004272731A1 (fr)
BR (1) BRPI0413718A (fr)
CA (1) CA2537696A1 (fr)
DE (1) DE10342518A1 (fr)
EA (2) EA011156B1 (fr)
IL (1) IL173953A0 (fr)
MX (1) MXPA06002756A (fr)
NO (1) NO20061646L (fr)
NZ (1) NZ545825A (fr)
WO (1) WO2005026341A2 (fr)
ZA (1) ZA200602716B (fr)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8430749B2 (en) 2001-08-10 2013-04-30 Igt Dynamic casino tracking and optimization
US7946917B2 (en) 2001-08-10 2011-05-24 Igt Flexible loyalty points programs
DE10153601A1 (de) 2001-11-02 2003-05-22 Paion Gmbh DSPA zur Behandlung von Schlaganfall
DE10342518A1 (de) 2003-09-12 2005-05-12 Paion Gmbh Plasminogen-Aktivatoren mit verringerter Lysin-Bindungskapazität
IL190184A0 (en) * 2008-03-16 2009-02-11 Hadasit Med Res Service tPA MUTANT IN THE TREATMENT OF ACUTE BRAIN INJURY AND NEURODEGENERATIVE DISORDERS

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4766075A (en) 1982-07-14 1988-08-23 Genentech, Inc. Human tissue plasminogen activator
US5094953A (en) * 1988-03-21 1992-03-10 Genentech, Inc. Human tissue plasminogen activator variants
IE69054B1 (en) * 1988-07-20 1996-08-07 Schering Ag Vampire bat salivary plasminogen activators
DE3825253A1 (de) * 1988-07-25 1990-02-01 Boehringer Mannheim Gmbh T-pa-derivat und seine herstellung
US5714145A (en) * 1988-09-02 1998-02-03 Genentech, Inc. Tissue plasminogen activator having zymogenic or fibrin specific properties
ES2085326T3 (es) * 1989-02-13 1996-06-01 Schering Ag Activador de plasminogeno salivar del murcielago vampiro vpa-alfa1.
US6008019A (en) 1989-02-13 1999-12-28 Schering Aktiengesellschaft Plasminogen activator from saliva of the vampire bat
AU665979B2 (en) * 1991-12-16 1996-01-25 Genentech Inc. t-PA substitution variants with improved fibrin-specificity
DE4423574A1 (de) * 1994-07-05 1996-01-11 Boehringer Mannheim Gmbh Nicht-glykosylierte Plasminogenaktivator-Derivate und ihre Verwendung bei erhöhtem Blutungsrisiko
DE10153601A1 (de) * 2001-11-02 2003-05-22 Paion Gmbh DSPA zur Behandlung von Schlaganfall
EP1622639B1 (fr) * 2003-05-02 2013-01-16 Lundbeck, H., A/S Injection intraveineuse d'activateurs de plasminogene non neurotoxiques pour le traitement de l'attaque cerebrale
DE10342518A1 (de) 2003-09-12 2005-05-12 Paion Gmbh Plasminogen-Aktivatoren mit verringerter Lysin-Bindungskapazität

Also Published As

Publication number Publication date
WO2005026341A3 (fr) 2005-09-01
CN1849394A (zh) 2006-10-18
DE10342518A1 (de) 2005-05-12
EA200600573A1 (ru) 2006-08-25
MXPA06002756A (es) 2007-08-24
EP1664293A2 (fr) 2006-06-07
BRPI0413718A (pt) 2006-10-17
IL173953A0 (en) 2006-07-05
CA2537696A1 (fr) 2005-03-24
NZ545825A (en) 2009-08-28
EP2368984A1 (fr) 2011-09-28
ZA200602716B (en) 2007-07-25
JP2007505079A (ja) 2007-03-08
EA011156B1 (ru) 2009-02-27
EA200801861A1 (ru) 2010-06-30
WO2005026341A2 (fr) 2005-03-24
AU2004272731A1 (en) 2005-03-24

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Legal Events

Date Code Title Description
FC2A Withdrawal, rejection or dismissal of laid open patent application