NO20062050L - Terapeutiske kombinasjoner av antihypertensive og antiangiogene midler - Google Patents

Terapeutiske kombinasjoner av antihypertensive og antiangiogene midler

Info

Publication number
NO20062050L
NO20062050L NO20062050A NO20062050A NO20062050L NO 20062050 L NO20062050 L NO 20062050L NO 20062050 A NO20062050 A NO 20062050A NO 20062050 A NO20062050 A NO 20062050A NO 20062050 L NO20062050 L NO 20062050L
Authority
NO
Norway
Prior art keywords
antihypertensive
agent
therapeutic combinations
antiangiogenic agents
angiogenesis
Prior art date
Application number
NO20062050A
Other languages
English (en)
Other versions
NO326277B1 (no
Inventor
Jon Owen Curwen
Donald James Ogilvie
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Publication of NO20062050L publication Critical patent/NO20062050L/no
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of NO326277B1 publication Critical patent/NO326277B1/no

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/517Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/55Protease inhibitors
    • A61K38/556Angiotensin converting enzyme inhibitors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/06Antipsoriatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/48Drugs for disorders of the endocrine system of the pancreatic hormones
    • A61P5/50Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Immunology (AREA)
  • Cardiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Dermatology (AREA)
  • Vascular Medicine (AREA)
  • Emergency Medicine (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
NO20062050A 2000-04-05 2006-05-08 Anvendelse av terapeutiske kombinasjoner av et vaskulaert malmiddel og et anti-hypertensivt middel for fremstilling av medikament for behandling av sykdom samt et farmasoytisk preparat omfattende disse NO326277B1 (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB0008269.3A GB0008269D0 (en) 2000-04-05 2000-04-05 Combination chemotherapy

Publications (2)

Publication Number Publication Date
NO20062050L true NO20062050L (no) 2001-10-08
NO326277B1 NO326277B1 (no) 2008-10-27

Family

ID=9889176

Family Applications (2)

Application Number Title Priority Date Filing Date
NO20024814A NO323467B1 (no) 2000-04-05 2002-10-04 Farmasoytisk sammensetning som omfatter antihypertensivt middel og en VEGF-reseptortyrosinkinaseinhibitor, et testsett som omfatter middelet og inhibitorene og anvendelse av dem for fremstilling av et medikament
NO20062050A NO326277B1 (no) 2000-04-05 2006-05-08 Anvendelse av terapeutiske kombinasjoner av et vaskulaert malmiddel og et anti-hypertensivt middel for fremstilling av medikament for behandling av sykdom samt et farmasoytisk preparat omfattende disse

Family Applications Before (1)

Application Number Title Priority Date Filing Date
NO20024814A NO323467B1 (no) 2000-04-05 2002-10-04 Farmasoytisk sammensetning som omfatter antihypertensivt middel og en VEGF-reseptortyrosinkinaseinhibitor, et testsett som omfatter middelet og inhibitorene og anvendelse av dem for fremstilling av et medikament

Country Status (29)

Country Link
US (1) US7829573B2 (no)
EP (3) EP1790340A3 (no)
JP (1) JP2003528917A (no)
KR (2) KR20080034523A (no)
CN (1) CN1431902A (no)
AT (1) ATE355065T1 (no)
AU (2) AU4438601A (no)
BR (1) BR0109729A (no)
CA (1) CA2401854A1 (no)
CY (1) CY1107615T1 (no)
CZ (1) CZ299410B6 (no)
DE (1) DE60126923T2 (no)
DK (1) DK1272186T3 (no)
EE (1) EE200200578A (no)
ES (1) ES2280349T3 (no)
GB (1) GB0008269D0 (no)
HU (1) HUP0300426A2 (no)
IL (1) IL151503A0 (no)
IS (2) IS2455B (no)
MX (1) MXPA02009743A (no)
NO (2) NO323467B1 (no)
NZ (2) NZ534455A (no)
PL (1) PL357605A1 (no)
PT (1) PT1272186E (no)
RU (1) RU2002129353A (no)
SI (1) SI1272186T1 (no)
SK (1) SK14302002A3 (no)
WO (1) WO2001074360A1 (no)
ZA (1) ZA200206959B (no)

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PT1592423E (pt) 2003-02-13 2011-06-16 Astrazeneca Ab Terapia de combinação de zd6474 com 5-fu e/ou cpt-11
GB0310401D0 (en) 2003-05-07 2003-06-11 Astrazeneca Ab Therapeutic agent
EP1648465B1 (en) 2003-07-10 2010-08-25 AstraZeneca AB Use of the quinazoline derivative zd6474 combined with platinum compounds and optionally ionising radiation in the treatment of diseases associated with angiogenesis and/or increased vascular permeability
GB0316123D0 (en) 2003-07-10 2003-08-13 Astrazeneca Ab Combination therapy
GB0316127D0 (en) 2003-07-10 2003-08-13 Astrazeneca Ab Combination therapy
GB0406446D0 (en) 2004-03-23 2004-04-28 Astrazeneca Ab Combination therapy
GB0406445D0 (en) 2004-03-23 2004-04-28 Astrazeneca Ab Combination therapy
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KR20070072543A (ko) 2004-09-27 2007-07-04 아스트라제네카 아베 Zd6474 및 이마티닙을 포함하는 병합법
GB0424339D0 (en) 2004-11-03 2004-12-08 Astrazeneca Ab Combination therapy
BRPI0612397A2 (pt) 2005-07-06 2011-02-22 Astrazeneca Ab uso de azd2171 ou um sal farmaceuticamente aceitável do mesmo e gencitabina, composição farmacêutica, kit, e, método para a produção de um efeito anti-angiogênico e/ou redutor da permeabilidade vascular em um animal de sangue quente
CA2633211A1 (en) 2005-12-15 2007-06-21 Astrazeneca Ab Combination of angiopoietin-2 antagonist and of vegf-a, kdr and/or flt1 antagonist for treating cancer
WO2007071958A2 (en) 2005-12-22 2007-06-28 Astrazeneca Ab Combination of zd6474 and pemetrexed
ATE502641T1 (de) 2005-12-22 2011-04-15 Astrazeneca Ab Kombination aus azd2171 und pemetrexed
EP2066353B1 (en) 2006-09-29 2013-01-02 AstraZeneca AB Combination of zd6474 and bevacizumab for cancer therapy
US20100130519A1 (en) 2007-04-13 2010-05-27 Stephen Robert Wedge Combination therapy comprising azd2171 and azd6244 or mek-inhibitor ii

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ATE355065T1 (de) 2006-03-15
KR20080034523A (ko) 2008-04-21
EP1790340A2 (en) 2007-05-30
IS8726A (is) 2008-04-16
AU2001244386B2 (en) 2005-01-27
WO2001074360A1 (en) 2001-10-11
ES2280349T3 (es) 2007-09-16
NO326277B1 (no) 2008-10-27
PT1272186E (pt) 2007-04-30
NO20024814L (no) 2002-11-12
NO323467B1 (no) 2007-05-21
KR100849149B1 (ko) 2008-07-31
EP1790340A3 (en) 2009-03-18
DE60126923D1 (de) 2007-04-12
SI1272186T1 (sl) 2007-06-30
DE60126923T2 (de) 2007-10-31
IS2455B (is) 2008-11-15
EP1658849A2 (en) 2006-05-24
EE200200578A (et) 2004-06-15
SK14302002A3 (sk) 2003-05-02
CY1107615T1 (el) 2013-03-13
EP1272186A1 (en) 2003-01-08
NZ534455A (en) 2007-01-26
MXPA02009743A (es) 2003-03-27
KR20030007491A (ko) 2003-01-23
RU2002129353A (ru) 2004-03-20
NO20024814D0 (no) 2002-10-04
US20030144298A1 (en) 2003-07-31
IL151503A0 (en) 2003-04-10
AU4438601A (en) 2001-10-15
PL357605A1 (en) 2004-07-26
EP1658849A3 (en) 2009-02-18
US7829573B2 (en) 2010-11-09
CN1431902A (zh) 2003-07-23
IS6557A (is) 2002-09-20
JP2003528917A (ja) 2003-09-30
CA2401854A1 (en) 2001-10-11
DK1272186T3 (da) 2007-05-21
EP1272186B1 (en) 2007-02-28
BR0109729A (pt) 2003-02-04
GB0008269D0 (en) 2000-05-24
HUP0300426A2 (hu) 2003-06-28
ZA200206959B (en) 2003-12-01
NZ520938A (en) 2005-08-26
CZ299410B6 (cs) 2008-07-16

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